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The map label for this gene is ilvH [H]

Identifier: 114331256

GI number: 114331256

Start: 1316990

End: 1317481

Strand: Reverse

Name: ilvH [H]

Synonym: Neut_1261

Alternate gene names: 114331256

Gene position: 1317481-1316990 (Counterclockwise)

Preceding gene: 114331257

Following gene: 114331255

Centisome position: 49.51

GC content: 43.09

Gene sequence:

>492_bases
ATGCGACATATTATTTCTTTGTTAATGGAAAATGAGGCTGGCGCACTATCGCGAGTAGCCGGTTTGTTTTCTGCTCGTGG
TTACAATATTGAATCCCTATCTGTTGCTCCTACTGAGGATCCGACGTTGTCTCGTATGACTCTGGTCACGAATGGCCCTG
AAGAAATTGTCGAACAGATTACTAAGCAGCTCAATAAGTTGATTGAAGTTGTCAAGCTGATTGATTTGAGCGATGAAGGT
TATGTTGAGCGAGAACTCATGTTGATAAAGGTAAGGGCGGTGGATAAGGATCGTGAGGAGATGAAGCGACTCGTTGATAT
ATTTCGGGGTAATATCATTGATGTTACAAATAAAATCTACACCATAGAACTTACGGGTACCAGAGCAAAACTGGATGGTT
TCTTGCAGGCAATAGATCGCAATCTGATTCTGGAGATAGCCAGAACAGGTGTGTCCGGTCTCGGCCGTGGAGAACGGATT
TTAGAACTATAA

Upstream 100 bases:

>100_bases
CAGCTTGTATTCATAGACTTTATTACAGACCAGACCGAGAACGTTTTTCCTATGGTGCCTGGTGGAAAAGGTCTATCCGA
AATGATTTTGGTATAACAGT

Downstream 100 bases:

>100_bases
ATTTTTTACCGGGATCTGTCGGTAGATTCTGATTTCATCGATAGCTCATCTGTCGATGTGGCTGCATAAACACTCAGGAA
GGAAAATAATGAAAGTCTAT

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: ALS-III; Acetohydroxy-acid synthase III small subunit; AHAS-III [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MRHIISLLMENEAGALSRVAGLFSARGYNIESLSVAPTEDPTLSRMTLVTNGPEEIVEQITKQLNKLIEVVKLIDLSDEG
YVERELMLIKVRAVDKDREEMKRLVDIFRGNIIDVTNKIYTIELTGTRAKLDGFLQAIDRNLILEIARTGVSGLGRGERI
LEL

Sequences:

>Translated_163_residues
MRHIISLLMENEAGALSRVAGLFSARGYNIESLSVAPTEDPTLSRMTLVTNGPEEIVEQITKQLNKLIEVVKLIDLSDEG
YVERELMLIKVRAVDKDREEMKRLVDIFRGNIIDVTNKIYTIELTGTRAKLDGFLQAIDRNLILEIARTGVSGLGRGERI
LEL
>Mature_163_residues
MRHIISLLMENEAGALSRVAGLFSARGYNIESLSVAPTEDPTLSRMTLVTNGPEEIVEQITKQLNKLIEVVKLIDLSDEG
YVERELMLIKVRAVDKDREEMKRLVDIFRGNIIDVTNKIYTIELTGTRAKLDGFLQAIDRNLILEIARTGVSGLGRGERI
LEL

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=162, Percent_Identity=58.641975308642, Blast_Score=192, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6319837, Length=204, Percent_Identity=27.9411764705882, Blast_Score=88, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 18295; Mature: 18295

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHIISLLMENEAGALSRVAGLFSARGYNIESLSVAPTEDPTLSRMTLVTNGPEEIVEQI
CHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEECCHHHHHHHH
TKQLNKLIEVVKLIDLSDEGYVERELMLIKVRAVDKDREEMKRLVDIFRGNIIDVTNKIY
HHHHHHHHHHHHHHCCCCCCCEEHHEEEEEEECCCCCHHHHHHHHHHHCCCEEEECCEEE
TIELTGTRAKLDGFLQAIDRNLILEIARTGVSGLGRGERILEL
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRHIISLLMENEAGALSRVAGLFSARGYNIESLSVAPTEDPTLSRMTLVTNGPEEIVEQI
CHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEECCHHHHHHHH
TKQLNKLIEVVKLIDLSDEGYVERELMLIKVRAVDKDREEMKRLVDIFRGNIIDVTNKIY
HHHHHHHHHHHHHHCCCCCCCEEHHEEEEEEECCCCCHHHHHHHHHHHCCCEEEECCEEE
TIELTGTRAKLDGFLQAIDRNLILEIARTGVSGLGRGERILEL
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6308579; 1630901; 9278503; 1851954; 2198273 [H]