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The map label for this gene is mreB [H]

Identifier: 114331579

GI number: 114331579

Start: 1673277

End: 1674338

Strand: Reverse

Name: mreB [H]

Synonym: Neut_1592

Alternate gene names: 114331579

Gene position: 1674338-1673277 (Counterclockwise)

Preceding gene: 114331583

Following gene: 114331578

Centisome position: 62.92

GC content: 49.81

Gene sequence:

>1062_bases
ATGTTTAATTTCCTGAGCAATAACTTTCTGGGCGGCTATTTTTCGACGGATATGGCTGTTGATTTAGGCACTGCCAATAC
ATTGATCTATGTGCGTGGCCAGGGCATTGTGCTGAATGAGCCTTCGGTGGTTGCCATACGCCACGAAGGGGGGCCGGGCG
GCAAGCGCATGATTCAGCAGGTTGGACAGGCTGCAAAACAAATGCTGGGCCGTACCCCGGGCAACATTACGGCAATCCGG
CCAATGAAGGACGGTGTTATTGCAGACTTCACAGTCACCGAGCAGATGCTTAAACAATTCATCCGAAAAGCCCATCCTCC
CCGTTTATTTTCAGCAAATCCCCGTATTGTTATTTCTGTGCCTTGTGGTTCCACCCAGGTGGAACGGCGTGCAATCCGGG
AGGCGGCTTACGGCGCAGGGGCGCGTAAGGTCGAGCTGATTGAAGAACCTATGGCGGCAGCGCTGGGCGCGGATTTGCCG
GTTGAAACTCCAATTGGCTGCATGGTAGTTGATATTGGCGGAGGGACGACAGAAGTCGCAGTGATTTCGCTGGGAGGAGT
TGTTTATTCCAATTCGGTACGAGTTGGTGGTGACAGGTTTGATGAGGCAATTATCAATTACATCCGTCGTAATTACGGAA
TTATGATTGGTGAAGTAACGGCTGAGATTATCAAATCAGAAATTGGATCGGCTTATCCGGGCTCGGAAGTCCGGGAAATA
GAAGTCAAAGGACGAAATCTGGCTGAAGGTATTCCTCGCAGCTTTACAATCTCCAGTAATGAGATTCTGGAAGCTTTGGC
AGAGCCGCTTAATAGTATTGTTAGTGCAGTTAAAACCGCATTGGAGCAAACGCCTCCTGAACTCGGTTCCGATATTGCAG
AAATGGGAATGGTGATGACAGGGGGGGGGGCGCTGTTGCGAGATATAGACCGTCTGATTATGGAAGAGACAGGGTTGTCG
GTTATTATTGCGGATGATCCGCTTACCTGTGTTGTGCGGGGTGCGGGAATGGCCCTGGATAGCATTGATCATTCGGTTGG
AATTTTTGTTAGAGATTATTAA

Upstream 100 bases:

>100_bases
ATGTTTTTATACATTTGCGGCGTTTGCTCCAAGAGCGAAATAATGAAATACCTGCAGTGCGTGTAACATACCGGATCTGT
CATACTGGAATATCGTCATT

Downstream 100 bases:

>100_bases
TTTATTTGTCTTTCCCGCCTTCTTCCATGGTGCAAGTTGTCATATAACGTAAGGGCGCGTCGGATTTCTGGGGTCTGTTT
ATGTGCTGCCAATTAGCCTG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MFNFLSNNFLGGYFSTDMAVDLGTANTLIYVRGQGIVLNEPSVVAIRHEGGPGGKRMIQQVGQAAKQMLGRTPGNITAIR
PMKDGVIADFTVTEQMLKQFIRKAHPPRLFSANPRIVISVPCGSTQVERRAIREAAYGAGARKVELIEEPMAAALGADLP
VETPIGCMVVDIGGGTTEVAVISLGGVVYSNSVRVGGDRFDEAIINYIRRNYGIMIGEVTAEIIKSEIGSAYPGSEVREI
EVKGRNLAEGIPRSFTISSNEILEALAEPLNSIVSAVKTALEQTPPELGSDIAEMGMVMTGGGALLRDIDRLIMEETGLS
VIIADDPLTCVVRGAGMALDSIDHSVGIFVRDY

Sequences:

>Translated_353_residues
MFNFLSNNFLGGYFSTDMAVDLGTANTLIYVRGQGIVLNEPSVVAIRHEGGPGGKRMIQQVGQAAKQMLGRTPGNITAIR
PMKDGVIADFTVTEQMLKQFIRKAHPPRLFSANPRIVISVPCGSTQVERRAIREAAYGAGARKVELIEEPMAAALGADLP
VETPIGCMVVDIGGGTTEVAVISLGGVVYSNSVRVGGDRFDEAIINYIRRNYGIMIGEVTAEIIKSEIGSAYPGSEVREI
EVKGRNLAEGIPRSFTISSNEILEALAEPLNSIVSAVKTALEQTPPELGSDIAEMGMVMTGGGALLRDIDRLIMEETGLS
VIIADDPLTCVVRGAGMALDSIDHSVGIFVRDY
>Mature_353_residues
MFNFLSNNFLGGYFSTDMAVDLGTANTLIYVRGQGIVLNEPSVVAIRHEGGPGGKRMIQQVGQAAKQMLGRTPGNITAIR
PMKDGVIADFTVTEQMLKQFIRKAHPPRLFSANPRIVISVPCGSTQVERRAIREAAYGAGARKVELIEEPMAAALGADLP
VETPIGCMVVDIGGGTTEVAVISLGGVVYSNSVRVGGDRFDEAIINYIRRNYGIMIGEVTAEIIKSEIGSAYPGSEVREI
EVKGRNLAEGIPRSFTISSNEILEALAEPLNSIVSAVKTALEQTPPELGSDIAEMGMVMTGGGALLRDIDRLIMEETGLS
VIIADDPLTCVVRGAGMALDSIDHSVGIFVRDY

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=339, Percent_Identity=71.6814159292035, Blast_Score=483, Evalue=1e-138,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 37639; Mature: 37639

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNFLSNNFLGGYFSTDMAVDLGTANTLIYVRGQGIVLNEPSVVAIRHEGGPGGKRMIQQ
CCCCCCCCCCCCEECCCEEEEECCCCEEEEEECCEEEECCCCEEEEEECCCCCHHHHHHH
VGQAAKQMLGRTPGNITAIRPMKDGVIADFTVTEQMLKQFIRKAHPPRLFSANPRIVISV
HHHHHHHHHCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHCCCCCEECCCCEEEEEE
PCGSTQVERRAIREAAYGAGARKVELIEEPMAAALGADLPVETPIGCMVVDIGGGTTEVA
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEE
VISLGGVVYSNSVRVGGDRFDEAIINYIRRNYGIMIGEVTAEIIKSEIGSAYPGSEVREI
EEEECCEEEECCEEECCHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHCCCCCCCCEEEE
EVKGRNLAEGIPRSFTISSNEILEALAEPLNSIVSAVKTALEQTPPELGSDIAEMGMVMT
EECCCHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHCCEEEE
GGGALLRDIDRLIMEETGLSVIIADDPLTCVVRGAGMALDSIDHSVGIFVRDY
CCCHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCHHCCCCCEEEEEECC
>Mature Secondary Structure
MFNFLSNNFLGGYFSTDMAVDLGTANTLIYVRGQGIVLNEPSVVAIRHEGGPGGKRMIQQ
CCCCCCCCCCCCEECCCEEEEECCCCEEEEEECCEEEECCCCEEEEEECCCCCHHHHHHH
VGQAAKQMLGRTPGNITAIRPMKDGVIADFTVTEQMLKQFIRKAHPPRLFSANPRIVISV
HHHHHHHHHCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHCCCCCEECCCCEEEEEE
PCGSTQVERRAIREAAYGAGARKVELIEEPMAAALGADLPVETPIGCMVVDIGGGTTEVA
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEE
VISLGGVVYSNSVRVGGDRFDEAIINYIRRNYGIMIGEVTAEIIKSEIGSAYPGSEVREI
EEEECCEEEECCEEECCHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHCCCCCCCCEEEE
EVKGRNLAEGIPRSFTISSNEILEALAEPLNSIVSAVKTALEQTPPELGSDIAEMGMVMT
EECCCHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHCCEEEE
GGGALLRDIDRLIMEETGLSVIIADDPLTCVVRGAGMALDSIDHSVGIFVRDY
CCCHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]