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The map label for this gene is dgoT [H]

Identifier: 114797089

GI number: 114797089

Start: 963728

End: 965227

Strand: Reverse

Name: dgoT [H]

Synonym: HNE_0949

Alternate gene names: 114797089

Gene position: 965227-963728 (Counterclockwise)

Preceding gene: 114799369

Following gene: 114798525

Centisome position: 26.05

GC content: 62.73

Gene sequence:

>1500_bases
ATGACGGCAACCGCAGACGCGGCTGAAACTGGCAACGGGCACATTACCGGTTTCGGCTCCAAGCCGTACCGCTCCTATGT
CCTGCTTGCCCTGACGCTGATTTACACGCTGAACTTTATCGACCGCACCGTCATTACGGTTGTCGCCCAGCCGATCATCA
ACACGTTTTCACTGAGCGATGCGCAATGGGGTCTGCTGACCGGCCCACCCTTTGCGCTGTTCTACGCACTCATGGGCATT
CCGATCGCCATGTGGGCGGACCGGGGCAACCGCGTCTTCATCATCTCTCTGTGCGTCATCATCTGGTCGATCATGACGGT
GTTCTGCGGCCTGGCGGCCAGCTTTATCTGGCTGTTGCTGTTCCGGGTTGGCGTGGCGATTGGCGAGGCAGGCTGCACCC
CGCCCGCCAACTCGATCATCACCGATTATTACCCGCCCAAGAGCCGGGCGAACGCCATCGGCATCTACTCCATGGGTGTT
ACGGTGGGCGGCGTCATGGCGCAGCTGTTCGGCGGCGCGCTGGCAGGCTTGCAGGGCGCCGACTTTGGCAACTTCCTGTC
CTCGATTGGCCTGGGCTGGCTGTTTTCGGGCATCAATTGGGAAGAGGTGGAAGGCTGGCGCCTGGTCTTCGTGATCGTGG
GCGCGCCGGGCATCCTCGTCGCCCTGATACTCTGGCTGACGACGCGCGAACCGCCCCGTGGCTATTCAGATCCGAAGGGA
AAGACACCGCTTGAAAAAGCCGGCTTCTTCGAAGCCTTCCGGGAGTTTGGCGCAAAGCCGACCTTCTGGTCACTCTCTCT
CGGCGCCGCGTTCGTCGCCTTTGTCGGCTATGGGCTGATCAGCTTTCAGGCGCCGTTCCTGATGCGCGTACATGGCGTCA
GCGTTTCGGAAGCGGCGATCCGTTATGGCGCGCCCCTGGCCGCGGTCGCGGCCTTCGGCACTTTTCTGGGCGGTTTCCTG
TCAGAAAAATTCACGCCGCGCTTTCCAGCGATCGTTGCCTGGCTGCCCGGTGTGGGCCTGCTGATTGCCATTCCGGCCTA
TATTGCCGCCTTCCTGACGCCTTCCCTGACGATGGCGTTCTGGATGTGGGTCATCGCCGCCATCGCGCACTACGCCTATC
TCGGCGCGCAATACACCGTGTCGACCGCCATCGTCAGCCCGCGCTCGCGCGCCACGACGGTTTCGGTGCTGCTGCTGATC
GTCAGCCTGATCGGGAACGGCCTCGGCCCGATGTTCACCGGCATGATGAGCAGCGCCTTCATGGGCGGCATCATCAGGAA
GAACGGGCTGGAGGAAGCCTTCGCGACCTTCAATCCGGGCCTCTGCGCCGGTCGGATGGCCGAAATCGGCGAAATGGGAC
CGGCGCTCTGCTCGGCCTATGCCGAGGGCCTGCGCCAGTCGATGGTCGCCACGGTTGTCTTCCTCGTTATTGCCGCCGCG
TTCTATTTCCTCGCCTCCCGCACCTTCCTGAAGGATCGCTGGAGCCCCGCCGCGGATTGA

Upstream 100 bases:

>100_bases
CCTTCCCTGACGATAAGACTTGCAGGCGGCGGCGGGACCGTTACCGTCGAGACATGATACAGCGCCGACAGAAGCGCGTT
TTCCTGGGAGGCGAGCTGAC

Downstream 100 bases:

>100_bases
ATTTCGCAATTCTTGCCTGACTGTCGTGGAGACCCGCATGACCGACGCCGCCACCCCTAGCCAGACAACCACCGAAGCCG
TTCCGGGTTACAAAACCGGA

Product: major facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MTATADAAETGNGHITGFGSKPYRSYVLLALTLIYTLNFIDRTVITVVAQPIINTFSLSDAQWGLLTGPPFALFYALMGI
PIAMWADRGNRVFIISLCVIIWSIMTVFCGLAASFIWLLLFRVGVAIGEAGCTPPANSIITDYYPPKSRANAIGIYSMGV
TVGGVMAQLFGGALAGLQGADFGNFLSSIGLGWLFSGINWEEVEGWRLVFVIVGAPGILVALILWLTTREPPRGYSDPKG
KTPLEKAGFFEAFREFGAKPTFWSLSLGAAFVAFVGYGLISFQAPFLMRVHGVSVSEAAIRYGAPLAAVAAFGTFLGGFL
SEKFTPRFPAIVAWLPGVGLLIAIPAYIAAFLTPSLTMAFWMWVIAAIAHYAYLGAQYTVSTAIVSPRSRATTVSVLLLI
VSLIGNGLGPMFTGMMSSAFMGGIIRKNGLEEAFATFNPGLCAGRMAEIGEMGPALCSAYAEGLRQSMVATVVFLVIAAA
FYFLASRTFLKDRWSPAAD

Sequences:

>Translated_499_residues
MTATADAAETGNGHITGFGSKPYRSYVLLALTLIYTLNFIDRTVITVVAQPIINTFSLSDAQWGLLTGPPFALFYALMGI
PIAMWADRGNRVFIISLCVIIWSIMTVFCGLAASFIWLLLFRVGVAIGEAGCTPPANSIITDYYPPKSRANAIGIYSMGV
TVGGVMAQLFGGALAGLQGADFGNFLSSIGLGWLFSGINWEEVEGWRLVFVIVGAPGILVALILWLTTREPPRGYSDPKG
KTPLEKAGFFEAFREFGAKPTFWSLSLGAAFVAFVGYGLISFQAPFLMRVHGVSVSEAAIRYGAPLAAVAAFGTFLGGFL
SEKFTPRFPAIVAWLPGVGLLIAIPAYIAAFLTPSLTMAFWMWVIAAIAHYAYLGAQYTVSTAIVSPRSRATTVSVLLLI
VSLIGNGLGPMFTGMMSSAFMGGIIRKNGLEEAFATFNPGLCAGRMAEIGEMGPALCSAYAEGLRQSMVATVVFLVIAAA
FYFLASRTFLKDRWSPAAD
>Mature_498_residues
TATADAAETGNGHITGFGSKPYRSYVLLALTLIYTLNFIDRTVITVVAQPIINTFSLSDAQWGLLTGPPFALFYALMGIP
IAMWADRGNRVFIISLCVIIWSIMTVFCGLAASFIWLLLFRVGVAIGEAGCTPPANSIITDYYPPKSRANAIGIYSMGVT
VGGVMAQLFGGALAGLQGADFGNFLSSIGLGWLFSGINWEEVEGWRLVFVIVGAPGILVALILWLTTREPPRGYSDPKGK
TPLEKAGFFEAFREFGAKPTFWSLSLGAAFVAFVGYGLISFQAPFLMRVHGVSVSEAAIRYGAPLAAVAAFGTFLGGFLS
EKFTPRFPAIVAWLPGVGLLIAIPAYIAAFLTPSLTMAFWMWVIAAIAHYAYLGAQYTVSTAIVSPRSRATTVSVLLLIV
SLIGNGLGPMFTGMMSSAFMGGIIRKNGLEEAFATFNPGLCAGRMAEIGEMGPALCSAYAEGLRQSMVATVVFLVIAAAF
YFLASRTFLKDRWSPAAD

Specific function: Intake of galactonate into the cell [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI215490096, Length=455, Percent_Identity=23.956043956044, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI14042968, Length=455, Percent_Identity=23.956043956044, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI194239645, Length=431, Percent_Identity=23.2018561484919, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87082320, Length=216, Percent_Identity=29.6296296296296, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI2367379, Length=310, Percent_Identity=20, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193209775, Length=447, Percent_Identity=23.2662192393736, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17557872, Length=429, Percent_Identity=24.2424242424242, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17539092, Length=506, Percent_Identity=22.5296442687747, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24654041, Length=420, Percent_Identity=24.2857142857143, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24654037, Length=420, Percent_Identity=24.2857142857143, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17864456, Length=423, Percent_Identity=23.1678486997636, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24654039, Length=423, Percent_Identity=23.1678486997636, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24640209, Length=172, Percent_Identity=25.5813953488372, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24654044, Length=254, Percent_Identity=24.4094488188976, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 53252; Mature: 53121

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATADAAETGNGHITGFGSKPYRSYVLLALTLIYTLNFIDRTVITVVAQPIINTFSLSD
CCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AQWGLLTGPPFALFYALMGIPIAMWADRGNRVFIISLCVIIWSIMTVFCGLAASFIWLLL
CCCCCCCCCHHHHHHHHHCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRVGVAIGEAGCTPPANSIITDYYPPKSRANAIGIYSMGVTVGGVMAQLFGGALAGLQGA
HHHHHHHCCCCCCCCCCCCEECCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCC
DFGNFLSSIGLGWLFSGINWEEVEGWRLVFVIVGAPGILVALILWLTTREPPRGYSDPKG
CHHHHHHHHHHHHHHCCCCHHHCCCEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCC
KTPLEKAGFFEAFREFGAKPTFWSLSLGAAFVAFVGYGLISFQAPFLMRVHGVSVSEAAI
CCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHEECCCHHHHHH
RYGAPLAAVAAFGTFLGGFLSEKFTPRFPAIVAWLPGVGLLIAIPAYIAAFLTPSLTMAF
HHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
WMWVIAAIAHYAYLGAQYTVSTAIVSPRSRATTVSVLLLIVSLIGNGLGPMFTGMMSSAF
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
MGGIIRKNGLEEAFATFNPGLCAGRMAEIGEMGPALCSAYAEGLRQSMVATVVFLVIAAA
HHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYFLASRTFLKDRWSPAAD
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TATADAAETGNGHITGFGSKPYRSYVLLALTLIYTLNFIDRTVITVVAQPIINTFSLSD
CCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AQWGLLTGPPFALFYALMGIPIAMWADRGNRVFIISLCVIIWSIMTVFCGLAASFIWLLL
CCCCCCCCCHHHHHHHHHCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRVGVAIGEAGCTPPANSIITDYYPPKSRANAIGIYSMGVTVGGVMAQLFGGALAGLQGA
HHHHHHHCCCCCCCCCCCCEECCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCC
DFGNFLSSIGLGWLFSGINWEEVEGWRLVFVIVGAPGILVALILWLTTREPPRGYSDPKG
CHHHHHHHHHHHHHHCCCCHHHCCCEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCC
KTPLEKAGFFEAFREFGAKPTFWSLSLGAAFVAFVGYGLISFQAPFLMRVHGVSVSEAAI
CCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHEECCCHHHHHH
RYGAPLAAVAAFGTFLGGFLSEKFTPRFPAIVAWLPGVGLLIAIPAYIAAFLTPSLTMAF
HHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
WMWVIAAIAHYAYLGAQYTVSTAIVSPRSRATTVSVLLLIVSLIGNGLGPMFTGMMSSAF
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
MGGIIRKNGLEEAFATFNPGLCAGRMAEIGEMGPALCSAYAEGLRQSMVATVVFLVIAAA
HHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYFLASRTFLKDRWSPAAD
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]