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The map label for this gene is selD

Identifier: 114331639

GI number: 114331639

Start: 1738073

End: 1739122

Strand: Direct

Name: selD

Synonym: Neut_1654

Alternate gene names: 114331639

Gene position: 1738073-1739122 (Clockwise)

Preceding gene: 114331635

Following gene: 114331640

Centisome position: 65.32

GC content: 50.67

Gene sequence:

>1050_bases
ATGCATCCAGAAAAAATCGCACTGACACAAACGGTACAAAAAGGCGGGTGTGCCGCCAAGGTTGCCGCCACAACATTACA
CCGGATTTTGCAGCAAGTCAGATTTCCAGCTGCACACTCTGCGTTGATGGTGGATGGCCGCTATTTTGACGATGCCGCCA
TCTACAAAATCAATGAACAAACTGCTCTGGTGCAAACACTGGATTTCTTCACGCCGATTGTTGATACTCCAAGACTGTTT
GGTGAAATTGCTGCCGCCAATGCTATCAGCGATGTGTATGCCATGGGTGGCAGGCCCGTTACCGCCATGGGTATTCTGGC
ATTTCCGCTGGCCACCTTATCCGAACACATCATCGTTGATGTCCTGCAAGGTGCCAGCGATAAGATCGCTGAAGCAGGTG
CCAATTTTGTCGGCGGCCATTCAATTGATGATGACACCTTGAAGTTTGGCCTATCGGTCACCGGGTTAGTCAATCCGCAG
CAGGTATGGACCAATGCCAACGCACAATCGGGAGATCATTTGGTTTTGACCAAGGCGCTGGGAACAGGCACCCTGACAGC
CGGAATAAAACGGCAACAATTGCAGGAGAAGGACATCATGGACGCGCTAGAAAGCATGGCGGCCATCAATAACGTCATCG
ACTATCTATCACCGGATTTGCTGGCAGCTATCCATGCCGCTACCGACATCACCGGCTTCGGCTTTTCCGGCCACGCCATG
CAACTAGCAAACGCCAGCAACGTTACCCTGAGCATTGCAACTGGTAATCTTCCCAGGTTTGACAAAGCTTTCTACTGTCT
GAAAAATAGTTTTCTGACCAAAGCACACCGGACCAATGCAGAGTACACCACGCCACATATCGACGATGCAAAACTGGATG
CGCTGTACAAACTGCTAATTCACGATCCGCAAACCAGTGGTGGTTTATTATTAAGCGTGGTGCCCGAAGCCAGCCAGCTC
GTGCTGCAGGCACTGCGCACATACTTCAAGCCAGCAGCAATAGTGGGAACCGTTCATCCTCGTCAAGATAAAGCGGTGCA
ATTTGAATAA

Upstream 100 bases:

>100_bases
AGATCGCTGTGCTGACAACCTGAAAACCCGTTTAATTCGGCACTAACCAGTATTTCACTGGATACTCGTTACAGCAGAAC
ACTTTTTATTTTGAATATTT

Downstream 100 bases:

>100_bases
TCCAAACATTGATAGCGATGAGCTAACAGCTTTATTCACAGCGGATACGCCACTGATTGACGTACGTGCACCGCTTGAAT
TCATACTGGGATCCCTGCCC

Product: selenide, water dikinase

Products: NA

Alternate protein names: Selenium donor protein; Selenophosphate synthase

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MHPEKIALTQTVQKGGCAAKVAATTLHRILQQVRFPAAHSALMVDGRYFDDAAIYKINEQTALVQTLDFFTPIVDTPRLF
GEIAAANAISDVYAMGGRPVTAMGILAFPLATLSEHIIVDVLQGASDKIAEAGANFVGGHSIDDDTLKFGLSVTGLVNPQ
QVWTNANAQSGDHLVLTKALGTGTLTAGIKRQQLQEKDIMDALESMAAINNVIDYLSPDLLAAIHAATDITGFGFSGHAM
QLANASNVTLSIATGNLPRFDKAFYCLKNSFLTKAHRTNAEYTTPHIDDAKLDALYKLLIHDPQTSGGLLLSVVPEASQL
VLQALRTYFKPAAIVGTVHPRQDKAVQFE

Sequences:

>Translated_349_residues
MHPEKIALTQTVQKGGCAAKVAATTLHRILQQVRFPAAHSALMVDGRYFDDAAIYKINEQTALVQTLDFFTPIVDTPRLF
GEIAAANAISDVYAMGGRPVTAMGILAFPLATLSEHIIVDVLQGASDKIAEAGANFVGGHSIDDDTLKFGLSVTGLVNPQ
QVWTNANAQSGDHLVLTKALGTGTLTAGIKRQQLQEKDIMDALESMAAINNVIDYLSPDLLAAIHAATDITGFGFSGHAM
QLANASNVTLSIATGNLPRFDKAFYCLKNSFLTKAHRTNAEYTTPHIDDAKLDALYKLLIHDPQTSGGLLLSVVPEASQL
VLQALRTYFKPAAIVGTVHPRQDKAVQFE
>Mature_349_residues
MHPEKIALTQTVQKGGCAAKVAATTLHRILQQVRFPAAHSALMVDGRYFDDAAIYKINEQTALVQTLDFFTPIVDTPRLF
GEIAAANAISDVYAMGGRPVTAMGILAFPLATLSEHIIVDVLQGASDKIAEAGANFVGGHSIDDDTLKFGLSVTGLVNPQ
QVWTNANAQSGDHLVLTKALGTGTLTAGIKRQQLQEKDIMDALESMAAINNVIDYLSPDLLAAIHAATDITGFGFSGHAM
QLANASNVTLSIATGNLPRFDKAFYCLKNSFLTKAHRTNAEYTTPHIDDAKLDALYKLLIHDPQTSGGLLLSVVPEASQL
VLQALRTYFKPAAIVGTVHPRQDKAVQFE

Specific function: Synthesizes selenophosphate from selenide and ATP

COG id: COG0709

COG function: function code E; Selenophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selenophosphate synthase 1 family. Class I subfamily

Homologues:

Organism=Homo sapiens, GI24797148, Length=220, Percent_Identity=34.5454545454545, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI15011844, Length=221, Percent_Identity=32.579185520362, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1788062, Length=322, Percent_Identity=37.5776397515528, Blast_Score=194, Evalue=9e-51,
Organism=Caenorhabditis elegans, GI17543426, Length=357, Percent_Identity=28.2913165266106, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24653602, Length=275, Percent_Identity=33.4545454545455, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24653604, Length=275, Percent_Identity=33.4545454545455, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI28574119, Length=290, Percent_Identity=28.6206896551724, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28574118, Length=275, Percent_Identity=29.4545454545455, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SELD_NITEC (Q0AFI6)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_747861.1
- ProteinModelPortal:   Q0AFI6
- STRING:   Q0AFI6
- GeneID:   4273807
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_1654
- NMPDR:   fig|335283.3.peg.2205
- eggNOG:   COG0709
- HOGENOM:   HBG383791
- OMA:   HKLARAS
- PhylomeDB:   Q0AFI6
- ProtClustDB:   CLSK585444
- BioCyc:   NEUT335283:NEUT_1654-MONOMER
- HAMAP:   MF_00625
- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR004536
- InterPro:   IPR023061
- PIRSF:   PIRSF036407
- TIGRFAMs:   TIGR00476

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C; SSF56042 AIR_synth_C; SSF55326 PurM_N-like

EC number: =2.7.9.3

Molecular weight: Translated: 37391; Mature: 37391

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: ACT_SITE 17-17

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPEKIALTQTVQKGGCAAKVAATTLHRILQQVRFPAAHSALMVDGRYFDDAAIYKINEQ
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCEEECCEEEEEECCH
TALVQTLDFFTPIVDTPRLFGEIAAANAISDVYAMGGRPVTAMGILAFPLATLSEHIIVD
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VLQGASDKIAEAGANFVGGHSIDDDTLKFGLSVTGLVNPQQVWTNANAQSGDHLVLTKAL
HHHCCCHHHHHCCCCCCCCCCCCHHHHEECCEEEECCCHHHHHCCCCCCCCCEEEEEEEC
GTGTLTAGIKRQQLQEKDIMDALESMAAINNVIDYLSPDLLAAIHAATDITGFGFSGHAM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCEE
QLANASNVTLSIATGNLPRFDKAFYCLKNSFLTKAHRTNAEYTTPHIDDAKLDALYKLLI
EECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
HDPQTSGGLLLSVVPEASQLVLQALRTYFKPAAIVGTVHPRQDKAVQFE
CCCCCCCCEEEEECCHHHHHHHHHHHHHCCCHHEEECCCCCCCCCCCCC
>Mature Secondary Structure
MHPEKIALTQTVQKGGCAAKVAATTLHRILQQVRFPAAHSALMVDGRYFDDAAIYKINEQ
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCEEECCEEEEEECCH
TALVQTLDFFTPIVDTPRLFGEIAAANAISDVYAMGGRPVTAMGILAFPLATLSEHIIVD
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VLQGASDKIAEAGANFVGGHSIDDDTLKFGLSVTGLVNPQQVWTNANAQSGDHLVLTKAL
HHHCCCHHHHHCCCCCCCCCCCCHHHHEECCEEEECCCHHHHHCCCCCCCCCEEEEEEEC
GTGTLTAGIKRQQLQEKDIMDALESMAAINNVIDYLSPDLLAAIHAATDITGFGFSGHAM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCEE
QLANASNVTLSIATGNLPRFDKAFYCLKNSFLTKAHRTNAEYTTPHIDDAKLDALYKLLI
EECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
HDPQTSGGLLLSVVPEASQLVLQALRTYFKPAAIVGTVHPRQDKAVQFE
CCCCCCCCEEEEECCHHHHHHHHHHHHHCCCHHEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA