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The map label for this gene is fppS [H]

Identifier: 114331488

GI number: 114331488

Start: 1570368

End: 1571261

Strand: Direct

Name: fppS [H]

Synonym: Neut_1500

Alternate gene names: 114331488

Gene position: 1570368-1571261 (Clockwise)

Preceding gene: 114331487

Following gene: 114331489

Centisome position: 59.01

GC content: 49.78

Gene sequence:

>894_bases
ATGCACCCTGATTTCCAGCTGTGGACAACTGAGCGCCTTGCTTTAATTGAATCTTTCTTGGAGCAGAATCTTCCTGCCAC
GAATTGTGCCCCTGCACGCTTGCATGAAGCAATGCGTTACGCGGTACTAAATGGGGGTAAGCGAGTACGGCCACTACTAT
CCTTTGCCGCCGGGGAACTTAGTGGAGCTGATAAAACACAAGTCATTGCTGCCAGCGCGGCAGTGGAATTGATCCATGCC
TACTCCCTGGTGCATGATGATCTTCCCTGTATGGATAATGACATACTCCGGCGCGGCAAACCAACCTGCCATATCAGATA
TGGCGAACCTACCGCCTTGCTGGTGGGAGATAGCCTGCAAAGTCTGGCTTTTCAGTTATTAGCTGAATCTGCTTTAACTG
AAGATCCACGTACACAGCTGGAAATGATTCGGCATCTTGCATTCGCTGCCGGATCCCGAGGTATGGCTGGAGGACAGGCA
ATTGACTTGGATAGTGTTGGCAAAACACTCAGCCTTCCGGAACTCGAATTCATGCACATTCACAAAACTGGTGCACTGAT
CCGGGCTGCAGTAATACTTGGAGCCCGTTGCGGTAGCAGACTGAATGAAGATCAATTTAAACAGTTGGACCATTTTGCCA
AGTGTATCGGTCTGGCATTTCAGGTAGTAGATGATATTCTCGATGCAGAAGCCTCCACTGCTGCGCTAGGCAAAACCGCA
GGGAAGGATGCAGAAAACAACAAACCTACCTATGTTAGTATACTGGGTATCAAACAAGCCCGAGAACTGGCGCACGAGCT
TCAGCGGGAAGCCAGCGGGGTGCTGGACAAATTTGGTCCTGAAGCCCTGCGTTTGCAGCAAATCACTGATTTCATTGTAC
AGCGTGAGTTTTAG

Upstream 100 bases:

>100_bases
GAATTGTTACAATACTGCCAGAATATGCTGAAAGACTCGCAGCAACAGATAAAAATACTTGAAGCAGACATATTGAAAAA
TTTTTCTACTACCGAGCACG

Downstream 100 bases:

>100_bases
TTTTACGCTACCAATCCAATCTTTACCAATCTTTACGTTACCCACTCTTAGCTACAATTCGCATGTATCCATTACTCGAT
CGCATTGAGATACCCGCACA

Product: polyprenyl synthetase

Products: NA

Alternate protein names: FPP synthase; (2E,6E)-farnesyl diphosphate synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MHPDFQLWTTERLALIESFLEQNLPATNCAPARLHEAMRYAVLNGGKRVRPLLSFAAGELSGADKTQVIAASAAVELIHA
YSLVHDDLPCMDNDILRRGKPTCHIRYGEPTALLVGDSLQSLAFQLLAESALTEDPRTQLEMIRHLAFAAGSRGMAGGQA
IDLDSVGKTLSLPELEFMHIHKTGALIRAAVILGARCGSRLNEDQFKQLDHFAKCIGLAFQVVDDILDAEASTAALGKTA
GKDAENNKPTYVSILGIKQARELAHELQREASGVLDKFGPEALRLQQITDFIVQREF

Sequences:

>Translated_297_residues
MHPDFQLWTTERLALIESFLEQNLPATNCAPARLHEAMRYAVLNGGKRVRPLLSFAAGELSGADKTQVIAASAAVELIHA
YSLVHDDLPCMDNDILRRGKPTCHIRYGEPTALLVGDSLQSLAFQLLAESALTEDPRTQLEMIRHLAFAAGSRGMAGGQA
IDLDSVGKTLSLPELEFMHIHKTGALIRAAVILGARCGSRLNEDQFKQLDHFAKCIGLAFQVVDDILDAEASTAALGKTA
GKDAENNKPTYVSILGIKQARELAHELQREASGVLDKFGPEALRLQQITDFIVQREF
>Mature_297_residues
MHPDFQLWTTERLALIESFLEQNLPATNCAPARLHEAMRYAVLNGGKRVRPLLSFAAGELSGADKTQVIAASAAVELIHA
YSLVHDDLPCMDNDILRRGKPTCHIRYGEPTALLVGDSLQSLAFQLLAESALTEDPRTQLEMIRHLAFAAGSRGMAGGQA
IDLDSVGKTLSLPELEFMHIHKTGALIRAAVILGARCGSRLNEDQFKQLDHFAKCIGLAFQVVDDILDAEASTAALGKTA
GKDAENNKPTYVSILGIKQARELAHELQREASGVLDKFGPEALRLQQITDFIVQREF

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786623, Length=265, Percent_Identity=49.0566037735849, Blast_Score=220, Evalue=8e-59,
Organism=Escherichia coli, GI1789578, Length=217, Percent_Identity=31.3364055299539, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.10 [H]

Molecular weight: Translated: 32408; Mature: 32408

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPDFQLWTTERLALIESFLEQNLPATNCAPARLHEAMRYAVLNGGKRVRPLLSFAAGEL
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
SGADKTQVIAASAAVELIHAYSLVHDDLPCMDNDILRRGKPTCHIRYGEPTALLVGDSLQ
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEECCCEEEEECCHHH
SLAFQLLAESALTEDPRTQLEMIRHLAFAAGSRGMAGGQAIDLDSVGKTLSLPELEFMHI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCEECHHHCCCCCCCCCCHHEEE
HKTGALIRAAVILGARCGSRLNEDQFKQLDHFAKCIGLAFQVVDDILDAEASTAALGKTA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCC
GKDAENNKPTYVSILGIKQARELAHELQREASGVLDKFGPEALRLQQITDFIVQREF
CCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHPDFQLWTTERLALIESFLEQNLPATNCAPARLHEAMRYAVLNGGKRVRPLLSFAAGEL
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
SGADKTQVIAASAAVELIHAYSLVHDDLPCMDNDILRRGKPTCHIRYGEPTALLVGDSLQ
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEECCCEEEEECCHHH
SLAFQLLAESALTEDPRTQLEMIRHLAFAAGSRGMAGGQAIDLDSVGKTLSLPELEFMHI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCEECHHHCCCCCCCCCCHHEEE
HKTGALIRAAVILGARCGSRLNEDQFKQLDHFAKCIGLAFQVVDDILDAEASTAALGKTA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCC
GKDAENNKPTYVSILGIKQARELAHELQREASGVLDKFGPEALRLQQITDFIVQREF
CCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9655913; 12597275 [H]