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The map label for this gene is atsA [H]

Identifier: 114798044

GI number: 114798044

Start: 2309894

End: 2311567

Strand: Direct

Name: atsA [H]

Synonym: HNE_2211

Alternate gene names: 114798044

Gene position: 2309894-2311567 (Clockwise)

Preceding gene: 114797247

Following gene: 114800456

Centisome position: 62.34

GC content: 61.23

Gene sequence:

>1674_bases
ATGCGGTGCTTTCTTGCGACACTGTTGACGTGCATGTCGGTTGGCTTGACAGCCGGCTGCGCGTCCAGCGATCCTCCCAG
CCAGCCAGAGCGCCCCAATTTCCTTGTCATTGTCGCCGATGACATGGGGTGGTCCGATCTCGGCGCCTTTGGCGGCGAGA
TCGACACCCCCAATCTGGATCAACTCGCCATGGGCGGGATCCGTCTGACGGATTTTCACACCTCGCCCACCTGCTCGCCG
ACCCGCGCCATGCTGCTGACGGGCGCGGACCACCACCGCGTCGGCCTCGGCACAATGCCAGACCTGATCACCCCGGCGCA
AAGGGGCCAGCCAGGATATGAAGGCTATCTCACTTCTGGCCTCCCCACCGTTGCTGAAACTCTGTCTGCTGAAGGCTATT
TCACCGCGATCACCGGAAAATGGCATCTCGGCAATGAGGCAAGCCAGTTGCCCGTCTCCCGGGGCTTTGATCGGTCATAT
GTCCTGTTGAATGGTTCACACAACCAATTCGGCGCAGACCAGAACGAACACTGGAAAGCGCTGGGAGAGCAGGCAGACTA
CAGGGAAGGCCTCGAAGAGGTCCAGTATCCCCTGGGCATTTACTCTTCCGATTTTTTTGCTGGCAAGCTCATCAGCTATC
TTGAAGAATCCTCCCAAAACCGTCCCTTCTTCGCATATATTGCCTACACTCAGCCCCACTGGCCCCTTCAGGCGCCTGCA
GACACGATTGCCAAATACAAAGGCCGCTATGATGCCGGACCTGAAGCTCTGCGGGCGGAACGTCTGGCGCGCCAAAAGGC
ACTGGGGCTGGTGGCCGAGGATGTTGAGCCGCACCCCTTCTTTGGCGTGAAGCCATGGGAAAGTCTGTCTGCAGAGCAGC
GCGCCATGGATGCCCGCCGCATGGAAATTTACGCGGCGATGATTGACGAGATGGATCAGAGCGTCGGCCGCATTCTCACG
GCCTTGCGTGAAAGCGGCGAACTGGACAACACAGTGATTGTATTTCTTTCCGATAACGGACCGCACGCCCGGCCGGAAGA
GGCCCCCCGCCCCAACGAACCGGGCGCAACCAGCAATCCCGACCTGATTGCAGCCCTGAATATCGACAACAGTCTGGCGT
CTCTGGGCTCTGCGCAATCCTACACCGGATATGGCCCGGGCTGGGCGCAGGCAGGCTCTGCCCCCTCGCGCCTCTTCAAG
GGTGTCACGACCCAGGGCGGCATTCGCACCACTGCGTTTGTGAACGGCCCGGGCATTCCGGGCGGCCAGATCAGTGACGC
GCTGCTGCATGTAATGGACATCACACCCACGCTGCTGGACCTTGCCAGCATACACACGCCGGACAACCCTGCTATCGAGG
GACGCAGCTGGGCGGAGCTGCTCTCAGGGGCGGCGGATCATGTCCGCGCGCCGGAAGAAACGCTCGGCTGGGAACTCTTC
TACGGCCGCGCGGTGCGCCAGGGAGACTGGAAGGCTGTCTATCTGGCAGCCCGCATGATTGGGGCGACAGAAAGCCGGTG
GGAACTCTTCAATCTCGAAGTCGATCCAGGTGAAACGCAGGATCTTTCCGCCACAGAACCTGAACGGCTCAAGACCCTCC
TGACAGAATGGGACCGCTATGCCGCCCGCAACGGGGTGGTGGTGCCGCCCCCTGCGCCCGACGGCGCAGACTGA

Upstream 100 bases:

>100_bases
GTTCGACCGTGGCGATCTCTCCGCGGGGCCGGTCGGTCCTTCTTGAACTTTCTTCAAAGTTCTAGAAACGTCAGAGGCGA
TAGTGACAAGGACAACAACC

Downstream 100 bases:

>100_bases
AGATCCAGATCCGTGCGGTTCCCTGTTGACCCGCTCCCCGTGTAGAAATGACCAAGGAGTCACTCTTGGACCGGCCCGGC
CTCGATACGAATCCACTGGA

Product: sulfatase family protein

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MRCFLATLLTCMSVGLTAGCASSDPPSQPERPNFLVIVADDMGWSDLGAFGGEIDTPNLDQLAMGGIRLTDFHTSPTCSP
TRAMLLTGADHHRVGLGTMPDLITPAQRGQPGYEGYLTSGLPTVAETLSAEGYFTAITGKWHLGNEASQLPVSRGFDRSY
VLLNGSHNQFGADQNEHWKALGEQADYREGLEEVQYPLGIYSSDFFAGKLISYLEESSQNRPFFAYIAYTQPHWPLQAPA
DTIAKYKGRYDAGPEALRAERLARQKALGLVAEDVEPHPFFGVKPWESLSAEQRAMDARRMEIYAAMIDEMDQSVGRILT
ALRESGELDNTVIVFLSDNGPHARPEEAPRPNEPGATSNPDLIAALNIDNSLASLGSAQSYTGYGPGWAQAGSAPSRLFK
GVTTQGGIRTTAFVNGPGIPGGQISDALLHVMDITPTLLDLASIHTPDNPAIEGRSWAELLSGAADHVRAPEETLGWELF
YGRAVRQGDWKAVYLAARMIGATESRWELFNLEVDPGETQDLSATEPERLKTLLTEWDRYAARNGVVVPPPAPDGAD

Sequences:

>Translated_557_residues
MRCFLATLLTCMSVGLTAGCASSDPPSQPERPNFLVIVADDMGWSDLGAFGGEIDTPNLDQLAMGGIRLTDFHTSPTCSP
TRAMLLTGADHHRVGLGTMPDLITPAQRGQPGYEGYLTSGLPTVAETLSAEGYFTAITGKWHLGNEASQLPVSRGFDRSY
VLLNGSHNQFGADQNEHWKALGEQADYREGLEEVQYPLGIYSSDFFAGKLISYLEESSQNRPFFAYIAYTQPHWPLQAPA
DTIAKYKGRYDAGPEALRAERLARQKALGLVAEDVEPHPFFGVKPWESLSAEQRAMDARRMEIYAAMIDEMDQSVGRILT
ALRESGELDNTVIVFLSDNGPHARPEEAPRPNEPGATSNPDLIAALNIDNSLASLGSAQSYTGYGPGWAQAGSAPSRLFK
GVTTQGGIRTTAFVNGPGIPGGQISDALLHVMDITPTLLDLASIHTPDNPAIEGRSWAELLSGAADHVRAPEETLGWELF
YGRAVRQGDWKAVYLAARMIGATESRWELFNLEVDPGETQDLSATEPERLKTLLTEWDRYAARNGVVVPPPAPDGAD
>Mature_557_residues
MRCFLATLLTCMSVGLTAGCASSDPPSQPERPNFLVIVADDMGWSDLGAFGGEIDTPNLDQLAMGGIRLTDFHTSPTCSP
TRAMLLTGADHHRVGLGTMPDLITPAQRGQPGYEGYLTSGLPTVAETLSAEGYFTAITGKWHLGNEASQLPVSRGFDRSY
VLLNGSHNQFGADQNEHWKALGEQADYREGLEEVQYPLGIYSSDFFAGKLISYLEESSQNRPFFAYIAYTQPHWPLQAPA
DTIAKYKGRYDAGPEALRAERLARQKALGLVAEDVEPHPFFGVKPWESLSAEQRAMDARRMEIYAAMIDEMDQSVGRILT
ALRESGELDNTVIVFLSDNGPHARPEEAPRPNEPGATSNPDLIAALNIDNSLASLGSAQSYTGYGPGWAQAGSAPSRLFK
GVTTQGGIRTTAFVNGPGIPGGQISDALLHVMDITPTLLDLASIHTPDNPAIEGRSWAELLSGAADHVRAPEETLGWELF
YGRAVRQGDWKAVYLAARMIGATESRWELFNLEVDPGETQDLSATEPERLKTLLTEWDRYAARNGVVVPPPAPDGAD

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI59797060, Length=564, Percent_Identity=28.0141843971631, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI38569405, Length=576, Percent_Identity=25.8680555555556, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI109389362, Length=569, Percent_Identity=25.1318101933216, Blast_Score=150, Evalue=4e-36,
Organism=Homo sapiens, GI38569407, Length=428, Percent_Identity=27.5700934579439, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI45430057, Length=582, Percent_Identity=29.2096219931272, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI146229331, Length=538, Percent_Identity=27.8810408921933, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI146229329, Length=538, Percent_Identity=27.8810408921933, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI6005990, Length=538, Percent_Identity=27.8810408921933, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI146229324, Length=538, Percent_Identity=27.8810408921933, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI4503899, Length=443, Percent_Identity=27.765237020316, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI53831991, Length=586, Percent_Identity=25.5972696245734, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI157266309, Length=485, Percent_Identity=26.8041237113402, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI31742482, Length=554, Percent_Identity=26.3537906137184, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI58743319, Length=330, Percent_Identity=25.1515151515152, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI71852586, Length=142, Percent_Identity=40.1408450704225, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI71852584, Length=142, Percent_Identity=40.1408450704225, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI87081924, Length=495, Percent_Identity=25.0505050505051, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790233, Length=134, Percent_Identity=37.3134328358209, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI115533416, Length=542, Percent_Identity=26.0147601476015, Blast_Score=143, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI115533418, Length=523, Percent_Identity=25.8126195028681, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17559078, Length=277, Percent_Identity=28.5198555956679, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24666109, Length=489, Percent_Identity=27.6073619631902, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281363223, Length=482, Percent_Identity=26.1410788381743, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281366397, Length=350, Percent_Identity=26.8571428571429, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI281366395, Length=350, Percent_Identity=26.8571428571429, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24666163, Length=350, Percent_Identity=26.8571428571429, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24666175, Length=442, Percent_Identity=26.6968325791855, Blast_Score=122, Evalue=9e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 60364; Mature: 60364

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00523 SULFATASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCFLATLLTCMSVGLTAGCASSDPPSQPERPNFLVIVADDMGWSDLGAFGGEIDTPNLD
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCCCCCCCHH
QLAMGGIRLTDFHTSPTCSPTRAMLLTGADHHRVGLGTMPDLITPAQRGQPGYEGYLTSG
HHHHCCEEEEECCCCCCCCCCCEEEEECCCCCEECCCCCCHHCCCHHCCCCCCCCEECCC
LPTVAETLSAEGYFTAITGKWHLGNEASQLPVSRGFDRSYVLLNGSHNQFGADQNEHWKA
CHHHHHHHCCCCEEEEEECEEECCCCHHCCCHHCCCCCEEEEEECCCCCCCCCCCHHHHH
LGEQADYREGLEEVQYPLGIYSSDFFAGKLISYLEESSQNRPFFAYIAYTQPHWPLQAPA
HCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCH
DTIAKYKGRYDAGPEALRAERLARQKALGLVAEDVEPHPFFGVKPWESLSAEQRAMDARR
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
MEIYAAMIDEMDQSVGRILTALRESGELDNTVIVFLSDNGPHARPEEAPRPNEPGATSNP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
DLIAALNIDNSLASLGSAQSYTGYGPGWAQAGSAPSRLFKGVTTQGGIRTTAFVNGPGIP
CEEEEEECCHHHHHHCCCCCCCCCCCCHHCCCCCHHHHHHCCCCCCCEEEEEEECCCCCC
GGQISDALLHVMDITPTLLDLASIHTPDNPAIEGRSWAELLSGAADHVRAPEETLGWELF
CCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHCCCHHHHCCCHHHHCEEEE
YGRAVRQGDWKAVYLAARMIGATESRWELFNLEVDPGETQDLSATEPERLKTLLTEWDRY
ECCHHCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
AARNGVVVPPPAPDGAD
HHCCCEEECCCCCCCCC
>Mature Secondary Structure
MRCFLATLLTCMSVGLTAGCASSDPPSQPERPNFLVIVADDMGWSDLGAFGGEIDTPNLD
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCCCCCCCHH
QLAMGGIRLTDFHTSPTCSPTRAMLLTGADHHRVGLGTMPDLITPAQRGQPGYEGYLTSG
HHHHCCEEEEECCCCCCCCCCCEEEEECCCCCEECCCCCCHHCCCHHCCCCCCCCEECCC
LPTVAETLSAEGYFTAITGKWHLGNEASQLPVSRGFDRSYVLLNGSHNQFGADQNEHWKA
CHHHHHHHCCCCEEEEEECEEECCCCHHCCCHHCCCCCEEEEEECCCCCCCCCCCHHHHH
LGEQADYREGLEEVQYPLGIYSSDFFAGKLISYLEESSQNRPFFAYIAYTQPHWPLQAPA
HCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCH
DTIAKYKGRYDAGPEALRAERLARQKALGLVAEDVEPHPFFGVKPWESLSAEQRAMDARR
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
MEIYAAMIDEMDQSVGRILTALRESGELDNTVIVFLSDNGPHARPEEAPRPNEPGATSNP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
DLIAALNIDNSLASLGSAQSYTGYGPGWAQAGSAPSRLFKGVTTQGGIRTTAFVNGPGIP
CEEEEEECCHHHHHHCCCCCCCCCCCCHHCCCCCHHHHHHCCCCCCCEEEEEEECCCCCC
GGQISDALLHVMDITPTLLDLASIHTPDNPAIEGRSWAELLSGAADHVRAPEETLGWELF
CCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHCCCHHHHCCCHHHHCEEEE
YGRAVRQGDWKAVYLAARMIGATESRWELFNLEVDPGETQDLSATEPERLKTLLTEWDRY
ECCHHCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
AARNGVVVPPPAPDGAD
HHCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7744061; 10984043 [H]