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The map label for this gene is flhA [H]

Identifier: 114797604

GI number: 114797604

Start: 258263

End: 260341

Strand: Direct

Name: flhA [H]

Synonym: HNE_0273

Alternate gene names: 114797604

Gene position: 258263-260341 (Clockwise)

Preceding gene: 114797953

Following gene: 114799957

Centisome position: 6.97

GC content: 61.18

Gene sequence:

>2079_bases
ATGCCGATGCAGAGCCTTTTGAACTTCACCAAGCCGACGGCGCTTCTGGCCATCGGCCTTATGGCCATTATCCTTGTGAT
GGTGCTGCCTATGCCGGCCTGGGTGCTGGATGTCGGGCTGACCCTTTCCTTTGCGCTCTCGATCCTGATCTTCACCACCG
TGATCTTCGTGGAGAAGCCGCTGGATTTCTCGTCCTTCCCGTCGATCCTTCTGGCCTCGCTTGTGCTGCGCCTGGCGCTG
AACGTTTCCTCCACCAAGCTGATCATCGGGGAAGGGCATACCGGCACGGACGCTGCCGGCGGGGTGATCGAGGGCTTCGC
CATGTTCATCATGGGCGGCAATCTCTTCGTCGGTCTTGTCGTGTTTGGCGTTCTGGTGATCGTGAACTTCATGGTCATCA
CGAAAGGCGCCGGCCGGATGGCCGAAGTCGGCGCGCGCTTCGCCCTGGACGCGATGCCGGGCAAGCAGCTCGCCATCGAC
TCTGATCTGGCGGTGGGCGCGATCACACATGAAGAAGCCAAGCTGCGCCGGCAGCGGGAACAGGAAGAAGCCGGTTTCCT
CGGCTCGCTGGATGGTGCCTCGAAATTCGTGAAGGGCGACGCGATCGCCGGCCTTCTGATCACGGCGCTGAACCTGATTG
CCGGGATTGGCTTTGGCGTGGTTGCGCACCAGCTGAGCGTGGTTGAAGCGCTGAACAATTATTCCATCCTGACGGTGGGA
GACGGTCTCGTCTCCCAGATCCCGGCTGTGATCGTGTCTGTTGCCGCCGCGCTTCTTCTGTCCAAGGGCCGCGAAGAAGG
CGCCATCGACCGGGCGCTCGGCCTTCAGCTCGCGGGCAATTCGACCGCGCTCTACATCGTGGCGGGTATTCTCGCCATCT
TCGCGTTGCTGCCGGGCCTGCCGTTCCTTCCCTTCATTGCGGGCGCTGCGGGCTTTGCTGCCGTGGCTTACTTCACCAAG
AAAGCTGCCGACGAGAAAGCCGCCTCAGAGGAGACCAAGCCCGAAGACGCGGCGCCCAAGGCGCCCAAGATCGGCGACTC
GATCTATGCGGACGAAATCCATCTCGAAGTGGCGCCTGATCTCGTCAATATGGTGCTGGTCGGGGAGAACGGGTTTGAGA
GCCGGATCGACAAGATCCGCCGTTATATCGCCGAAGAGTATGGGTTCGTGCTGCCGCCGATCCGTATGACGGACAACCCG
ACGCTGAAGAAGAATGAATACCGCATGCGGATTCAGGGCGTGCGGGTGGATTCCGGTATCCTGCGTCCGGGTCAGGTTCT
GGCCCTGATCGAGGAGAACCAGCTGCCCCATCTGGCAGGCGAGAAAGTGCGCGAGCCGGTCTACAAGGCAGCCGCCCGCT
GGCTGCCGTCGGCCAAGAAGCAGGAACTGGCTGCGGCCGCTGTGCCCGTGGTTGAGCCCATCGAAGTGCTTGCGACGCAT
ATGCTAGAAGTCATCCAGTCAAACTTCTCGCTGGTCTTCACCCGGATGGTGATGATGGAGACGCTAGACGCACTGGCGGC
GATTTCCGACGTTGACCGCGCCAGCGCCAACAAGCGCTTCCTAGATGAGTACATTCCTGGCAAGGTGACACCGGAGCTTC
TGCTGTCCGTCCTGCGCATGCTGCTGACCGAGCGGGTTCCGATCCGCAATCTCTTCCTGATCATCGAGACCGTGGCCGAG
GCCAAGCCGCAGGCATTGCCGCTTCCGCGGGTGATCGAACTGGTGCGTCAGCGTCTGGCATTCCAGATCGTAGACCGGCT
GCAGGACGATCAGGGCCGCCTGCCGCTGATCCAGCTGTCGACCAGTTGGGAGCAGAAGTTCACCGAGTATGAAGTGACCA
ATGAAAGCGGCGGATCGGATATTGCTCTGCCGCCGGAAATATTCGGAGAGCTGATCAATTCGGTTCAGGCGAAACTCAAT
GAGACGGCCCAGAAGGGCATCATCGCGGCTGTGGCAACCTCGTCGCGCCGGCGGCGGTTCCTGCAGACCGTGCTGGCCAG
CAAGGGCATCCGCAACGCTGTCGTCGCCTATGAAGAGATCAACTCCAAGAGCAAGCCCTACATCATCGGCGTGGCCTGA

Upstream 100 bases:

>100_bases
CATCATCGTTTTCTTCCTTTCGCTCGGTTACATGACCAAGGTCATTCTCGACCTGTTCAATAACTGGGTTTTGCCGATCA
TAGCCGGGTAACGACCCCTC

Downstream 100 bases:

>100_bases
TGGAACTGATCGCCCCATATCTGGGGCAGGCGAGCCCGTGGATGGTCATGTTCATGACCGTGATTGCCCGGCTCTCCTTT
GTCGTCTTCATGATGCCGGG

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 692; Mature: 691

Protein sequence:

>692_residues
MPMQSLLNFTKPTALLAIGLMAIILVMVLPMPAWVLDVGLTLSFALSILIFTTVIFVEKPLDFSSFPSILLASLVLRLAL
NVSSTKLIIGEGHTGTDAAGGVIEGFAMFIMGGNLFVGLVVFGVLVIVNFMVITKGAGRMAEVGARFALDAMPGKQLAID
SDLAVGAITHEEAKLRRQREQEEAGFLGSLDGASKFVKGDAIAGLLITALNLIAGIGFGVVAHQLSVVEALNNYSILTVG
DGLVSQIPAVIVSVAAALLLSKGREEGAIDRALGLQLAGNSTALYIVAGILAIFALLPGLPFLPFIAGAAGFAAVAYFTK
KAADEKAASEETKPEDAAPKAPKIGDSIYADEIHLEVAPDLVNMVLVGENGFESRIDKIRRYIAEEYGFVLPPIRMTDNP
TLKKNEYRMRIQGVRVDSGILRPGQVLALIEENQLPHLAGEKVREPVYKAAARWLPSAKKQELAAAAVPVVEPIEVLATH
MLEVIQSNFSLVFTRMVMMETLDALAAISDVDRASANKRFLDEYIPGKVTPELLLSVLRMLLTERVPIRNLFLIIETVAE
AKPQALPLPRVIELVRQRLAFQIVDRLQDDQGRLPLIQLSTSWEQKFTEYEVTNESGGSDIALPPEIFGELINSVQAKLN
ETAQKGIIAAVATSSRRRRFLQTVLASKGIRNAVVAYEEINSKSKPYIIGVA

Sequences:

>Translated_692_residues
MPMQSLLNFTKPTALLAIGLMAIILVMVLPMPAWVLDVGLTLSFALSILIFTTVIFVEKPLDFSSFPSILLASLVLRLAL
NVSSTKLIIGEGHTGTDAAGGVIEGFAMFIMGGNLFVGLVVFGVLVIVNFMVITKGAGRMAEVGARFALDAMPGKQLAID
SDLAVGAITHEEAKLRRQREQEEAGFLGSLDGASKFVKGDAIAGLLITALNLIAGIGFGVVAHQLSVVEALNNYSILTVG
DGLVSQIPAVIVSVAAALLLSKGREEGAIDRALGLQLAGNSTALYIVAGILAIFALLPGLPFLPFIAGAAGFAAVAYFTK
KAADEKAASEETKPEDAAPKAPKIGDSIYADEIHLEVAPDLVNMVLVGENGFESRIDKIRRYIAEEYGFVLPPIRMTDNP
TLKKNEYRMRIQGVRVDSGILRPGQVLALIEENQLPHLAGEKVREPVYKAAARWLPSAKKQELAAAAVPVVEPIEVLATH
MLEVIQSNFSLVFTRMVMMETLDALAAISDVDRASANKRFLDEYIPGKVTPELLLSVLRMLLTERVPIRNLFLIIETVAE
AKPQALPLPRVIELVRQRLAFQIVDRLQDDQGRLPLIQLSTSWEQKFTEYEVTNESGGSDIALPPEIFGELINSVQAKLN
ETAQKGIIAAVATSSRRRRFLQTVLASKGIRNAVVAYEEINSKSKPYIIGVA
>Mature_691_residues
PMQSLLNFTKPTALLAIGLMAIILVMVLPMPAWVLDVGLTLSFALSILIFTTVIFVEKPLDFSSFPSILLASLVLRLALN
VSSTKLIIGEGHTGTDAAGGVIEGFAMFIMGGNLFVGLVVFGVLVIVNFMVITKGAGRMAEVGARFALDAMPGKQLAIDS
DLAVGAITHEEAKLRRQREQEEAGFLGSLDGASKFVKGDAIAGLLITALNLIAGIGFGVVAHQLSVVEALNNYSILTVGD
GLVSQIPAVIVSVAAALLLSKGREEGAIDRALGLQLAGNSTALYIVAGILAIFALLPGLPFLPFIAGAAGFAAVAYFTKK
AADEKAASEETKPEDAAPKAPKIGDSIYADEIHLEVAPDLVNMVLVGENGFESRIDKIRRYIAEEYGFVLPPIRMTDNPT
LKKNEYRMRIQGVRVDSGILRPGQVLALIEENQLPHLAGEKVREPVYKAAARWLPSAKKQELAAAAVPVVEPIEVLATHM
LEVIQSNFSLVFTRMVMMETLDALAAISDVDRASANKRFLDEYIPGKVTPELLLSVLRMLLTERVPIRNLFLIIETVAEA
KPQALPLPRVIELVRQRLAFQIVDRLQDDQGRLPLIQLSTSWEQKFTEYEVTNESGGSDIALPPEIFGELINSVQAKLNE
TAQKGIIAAVATSSRRRRFLQTVLASKGIRNAVVAYEEINSKSKPYIIGVA

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=549, Percent_Identity=40.9836065573771, Blast_Score=384, Evalue=1e-108,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 74559; Mature: 74428

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMQSLLNFTKPTALLAIGLMAIILVMVLPMPAWVLDVGLTLSFALSILIFTTVIFVEKP
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LDFSSFPSILLASLVLRLALNVSSTKLIIGEGHTGTDAAGGVIEGFAMFIMGGNLFVGLV
CCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHHH
VFGVLVIVNFMVITKGAGRMAEVGARFALDAMPGKQLAIDSDLAVGAITHEEAKLRRQRE
HHHHHHHHHHHHHHCCCCHHHHHHHHHEEECCCCCCEEECCCCCEEEECHHHHHHHHHHH
QEEAGFLGSLDGASKFVKGDAIAGLLITALNLIAGIGFGVVAHQLSVVEALNNYSILTVG
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
DGLVSQIPAVIVSVAAALLLSKGREEGAIDRALGLQLAGNSTALYIVAGILAIFALLPGL
CHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCEECCCCCHHHHHHHHHHHHHHHCCC
PFLPFIAGAAGFAAVAYFTKKAADEKAASEETKPEDAAPKAPKIGDSIYADEIHLEVAPD
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCEEEEECCC
LVNMVLVGENGFESRIDKIRRYIAEEYGFVLPPIRMTDNPTLKKNEYRMRIQGVRVDSGI
CEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCEEEEEEEEEECCCC
LRPGQVLALIEENQLPHLAGEKVREPVYKAAARWLPSAKKQELAAAAVPVVEPIEVLATH
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHH
MLEVIQSNFSLVFTRMVMMETLDALAAISDVDRASANKRFLDEYIPGKVTPELLLSVLRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHH
LLTERVPIRNLFLIIETVAEAKPQALPLPRVIELVRQRLAFQIVDRLQDDQGRLPLIQLS
HHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEC
TSWEQKFTEYEVTNESGGSDIALPPEIFGELINSVQAKLNETAQKGIIAAVATSSRRRRF
CCHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEHEECCCHHHHHH
LQTVLASKGIRNAVVAYEEINSKSKPYIIGVA
HHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure 
PMQSLLNFTKPTALLAIGLMAIILVMVLPMPAWVLDVGLTLSFALSILIFTTVIFVEKP
CHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LDFSSFPSILLASLVLRLALNVSSTKLIIGEGHTGTDAAGGVIEGFAMFIMGGNLFVGLV
CCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHHH
VFGVLVIVNFMVITKGAGRMAEVGARFALDAMPGKQLAIDSDLAVGAITHEEAKLRRQRE
HHHHHHHHHHHHHHCCCCHHHHHHHHHEEECCCCCCEEECCCCCEEEECHHHHHHHHHHH
QEEAGFLGSLDGASKFVKGDAIAGLLITALNLIAGIGFGVVAHQLSVVEALNNYSILTVG
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
DGLVSQIPAVIVSVAAALLLSKGREEGAIDRALGLQLAGNSTALYIVAGILAIFALLPGL
CHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCEECCCCCHHHHHHHHHHHHHHHCCC
PFLPFIAGAAGFAAVAYFTKKAADEKAASEETKPEDAAPKAPKIGDSIYADEIHLEVAPD
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCEEEEECCC
LVNMVLVGENGFESRIDKIRRYIAEEYGFVLPPIRMTDNPTLKKNEYRMRIQGVRVDSGI
CEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCEEEEEEEEEECCCC
LRPGQVLALIEENQLPHLAGEKVREPVYKAAARWLPSAKKQELAAAAVPVVEPIEVLATH
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHH
MLEVIQSNFSLVFTRMVMMETLDALAAISDVDRASANKRFLDEYIPGKVTPELLLSVLRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHH
LLTERVPIRNLFLIIETVAEAKPQALPLPRVIELVRQRLAFQIVDRLQDDQGRLPLIQLS
HHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEC
TSWEQKFTEYEVTNESGGSDIALPPEIFGELINSVQAKLNETAQKGIIAAVATSSRRRRF
CCHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEHEECCCHHHHHH
LQTVLASKGIRNAVVAYEEINSKSKPYIIGVA
HHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1938923; 1732219; 11259647 [H]