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The map label for this gene is siaT [H]

Identifier: 114797782

GI number: 114797782

Start: 908840

End: 910423

Strand: Reverse

Name: siaT [H]

Synonym: HNE_0890

Alternate gene names: 114797782

Gene position: 910423-908840 (Counterclockwise)

Preceding gene: 114798395

Following gene: 114798381

Centisome position: 24.57

GC content: 65.03

Gene sequence:

>1584_bases
ATGGAGCTTGAGGCGATCCTTGCCATCTCGATGTTCATTTTTGCCATCGGCGCGCTGCTGGCAGGCTATCCCGTTGCGCT
GACCCTGGGCGGGGTGGCGCTGATCTTTGCCCTGATCGGCATTGCGACGGGCGTGTTTCCCGAGAGCTTCCTGAAAGCGT
TTCCAAGCCGCATCGAAGGCAGCTCGATCATGCAGAGCCAGACGCTGCTGGCCGTGCCGCTATTTGTCATCATGGGGGTG
ATCCTCGAGCGCTCGCGGGTGGCTGAAGACCTTCTCAATATTGCCAGCCGCCTCTTGGGCAAGGTGCGCGGCGGGCTCGG
CTTTGCGGTGGTGCTGGTGGGCACGCTGCTGGCGGCCTCGACCGGGATTGTCGGTGCGACGGTGATCACGATGACGCTGA
TCGCCCTGCCCTCAATGATCCGCCAGGGATACGACCCACGCCTCGCCACGGGCACAATTGCCGCCTCAGGAACGCTGGGC
CAGATCATTCCGCCCTCCATTGTGCTCATCCTTCTGGCCGACGCGATTTCCAATGCGGCGAGCCAGGCTTCGCTGCGCAC
GGGCGGGGGCTCGGCGGTCGTTTCGGTCGGCGACCTCTTTGCCGGAGCCTTGATTCCGGGGCTGATCCTCGTGGCGCTCT
ACATGCTGTGGATCGCTGCGATGGCGATCTTCCGGCCTTCGTCCTGCCCGCCGGCGACGGTCATCGAAGGCACAGCGCCG
CTGACCATGCGCGATGTGGCGCTGGGCCTCGGCGCGCCGCTGGCGCTGATCGTGGCGGTGCTGGGCTCGATCCTGGGCGG
CATTGCCCCGCCGACCGAAGCCGCCGCCATCGGCGCAGGCGGGGCGATCCTGCTGGCGGGGATGCGGCTGGCGCGCGAGG
CGCAGAGCCGGCTCATGCCGGTGATGCTGGCGGGCCTTGCCGGGCTGATCCTCATCATCGTGCTGCGCAACACGCTGGAC
CTGCGCACCGCGTCCAGCGGCCATAGCGGAGCAGACTTCATCGGCATGGCGATCACGGGACTTGGCGCCTTTGCCTTCTT
TGCCGCCCTGATCTCCGGGCTGCTGGTGCTGCGCCGCGTGAGGGAGTTGACGCCAGCGCTGAAAAGCTCCGCGCATATCA
CCTCCATGGTGTTCCTGATCCTGATCGGCGCGTCTCTCTTCAGCCTCGTCTTCCGGGGCTTTGACGGGGACGATCTGGTG
GCTGAGCTGCTCCATTCCGTACCCGGCGGAAAATGGGGCGCGCTGGGCATGGCGATGCTCGTGATGTTCGTGCTCGGCTT
CTTCCTCGACTTTATCGAGATCGTGTTTGTGGTGGTGCCGCTGGTGGCCCCGCCGCTGATCATGCTGGGGTTTGATCCGG
TGTGGCTCGGCATTCTGATGGCGATCAACCTGCAGACGAGCTTCCTGACGCCGCCCTTTGGCTTTGCGCTATTCTATCTG
CGCGGCGCGGCGCCGCCGGAAGTTTCCACGATGCAGATCTGGCGGGGGGCTGTGCCGTTTATTGGACTGCAGCTGATTCT
GCTGGCAATGATCGCGGCGATTCCGGGGCTGGCAACTTGGTTGCCGGCACTGGCCGCGAAATAA

Upstream 100 bases:

>100_bases
ATGGCGCAGGGGCTTTCCGAAGCGATCAAGGCCGCCCTGCGCATCACCGGCGCACTACCGCCGGAGACGCCACAGCAGCT
GGCAGCGGAGGGAGGCGGCC

Downstream 100 bases:

>100_bases
TCAAGAACAGGGTTCCAGATGGGACAGGATATTGCGCCGTTTCAGGCGATCTCGATCAGCCGCCGCGCGCATGAGCTCAA
AGCCGCTGGCCAGCGCATTC

Product: TRAP dicarboxylate transporter, DctM subunit

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MELEAILAISMFIFAIGALLAGYPVALTLGGVALIFALIGIATGVFPESFLKAFPSRIEGSSIMQSQTLLAVPLFVIMGV
ILERSRVAEDLLNIASRLLGKVRGGLGFAVVLVGTLLAASTGIVGATVITMTLIALPSMIRQGYDPRLATGTIAASGTLG
QIIPPSIVLILLADAISNAASQASLRTGGGSAVVSVGDLFAGALIPGLILVALYMLWIAAMAIFRPSSCPPATVIEGTAP
LTMRDVALGLGAPLALIVAVLGSILGGIAPPTEAAAIGAGGAILLAGMRLAREAQSRLMPVMLAGLAGLILIIVLRNTLD
LRTASSGHSGADFIGMAITGLGAFAFFAALISGLLVLRRVRELTPALKSSAHITSMVFLILIGASLFSLVFRGFDGDDLV
AELLHSVPGGKWGALGMAMLVMFVLGFFLDFIEIVFVVVPLVAPPLIMLGFDPVWLGILMAINLQTSFLTPPFGFALFYL
RGAAPPEVSTMQIWRGAVPFIGLQLILLAMIAAIPGLATWLPALAAK

Sequences:

>Translated_527_residues
MELEAILAISMFIFAIGALLAGYPVALTLGGVALIFALIGIATGVFPESFLKAFPSRIEGSSIMQSQTLLAVPLFVIMGV
ILERSRVAEDLLNIASRLLGKVRGGLGFAVVLVGTLLAASTGIVGATVITMTLIALPSMIRQGYDPRLATGTIAASGTLG
QIIPPSIVLILLADAISNAASQASLRTGGGSAVVSVGDLFAGALIPGLILVALYMLWIAAMAIFRPSSCPPATVIEGTAP
LTMRDVALGLGAPLALIVAVLGSILGGIAPPTEAAAIGAGGAILLAGMRLAREAQSRLMPVMLAGLAGLILIIVLRNTLD
LRTASSGHSGADFIGMAITGLGAFAFFAALISGLLVLRRVRELTPALKSSAHITSMVFLILIGASLFSLVFRGFDGDDLV
AELLHSVPGGKWGALGMAMLVMFVLGFFLDFIEIVFVVVPLVAPPLIMLGFDPVWLGILMAINLQTSFLTPPFGFALFYL
RGAAPPEVSTMQIWRGAVPFIGLQLILLAMIAAIPGLATWLPALAAK
>Mature_527_residues
MELEAILAISMFIFAIGALLAGYPVALTLGGVALIFALIGIATGVFPESFLKAFPSRIEGSSIMQSQTLLAVPLFVIMGV
ILERSRVAEDLLNIASRLLGKVRGGLGFAVVLVGTLLAASTGIVGATVITMTLIALPSMIRQGYDPRLATGTIAASGTLG
QIIPPSIVLILLADAISNAASQASLRTGGGSAVVSVGDLFAGALIPGLILVALYMLWIAAMAIFRPSSCPPATVIEGTAP
LTMRDVALGLGAPLALIVAVLGSILGGIAPPTEAAAIGAGGAILLAGMRLAREAQSRLMPVMLAGLAGLILIIVLRNTLD
LRTASSGHSGADFIGMAITGLGAFAFFAALISGLLVLRRVRELTPALKSSAHITSMVFLILIGASLFSLVFRGFDGDDLV
AELLHSVPGGKWGALGMAMLVMFVLGFFLDFIEIVFVVVPLVAPPLIMLGFDPVWLGILMAINLQTSFLTPPFGFALFYL
RGAAPPEVSTMQIWRGAVPFIGLQLILLAMIAAIPGLATWLPALAAK

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG4664

COG function: function code Q; TRAP-type mannitol/chloroaromatic compound transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 54337; Mature: 54337

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELEAILAISMFIFAIGALLAGYPVALTLGGVALIFALIGIATGVFPESFLKAFPSRIEG
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
SSIMQSQTLLAVPLFVIMGVILERSRVAEDLLNIASRLLGKVRGGLGFAVVLVGTLLAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TGIVGATVITMTLIALPSMIRQGYDPRLATGTIAASGTLGQIIPPSIVLILLADAISNAA
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHH
SQASLRTGGGSAVVSVGDLFAGALIPGLILVALYMLWIAAMAIFRPSSCPPATVIEGTAP
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCC
LTMRDVALGLGAPLALIVAVLGSILGGIAPPTEAAAIGAGGAILLAGMRLAREAQSRLMP
CHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
VMLAGLAGLILIIVLRNTLDLRTASSGHSGADFIGMAITGLGAFAFFAALISGLLVLRRV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RELTPALKSSAHITSMVFLILIGASLFSLVFRGFDGDDLVAELLHSVPGGKWGALGMAML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
VMFVLGFFLDFIEIVFVVVPLVAPPLIMLGFDPVWLGILMAINLQTSFLTPPFGFALFYL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCHHHCCCCHHHHHHHH
RGAAPPEVSTMQIWRGAVPFIGLQLILLAMIAAIPGLATWLPALAAK
HCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCC
>Mature Secondary Structure
MELEAILAISMFIFAIGALLAGYPVALTLGGVALIFALIGIATGVFPESFLKAFPSRIEG
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
SSIMQSQTLLAVPLFVIMGVILERSRVAEDLLNIASRLLGKVRGGLGFAVVLVGTLLAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TGIVGATVITMTLIALPSMIRQGYDPRLATGTIAASGTLGQIIPPSIVLILLADAISNAA
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHH
SQASLRTGGGSAVVSVGDLFAGALIPGLILVALYMLWIAAMAIFRPSSCPPATVIEGTAP
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCC
LTMRDVALGLGAPLALIVAVLGSILGGIAPPTEAAAIGAGGAILLAGMRLAREAQSRLMP
CHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
VMLAGLAGLILIIVLRNTLDLRTASSGHSGADFIGMAITGLGAFAFFAALISGLLVLRRV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RELTPALKSSAHITSMVFLILIGASLFSLVFRGFDGDDLVAELLHSVPGGKWGALGMAML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
VMFVLGFFLDFIEIVFVVVPLVAPPLIMLGFDPVWLGILMAINLQTSFLTPPFGFALFYL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCHHHCCCCHHHHHHHH
RGAAPPEVSTMQIWRGAVPFIGLQLILLAMIAAIPGLATWLPALAAK
HCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]