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The map label for this gene is iorB [H]

Identifier: 114797470

GI number: 114797470

Start: 2297397

End: 2299526

Strand: Direct

Name: iorB [H]

Synonym: HNE_2202

Alternate gene names: 114797470

Gene position: 2297397-2299526 (Clockwise)

Preceding gene: 114797647

Following gene: 114797204

Centisome position: 62.01

GC content: 62.21

Gene sequence:

>2130_bases
ATGACGCGCCGCCGGATGATCCTGGGCGGCAGCCTCGTCGGAGGCGCTCTGATCGTCGGCTATGGCGTTACCCACCCGAT
GCAGATTGCCGGGGCCGTCCTGGGAGGGGACCCAAATCCCGAGGACAGTGCGTTCGGCCCGTTCATCCGGATGGCTCCCG
ATGGCTGGGTGACCGTCGTCAACAAACAACAGGAGATGGGTCAGGGTATTCATGCTGGCCTGGCCGCGATGGTGGCCGAA
GAACTCGACGCGGACTGGGACCGTGTCCGCGTGATTGACGCGGACAGCAATTTCCGGGCGTACGGCGCACAGGGGACGGC
AGGCTCCCGATCGGTGGCATCAAACTGGGACGCCATGCGGAATGCCGGCGCCGCCGCCCGCGCCATGTTCGTGAGCGCTG
CAGCCCGGCTCTGGACTACGCCACAGAATTTCATCCAGGTCCGGGACGGGATTGTGTCCGACGCTCAATCCGGGCGCAGC
GCGCCCTTTGCCGAGCTGCTCGCCGCCGCCGCAGCTGAGACGCCGCCCCGGACACCGATACTCAAACAACCCGACGCCTA
CCGGTTGATCGGGACAGACCGTGTCCGGCGTAAGGACTGTGGTCCGAAGACAACCGGCGCGCATATCTATACGCAGGATA
TTCAGCATCCGGATCTTCTTGTCGCGATGGTCGCGCACAGCCCCCGCTTCGGTGGAACACTGGCCCGTTTTGACGCCTCC
GATGCCCTTCAGGTCAAGGGGGTCGTTGACGTCTTTGCAATTGAGACTGGCGTTGCCGTGCTGGCTGAGAATACGGTCTC
AGCCCGCCGGGGGCGGGATGCGCTGAGAATCGAATGGGACGATGAGGAAGCGGAAACCCGCTCCACACCGGATCTTGTGC
GTGAATATCACGAGATTGGATCCGGACGCACCAGCCTGCGCCCCGACATTCTGGAGGCGCGGGGCGACACGGCGGCGGAA
TTCGGGACGGATGCGATCGAGTTTATGATCGATTTCCCCTTTCTCGCCCATGCCCCTATGGAAACGATGGATTGCGTCGC
CCGGGTCGACGGCGGATCCGTGACCATAACGTCCGGCTCACACCTTCCGATCGTCGATCAGGTTCAGGCGGCAAGGGCTG
CGCTGACATTTCCGGCCAATGTCGACATTGAAGTCATACAGTCAGGCGGGTCATTCGGACGGCGGGGACTTATGTCCTCA
GACTATGTTGTTGAATGCGTGCGCATTGCCAAGCGCGCAAAGGCCCGTCCCGTCAAACTCATATGGTCGCGCGAGGACGA
GATGGCATCGGGCTATTATCGCCCGATGGTCCATCACCGGGCCTGGGTTGAGATCGCCCCGGACGGATATCCGGCGAAGT
GGCGCCACCATGTTGTCTCCCAGGCGCTGGTCCCGGTGGGTGAAAATCATCAGTCCTTCGAGGGGATTGCGCACTCACCC
TATTTTTCAACCGCGTCCGTCATCGACGGCAAGGTCTTCTCCCCCCGGTTTCCGGTTCCGGTGTCCTTCTGGCGTTCGGT
CGGTCATTCCCACACCGGCATGGCGATGGAACATATCGTAGATCAGCTCGCGCAACGCGCCGGCCGGGATCCCGCCGACT
ATCGGCGTTATCTGTATCAGCAGGCAAACGCAGAACGGCATCTCGCGGTCCTGGACATGCTGATCCGCCAGGGCGACTGG
GGCCAGCCGATCGACGCCGGATGGGCCAGAGGGATTGCCATCCACGAGGCGTTCGGAACCGTGGTTGGTCAGATCGTGGA
AGTTCAGATCGCCGAAGGCCGGCCACGGGTGCGCCGCGTAGTTGCCGTCGTCGATTGCGGGATAGCCATTTCCCCCAATC
AGATCGCCGCCCAGATGGAAGGCGGGATTGCATTTGGCCTGTCGGCTGCCCTCTATGGCGCGGTCACACTTAAGGACGGG
TATGTTCAGGAGTTAAACTTCGATGCCTATCCGGTGGTTCGGATGAACGATATGCCGGCCGTCGAAACGCATATTATTCC
GTCGACGAACCGTCCAACAGGCATGGGGGAACCCGGCGTTCCGCCGATCGCTCCCGCGGTTGCCAACGCCATTCTTGCAC
TGACAGGAAAACCGACACGGAGCCTGCCATTTCCGGCTCGCGACAGCTAA

Upstream 100 bases:

>100_bases
TCGAAGCCTGGATCGCCACAGGCGCTCTCTGTCCGGAATGATCCGGCCTGCCAACAAAGGACAGCTCGTGACCGATACTC
CCGCTAAGAAACGGTTCCTT

Downstream 100 bases:

>100_bases
GCAGACGCCCGAGACGGCGATGATTGGGCGTCTGACAGGGGCGTTTCAGCGAACGCCGAAATGCTCCGCCAATACAAACC
CGGGAAGAACCCGGCTGACC

Product: putative isoquinoline 1-oxidoreductase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 709; Mature: 708

Protein sequence:

>709_residues
MTRRRMILGGSLVGGALIVGYGVTHPMQIAGAVLGGDPNPEDSAFGPFIRMAPDGWVTVVNKQQEMGQGIHAGLAAMVAE
ELDADWDRVRVIDADSNFRAYGAQGTAGSRSVASNWDAMRNAGAAARAMFVSAAARLWTTPQNFIQVRDGIVSDAQSGRS
APFAELLAAAAAETPPRTPILKQPDAYRLIGTDRVRRKDCGPKTTGAHIYTQDIQHPDLLVAMVAHSPRFGGTLARFDAS
DALQVKGVVDVFAIETGVAVLAENTVSARRGRDALRIEWDDEEAETRSTPDLVREYHEIGSGRTSLRPDILEARGDTAAE
FGTDAIEFMIDFPFLAHAPMETMDCVARVDGGSVTITSGSHLPIVDQVQAARAALTFPANVDIEVIQSGGSFGRRGLMSS
DYVVECVRIAKRAKARPVKLIWSREDEMASGYYRPMVHHRAWVEIAPDGYPAKWRHHVVSQALVPVGENHQSFEGIAHSP
YFSTASVIDGKVFSPRFPVPVSFWRSVGHSHTGMAMEHIVDQLAQRAGRDPADYRRYLYQQANAERHLAVLDMLIRQGDW
GQPIDAGWARGIAIHEAFGTVVGQIVEVQIAEGRPRVRRVVAVVDCGIAISPNQIAAQMEGGIAFGLSAALYGAVTLKDG
YVQELNFDAYPVVRMNDMPAVETHIIPSTNRPTGMGEPGVPPIAPAVANAILALTGKPTRSLPFPARDS

Sequences:

>Translated_709_residues
MTRRRMILGGSLVGGALIVGYGVTHPMQIAGAVLGGDPNPEDSAFGPFIRMAPDGWVTVVNKQQEMGQGIHAGLAAMVAE
ELDADWDRVRVIDADSNFRAYGAQGTAGSRSVASNWDAMRNAGAAARAMFVSAAARLWTTPQNFIQVRDGIVSDAQSGRS
APFAELLAAAAAETPPRTPILKQPDAYRLIGTDRVRRKDCGPKTTGAHIYTQDIQHPDLLVAMVAHSPRFGGTLARFDAS
DALQVKGVVDVFAIETGVAVLAENTVSARRGRDALRIEWDDEEAETRSTPDLVREYHEIGSGRTSLRPDILEARGDTAAE
FGTDAIEFMIDFPFLAHAPMETMDCVARVDGGSVTITSGSHLPIVDQVQAARAALTFPANVDIEVIQSGGSFGRRGLMSS
DYVVECVRIAKRAKARPVKLIWSREDEMASGYYRPMVHHRAWVEIAPDGYPAKWRHHVVSQALVPVGENHQSFEGIAHSP
YFSTASVIDGKVFSPRFPVPVSFWRSVGHSHTGMAMEHIVDQLAQRAGRDPADYRRYLYQQANAERHLAVLDMLIRQGDW
GQPIDAGWARGIAIHEAFGTVVGQIVEVQIAEGRPRVRRVVAVVDCGIAISPNQIAAQMEGGIAFGLSAALYGAVTLKDG
YVQELNFDAYPVVRMNDMPAVETHIIPSTNRPTGMGEPGVPPIAPAVANAILALTGKPTRSLPFPARDS
>Mature_708_residues
TRRRMILGGSLVGGALIVGYGVTHPMQIAGAVLGGDPNPEDSAFGPFIRMAPDGWVTVVNKQQEMGQGIHAGLAAMVAEE
LDADWDRVRVIDADSNFRAYGAQGTAGSRSVASNWDAMRNAGAAARAMFVSAAARLWTTPQNFIQVRDGIVSDAQSGRSA
PFAELLAAAAAETPPRTPILKQPDAYRLIGTDRVRRKDCGPKTTGAHIYTQDIQHPDLLVAMVAHSPRFGGTLARFDASD
ALQVKGVVDVFAIETGVAVLAENTVSARRGRDALRIEWDDEEAETRSTPDLVREYHEIGSGRTSLRPDILEARGDTAAEF
GTDAIEFMIDFPFLAHAPMETMDCVARVDGGSVTITSGSHLPIVDQVQAARAALTFPANVDIEVIQSGGSFGRRGLMSSD
YVVECVRIAKRAKARPVKLIWSREDEMASGYYRPMVHHRAWVEIAPDGYPAKWRHHVVSQALVPVGENHQSFEGIAHSPY
FSTASVIDGKVFSPRFPVPVSFWRSVGHSHTGMAMEHIVDQLAQRAGRDPADYRRYLYQQANAERHLAVLDMLIRQGDWG
QPIDAGWARGIAIHEAFGTVVGQIVEVQIAEGRPRVRRVVAVVDCGIAISPNQIAAQMEGGIAFGLSAALYGAVTLKDGY
VQELNFDAYPVVRMNDMPAVETHIIPSTNRPTGMGEPGVPPIAPAVANAILALTGKPTRSLPFPARDS

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 76582; Mature: 76450

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRRMILGGSLVGGALIVGYGVTHPMQIAGAVLGGDPNPEDSAFGPFIRMAPDGWVTVV
CCCCEEEECCCHHCCEEEEECCCCCHHHHHHHEECCCCCCCCCCCCCEEEECCCCEEEEE
NKQQEMGQGIHAGLAAMVAEELDADWDRVRVIDADSNFRAYGAQGTAGSRSVASNWDAMR
CCHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCCCCCCCHHHHCHHHHH
NAGAAARAMFVSAAARLWTTPQNFIQVRDGIVSDAQSGRSAPFAELLAAAAAETPPRTPI
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCC
LKQPDAYRLIGTDRVRRKDCGPKTTGAHIYTQDIQHPDLLVAMVAHSPRFGGTLARFDAS
CCCCCCEEEECCCHHHHHCCCCCCCCCEEEECCCCCCHHEEHHHHCCCCCCCEEEECCCC
DALQVKGVVDVFAIETGVAVLAENTVSARRGRDALRIEWDDEEAETRSTPDLVREYHEIG
CCEEECCCEEEEEHHCCCEEEECCCHHHHCCCCEEEEEECCCHHHCCCCHHHHHHHHHHC
SGRTSLRPDILEARGDTAAEFGTDAIEFMIDFPFLAHAPMETMDCVARVDGGSVTITSGS
CCCCCCCCHHHHCCCCCHHHHCCHHHHHHCCCCHHHCCCHHHHHHHHCCCCCEEEEECCC
HLPIVDQVQAARAALTFPANVDIEVIQSGGSFGRRGLMSSDYVVECVRIAKRAKARPVKL
CCCHHHHHHHHHHEEECCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEE
IWSREDEMASGYYRPMVHHRAWVEIAPDGYPAKWRHHVVSQALVPVGENHQSFEGIAHSP
EECCCHHHHCCHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHCCCCCCC
YFSTASVIDGKVFSPRFPVPVSFWRSVGHSHTGMAMEHIVDQLAQRAGRDPADYRRYLYQ
CCCCHHHHCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
QANAERHLAVLDMLIRQGDWGQPIDAGWARGIAIHEAFGTVVGQIVEVQIAEGRPRVRRV
HCCCHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHEEEEEECCCCHHHHHH
VAVVDCGIAISPNQIAAQMEGGIAFGLSAALYGAVTLKDGYVQELNFDAYPVVRMNDMPA
HHHEECCCEECCHHHHHHHCCCCHHHHHHHHHEEEEECCCCHHHCCCCCCEEEEECCCCC
VETHIIPSTNRPTGMGEPGVPPIAPAVANAILALTGKPTRSLPFPARDS
CEEEECCCCCCCCCCCCCCCCCCHHHHHHHHEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRRRMILGGSLVGGALIVGYGVTHPMQIAGAVLGGDPNPEDSAFGPFIRMAPDGWVTVV
CCCEEEECCCHHCCEEEEECCCCCHHHHHHHEECCCCCCCCCCCCCEEEECCCCEEEEE
NKQQEMGQGIHAGLAAMVAEELDADWDRVRVIDADSNFRAYGAQGTAGSRSVASNWDAMR
CCHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCCCCCCCHHHHCHHHHH
NAGAAARAMFVSAAARLWTTPQNFIQVRDGIVSDAQSGRSAPFAELLAAAAAETPPRTPI
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCC
LKQPDAYRLIGTDRVRRKDCGPKTTGAHIYTQDIQHPDLLVAMVAHSPRFGGTLARFDAS
CCCCCCEEEECCCHHHHHCCCCCCCCCEEEECCCCCCHHEEHHHHCCCCCCCEEEECCCC
DALQVKGVVDVFAIETGVAVLAENTVSARRGRDALRIEWDDEEAETRSTPDLVREYHEIG
CCEEECCCEEEEEHHCCCEEEECCCHHHHCCCCEEEEEECCCHHHCCCCHHHHHHHHHHC
SGRTSLRPDILEARGDTAAEFGTDAIEFMIDFPFLAHAPMETMDCVARVDGGSVTITSGS
CCCCCCCCHHHHCCCCCHHHHCCHHHHHHCCCCHHHCCCHHHHHHHHCCCCCEEEEECCC
HLPIVDQVQAARAALTFPANVDIEVIQSGGSFGRRGLMSSDYVVECVRIAKRAKARPVKL
CCCHHHHHHHHHHEEECCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEE
IWSREDEMASGYYRPMVHHRAWVEIAPDGYPAKWRHHVVSQALVPVGENHQSFEGIAHSP
EECCCHHHHCCHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHCCCCCCC
YFSTASVIDGKVFSPRFPVPVSFWRSVGHSHTGMAMEHIVDQLAQRAGRDPADYRRYLYQ
CCCCHHHHCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
QANAERHLAVLDMLIRQGDWGQPIDAGWARGIAIHEAFGTVVGQIVEVQIAEGRPRVRRV
HCCCHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHEEEEEECCCCHHHHHH
VAVVDCGIAISPNQIAAQMEGGIAFGLSAALYGAVTLKDGYVQELNFDAYPVVRMNDMPA
HHHEECCCEECCHHHHHHHCCCCHHHHHHHHHEEEEECCCCHHHCCCCCCEEEEECCCCC
VETHIIPSTNRPTGMGEPGVPPIAPAVANAILALTGKPTRSLPFPARDS
CEEEECCCCCCCCCCCCCCCCCCHHHHHHHHEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]