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The map label for this gene is mreD [H]

Identifier: 114331577

GI number: 114331577

Start: 1671501

End: 1672052

Strand: Reverse

Name: mreD [H]

Synonym: Neut_1590

Alternate gene names: 114331577

Gene position: 1672052-1671501 (Counterclockwise)

Preceding gene: 114331578

Following gene: 114331576

Centisome position: 62.83

GC content: 42.21

Gene sequence:

>552_bases
ATGCATCCCAGACAAAACGGAAAATCTAGAATCAGGCGTTATGATTACGAAATCCAGGAATTTTTATTTCCTGCAAGAAA
ATCACTGATTTATATCAGTTTGATAACGGCAGTTTTAATTAACCTGATGCCGTTTGATAAAGTGATACTGGTTTTGCGCC
CGGATTTTGTTGCGCTGACATTACTCTACTGGAATATCTATCAACCACAGCAAGCGGGCATGAGTATCGCTTTCATAAGT
GGTCTGTTCATGGATGTCATCGATGTCAGTATCATGGGACAGCATGCCATTGCATATTGCCTGATCACGTTTTTTGCCTT
GATCCTGTATAGACGTTTGCGCTTGTTCAATGCCTTTCAGCAAATTCCCGCAGTTTTATGGATACTGTTATCAGGGCAAG
GAGTGGTATTTTTGACCGGGATTCTGGCAGGATCGTATATTCCTGAGTGGTATATTTTCCTGGCGAGTGTAACCGGGGCG
TTATGTTGGCCCTTATTGGTTTTTCTGCTGGGAATATTTCGTAAGCAGCGAATTGATCGCGATGAAGTATGA

Upstream 100 bases:

>100_bases
ATATGTACTCCCGTGGCGGGCGTAGATCGGCACAGGCAAGTTCTCATCCTGACCAGTTCGCCACCACCTGTTACGGAAAT
ACCAGATAACCCTGAATCCC

Downstream 100 bases:

>100_bases
GTGATATTGTAGAGTTACGTAATCATATACGTGAAACTCGGCATTTTCGCATCAGGTTGGTGATCAGTGCGATTGGTGTC
GTGGTTTTGTTCAGTTTGCT

Product: rod shape-determining protein MreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MHPRQNGKSRIRRYDYEIQEFLFPARKSLIYISLITAVLINLMPFDKVILVLRPDFVALTLLYWNIYQPQQAGMSIAFIS
GLFMDVIDVSIMGQHAIAYCLITFFALILYRRLRLFNAFQQIPAVLWILLSGQGVVFLTGILAGSYIPEWYIFLASVTGA
LCWPLLVFLLGIFRKQRIDRDEV

Sequences:

>Translated_183_residues
MHPRQNGKSRIRRYDYEIQEFLFPARKSLIYISLITAVLINLMPFDKVILVLRPDFVALTLLYWNIYQPQQAGMSIAFIS
GLFMDVIDVSIMGQHAIAYCLITFFALILYRRLRLFNAFQQIPAVLWILLSGQGVVFLTGILAGSYIPEWYIFLASVTGA
LCWPLLVFLLGIFRKQRIDRDEV
>Mature_183_residues
MHPRQNGKSRIRRYDYEIQEFLFPARKSLIYISLITAVLINLMPFDKVILVLRPDFVALTLLYWNIYQPQQAGMSIAFIS
GLFMDVIDVSIMGQHAIAYCLITFFALILYRRLRLFNAFQQIPAVLWILLSGQGVVFLTGILAGSYIPEWYIFLASVTGA
LCWPLLVFLLGIFRKQRIDRDEV

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG2891

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreD family [H]

Homologues:

Organism=Escherichia coli, GI1789647, Length=152, Percent_Identity=28.9473684210526, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007227 [H]

Pfam domain/function: PF04093 MreD [H]

EC number: NA

Molecular weight: Translated: 21171; Mature: 21171

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPRQNGKSRIRRYDYEIQEFLFPARKSLIYISLITAVLINLMPFDKVILVLRPDFVALT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEECCHHHHHH
LLYWNIYQPQQAGMSIAFISGLFMDVIDVSIMGQHAIAYCLITFFALILYRRLRLFNAFQ
HHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIPAVLWILLSGQGVVFLTGILAGSYIPEWYIFLASVTGALCWPLLVFLLGIFRKQRIDR
HHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DEV
CCC
>Mature Secondary Structure
MHPRQNGKSRIRRYDYEIQEFLFPARKSLIYISLITAVLINLMPFDKVILVLRPDFVALT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEECCHHHHHH
LLYWNIYQPQQAGMSIAFISGLFMDVIDVSIMGQHAIAYCLITFFALILYRRLRLFNAFQ
HHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIPAVLWILLSGQGVVFLTGILAGSYIPEWYIFLASVTGALCWPLLVFLLGIFRKQRIDR
HHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DEV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]