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The map label for this gene is fbaA [H]

Identifier: 113477519

GI number: 113477519

Start: 6321624

End: 6322703

Strand: Reverse

Name: fbaA [H]

Synonym: Tery_4099

Alternate gene names: 113477519

Gene position: 6322703-6321624 (Counterclockwise)

Preceding gene: 113477521

Following gene: 113477516

Centisome position: 81.58

GC content: 41.67

Gene sequence:

>1080_bases
ATGGCTATTGTACCAATGCGTTTACTACTAGACCACGCAGCAGAAAACGGTTATGGCATCCCTGCATATAATGTCAACAA
CATGGAGCAAATTCAGTCCATTATGCAGGCCGCAGAGGAAGCAGACAGCCCTGTAATTCTCCAAGCTTCTCGTGGAGCTC
GCAAATATGCTGGTGAAAATTTCCTACGTCACTTAATTTTGGCTGCAGTAGAGACTTACCCTCATCTTCCCATTGCTATG
CACCAGGATCATGGTAATGCACCCTCTACTTGCTATTCTGCTATGCGCCATGGTTTCACTAGCGTAATGATGGATGGTTC
TCTAGAGGCAGACGGTAAAACTCCAGCTAGCTTTGAATATAATGTTAATGTTACTAGTGAAGTAGTTAAAGTTGCTCACT
CCATTGGAGTAAGTGTAGAAGGTGAGTTAGGTTGTTTAGGTTCCTTGGAAACTGGTATGGGAGATAAGGAAGATGGTCAT
GGAGCAGAAGGTAAGCTTTCCCACGACCAACTTTTAACAGATCCAGATGAAGCTGTTCAATTTGTAGAACAAACCCAAGT
AGATGCTCTAGCAGTTGCTATTGGTACTAGCCATGGAGCTTACAAGTTTACCCGTAAACCTACAGGAGAAATTTTAGCTA
TTAGCCGAATTGAAGAAATTCATCGTCGCTTACCTAATACTCACTTAGTGATGCACGGGTCTTCTTCTGTACCTGAAGAT
TTGTTGGCAATTATTAACGAGTATGGTGGTAAGATTCCAGAAACTTACGGTGTGCCTGTTGAAGAAATTCAAAAAGGAAT
CAAGAGTGGTGTTCGTAAGGTGAATATTGATACTGATAATCGCTTGGCCATTACTGCTGCTATTCGTGAAGCTGCTGCTA
AAGATCCTTCTAACTTTGACCCTCGTCATTTCTTGAAGCCTTCTATCAAGTATATGAAGCAAGTATGTCTAGATCGTTAT
CAACAGTTTGGTACTGCTGGTAATGCTAGTAAGATTAAGGTTCAAACTTTAGATGAGTTTGCTGATAGATATGCTCGTGG
AGAATTAGCTGCTACTACTAAGACAGCAGTTGCAGTATAG

Upstream 100 bases:

>100_bases
TCTTCAATTTGTCTTAATATTATCGTAAGAATTAAGCTTAGGTAAATCAAGTTACTAATAAGCTAATAATAATAACAAAA
GGATATTAGGAGGAAAAGGT

Downstream 100 bases:

>100_bases
TTTGTAGCAAAATTATAATTTTTATTCCAAGTTCTTAATTATCTAATTAATTTAATTAGTTGATCAGAAGTTCTTGAATT
GATATCATCCCGACGCTGTT

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase; Fructose-bisphosphate aldolase class II [H]

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MAIVPMRLLLDHAAENGYGIPAYNVNNMEQIQSIMQAAEEADSPVILQASRGARKYAGENFLRHLILAAVETYPHLPIAM
HQDHGNAPSTCYSAMRHGFTSVMMDGSLEADGKTPASFEYNVNVTSEVVKVAHSIGVSVEGELGCLGSLETGMGDKEDGH
GAEGKLSHDQLLTDPDEAVQFVEQTQVDALAVAIGTSHGAYKFTRKPTGEILAISRIEEIHRRLPNTHLVMHGSSSVPED
LLAIINEYGGKIPETYGVPVEEIQKGIKSGVRKVNIDTDNRLAITAAIREAAAKDPSNFDPRHFLKPSIKYMKQVCLDRY
QQFGTAGNASKIKVQTLDEFADRYARGELAATTKTAVAV

Sequences:

>Translated_359_residues
MAIVPMRLLLDHAAENGYGIPAYNVNNMEQIQSIMQAAEEADSPVILQASRGARKYAGENFLRHLILAAVETYPHLPIAM
HQDHGNAPSTCYSAMRHGFTSVMMDGSLEADGKTPASFEYNVNVTSEVVKVAHSIGVSVEGELGCLGSLETGMGDKEDGH
GAEGKLSHDQLLTDPDEAVQFVEQTQVDALAVAIGTSHGAYKFTRKPTGEILAISRIEEIHRRLPNTHLVMHGSSSVPED
LLAIINEYGGKIPETYGVPVEEIQKGIKSGVRKVNIDTDNRLAITAAIREAAAKDPSNFDPRHFLKPSIKYMKQVCLDRY
QQFGTAGNASKIKVQTLDEFADRYARGELAATTKTAVAV
>Mature_358_residues
AIVPMRLLLDHAAENGYGIPAYNVNNMEQIQSIMQAAEEADSPVILQASRGARKYAGENFLRHLILAAVETYPHLPIAMH
QDHGNAPSTCYSAMRHGFTSVMMDGSLEADGKTPASFEYNVNVTSEVVKVAHSIGVSVEGELGCLGSLETGMGDKEDGHG
AEGKLSHDQLLTDPDEAVQFVEQTQVDALAVAIGTSHGAYKFTRKPTGEILAISRIEEIHRRLPNTHLVMHGSSSVPEDL
LAIINEYGGKIPETYGVPVEEIQKGIKSGVRKVNIDTDNRLAITAAIREAAAKDPSNFDPRHFLKPSIKYMKQVCLDRYQ
QFGTAGNASKIKVQTLDEFADRYARGELAATTKTAVAV

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=331, Percent_Identity=34.441087613293, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI87082041, Length=329, Percent_Identity=32.5227963525836, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1788072, Length=329, Percent_Identity=29.483282674772, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789293, Length=308, Percent_Identity=24.3506493506494, Blast_Score=71, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6322790, Length=322, Percent_Identity=26.3975155279503, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006412
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 38956; Mature: 38824

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIVPMRLLLDHAAENGYGIPAYNVNNMEQIQSIMQAAEEADSPVILQASRGARKYAGEN
CCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHH
FLRHLILAAVETYPHLPIAMHQDHGNAPSTCYSAMRHGFTSVMMDGSLEADGKTPASFEY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCEEE
NVNVTSEVVKVAHSIGVSVEGELGCLGSLETGMGDKEDGHGAEGKLSHDQLLTDPDEAVQ
ECCHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
FVEQTQVDALAVAIGTSHGAYKFTRKPTGEILAISRIEEIHRRLPNTHLVMHGSSSVPED
HHHHHHHHHEEEEEECCCCCEEECCCCCCCEEHHHHHHHHHHHCCCCEEEEECCCCCHHH
LLAIINEYGGKIPETYGVPVEEIQKGIKSGVRKVNIDTDNRLAITAAIREAAAKDPSNFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCEEHHHHHHHHHCCCCCCCC
PRHFLKPSIKYMKQVCLDRYQQFGTAGNASKIKVQTLDEFADRYARGELAATTKTAVAV
CHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCHHHCCHHHHCC
>Mature Secondary Structure 
AIVPMRLLLDHAAENGYGIPAYNVNNMEQIQSIMQAAEEADSPVILQASRGARKYAGEN
CCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHH
FLRHLILAAVETYPHLPIAMHQDHGNAPSTCYSAMRHGFTSVMMDGSLEADGKTPASFEY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCEEE
NVNVTSEVVKVAHSIGVSVEGELGCLGSLETGMGDKEDGHGAEGKLSHDQLLTDPDEAVQ
ECCHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
FVEQTQVDALAVAIGTSHGAYKFTRKPTGEILAISRIEEIHRRLPNTHLVMHGSSSVPED
HHHHHHHHHEEEEEECCCCCEEECCCCCCCEEHHHHHHHHHHHCCCCEEEEECCCCCHHH
LLAIINEYGGKIPETYGVPVEEIQKGIKSGVRKVNIDTDNRLAITAAIREAAAKDPSNFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCEEHHHHHHHHHCCCCCCCC
PRHFLKPSIKYMKQVCLDRYQQFGTAGNASKIKVQTLDEFADRYARGELAATTKTAVAV
CHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9298645 [H]