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The map label for this gene is yciR [C]

Identifier: 114798127

GI number: 114798127

Start: 2545312

End: 2547105

Strand: Direct

Name: yciR [C]

Synonym: HNE_2435

Alternate gene names: 114798127

Gene position: 2545312-2547105 (Clockwise)

Preceding gene: 114798242

Following gene: 114797769

Centisome position: 68.7

GC content: 59.14

Gene sequence:

>1794_bases
GTGTCCTTCACCCTCAGCGATGATCATTTCAAACGTCTGTTTCCCGCCTTCATCCAGCTGGACCTGGCTGGCAATATCGT
TTCGGTTGGCCCCTCATTGGAGCGCCTGCTCGGCCCGGGACTGACGGGCCGCCCGTTCTTTGAAACATTCAAGGTGGAAA
CACCCCGCCGGATTGTATCAGCCCAAGGGCTGAACGATCAGCGTGAAGTGACGATCATGATCCGTGCCGGGAAGACAGAC
TTGCGGCTGCGCGGTATCGTTGTGCGCAGCGCGGAGAGCATCTGTCTGCTTGTAGGGCATGTGCCGGATGTGAACGCAGA
AGAAGCCGCATTCATGTTGCGGATGTCTGATTTTTCTCCTGCCGACGGATCGCTTGACCTTCTGGTCGCCGCCCATCTTC
GCAAGGGCTTGCTCCAGGACGCCAAGACGCTGGTGATGGAATTGCAGGAGAAATCGGCCGAAGCCGATGCCCTGGCGCAT
ATGGACCCTCTGACCGCCGTGACGAACCGGCGCGGCTTTTTCCGCAAGCTGGAGGAGCGCCTTTCAATTGCGCGCGCGCA
CAACACGCCGCTGACGGTCGGGGTGATCGATCTGGACGGCTTTAAACCCGTGAACGATATTTTCGGACATGCCGCTGGCG
ATCAGCTCCTGTTCCAAAGCGGCGCGCGCGTGCGCGAGATTGCCGGGCCGAATGGTATTGTCGGGCGGCTCGGAGGGGAC
GAGTTTGGCATTATCCTTCCCGAACTGGGTGATGAGGCGGAAATACTGGAAATCGGTCAGCGGATCTGTGACGCGTTGGC
GGAACCCTTCAAGGTGAAGGAGGGCATTGCCCGGATCGGTGCTTCTGCTGGCTTCGCGGCCTTTCCGCATGCGGGCGATA
CAACTGAGACCCTGTTCGAGCGGGCCGACTATGCGCTCTACCATTCCAAGCAGCAGGAACGCGGCCGGCCGATGGTGTTC
ACCAGCCAGCATGAGCGCGAAATCCGCTATCAGTCGTCGATTGAACAAGGCTTGCGGGAGTCGGCAGATGATGAATTCCA
GATTGTCTACCAACCGATTATCCGGGCCGCCGATGGCAAAACAACCGGCGTGGAAGCGCTTGCGCGCTGGACCTCTCCCC
TTCTGGGGCCCATCCGGCCGGATATTTTCATCCGCGCTGCCGAGCAGAATGGCGCTGTCAGCCGGCTGACCCGCATTCTG
CTGCGGAAAGCATTGAATGATGCGCGCCATTGGCCCGATGATGTGCAGCTCTCTTTCAATCTATCCGCCATAGATCTGTC
ATCGCCGGAAAGCGCGTCCCTGTTGCAGGCGATTATTCTGGACTCAGGATTTCCGCCGCAGCGGCTGATGTTCGAGATTA
CCGAAACGGCCATCATGCAGGACTTTGAACGCGCGCTGGAATGTCTCGGGCTGTTCACCGCGATGGGCGTGCGCATTGCG
CTGGATGATTTCGGGACGGGCTACTCCTCGCTTGGCTACCTTCAGAAAATGCCGATTGACCGGTTGAAAATCGATCGGTC
TTTCACACTGGGTCTGATGACGCGGCGCGGCACACGGAGCATCATGCGATCGATTGTGACCCTGTGCAAAAGTCTCGATA
TCGAATGCGTGGTTGAGGGCGTCTCCAATGGACGCCAGGCGGAGATACTCCGCGAGATGGGCGCGCCCTACCTTCAGGGC
TTTCACTTCTCCCGCGCCATGAGCCAGACACAACTGCTCGAATACCTCACACCCGCAGCAGGATCGGATTGCAGCACCCA
TGATCCGGACGAAGACCTGCGCCGCATGGCTTGA

Upstream 100 bases:

>100_bases
TCGGAGAGACAGGGCGCGTGACGCATGCGGTGACAGATGAAGGCGATGTATTTTCACTCCATTGCGACGCGCGGAACTCC
GCTGCTCCGGGAGCCGCCTA

Downstream 100 bases:

>100_bases
GCCAAGCGCTACTCGCGGAAGGCGCGCTTGAGGGCAAATGCCAGAAAAGGCGGCCAGAGCATCAACGCCAGCAGGCGCAT
GTATACGCCAAACTCCAGCG

Product: putative diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 597; Mature: 596

Protein sequence:

>597_residues
MSFTLSDDHFKRLFPAFIQLDLAGNIVSVGPSLERLLGPGLTGRPFFETFKVETPRRIVSAQGLNDQREVTIMIRAGKTD
LRLRGIVVRSAESICLLVGHVPDVNAEEAAFMLRMSDFSPADGSLDLLVAAHLRKGLLQDAKTLVMELQEKSAEADALAH
MDPLTAVTNRRGFFRKLEERLSIARAHNTPLTVGVIDLDGFKPVNDIFGHAAGDQLLFQSGARVREIAGPNGIVGRLGGD
EFGIILPELGDEAEILEIGQRICDALAEPFKVKEGIARIGASAGFAAFPHAGDTTETLFERADYALYHSKQQERGRPMVF
TSQHEREIRYQSSIEQGLRESADDEFQIVYQPIIRAADGKTTGVEALARWTSPLLGPIRPDIFIRAAEQNGAVSRLTRIL
LRKALNDARHWPDDVQLSFNLSAIDLSSPESASLLQAIILDSGFPPQRLMFEITETAIMQDFERALECLGLFTAMGVRIA
LDDFGTGYSSLGYLQKMPIDRLKIDRSFTLGLMTRRGTRSIMRSIVTLCKSLDIECVVEGVSNGRQAEILREMGAPYLQG
FHFSRAMSQTQLLEYLTPAAGSDCSTHDPDEDLRRMA

Sequences:

>Translated_597_residues
MSFTLSDDHFKRLFPAFIQLDLAGNIVSVGPSLERLLGPGLTGRPFFETFKVETPRRIVSAQGLNDQREVTIMIRAGKTD
LRLRGIVVRSAESICLLVGHVPDVNAEEAAFMLRMSDFSPADGSLDLLVAAHLRKGLLQDAKTLVMELQEKSAEADALAH
MDPLTAVTNRRGFFRKLEERLSIARAHNTPLTVGVIDLDGFKPVNDIFGHAAGDQLLFQSGARVREIAGPNGIVGRLGGD
EFGIILPELGDEAEILEIGQRICDALAEPFKVKEGIARIGASAGFAAFPHAGDTTETLFERADYALYHSKQQERGRPMVF
TSQHEREIRYQSSIEQGLRESADDEFQIVYQPIIRAADGKTTGVEALARWTSPLLGPIRPDIFIRAAEQNGAVSRLTRIL
LRKALNDARHWPDDVQLSFNLSAIDLSSPESASLLQAIILDSGFPPQRLMFEITETAIMQDFERALECLGLFTAMGVRIA
LDDFGTGYSSLGYLQKMPIDRLKIDRSFTLGLMTRRGTRSIMRSIVTLCKSLDIECVVEGVSNGRQAEILREMGAPYLQG
FHFSRAMSQTQLLEYLTPAAGSDCSTHDPDEDLRRMA
>Mature_596_residues
SFTLSDDHFKRLFPAFIQLDLAGNIVSVGPSLERLLGPGLTGRPFFETFKVETPRRIVSAQGLNDQREVTIMIRAGKTDL
RLRGIVVRSAESICLLVGHVPDVNAEEAAFMLRMSDFSPADGSLDLLVAAHLRKGLLQDAKTLVMELQEKSAEADALAHM
DPLTAVTNRRGFFRKLEERLSIARAHNTPLTVGVIDLDGFKPVNDIFGHAAGDQLLFQSGARVREIAGPNGIVGRLGGDE
FGIILPELGDEAEILEIGQRICDALAEPFKVKEGIARIGASAGFAAFPHAGDTTETLFERADYALYHSKQQERGRPMVFT
SQHEREIRYQSSIEQGLRESADDEFQIVYQPIIRAADGKTTGVEALARWTSPLLGPIRPDIFIRAAEQNGAVSRLTRILL
RKALNDARHWPDDVQLSFNLSAIDLSSPESASLLQAIILDSGFPPQRLMFEITETAIMQDFERALECLGLFTAMGVRIAL
DDFGTGYSSLGYLQKMPIDRLKIDRSFTLGLMTRRGTRSIMRSIVTLCKSLDIECVVEGVSNGRQAEILREMGAPYLQGF
HFSRAMSQTQLLEYLTPAAGSDCSTHDPDEDLRRMA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=414, Percent_Identity=30.6763285024155, Blast_Score=203, Evalue=3e-53,
Organism=Escherichia coli, GI87081921, Length=477, Percent_Identity=26.2054507337526, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI226510982, Length=431, Percent_Identity=27.1461716937355, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI87081743, Length=230, Percent_Identity=35.2173913043478, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788502, Length=239, Percent_Identity=32.2175732217573, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1790496, Length=234, Percent_Identity=32.4786324786325, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787055, Length=452, Percent_Identity=25, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI87081845, Length=257, Percent_Identity=30.3501945525292, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI87081980, Length=244, Percent_Identity=31.9672131147541, Blast_Score=116, Evalue=5e-27,
Organism=Escherichia coli, GI1786507, Length=244, Percent_Identity=30.7377049180328, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI87081977, Length=193, Percent_Identity=31.6062176165803, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1788381, Length=355, Percent_Identity=28.169014084507, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI1788956, Length=191, Percent_Identity=33.5078534031414, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082007, Length=199, Percent_Identity=33.1658291457286, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1787262, Length=175, Percent_Identity=32, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1787802, Length=163, Percent_Identity=31.2883435582822, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI145693134, Length=178, Percent_Identity=36.5168539325843, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI87082096, Length=193, Percent_Identity=29.5336787564767, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081881, Length=169, Percent_Identity=32.5443786982249, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1787410, Length=154, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786584, Length=180, Percent_Identity=27.7777777777778, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787816, Length=168, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1788849, Length=189, Percent_Identity=28.042328042328, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789650, Length=460, Percent_Identity=21.7391304347826, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 65889; Mature: 65758

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFTLSDDHFKRLFPAFIQLDLAGNIVSVGPSLERLLGPGLTGRPFFETFKVETPRRIVS
CCCCCCHHHHHHHHHHHHHHECCCCEEECCCHHHHHHCCCCCCCCCHHHHCCCCCHHHHH
AQGLNDQREVTIMIRAGKTDLRLRGIVVRSAESICLLVGHVPDVNAEEAAFMLRMSDFSP
HCCCCCCCEEEEEEEECCCCEEEEEEEEECCCCEEEEEECCCCCCHHHHEEEEEECCCCC
ADGSLDLLVAAHLRKGLLQDAKTLVMELQEKSAEADALAHMDPLTAVTNRRGFFRKLEER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHCCHHHHHHHHHH
LSIARAHNTPLTVGVIDLDGFKPVNDIFGHAAGDQLLFQSGARVREIAGPNGIVGRLGGD
HHHHHHCCCCEEEEEEECCCCCCHHHHHCCCCCCHHHHHCCCCEEECCCCCCEEECCCCC
EFGIILPELGDEAEILEIGQRICDALAEPFKVKEGIARIGASAGFAAFPHAGDTTETLFE
CCEEECCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
RADYALYHSKQQERGRPMVFTSQHEREIRYQSSIEQGLRESADDEFQIVYQPIIRAADGK
HHHHHHHHCCHHHCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
TTGVEALARWTSPLLGPIRPDIFIRAAEQNGAVSRLTRILLRKALNDARHWPDDVQLSFN
CHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
LSAIDLSSPESASLLQAIILDSGFPPQRLMFEITETAIMQDFERALECLGLFTAMGVRIA
EEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
LDDFGTGYSSLGYLQKMPIDRLKIDRSFTLGLMTRRGTRSIMRSIVTLCKSLDIECVVEG
EECCCCCHHHHHHHHHCCHHHHEECCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHEEHHH
VSNGRQAEILREMGAPYLQGFHFSRAMSQTQLLEYLTPAAGSDCSTHDPDEDLRRMA
HCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCC
>Mature Secondary Structure 
SFTLSDDHFKRLFPAFIQLDLAGNIVSVGPSLERLLGPGLTGRPFFETFKVETPRRIVS
CCCCCHHHHHHHHHHHHHHECCCCEEECCCHHHHHHCCCCCCCCCHHHHCCCCCHHHHH
AQGLNDQREVTIMIRAGKTDLRLRGIVVRSAESICLLVGHVPDVNAEEAAFMLRMSDFSP
HCCCCCCCEEEEEEEECCCCEEEEEEEEECCCCEEEEEECCCCCCHHHHEEEEEECCCCC
ADGSLDLLVAAHLRKGLLQDAKTLVMELQEKSAEADALAHMDPLTAVTNRRGFFRKLEER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHCCHHHHHHHHHH
LSIARAHNTPLTVGVIDLDGFKPVNDIFGHAAGDQLLFQSGARVREIAGPNGIVGRLGGD
HHHHHHCCCCEEEEEEECCCCCCHHHHHCCCCCCHHHHHCCCCEEECCCCCCEEECCCCC
EFGIILPELGDEAEILEIGQRICDALAEPFKVKEGIARIGASAGFAAFPHAGDTTETLFE
CCEEECCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
RADYALYHSKQQERGRPMVFTSQHEREIRYQSSIEQGLRESADDEFQIVYQPIIRAADGK
HHHHHHHHCCHHHCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
TTGVEALARWTSPLLGPIRPDIFIRAAEQNGAVSRLTRILLRKALNDARHWPDDVQLSFN
CHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
LSAIDLSSPESASLLQAIILDSGFPPQRLMFEITETAIMQDFERALECLGLFTAMGVRIA
EEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
LDDFGTGYSSLGYLQKMPIDRLKIDRSFTLGLMTRRGTRSIMRSIVTLCKSLDIECVVEG
EECCCCCHHHHHHHHHCCHHHHEECCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHEEHHH
VSNGRQAEILREMGAPYLQGFHFSRAMSQTQLLEYLTPAAGSDCSTHDPDEDLRRMA
HCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]