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The map label for this gene is exuT [H]

Identifier: 114798525

GI number: 114798525

Start: 962191

End: 963690

Strand: Reverse

Name: exuT [H]

Synonym: HNE_0948

Alternate gene names: 114798525

Gene position: 963690-962191 (Counterclockwise)

Preceding gene: 114797089

Following gene: 114798237

Centisome position: 26.01

GC content: 61.27

Gene sequence:

>1500_bases
ATGACCGACGCCGCCACCCCTAGCCAGACAACCACCGAAGCCGTTCCGGGTTACAAAACCGGATTCGGAACCCCGCTTTA
CCGCGGCTATGTTTTGTCTTCGCTGCTTGTTGTTTACATCTTCAATTTCATCGACCGCTCGATTTTCGGTATCCTGACCG
AGCCGATGAAACTCTCCCTCCAGCTCGAAGACTGGCATATGGGATTGCTCGGCGGCCTCGCCTTTGCGATTTTCTACACG
ACGCTGGGTATCCCGATTGCGCGCGTTGCCGAACGCCGCAGCCGGATGATGATCATTGTGATCTCGCTGACCCTGTGGAG
CCTGATGACGGTGCTCTGCGGCTTTGCGACGAGCTTCATGACGCTGTTCATTTTCCGCCTGCTCGTAGGCGTAGGCGAGG
CGGGGTGTACGCCGCCGGCACAGTCTGTGATCGCCGATTATTTCAAGCCGACAAGCCGCGCGACGGCCGCTTCAATCTAT
GCGCTCGGCGTTCCGCTGGGCGGGATGCTGGCCGGTCTCGCCGCAGGCCCGATCAATGATTATGTGACCGGCGAGAACGT
CTACAATCTCTTCGGCTCATGGGGCTGGACCTGGGCGCAGGGGCTGGTGGACTGGAATAGCCTGGAAGGCTGGCGCATCG
CGTTTATCGCCGTTGGCCTGCCGGGCGTTCTGTTTGCCCTCATCCTATTCTTCACCGTGAAAGAGCCACCCCGCGGATAT
TCTGATCCTCCGGGCGCGCCGCGCAAAGCGGTACCTGATGGCTTCGGCACAGTGCTGAAGGATCTGATGAAGAAGCCGAC
CTATGTGCATGTTGTGGCCGGCGCGGCGATCGCCTCCTTTGCCGGTTACGGCGTTGCGGCTTTCTCCACCTCCTTTCTGC
TGCGCACCCACGGGCTGACGCTGACCGAAGCGGCGTTGATCTTCTCGCTGGTTCTGGGCGTGATGGCGGCGATTGGCGTG
TTCCTCTCGGGCTTCCTCGCGGACAGGCTGTCCGTGCGGTATCCCACAGCGCTGTCCTGGATGCCGGCGCTGGGCATGGG
GCTTTCCGTGCCGCTTTACTGGCTCGGCTATCTCAGCCCCACCGTGCCGTTGATGATTCCGCCGCTGATGCTGGCGGCCA
CGCTGCACTACTTCTATCTCGGCCCAATGTATGCGGTCTCGGCAGGGGTTGTGGACAGCCGCACACGCGCAACGGCCGTG
GCGATCACTCTGTTTGCGGTGAACCTGATCGGCATCGGCCTTGGCCCCACGCTGATCGGCTTCCTCTCCACCGGCCTCAA
GACGATGATGTTGGATGGCAATACGATCGGCCTCACCCTGCAGATGTGTAAGGACGTCACCGTGCTCGCCGCTGACCAGG
CCGCTGCCTGTCGCGACGCCGATGCCCGCGGCCTGCAATGGTCGATCATCATCTTTGCTTCGCTCTATGGCTGGGCGGCG
ATCCACTACCTGCTCGCCGGCAAGACACTTAGCCGTGACATGCTCTCCAAAACTGCGTAA

Upstream 100 bases:

>100_bases
GCGTTCTATTTCCTCGCCTCCCGCACCTTCCTGAAGGATCGCTGGAGCCCCGCCGCGGATTGAATTTCGCAATTCTTGCC
TGACTGTCGTGGAGACCCGC

Downstream 100 bases:

>100_bases
GGGCGCCGCCTATGGCGGTATATACGCAAGTTTCTGATGAAGCCCTCGCAGGGTTCCTCGCCGGGTATGATCTCGGCGAG
GCGCTTGCGTTCAAGGGCAT

Product: major facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MTDAATPSQTTTEAVPGYKTGFGTPLYRGYVLSSLLVVYIFNFIDRSIFGILTEPMKLSLQLEDWHMGLLGGLAFAIFYT
TLGIPIARVAERRSRMMIIVISLTLWSLMTVLCGFATSFMTLFIFRLLVGVGEAGCTPPAQSVIADYFKPTSRATAASIY
ALGVPLGGMLAGLAAGPINDYVTGENVYNLFGSWGWTWAQGLVDWNSLEGWRIAFIAVGLPGVLFALILFFTVKEPPRGY
SDPPGAPRKAVPDGFGTVLKDLMKKPTYVHVVAGAAIASFAGYGVAAFSTSFLLRTHGLTLTEAALIFSLVLGVMAAIGV
FLSGFLADRLSVRYPTALSWMPALGMGLSVPLYWLGYLSPTVPLMIPPLMLAATLHYFYLGPMYAVSAGVVDSRTRATAV
AITLFAVNLIGIGLGPTLIGFLSTGLKTMMLDGNTIGLTLQMCKDVTVLAADQAAACRDADARGLQWSIIIFASLYGWAA
IHYLLAGKTLSRDMLSKTA

Sequences:

>Translated_499_residues
MTDAATPSQTTTEAVPGYKTGFGTPLYRGYVLSSLLVVYIFNFIDRSIFGILTEPMKLSLQLEDWHMGLLGGLAFAIFYT
TLGIPIARVAERRSRMMIIVISLTLWSLMTVLCGFATSFMTLFIFRLLVGVGEAGCTPPAQSVIADYFKPTSRATAASIY
ALGVPLGGMLAGLAAGPINDYVTGENVYNLFGSWGWTWAQGLVDWNSLEGWRIAFIAVGLPGVLFALILFFTVKEPPRGY
SDPPGAPRKAVPDGFGTVLKDLMKKPTYVHVVAGAAIASFAGYGVAAFSTSFLLRTHGLTLTEAALIFSLVLGVMAAIGV
FLSGFLADRLSVRYPTALSWMPALGMGLSVPLYWLGYLSPTVPLMIPPLMLAATLHYFYLGPMYAVSAGVVDSRTRATAV
AITLFAVNLIGIGLGPTLIGFLSTGLKTMMLDGNTIGLTLQMCKDVTVLAADQAAACRDADARGLQWSIIIFASLYGWAA
IHYLLAGKTLSRDMLSKTA
>Mature_498_residues
TDAATPSQTTTEAVPGYKTGFGTPLYRGYVLSSLLVVYIFNFIDRSIFGILTEPMKLSLQLEDWHMGLLGGLAFAIFYTT
LGIPIARVAERRSRMMIIVISLTLWSLMTVLCGFATSFMTLFIFRLLVGVGEAGCTPPAQSVIADYFKPTSRATAASIYA
LGVPLGGMLAGLAAGPINDYVTGENVYNLFGSWGWTWAQGLVDWNSLEGWRIAFIAVGLPGVLFALILFFTVKEPPRGYS
DPPGAPRKAVPDGFGTVLKDLMKKPTYVHVVAGAAIASFAGYGVAAFSTSFLLRTHGLTLTEAALIFSLVLGVMAAIGVF
LSGFLADRLSVRYPTALSWMPALGMGLSVPLYWLGYLSPTVPLMIPPLMLAATLHYFYLGPMYAVSAGVVDSRTRATAVA
ITLFAVNLIGIGLGPTLIGFLSTGLKTMMLDGNTIGLTLQMCKDVTVLAADQAAACRDADARGLQWSIIIFASLYGWAAI
HYLLAGKTLSRDMLSKTA

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI215490096, Length=484, Percent_Identity=25, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI14042968, Length=484, Percent_Identity=25, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI215490100, Length=442, Percent_Identity=26.0180995475113, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI185136021, Length=444, Percent_Identity=23.6486486486486, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI87082320, Length=423, Percent_Identity=25.0591016548463, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17539092, Length=429, Percent_Identity=25.4079254079254, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI193209775, Length=432, Percent_Identity=25.6944444444444, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71992409, Length=429, Percent_Identity=24.9417249417249, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17557872, Length=309, Percent_Identity=22.6537216828479, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24654041, Length=433, Percent_Identity=23.5565819861432, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24654037, Length=433, Percent_Identity=23.5565819861432, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI17864456, Length=429, Percent_Identity=24.2424242424242, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24654039, Length=429, Percent_Identity=24.2424242424242, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24640209, Length=370, Percent_Identity=22.1621621621622, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24654044, Length=265, Percent_Identity=24.1509433962264, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 53385; Mature: 53253

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAATPSQTTTEAVPGYKTGFGTPLYRGYVLSSLLVVYIFNFIDRSIFGILTEPMKLSL
CCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
QLEDWHMGLLGGLAFAIFYTTLGIPIARVAERRSRMMIIVISLTLWSLMTVLCGFATSFM
EECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHH
TLFIFRLLVGVGEAGCTPPAQSVIADYFKPTSRATAASIYALGVPLGGMLAGLAAGPIND
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCC
YVTGENVYNLFGSWGWTWAQGLVDWNSLEGWRIAFIAVGLPGVLFALILFFTVKEPPRGY
CCCCCHHHHHHHCCCHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCC
SDPPGAPRKAVPDGFGTVLKDLMKKPTYVHVVAGAAIASFAGYGVAAFSTSFLLRTHGLT
CCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHHHHCCCH
LTEAALIFSLVLGVMAAIGVFLSGFLADRLSVRYPTALSWMPALGMGLSVPLYWLGYLSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHCC
TVPLMIPPLMLAATLHYFYLGPMYAVSAGVVDSRTRATAVAITLFAVNLIGIGLGPTLIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
FLSTGLKTMMLDGNTIGLTLQMCKDVTVLAADQAAACRDADARGLQWSIIIFASLYGWAA
HHHHCCCEEEECCCEEEEEHHHHCCCEEEECCCHHHHCCCCCCCCEEHHHHHHHHHHHHH
IHYLLAGKTLSRDMLSKTA
HHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure 
TDAATPSQTTTEAVPGYKTGFGTPLYRGYVLSSLLVVYIFNFIDRSIFGILTEPMKLSL
CCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
QLEDWHMGLLGGLAFAIFYTTLGIPIARVAERRSRMMIIVISLTLWSLMTVLCGFATSFM
EECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHH
TLFIFRLLVGVGEAGCTPPAQSVIADYFKPTSRATAASIYALGVPLGGMLAGLAAGPIND
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCC
YVTGENVYNLFGSWGWTWAQGLVDWNSLEGWRIAFIAVGLPGVLFALILFFTVKEPPRGY
CCCCCHHHHHHHCCCHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCC
SDPPGAPRKAVPDGFGTVLKDLMKKPTYVHVVAGAAIASFAGYGVAAFSTSFLLRTHGLT
CCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHHHHCCCH
LTEAALIFSLVLGVMAAIGVFLSGFLADRLSVRYPTALSWMPALGMGLSVPLYWLGYLSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHCC
TVPLMIPPLMLAATLHYFYLGPMYAVSAGVVDSRTRATAVAITLFAVNLIGIGLGPTLIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
FLSTGLKTMMLDGNTIGLTLQMCKDVTVLAADQAAACRDADARGLQWSIIIFASLYGWAA
HHHHCCCEEEECCCEEEEEHHHHCCCEEEECCCHHHHCCCCCCCCEEHHHHHHHHHHHHH
IHYLLAGKTLSRDMLSKTA
HHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]