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The map label for this gene is serC [H]

Identifier: 114331559

GI number: 114331559

Start: 1648044

End: 1649150

Strand: Reverse

Name: serC [H]

Synonym: Neut_1572

Alternate gene names: 114331559

Gene position: 1649150-1648044 (Counterclockwise)

Preceding gene: 114331560

Following gene: 114331558

Centisome position: 61.97

GC content: 49.05

Gene sequence:

>1107_bases
ATGAGGAAAATATACAATTTCAGTGCAGGACCGGCTGTTTTGCCGGAGGAAGTATTGGAACAGGCTCGCGAGGAAATGCT
GGACTGGCATGGTAGTGGCATGTCGGTCATGGAGATGAGTCATCGCGGGAAAGAATTCATGTCCATAGTAGATAAAGCCG
AATCCGATTTGCGTGAGTTGGCGAATATTCCCGCTAACTACAAAGTACTCTTTCTTCAGGGAGGGGCGTCCAGTCAGTTT
GCCGTGGTGCCGATGAATCTGCTTGAAGGAAATACTCAAGCAGATTATGTTCATACCGGCCAATGGTCAAAAAAAGCCGC
CTCTGAGGCGGGTCAATACTGCTCTGTTCATATCACTGCATCATCGGAACAAGATGGCTTCAACTCCGTTCCCCCGCTGG
AACAATGGCATATTTCATCTGATACAGCCTATGTGCACTATACGCCCAACGAAACGATCGGTGGAGTTGAATTCCAGTGG
ACGCCTGATTTATCTGTGGCCCCTGGTGGCAATGGCAATATTCCCTTGGTCGCTGATATGTCGTCCAATTTCCTGTCGCG
GCCATTTGATGTCAGTAAATTCGGGTTGATTTACGCCGGAGCACAGAAAAATGTGGGCCCGGCCGGGCTGGTGATCGTGA
TTATCCGAGAAGATTTGCTGGCTATTCCGCCGCTTCCCCGGACTCCCACCATGTACCGCTACAAAACGCATGCGGATCAG
GCCTCAATGTACAATACACCGCCCACTTATGCCATTTACATCATGGGGCTGGTCATGGAATGGTTAAAAAAACAGGGTGG
ATTGGTTGCGATCGAACAGCGTAATATCGCCAAGGCTAAACTGATCTATGATCTGATTGATGCTAGTAGTTTCTACCATT
GTCCGGTCAGCCGATCAGATCGATCGAGGATGAATATTCCATTCACACTAAGTGATTCCGGTCTTGATGAGGTATTCCTG
AAACAGGCGCAGGCACATGGATTGCTTCAGTTGAAAGGGCACCGATCAGTCGGTGGCATGCGTGCTTCAATCTATAATGC
CATGCCATTGGAAGGGGTGCAGACACTGGCGACATTCATGCGGGAATTTGAGAAAAACCATGTCTGA

Upstream 100 bases:

>100_bases
CTCAGGGGGTTATACTGATTAATCTGGATGCCGGCGAGAAACTTGCTGGACTGGAAAGAATCGTTGAAACGGATGAGAAC
TAATTCAACCCGGTGACACA

Downstream 100 bases:

>100_bases
AGATATTCAGAAAATCTGCAAAGTTCTTACGCTAAACTCGATTGCTTCGGTCGGACTCAAGCGTTTACCTGCCAATATTT
TTCAGATCAGTAGTGATATT

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MRKIYNFSAGPAVLPEEVLEQAREEMLDWHGSGMSVMEMSHRGKEFMSIVDKAESDLRELANIPANYKVLFLQGGASSQF
AVVPMNLLEGNTQADYVHTGQWSKKAASEAGQYCSVHITASSEQDGFNSVPPLEQWHISSDTAYVHYTPNETIGGVEFQW
TPDLSVAPGGNGNIPLVADMSSNFLSRPFDVSKFGLIYAGAQKNVGPAGLVIVIIREDLLAIPPLPRTPTMYRYKTHADQ
ASMYNTPPTYAIYIMGLVMEWLKKQGGLVAIEQRNIAKAKLIYDLIDASSFYHCPVSRSDRSRMNIPFTLSDSGLDEVFL
KQAQAHGLLQLKGHRSVGGMRASIYNAMPLEGVQTLATFMREFEKNHV

Sequences:

>Translated_368_residues
MRKIYNFSAGPAVLPEEVLEQAREEMLDWHGSGMSVMEMSHRGKEFMSIVDKAESDLRELANIPANYKVLFLQGGASSQF
AVVPMNLLEGNTQADYVHTGQWSKKAASEAGQYCSVHITASSEQDGFNSVPPLEQWHISSDTAYVHYTPNETIGGVEFQW
TPDLSVAPGGNGNIPLVADMSSNFLSRPFDVSKFGLIYAGAQKNVGPAGLVIVIIREDLLAIPPLPRTPTMYRYKTHADQ
ASMYNTPPTYAIYIMGLVMEWLKKQGGLVAIEQRNIAKAKLIYDLIDASSFYHCPVSRSDRSRMNIPFTLSDSGLDEVFL
KQAQAHGLLQLKGHRSVGGMRASIYNAMPLEGVQTLATFMREFEKNHV
>Mature_368_residues
MRKIYNFSAGPAVLPEEVLEQAREEMLDWHGSGMSVMEMSHRGKEFMSIVDKAESDLRELANIPANYKVLFLQGGASSQF
AVVPMNLLEGNTQADYVHTGQWSKKAASEAGQYCSVHITASSEQDGFNSVPPLEQWHISSDTAYVHYTPNETIGGVEFQW
TPDLSVAPGGNGNIPLVADMSSNFLSRPFDVSKFGLIYAGAQKNVGPAGLVIVIIREDLLAIPPLPRTPTMYRYKTHADQ
ASMYNTPPTYAIYIMGLVMEWLKKQGGLVAIEQRNIAKAKLIYDLIDASSFYHCPVSRSDRSRMNIPFTLSDSGLDEVFL
KQAQAHGLLQLKGHRSVGGMRASIYNAMPLEGVQTLATFMREFEKNHV

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=373, Percent_Identity=48.5254691689008, Blast_Score=366, Evalue=1e-101,
Organism=Homo sapiens, GI10863955, Length=368, Percent_Identity=42.9347826086957, Blast_Score=307, Evalue=1e-83,
Organism=Escherichia coli, GI1787136, Length=368, Percent_Identity=52.9891304347826, Blast_Score=415, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17506897, Length=371, Percent_Identity=48.2479784366577, Blast_Score=344, Evalue=5e-95,
Organism=Saccharomyces cerevisiae, GI6324758, Length=388, Percent_Identity=39.9484536082474, Blast_Score=264, Evalue=1e-71,
Organism=Drosophila melanogaster, GI21356589, Length=369, Percent_Identity=50.9485094850949, Blast_Score=385, Evalue=1e-107,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 40728; Mature: 40728

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIYNFSAGPAVLPEEVLEQAREEMLDWHGSGMSVMEMSHRGKEFMSIVDKAESDLREL
CCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHH
ANIPANYKVLFLQGGASSQFAVVPMNLLEGNTQADYVHTGQWSKKAASEAGQYCSVHITA
HCCCCCEEEEEEECCCCCCEEEEEHHHHCCCCCCCEEECCCCHHHHHHHCCCEEEEEEEE
SSEQDGFNSVPPLEQWHISSDTAYVHYTPNETIGGVEFQWTPDLSVAPGGNGNIPLVADM
CCCCCCCCCCCCHHHEECCCCEEEEEECCCCCCCCEEEEECCCCEECCCCCCCCCEEECC
SSNFLSRPFDVSKFGLIYAGAQKNVGPAGLVIVIIREDLLAIPPLPRTPTMYRYKTHADQ
CCCHHCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCHHCCCCCCCCCCEEEEECCCCC
ASMYNTPPTYAIYIMGLVMEWLKKQGGLVAIEQRNIAKAKLIYDLIDASSFYHCPVSRSD
CCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCEEECCCCCCC
RSRMNIPFTLSDSGLDEVFLKQAQAHGLLQLKGHRSVGGMRASIYNAMPLEGVQTLATFM
CCCCCCCEEECCCCHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHH
REFEKNHV
HHHHHCCC
>Mature Secondary Structure
MRKIYNFSAGPAVLPEEVLEQAREEMLDWHGSGMSVMEMSHRGKEFMSIVDKAESDLREL
CCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHH
ANIPANYKVLFLQGGASSQFAVVPMNLLEGNTQADYVHTGQWSKKAASEAGQYCSVHITA
HCCCCCEEEEEEECCCCCCEEEEEHHHHCCCCCCCEEECCCCHHHHHHHCCCEEEEEEEE
SSEQDGFNSVPPLEQWHISSDTAYVHYTPNETIGGVEFQWTPDLSVAPGGNGNIPLVADM
CCCCCCCCCCCCHHHEECCCCEEEEEECCCCCCCCEEEEECCCCEECCCCCCCCCEEECC
SSNFLSRPFDVSKFGLIYAGAQKNVGPAGLVIVIIREDLLAIPPLPRTPTMYRYKTHADQ
CCCHHCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCHHCCCCCCCCCCEEEEECCCCC
ASMYNTPPTYAIYIMGLVMEWLKKQGGLVAIEQRNIAKAKLIYDLIDASSFYHCPVSRSD
CCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCEEECCCCCCC
RSRMNIPFTLSDSGLDEVFLKQAQAHGLLQLKGHRSVGGMRASIYNAMPLEGVQTLATFM
CCCCCCCEEECCCCHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHH
REFEKNHV
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]