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The map label for this gene is ubiB [C]

Identifier: 114798029

GI number: 114798029

Start: 564778

End: 566142

Strand: Direct

Name: ubiB [C]

Synonym: HNE_0567

Alternate gene names: 114798029

Gene position: 564778-566142 (Clockwise)

Preceding gene: 114800144

Following gene: 114797063

Centisome position: 15.24

GC content: 64.1

Gene sequence:

>1365_bases
ATGAGCCAGCCCCCATCCGATACCTCCGATCCCGAACGCAACCGCCTCTCCGGGCGGATTGCCCGCACTGCCAAGGTGGG
CGCCAATCTGTCGGGCGCGGGGCTGACCTTTGCGGCCCAGTCGCTGTTTGGCGGCGACAAGGGTGACGAGCGGATCGCCA
GGGCGATGGCGGCCGCGCTGGGCAAGTCCAAAGGGCCGCTGATGAAGGTGGCGCAGATGGTCTCGACCGTGCCCGATCTG
CTGCCGCCCGAATATGCTGCCGAGTTCGCCAAGCTGCAGGCCGAGGCCCCCGCAATGGGCTGGCCCTTCGTGAAGCGCCG
GATGCGGGCGGAGCTGGGCGCGGACTGGGACGGCAAATTTGCAGACTTCGGCAAGGAAGCCAGCCACGCCGCCTCGCTTG
GCCAGGTGCATGGCGCGACCCTGCACGACGGCCGCAAGGTTGCCTGCAAGCTGCAATACCCGGACATGGCAAGCGCGGTG
GAGTCCGATATCGGCCAACTCCGGACACTTCTCGGCCTTTTCAAGCGCATGGATGGCTCGATTGATGCCGACGAGATGGT
CGCCGAGATCACCGACCGTCTGCGCGAGGAACTCGATTACGAGCGCGAGGCCAAACATATGGCGCTCTACCGGGACATGC
TCTCGGACAAGGCCTTCATCAAATGCCCTGAGCCGATAGCAGAGCTTTCGACCGCGCGGCTGATCACCATGACCTGGATG
GAGGGCGAGCGGCTCGATGCGTTCGAGACCACGCCGCAGGAAACGCGCAACCGCATTGCCGAGATGCTGTTCTGGACCTG
GTGGGCACCGATGAACTCCTATGCCGTGATCCATGGCGACCCGCATCTTGGCAATTATCAGGTGACCGGCGGCGGGGAAG
GGATCAACCTGCTGGACTTCGGCTGTGTGCGCATCTTCCCCCCTGCCTTTGTGGCCGGCGTCGTCGATCTCTACCGGGCG
ATGTTGCACGATGATTTTGACGCGGCCTATGCCGCTTATGAGGCCTGGGGCTTCCAGAACCTGTCGCGGGAGCTGGTTGA
AGTTCTGAACGTCTGGGCGCGCTTCATCTATGGCCCGATTATCGACGACCGGGTGCGCACGGTGGCCGATGGCGTGTCGG
CCGGGGAGTATGGCCGCAAGGAAGCTTTCCGCGTGCGCCAGCTGCTGAAGGAAAAAGGCCCGGTGAAGATCCCGCGCGAG
TTCGTGTTCATGGACCGCGCCGCCATTGGCCTGGGCGCGGCCTATCTGCGCCTTGGCGCGGAGCTCAATTTCCATGAGCT
GTTCGAGCAAAGTCTGGAGGGCTTCTCCGTTGAGAAGGTGACGGCGCGCCAGGCTGAGGCACTTGGACGGGCAGGCCTTG
CATGA

Upstream 100 bases:

>100_bases
GTGGCGATCTCGGGGCGGCGTATACGCCTGCATGAACACTTTGTCACCCCGCCCGCCTGCAGCCTGTCCAAGGCGGCGGG
GCAGGCCTATATCCTCCGGC

Downstream 100 bases:

>100_bases
AGCCCCCAGCCTGGATGCCGACACTCTCGATCGCCTCGATCCGCGAGGTTGGTCCTATAGCTGTTCTTGGGATTATTGCG
CTCTGCCTTCTGGGCTTTGC

Product: ABC1 family protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MSQPPSDTSDPERNRLSGRIARTAKVGANLSGAGLTFAAQSLFGGDKGDERIARAMAAALGKSKGPLMKVAQMVSTVPDL
LPPEYAAEFAKLQAEAPAMGWPFVKRRMRAELGADWDGKFADFGKEASHAASLGQVHGATLHDGRKVACKLQYPDMASAV
ESDIGQLRTLLGLFKRMDGSIDADEMVAEITDRLREELDYEREAKHMALYRDMLSDKAFIKCPEPIAELSTARLITMTWM
EGERLDAFETTPQETRNRIAEMLFWTWWAPMNSYAVIHGDPHLGNYQVTGGGEGINLLDFGCVRIFPPAFVAGVVDLYRA
MLHDDFDAAYAAYEAWGFQNLSRELVEVLNVWARFIYGPIIDDRVRTVADGVSAGEYGRKEAFRVRQLLKEKGPVKIPRE
FVFMDRAAIGLGAAYLRLGAELNFHELFEQSLEGFSVEKVTARQAEALGRAGLA

Sequences:

>Translated_454_residues
MSQPPSDTSDPERNRLSGRIARTAKVGANLSGAGLTFAAQSLFGGDKGDERIARAMAAALGKSKGPLMKVAQMVSTVPDL
LPPEYAAEFAKLQAEAPAMGWPFVKRRMRAELGADWDGKFADFGKEASHAASLGQVHGATLHDGRKVACKLQYPDMASAV
ESDIGQLRTLLGLFKRMDGSIDADEMVAEITDRLREELDYEREAKHMALYRDMLSDKAFIKCPEPIAELSTARLITMTWM
EGERLDAFETTPQETRNRIAEMLFWTWWAPMNSYAVIHGDPHLGNYQVTGGGEGINLLDFGCVRIFPPAFVAGVVDLYRA
MLHDDFDAAYAAYEAWGFQNLSRELVEVLNVWARFIYGPIIDDRVRTVADGVSAGEYGRKEAFRVRQLLKEKGPVKIPRE
FVFMDRAAIGLGAAYLRLGAELNFHELFEQSLEGFSVEKVTARQAEALGRAGLA
>Mature_453_residues
SQPPSDTSDPERNRLSGRIARTAKVGANLSGAGLTFAAQSLFGGDKGDERIARAMAAALGKSKGPLMKVAQMVSTVPDLL
PPEYAAEFAKLQAEAPAMGWPFVKRRMRAELGADWDGKFADFGKEASHAASLGQVHGATLHDGRKVACKLQYPDMASAVE
SDIGQLRTLLGLFKRMDGSIDADEMVAEITDRLREELDYEREAKHMALYRDMLSDKAFIKCPEPIAELSTARLITMTWME
GERLDAFETTPQETRNRIAEMLFWTWWAPMNSYAVIHGDPHLGNYQVTGGGEGINLLDFGCVRIFPPAFVAGVVDLYRAM
LHDDFDAAYAAYEAWGFQNLSRELVEVLNVWARFIYGPIIDDRVRTVADGVSAGEYGRKEAFRVRQLLKEKGPVKIPREF
VFMDRAAIGLGAAYLRLGAELNFHELFEQSLEGFSVEKVTARQAEALGRAGLA

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI27363457, Length=310, Percent_Identity=28.0645161290323, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI34147522, Length=281, Percent_Identity=29.1814946619217, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI217416386, Length=249, Percent_Identity=28.9156626506024, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI40254938, Length=322, Percent_Identity=27.9503105590062, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI41393593, Length=325, Percent_Identity=28.6153846153846, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI217035081, Length=222, Percent_Identity=29.7297297297297, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI2367309, Length=233, Percent_Identity=26.1802575107296, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI32565180, Length=311, Percent_Identity=30.8681672025724, Blast_Score=138, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17559152, Length=294, Percent_Identity=27.5510204081633, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6321319, Length=318, Percent_Identity=30.5031446540881, Blast_Score=149, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6323282, Length=323, Percent_Identity=24.7678018575851, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI18859849, Length=260, Percent_Identity=29.6153846153846, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI22024280, Length=305, Percent_Identity=24.9180327868852, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24662575, Length=291, Percent_Identity=24.7422680412371, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 50152; Mature: 50021

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPPSDTSDPERNRLSGRIARTAKVGANLSGAGLTFAAQSLFGGDKGDERIARAMAAAL
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
GKSKGPLMKVAQMVSTVPDLLPPEYAAEFAKLQAEAPAMGWPFVKRRMRAELGADWDGKF
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCH
ADFGKEASHAASLGQVHGATLHDGRKVACKLQYPDMASAVESDIGQLRTLLGLFKRMDGS
HHHCCHHHHHHHHHHHCCCEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC
IDADEMVAEITDRLREELDYEREAKHMALYRDMLSDKAFIKCPEPIAELSTARLITMTWM
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHEEEEEEC
EGERLDAFETTPQETRNRIAEMLFWTWWAPMNSYAVIHGDPHLGNYQVTGGGEGINLLDF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCCCCCCHHHH
GCVRIFPPAFVAGVVDLYRAMLHDDFDAAYAAYEAWGFQNLSRELVEVLNVWARFIYGPI
HHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCH
IDDRVRTVADGVSAGEYGRKEAFRVRQLLKEKGPVKIPREFVFMDRAAIGLGAAYLRLGA
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
ELNFHELFEQSLEGFSVEKVTARQAEALGRAGLA
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SQPPSDTSDPERNRLSGRIARTAKVGANLSGAGLTFAAQSLFGGDKGDERIARAMAAAL
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
GKSKGPLMKVAQMVSTVPDLLPPEYAAEFAKLQAEAPAMGWPFVKRRMRAELGADWDGKF
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCH
ADFGKEASHAASLGQVHGATLHDGRKVACKLQYPDMASAVESDIGQLRTLLGLFKRMDGS
HHHCCHHHHHHHHHHHCCCEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC
IDADEMVAEITDRLREELDYEREAKHMALYRDMLSDKAFIKCPEPIAELSTARLITMTWM
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHEEEEEEC
EGERLDAFETTPQETRNRIAEMLFWTWWAPMNSYAVIHGDPHLGNYQVTGGGEGINLLDF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCCCCCCHHHH
GCVRIFPPAFVAGVVDLYRAMLHDDFDAAYAAYEAWGFQNLSRELVEVLNVWARFIYGPI
HHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCH
IDDRVRTVADGVSAGEYGRKEAFRVRQLLKEKGPVKIPREFVFMDRAAIGLGAAYLRLGA
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
ELNFHELFEQSLEGFSVEKVTARQAEALGRAGLA
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA