Click here to switch to the map view.

The map label for this gene is lhr [C]

Identifier: 114797507

GI number: 114797507

Start: 601239

End: 603866

Strand: Direct

Name: lhr [C]

Synonym: HNE_0604

Alternate gene names: 114797507

Gene position: 601239-603866 (Clockwise)

Preceding gene: 114797574

Following gene: 114800458

Centisome position: 16.23

GC content: 65.83

Gene sequence:

>2628_bases
ATGCCCGATACCGCTCCGCCCCCGTTTCAGCTGCCGCCCGCCTTCGCGGCGTGGTTTGCCAGGCGCGGCTGGTCGCCCCG
TCCGCACCAGCTTGCCCTGGCTGAAACCTCCCTCTCCGGGGGCAGCGCGCTCCTCATCGCCCCGACAGGCGGGGGCAAGA
CGCTCGCCGGCTTCCTCGGCAGCCTGATCGAGCTTGCGCAAAAGCCCCGCTCAAACTCCCATATCCCGAGCCTCCACACC
CTCTACATCTCCCCCCTCAAAGCCCTCGCTGCCGACGTTCAGCGCAATGTCATGACGCCGGTGACCGAGATGGCCCTCCC
CATCCGCATCGAAACCCGCACCGGCGACACCGCCACCCATGTCCGCCAGCGCCAGCGCAAGACCCCGCCGGACATCCTGC
TGACGACGCCCGAACAGCTCGCCCTCCTGATCGCGTCCGACAATGCCGCAAACTTCTTCGCCGATCTCAAATGCGTCATC
ATCGACGAAATCCACGCCATCGCCCCGTCCAAACGCGGCGACCTGCTCTCCCTCGGCCTCGCAACGCTTGCCGAATGGTC
CCCCACCTGCCGCTTCCTCGGCCTCTCCGCCACCGTACGAGACCCGGAGCAACTCGCCGGTTGGCTCGATGTGCGCAGCG
CTCCTTCAACCCCTCTCCCCTCGGGGAGAGGGGCAGGGGTGAGGGGGCAGCCCAGCAGCGCATCGCCCGTGGCCACCTCT
CACGCCCAACCCCTTCTCCCCGAACGGGCGAGGGGGCCAATACCCTCCGTCCACATCATTCAAACCCCGACCACCATAAA
CCCTGACATCGACATCCTCGTCTCCCGCCAGCGCATTCCCTGGTCCGGCCATTCAGGCCGCTTCGCCGTGCCCGAGGTCT
ATGAGGCCATCCGCGACGCGAAGATGACGCTCGTCTTCGTCAACACGCGCAGCCAGGCAGAGCTTCTCTTCCAGGAGCTC
TGGGCCGCCAACGAAGACAACCTCCCCATCGCGCTCCATCATGGCTCGCTCGCCCGCGACCAGCGCGAGCGGGTCGAGGC
CGCAATGGCTGCCGGTCTCCTCAAGGCCGTCGTCTGCACCTCCACCCTCGATCTCGGCATCGACTGGGGCGAGGTTGATC
TCGTCATCCAGATGGGCGCGCCCAAAGGCGCCGCCCGCCTCATCCAGCGCATCGGCCGCTCCAACCACCGTATGGACGAA
GCCAGCAAAGCCCTCCTTGTACCCACAAACCGATTCGAAGTCCTCGAATGCCGCGCCGCCCAGGCCGCCGTCGAAGCCGG
AGAGATCGACGGAGACGGCCCCCGCGCCGGCGCGCTGGACATCCTCGCCCAGCACATCATGGGCCGCGCCTGCGGTGAAG
GCTTCCATCTCCCCGCCCTCTACGATGAAATCCGCCGCGCCCAGCCCTACGCCGCCCTCGACTGGGAAACCTATGAACGC
CTCGTCGATTTCGTCGCCACCGGCGGCTACGCCCTGAAAACCTATGACCGCTTCCACCGGATCGTGCGCCGCGCCGACGG
CCTCTGGGTCGCCCGCACCCCCAGAGACAAACAGGCCCACCGCATGAATGTCGGCGCCATCGTCGAAGCGCCCATGCTGT
CAGTCCGCCTCGCAAGCTTTGCGGGCGGCGCATCTCCCAATAGCGGGGGAGGGGAACAGCGCCGTGCCATAAGAGCAGGC
AGAAAACTCGGCGAAATGGAAGAATACTTCCTCAGCCTCCTCACGCCCGGCGACACCTTCCTCTTCGCCGGCGAAATCCT
CCGCCTGCTCACAATCGACGGTATGGACGCCCTCGTCACCCGCGCCCAGTCAGACAGCCCCGCCATCCCCACCTATAATG
GCGGAAAATTTCCCCTCAGCACGTTCCTCGCAGACCGTGTCCGCCACATGATCCACAATCCCGAAGAATGGAAACACCTG
CCAGACCCCGTGCGCGAATGGTTCGAAATCCAGGAGCTGCGTTCGGCCATTCCGCCGCCCGATCACCTCCTCGTCGAAAC
CTTCCCGCGCGCAGACCGTCATTACCTCGTCTCCTATCCCTTCGAGGGCCGCCTCGCTCACCAGACCCTCGGCATGCTCG
TCACCCGCCGCCTCGAGCGGGCAGGGGCAAAGCCGGTCGGTTTCGTCGCCAGTGAATACGCGATGGCCGTCTGGGGTATG
GAAGACATGCGCGGCCTCGATATGGCAGAGATTTTCCATCCCGAGATGCTGGGCGACGACCTTGAAGAATGGCTCGACGA
AAGCGCCCTGATGAAGCGCACCTTTGCCCACTGCGCCCTCATCTCCGGCCTCATCCACCGGAATATGCCGGGCACGGAGA
AAAACTCCCGTCAGGTCACCTTCTCGACAGACCTCATCTTCGATGTCCTGCGCAGCCACGAGCCCGGCCACATCCTCCTC
CAGGCCACCCGCGCCGACGCCGCCACCGGCCTCCTCGATGTCCGCCGCCTCTCAGACATGCTCGCCCGCATCCACGGCCA
CATCGTCCACAAGCCGCTCGCCAAGATCAGCCCCTTCGCCGTCCCCGTCATGCTCGAGGTTGGCCGCGAACCTGTCTTCG
GCGCATCCGCCATGGAAGCCATCCTCCGCGAAGCCGAAGAAGACCTCGTCCGCGACGCGATGGGCTAG

Upstream 100 bases:

>100_bases
CGGCTCGCTCCTTGAAGTTGCAGCTTGCCGTCAACTTCATCCGTTCCGCAGCAAAATGAAAGAGCCAGACGCTCTGGCTT
GCCCTAGTTTAATCTCTGCC

Downstream 100 bases:

>100_bases
GCGCGCGCCGCTTGCGTGCCTAGCCACCGCGCACCGATGCAGTCGAACACGCGCGCCACAATCTGCTTCCAGAAATCCAG
ACGCCGCTCGGAAACTTCCG

Product: DEAD-box ATP dependent DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 875; Mature: 874

Protein sequence:

>875_residues
MPDTAPPPFQLPPAFAAWFARRGWSPRPHQLALAETSLSGGSALLIAPTGGGKTLAGFLGSLIELAQKPRSNSHIPSLHT
LYISPLKALAADVQRNVMTPVTEMALPIRIETRTGDTATHVRQRQRKTPPDILLTTPEQLALLIASDNAANFFADLKCVI
IDEIHAIAPSKRGDLLSLGLATLAEWSPTCRFLGLSATVRDPEQLAGWLDVRSAPSTPLPSGRGAGVRGQPSSASPVATS
HAQPLLPERARGPIPSVHIIQTPTTINPDIDILVSRQRIPWSGHSGRFAVPEVYEAIRDAKMTLVFVNTRSQAELLFQEL
WAANEDNLPIALHHGSLARDQRERVEAAMAAGLLKAVVCTSTLDLGIDWGEVDLVIQMGAPKGAARLIQRIGRSNHRMDE
ASKALLVPTNRFEVLECRAAQAAVEAGEIDGDGPRAGALDILAQHIMGRACGEGFHLPALYDEIRRAQPYAALDWETYER
LVDFVATGGYALKTYDRFHRIVRRADGLWVARTPRDKQAHRMNVGAIVEAPMLSVRLASFAGGASPNSGGGEQRRAIRAG
RKLGEMEEYFLSLLTPGDTFLFAGEILRLLTIDGMDALVTRAQSDSPAIPTYNGGKFPLSTFLADRVRHMIHNPEEWKHL
PDPVREWFEIQELRSAIPPPDHLLVETFPRADRHYLVSYPFEGRLAHQTLGMLVTRRLERAGAKPVGFVASEYAMAVWGM
EDMRGLDMAEIFHPEMLGDDLEEWLDESALMKRTFAHCALISGLIHRNMPGTEKNSRQVTFSTDLIFDVLRSHEPGHILL
QATRADAATGLLDVRRLSDMLARIHGHIVHKPLAKISPFAVPVMLEVGREPVFGASAMEAILREAEEDLVRDAMG

Sequences:

>Translated_875_residues
MPDTAPPPFQLPPAFAAWFARRGWSPRPHQLALAETSLSGGSALLIAPTGGGKTLAGFLGSLIELAQKPRSNSHIPSLHT
LYISPLKALAADVQRNVMTPVTEMALPIRIETRTGDTATHVRQRQRKTPPDILLTTPEQLALLIASDNAANFFADLKCVI
IDEIHAIAPSKRGDLLSLGLATLAEWSPTCRFLGLSATVRDPEQLAGWLDVRSAPSTPLPSGRGAGVRGQPSSASPVATS
HAQPLLPERARGPIPSVHIIQTPTTINPDIDILVSRQRIPWSGHSGRFAVPEVYEAIRDAKMTLVFVNTRSQAELLFQEL
WAANEDNLPIALHHGSLARDQRERVEAAMAAGLLKAVVCTSTLDLGIDWGEVDLVIQMGAPKGAARLIQRIGRSNHRMDE
ASKALLVPTNRFEVLECRAAQAAVEAGEIDGDGPRAGALDILAQHIMGRACGEGFHLPALYDEIRRAQPYAALDWETYER
LVDFVATGGYALKTYDRFHRIVRRADGLWVARTPRDKQAHRMNVGAIVEAPMLSVRLASFAGGASPNSGGGEQRRAIRAG
RKLGEMEEYFLSLLTPGDTFLFAGEILRLLTIDGMDALVTRAQSDSPAIPTYNGGKFPLSTFLADRVRHMIHNPEEWKHL
PDPVREWFEIQELRSAIPPPDHLLVETFPRADRHYLVSYPFEGRLAHQTLGMLVTRRLERAGAKPVGFVASEYAMAVWGM
EDMRGLDMAEIFHPEMLGDDLEEWLDESALMKRTFAHCALISGLIHRNMPGTEKNSRQVTFSTDLIFDVLRSHEPGHILL
QATRADAATGLLDVRRLSDMLARIHGHIVHKPLAKISPFAVPVMLEVGREPVFGASAMEAILREAEEDLVRDAMG
>Mature_874_residues
PDTAPPPFQLPPAFAAWFARRGWSPRPHQLALAETSLSGGSALLIAPTGGGKTLAGFLGSLIELAQKPRSNSHIPSLHTL
YISPLKALAADVQRNVMTPVTEMALPIRIETRTGDTATHVRQRQRKTPPDILLTTPEQLALLIASDNAANFFADLKCVII
DEIHAIAPSKRGDLLSLGLATLAEWSPTCRFLGLSATVRDPEQLAGWLDVRSAPSTPLPSGRGAGVRGQPSSASPVATSH
AQPLLPERARGPIPSVHIIQTPTTINPDIDILVSRQRIPWSGHSGRFAVPEVYEAIRDAKMTLVFVNTRSQAELLFQELW
AANEDNLPIALHHGSLARDQRERVEAAMAAGLLKAVVCTSTLDLGIDWGEVDLVIQMGAPKGAARLIQRIGRSNHRMDEA
SKALLVPTNRFEVLECRAAQAAVEAGEIDGDGPRAGALDILAQHIMGRACGEGFHLPALYDEIRRAQPYAALDWETYERL
VDFVATGGYALKTYDRFHRIVRRADGLWVARTPRDKQAHRMNVGAIVEAPMLSVRLASFAGGASPNSGGGEQRRAIRAGR
KLGEMEEYFLSLLTPGDTFLFAGEILRLLTIDGMDALVTRAQSDSPAIPTYNGGKFPLSTFLADRVRHMIHNPEEWKHLP
DPVREWFEIQELRSAIPPPDHLLVETFPRADRHYLVSYPFEGRLAHQTLGMLVTRRLERAGAKPVGFVASEYAMAVWGME
DMRGLDMAEIFHPEMLGDDLEEWLDESALMKRTFAHCALISGLIHRNMPGTEKNSRQVTFSTDLIFDVLRSHEPGHILLQ
ATRADAATGLLDVRRLSDMLARIHGHIVHKPLAKISPFAVPVMLEVGREPVFGASAMEAILREAEEDLVRDAMG

Specific function: Unknown

COG id: COG1201

COG function: function code R; Lhr-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787942, Length=958, Percent_Identity=27.4530271398747, Blast_Score=235, Evalue=8e-63,
Organism=Saccharomyces cerevisiae, GI9755332, Length=204, Percent_Identity=28.921568627451, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321710, Length=350, Percent_Identity=25.4285714285714, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24647182, Length=350, Percent_Identity=24, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR013701
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR017170 [H]

Pfam domain/function: PF00270 DEAD; PF08494 DEAD_assoc; PF00271 Helicase_C [H]

EC number: 3.6.1.-

Molecular weight: Translated: 95955; Mature: 95824

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDTAPPPFQLPPAFAAWFARRGWSPRPHQLALAETSLSGGSALLIAPTGGGKTLAGFLG
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHH
SLIELAQKPRSNSHIPSLHTLYISPLKALAADVQRNVMTPVTEMALPIRIETRTGDTATH
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCEEEEEEECCCCCHHHH
VRQRQRKTPPDILLTTPEQLALLIASDNAANFFADLKCVIIDEIHAIAPSKRGDLLSLGL
HHHHHHCCCCCEEEECHHHEEEEEECCCCHHHHHHHHEEEEHHHHHHCCCCCCCCHHHHH
ATLAEWSPTCRFLGLSATVRDPEQLAGWLDVRSAPSTPLPSGRGAGVRGQPSSASPVATS
HHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
HAQPLLPERARGPIPSVHIIQTPTTINPDIDILVSRQRIPWSGHSGRFAVPEVYEAIRDA
CCCCCCCHHHCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHCC
KMTLVFVNTRSQAELLFQELWAANEDNLPIALHHGSLARDQRERVEAAMAAGLLKAVVCT
EEEEEEEECCHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
STLDLGIDWGEVDLVIQMGAPKGAARLIQRIGRSNHRMDEASKALLVPTNRFEVLECRAA
HHHHCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCHHHHCCEEEECCCCHHHHHHHHH
QAAVEAGEIDGDGPRAGALDILAQHIMGRACGEGFHLPALYDEIRRAQPYAALDWETYER
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEECHHHHHH
LVDFVATGGYALKTYDRFHRIVRRADGLWVARTPRDKQAHRMNVGAIVEAPMLSVRLASF
HHHHHHCCCEEEHHHHHHHHHHHHCCCEEEEECCCCCHHHHCCCCHHECCCHHHHHHHHH
AGGASPNSGGGEQRRAIRAGRKLGEMEEYFLSLLTPGDTFLFAGEILRLLTIDGMDALVT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHH
RAQSDSPAIPTYNGGKFPLSTFLADRVRHMIHNPEEWKHLPDPVREWFEIQELRSAIPPP
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCC
DHLLVETFPRADRHYLVSYPFEGRLAHQTLGMLVTRRLERAGAKPVGFVASEYAMAVWGM
CCCHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCH
EDMRGLDMAEIFHPEMLGDDLEEWLDESALMKRTFAHCALISGLIHRNMPGTEKNSRQVT
HHHCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
FSTDLIFDVLRSHEPGHILLQATRADAATGLLDVRRLSDMLARIHGHIVHKPLAKISPFA
EHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VPVMLEVGREPVFGASAMEAILREAEEDLVRDAMG
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PDTAPPPFQLPPAFAAWFARRGWSPRPHQLALAETSLSGGSALLIAPTGGGKTLAGFLG
CCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHH
SLIELAQKPRSNSHIPSLHTLYISPLKALAADVQRNVMTPVTEMALPIRIETRTGDTATH
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCEEEEEEECCCCCHHHH
VRQRQRKTPPDILLTTPEQLALLIASDNAANFFADLKCVIIDEIHAIAPSKRGDLLSLGL
HHHHHHCCCCCEEEECHHHEEEEEECCCCHHHHHHHHEEEEHHHHHHCCCCCCCCHHHHH
ATLAEWSPTCRFLGLSATVRDPEQLAGWLDVRSAPSTPLPSGRGAGVRGQPSSASPVATS
HHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
HAQPLLPERARGPIPSVHIIQTPTTINPDIDILVSRQRIPWSGHSGRFAVPEVYEAIRDA
CCCCCCCHHHCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHCC
KMTLVFVNTRSQAELLFQELWAANEDNLPIALHHGSLARDQRERVEAAMAAGLLKAVVCT
EEEEEEEECCHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
STLDLGIDWGEVDLVIQMGAPKGAARLIQRIGRSNHRMDEASKALLVPTNRFEVLECRAA
HHHHCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCHHHHCCEEEECCCCHHHHHHHHH
QAAVEAGEIDGDGPRAGALDILAQHIMGRACGEGFHLPALYDEIRRAQPYAALDWETYER
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEECHHHHHH
LVDFVATGGYALKTYDRFHRIVRRADGLWVARTPRDKQAHRMNVGAIVEAPMLSVRLASF
HHHHHHCCCEEEHHHHHHHHHHHHCCCEEEEECCCCCHHHHCCCCHHECCCHHHHHHHHH
AGGASPNSGGGEQRRAIRAGRKLGEMEEYFLSLLTPGDTFLFAGEILRLLTIDGMDALVT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHH
RAQSDSPAIPTYNGGKFPLSTFLADRVRHMIHNPEEWKHLPDPVREWFEIQELRSAIPPP
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCC
DHLLVETFPRADRHYLVSYPFEGRLAHQTLGMLVTRRLERAGAKPVGFVASEYAMAVWGM
CCCHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCH
EDMRGLDMAEIFHPEMLGDDLEEWLDESALMKRTFAHCALISGLIHRNMPGTEKNSRQVT
HHHCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
FSTDLIFDVLRSHEPGHILLQATRADAATGLLDVRRLSDMLARIHGHIVHKPLAKISPFA
EHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VPVMLEVGREPVFGASAMEAILREAEEDLVRDAMG
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]