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The map label for this gene is rhbB [H]

Identifier: 114797799

GI number: 114797799

Start: 611834

End: 613318

Strand: Direct

Name: rhbB [H]

Synonym: HNE_0613

Alternate gene names: 114797799

Gene position: 611834-613318 (Clockwise)

Preceding gene: 114799918

Following gene: 114798723

Centisome position: 16.51

GC content: 65.45

Gene sequence:

>1485_bases
ATGACCGATCCCAAACCGCCCGTCCCCCAGCCAGGGCTCGACCCCCAGGATTGGGCAGCCTTCCGCCAGACGGCGCATGA
CCTGCTCGACGCCGCGATCGACAAGATGACCGCCAACCGCGAAGGCCGCGTCTGGACCCCGTTCCCGGCCGAGATGAAAG
CCGCCTTTGCCCGGCCTCTCCCAAAGGAAGGGCAGGGAGAGGCAGACCTCGCCGCCCAGCTCGCCGCACTGCTGCCCTAT
GGGGTGGGCAACACTCATCCGCGCTTCTTCGGCTGGGTGCATGGCTCGGGCACGCCGCAGAACATGCTGGCCGAGATTGT
CGCCAGCGCGATCAACGCGAACGCCGGCGGGCGCGATCACGGCGCCATCTATGTTGAGCGCCAGGTCATTGCCTGGTGCC
GCGAGATGTTCGGCTTCCCCGAAACCGCCAGCGGCCTCCTCGTCTCGGGCACCTCGCTCGCCACCGTCATCGCCGTGAAA
GCCGCGCGCGATGCGCGCCTCGAATTCCGCAGCCGCAAGGAAGGCATCTGCGGAGACCGTCTCGTGGGCTATGCCTCGGC
CGAGGCCCATGCCTGCAACCCCCGCGCCTTCGACATTCTCGGCCTGGGTACAGATGCCCTGCGCCGTATCCCCGTGAACG
ACGCCTATGAGATGGACACGGCCGCCCTGCGCGCCGCCATCCAGGCAGACCGCGAAGCCGGCCTCACGCCTTTCCTGGTC
ATCGGCACAGCGGGCACCGTCAATACCGGCTCAACCGATCCGCTGGCGGAGCTTTCAGCCATTGCGAAAGAAGAAAACCT
CTGGTTCCATGTCGACGGCGCCTTCGGGGCGCTCGCCCGCCTCTCGCCCGCCCATGCCGAACGCTTCAAGGCTATCGAGC
AGGCTGATTCGGTCGCCTTCGATTTCCATAAATGGCTGCATGTGAACTATGATGCCGGCTGCGTCCTCATCCGCGATGGG
GCCCACCATCGCCATGCCTTCTCGGACCGTCCGGATTATCTCAAGGGCGCCGAGCGCGGCATTGCGGCGGGCAATCCCTG
GCCGGTGGAATATGGCCCGGAGCTGTCGCGCGGCTTCCGTGCCCTGAAGGTCTGGTCCCAGATCGCCGGTTTTGGCACGG
CAAAGCTCGGAGAAGCCATCGCCCGCAACTGCGATCAGGCCGCCTATCTCTCCGCAAAGGTCGCCGCCGATACGCGCTTC
GATCTCCTCGCCCCGGCAAAGCTCAACATCTGCTGCTTCCGCTACCGCGCCGACGGGCTGGACGAGGCCGCGCTGGACGC
GCTGAACGAGGAAATCGTCATCCGCCTTCAGGAAAGCGGCATCGCCGCGCCATCAACCACCAAGCTGAAAGGCCGCGTTG
CCATCCGCATAAACCTCACCAATCACCGCACGCAGCACAGCGATCTCGATCTTCTGCTCACGGAGATTGTAAAGCTGGGT
GAAGATGGGGATGTCAGGGCGTCCCTCATTCCCCCGCGTCCATAG

Upstream 100 bases:

>100_bases
GCCATGCCCCGAGGGAATCGCACCCGTCAGCGCGCCCATGGATTGCGCGCATCCTCCGGGCGAGTCAGTAAGCAGCCAGA
ATTCAAAGGCTTGCCCTCCC

Downstream 100 bases:

>100_bases
CCAGAATAATCTGCGCATAGCCTGTCGCCAGCCGTCCCATATTCTCCACGGCAAGGCGTTCATTGGTGCCGTGGAAACCG
GTGAGGTCTTCGGGCGACAT

Product: decarboxylase, group II

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MTDPKPPVPQPGLDPQDWAAFRQTAHDLLDAAIDKMTANREGRVWTPFPAEMKAAFARPLPKEGQGEADLAAQLAALLPY
GVGNTHPRFFGWVHGSGTPQNMLAEIVASAINANAGGRDHGAIYVERQVIAWCREMFGFPETASGLLVSGTSLATVIAVK
AARDARLEFRSRKEGICGDRLVGYASAEAHACNPRAFDILGLGTDALRRIPVNDAYEMDTAALRAAIQADREAGLTPFLV
IGTAGTVNTGSTDPLAELSAIAKEENLWFHVDGAFGALARLSPAHAERFKAIEQADSVAFDFHKWLHVNYDAGCVLIRDG
AHHRHAFSDRPDYLKGAERGIAAGNPWPVEYGPELSRGFRALKVWSQIAGFGTAKLGEAIARNCDQAAYLSAKVAADTRF
DLLAPAKLNICCFRYRADGLDEAALDALNEEIVIRLQESGIAAPSTTKLKGRVAIRINLTNHRTQHSDLDLLLTEIVKLG
EDGDVRASLIPPRP

Sequences:

>Translated_494_residues
MTDPKPPVPQPGLDPQDWAAFRQTAHDLLDAAIDKMTANREGRVWTPFPAEMKAAFARPLPKEGQGEADLAAQLAALLPY
GVGNTHPRFFGWVHGSGTPQNMLAEIVASAINANAGGRDHGAIYVERQVIAWCREMFGFPETASGLLVSGTSLATVIAVK
AARDARLEFRSRKEGICGDRLVGYASAEAHACNPRAFDILGLGTDALRRIPVNDAYEMDTAALRAAIQADREAGLTPFLV
IGTAGTVNTGSTDPLAELSAIAKEENLWFHVDGAFGALARLSPAHAERFKAIEQADSVAFDFHKWLHVNYDAGCVLIRDG
AHHRHAFSDRPDYLKGAERGIAAGNPWPVEYGPELSRGFRALKVWSQIAGFGTAKLGEAIARNCDQAAYLSAKVAADTRF
DLLAPAKLNICCFRYRADGLDEAALDALNEEIVIRLQESGIAAPSTTKLKGRVAIRINLTNHRTQHSDLDLLLTEIVKLG
EDGDVRASLIPPRP
>Mature_493_residues
TDPKPPVPQPGLDPQDWAAFRQTAHDLLDAAIDKMTANREGRVWTPFPAEMKAAFARPLPKEGQGEADLAAQLAALLPYG
VGNTHPRFFGWVHGSGTPQNMLAEIVASAINANAGGRDHGAIYVERQVIAWCREMFGFPETASGLLVSGTSLATVIAVKA
ARDARLEFRSRKEGICGDRLVGYASAEAHACNPRAFDILGLGTDALRRIPVNDAYEMDTAALRAAIQADREAGLTPFLVI
GTAGTVNTGSTDPLAELSAIAKEENLWFHVDGAFGALARLSPAHAERFKAIEQADSVAFDFHKWLHVNYDAGCVLIRDGA
HHRHAFSDRPDYLKGAERGIAAGNPWPVEYGPELSRGFRALKVWSQIAGFGTAKLGEAIARNCDQAAYLSAKVAADTRFD
LLAPAKLNICCFRYRADGLDEAALDALNEEIVIRLQESGIAAPSTTKLKGRVAIRINLTNHRTQHSDLDLLLTEIVKLGE
DGDVRASLIPPRP

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI92110055, Length=476, Percent_Identity=26.6806722689076, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI4503281, Length=441, Percent_Identity=27.891156462585, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI132814448, Length=441, Percent_Identity=27.891156462585, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI197383062, Length=456, Percent_Identity=26.3157894736842, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI197276620, Length=482, Percent_Identity=23.6514522821577, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI4503875, Length=482, Percent_Identity=23.6514522821577, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI194294551, Length=483, Percent_Identity=25.0517598343685, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI58331246, Length=425, Percent_Identity=25.6470588235294, Blast_Score=129, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17534817, Length=471, Percent_Identity=26.7515923566879, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17534819, Length=471, Percent_Identity=26.7515923566879, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17555682, Length=453, Percent_Identity=28.0353200883002, Blast_Score=151, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI71993062, Length=425, Percent_Identity=28.9411764705882, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI71993058, Length=364, Percent_Identity=27.1978021978022, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI133931025, Length=479, Percent_Identity=24.0083507306889, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71981211, Length=454, Percent_Identity=24.2290748898678, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71981217, Length=309, Percent_Identity=26.537216828479, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17551992, Length=414, Percent_Identity=23.1884057971014, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24652373, Length=471, Percent_Identity=29.0870488322718, Blast_Score=182, Evalue=6e-46,
Organism=Drosophila melanogaster, GI24585139, Length=478, Percent_Identity=27.6150627615063, Blast_Score=162, Evalue=5e-40,
Organism=Drosophila melanogaster, GI221476190, Length=478, Percent_Identity=27.6150627615063, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24585143, Length=478, Percent_Identity=27.6150627615063, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI28573972, Length=502, Percent_Identity=26.6932270916335, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI17136594, Length=488, Percent_Identity=26.6393442622951, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24585135, Length=497, Percent_Identity=25.9557344064386, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI17136190, Length=494, Percent_Identity=24.6963562753036, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24586044, Length=486, Percent_Identity=24.8971193415638, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24657193, Length=486, Percent_Identity=24.8971193415638, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24657185, Length=486, Percent_Identity=24.8971193415638, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24657188, Length=486, Percent_Identity=24.8971193415638, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21356415, Length=438, Percent_Identity=24.6575342465753, Blast_Score=92, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 53335; Mature: 53204

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00392 DDC_GAD_HDC_YDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPKPPVPQPGLDPQDWAAFRQTAHDLLDAAIDKMTANREGRVWTPFPAEMKAAFARPL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHCCC
PKEGQGEADLAAQLAALLPYGVGNTHPRFFGWVHGSGTPQNMLAEIVASAINANAGGRDH
CCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCC
GAIYVERQVIAWCREMFGFPETASGLLVSGTSLATVIAVKAARDARLEFRSRKEGICGDR
CEEEEHHHHHHHHHHHCCCCCCCCCEEEECCHHEEHHHHHHHHHHHHHHHHHCCCCCCCH
LVGYASAEAHACNPRAFDILGLGTDALRRIPVNDAYEMDTAALRAAIQADREAGLTPFLV
HEEECCCCCCCCCCCCEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
IGTAGTVNTGSTDPLAELSAIAKEENLWFHVDGAFGALARLSPAHAERFKAIEQADSVAF
EECCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHE
DFHKWLHVNYDAGCVLIRDGAHHRHAFSDRPDYLKGAERGIAAGNPWPVEYGPELSRGFR
EEEHEEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
ALKVWSQIAGFGTAKLGEAIARNCDQAAYLSAKVAADTRFDLLAPAKLNICCFRYRADGL
HHHHHHHHHCCCHHHHHHHHHHCCCHHHHHEEECCCCCCEEEECCCEEEEEEEEECCCCC
DEAALDALNEEIVIRLQESGIAAPSTTKLKGRVAIRINLTNHRTQHSDLDLLLTEIVKLG
CHHHHHHCCCEEEEEECCCCCCCCCCCEECEEEEEEEEECCCCCCCCHHHHHHHHHHHCC
EDGDVRASLIPPRP
CCCCEEEECCCCCC
>Mature Secondary Structure 
TDPKPPVPQPGLDPQDWAAFRQTAHDLLDAAIDKMTANREGRVWTPFPAEMKAAFARPL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHCCC
PKEGQGEADLAAQLAALLPYGVGNTHPRFFGWVHGSGTPQNMLAEIVASAINANAGGRDH
CCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCC
GAIYVERQVIAWCREMFGFPETASGLLVSGTSLATVIAVKAARDARLEFRSRKEGICGDR
CEEEEHHHHHHHHHHHCCCCCCCCCEEEECCHHEEHHHHHHHHHHHHHHHHHCCCCCCCH
LVGYASAEAHACNPRAFDILGLGTDALRRIPVNDAYEMDTAALRAAIQADREAGLTPFLV
HEEECCCCCCCCCCCCEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
IGTAGTVNTGSTDPLAELSAIAKEENLWFHVDGAFGALARLSPAHAERFKAIEQADSVAF
EECCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHE
DFHKWLHVNYDAGCVLIRDGAHHRHAFSDRPDYLKGAERGIAAGNPWPVEYGPELSRGFR
EEEHEEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
ALKVWSQIAGFGTAKLGEAIARNCDQAAYLSAKVAADTRFDLLAPAKLNICCFRYRADGL
HHHHHHHHHCCCHHHHHHHHHHCCCHHHHHEEECCCCCCEEEECCCEEEEEEEEECCCCC
DEAALDALNEEIVIRLQESGIAAPSTTKLKGRVAIRINLTNHRTQHSDLDLLLTEIVKLG
CHHHHHHCCCEEEEEECCCCCCCCCCCEECEEEEEEEEECCCCCCCCHHHHHHHHHHHCC
EDGDVRASLIPPRP
CCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11274118; 11481432 [H]