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The map label for this gene is capA [H]

Identifier: 113477521

GI number: 113477521

Start: 6325134

End: 6326900

Strand: Reverse

Name: capA [H]

Synonym: Tery_4101

Alternate gene names: 113477521

Gene position: 6326900-6325134 (Counterclockwise)

Preceding gene: 113477523

Following gene: 113477519

Centisome position: 81.64

GC content: 33.56

Gene sequence:

>1767_bases
ATGAATTACATACCTAATTTGACTCAAAAATCTCTTTTTGAATTAGCAAGTTCCGGTGATTTTCAGGCAATTAGTCAATG
GATTAATAAAAAACTTAAACCTCAAGGAATTTCAGCTCGTATAGCTAAAGAAAATACTGGATATCTAGAAGTTTTAGTAG
AGTTTCAGACTCAACCTCCTGTAGATAGATTAATTAAGTTTATCTGTTATCAACTTTCTCAACTTAACTATCCTACACTA
GAAAAAGTAAAAATTGTGGGGCGTTTAAGTGGTTCACCTAATATACTATGGAAACACTCTGTCAGAATTAATTCTCATGC
AAAAAAAAATTTCAATAAGCAATCTAATTTTGTAAACAAAAGTGATAATTTGCAATTTCAAACATTTCGTTATTTGATCT
TACTCAGTTCAGCGGTTGCAGCTTTCATTATAGGTATTTTAGTAAGTTATTATAGTGTTTTGGTACGAAATTCAACCTCA
GGTCAATGGGTAGAAACTGCTATAGAAAAGGTGAGAGTTGTGGAGCATAGAAAGGTACAAAACTCCCAGGATCCTATGGT
GACTTTAATGTTTGGTGGAGATGTTAATTTATCTAACCAAGTTTCTAATTTAGTAAAGAGAGATTATAAGTTACCTTTTG
CTAAAATGAATGAGTATAGGGCTGCAGACTTATCAATAGTTAACCTGGAAAGTCCTTTGACCCGTTCTACTCTCAACAGT
AGAACTCAGCAACAAAAATCAACGGTAAATCCTAGTTATGTTAAGGCATTAACCTCAGGAGGAGTTGATCTGGTAAATTT
AGCTAATGACCATACTTTGGGTTATGAGCAAAAAAGTTTGTTAGAGACAATAGAAACTTTAGAGAATGCGGGTATTCATT
CTTTAGGAGCGGGCAAAACAGAAGAAGAGGCTAGAAGGCCAAAAATTTTTGAAGTTAAAGGCCAAAAGATTGCATATCTC
AATTACTATGATACAGATATTCAACCAACTACTGAATCAGTATATGTAAATAGTCGGAATAAGGATAGGCTCTCTTCAGA
TATTCAAATTTTGAAGAAGCAGGTAGACTGGATAATTGTTAATTATCATTGGGGGGTTCAACTCTCAGAATATCCTGGAG
ATTGGCAGATGAATATAGCGAGGATGACAATTGACCAAGGTGCTGATTTGGTAGTAGGACATCATCCTAAAGTATTGCAG
GGGGCAGAAATTTATCGGGGACGACCTATTATATATTCTTTGGGAAATTTTATTTTTGGAGACACTTCTAACAAAGAGAG
TGATTATGACACAGCAGTTTTGAAGGTATCTTTAAAACCAGGAAAAATGAAGATTGAGTTTTTGCCTGTAGTGGTTAGTA
AGTACCAACCCCACATTGTCAAAGGTGAAAAAGGTAAAGAAATTCTTAAACACATTGCTCAAATTTCTAGTATTTTTCAC
CAGCCAATGAGAACTCCTATAATAATAAATACGATAAATGATGATTTTAATTTTGTTGGTATTGACTCTTTTCCTAGGGA
AGAAAATTCTAAAACTTTCTCAACTCCAATTTTACCTGAGTTACCTCTAAAATCTCCACAAGCTGATCCAAATCCTACAA
GCTCTTCTCATAATAATTCAGAGCAAGAAGCAAGTAATAATAATAATAGCTTTTCTTTACCACCAATATTAAGTCCTGCA
CCCACTCCTAAAGAAAGAATAGATCCTTTCATTAAAAAGCCATTTATCAAAGAACCTTTTATTGAATTGCCTCGTTTACA
AATTTAA

Upstream 100 bases:

>100_bases
GGCAAATTTTATAGTTATACAAACATGATTTCTTTGCTTCTATAACTTAAAGATAAGTTGGTGAATACAACAAGTTGAAA
AACTTTACAATATCTAAAAT

Downstream 100 bases:

>100_bases
TTAAGGTTATACAAATATCAAAAACTAACTGCTAGTAGTCCTACTCTTTGTGTTTTGTTATTCTCAAAAGTAGAAGAGAT
GTGTAATGAATTTGGCACTA

Product: poly-gamma-glutamate biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MNYIPNLTQKSLFELASSGDFQAISQWINKKLKPQGISARIAKENTGYLEVLVEFQTQPPVDRLIKFICYQLSQLNYPTL
EKVKIVGRLSGSPNILWKHSVRINSHAKKNFNKQSNFVNKSDNLQFQTFRYLILLSSAVAAFIIGILVSYYSVLVRNSTS
GQWVETAIEKVRVVEHRKVQNSQDPMVTLMFGGDVNLSNQVSNLVKRDYKLPFAKMNEYRAADLSIVNLESPLTRSTLNS
RTQQQKSTVNPSYVKALTSGGVDLVNLANDHTLGYEQKSLLETIETLENAGIHSLGAGKTEEEARRPKIFEVKGQKIAYL
NYYDTDIQPTTESVYVNSRNKDRLSSDIQILKKQVDWIIVNYHWGVQLSEYPGDWQMNIARMTIDQGADLVVGHHPKVLQ
GAEIYRGRPIIYSLGNFIFGDTSNKESDYDTAVLKVSLKPGKMKIEFLPVVVSKYQPHIVKGEKGKEILKHIAQISSIFH
QPMRTPIIINTINDDFNFVGIDSFPREENSKTFSTPILPELPLKSPQADPNPTSSSHNNSEQEASNNNNSFSLPPILSPA
PTPKERIDPFIKKPFIKEPFIELPRLQI

Sequences:

>Translated_588_residues
MNYIPNLTQKSLFELASSGDFQAISQWINKKLKPQGISARIAKENTGYLEVLVEFQTQPPVDRLIKFICYQLSQLNYPTL
EKVKIVGRLSGSPNILWKHSVRINSHAKKNFNKQSNFVNKSDNLQFQTFRYLILLSSAVAAFIIGILVSYYSVLVRNSTS
GQWVETAIEKVRVVEHRKVQNSQDPMVTLMFGGDVNLSNQVSNLVKRDYKLPFAKMNEYRAADLSIVNLESPLTRSTLNS
RTQQQKSTVNPSYVKALTSGGVDLVNLANDHTLGYEQKSLLETIETLENAGIHSLGAGKTEEEARRPKIFEVKGQKIAYL
NYYDTDIQPTTESVYVNSRNKDRLSSDIQILKKQVDWIIVNYHWGVQLSEYPGDWQMNIARMTIDQGADLVVGHHPKVLQ
GAEIYRGRPIIYSLGNFIFGDTSNKESDYDTAVLKVSLKPGKMKIEFLPVVVSKYQPHIVKGEKGKEILKHIAQISSIFH
QPMRTPIIINTINDDFNFVGIDSFPREENSKTFSTPILPELPLKSPQADPNPTSSSHNNSEQEASNNNNSFSLPPILSPA
PTPKERIDPFIKKPFIKEPFIELPRLQI
>Mature_588_residues
MNYIPNLTQKSLFELASSGDFQAISQWINKKLKPQGISARIAKENTGYLEVLVEFQTQPPVDRLIKFICYQLSQLNYPTL
EKVKIVGRLSGSPNILWKHSVRINSHAKKNFNKQSNFVNKSDNLQFQTFRYLILLSSAVAAFIIGILVSYYSVLVRNSTS
GQWVETAIEKVRVVEHRKVQNSQDPMVTLMFGGDVNLSNQVSNLVKRDYKLPFAKMNEYRAADLSIVNLESPLTRSTLNS
RTQQQKSTVNPSYVKALTSGGVDLVNLANDHTLGYEQKSLLETIETLENAGIHSLGAGKTEEEARRPKIFEVKGQKIAYL
NYYDTDIQPTTESVYVNSRNKDRLSSDIQILKKQVDWIIVNYHWGVQLSEYPGDWQMNIARMTIDQGADLVVGHHPKVLQ
GAEIYRGRPIIYSLGNFIFGDTSNKESDYDTAVLKVSLKPGKMKIEFLPVVVSKYQPHIVKGEKGKEILKHIAQISSIFH
QPMRTPIIINTINDDFNFVGIDSFPREENSKTFSTPILPELPLKSPQADPNPTSSSHNNSEQEASNNNNSFSLPPILSPA
PTPKERIDPFIKKPFIKEPFIELPRLQI

Specific function: Essential for the synthesis of the polyglutamate capsule of B.anthracis which is one of the principal virulence factors during anthrax infection. May form a polyglutamyl synthetase complex together with proteins CapB and CapC [H]

COG id: COG2843

COG function: function code M; Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CapA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019079 [H]

Pfam domain/function: PF09587 PGA_cap [H]

EC number: NA

Molecular weight: Translated: 66482; Mature: 66482

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYIPNLTQKSLFELASSGDFQAISQWINKKLKPQGISARIAKENTGYLEVLVEFQTQPP
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEECCCCC
VDRLIKFICYQLSQLNYPTLEKVKIVGRLSGSPNILWKHSVRINSHAKKNFNKQSNFVNK
HHHHHHHHHHHHHHCCCCCHHHEEEEEEECCCCCEEEEEEEEECCHHHHCCCHHHCCCCC
SDNLQFQTFRYLILLSSAVAAFIIGILVSYYSVLVRNSTSGQWVETAIEKVRVVEHRKVQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
NSQDPMVTLMFGGDVNLSNQVSNLVKRDYKLPFAKMNEYRAADLSIVNLESPLTRSTLNS
CCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEECCCCHHHHHHHH
RTQQQKSTVNPSYVKALTSGGVDLVNLANDHTLGYEQKSLLETIETLENAGIHSLGAGKT
HHHHHHHCCCHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
EEEARRPKIFEVKGQKIAYLNYYDTDIQPTTESVYVNSRNKDRLSSDIQILKKQVDWIIV
HHHHHCCCEEEECCCEEEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEE
NYHWGVQLSEYPGDWQMNIARMTIDQGADLVVGHHPKVLQGAEIYRGRPIIYSLGNFIFG
EEEECEEEECCCCCCEEEEEEEEECCCCCEEECCCCCHHCCCHHHCCCCCEEECCCEEEC
DTSNKESDYDTAVLKVSLKPGKMKIEFLPVVVSKYQPHIVKGEKGKEILKHIAQISSIFH
CCCCCCCCCCEEEEEEEECCCCEEEEEEEEHHHCCCCCEECCCCHHHHHHHHHHHHHHHH
QPMRTPIIINTINDDFNFVGIDSFPREENSKTFSTPILPELPLKSPQADPNPTSSSHNNS
CCCCCCEEEEEECCCCCEEECCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCC
EQEASNNNNSFSLPPILSPAPTPKERIDPFIKKPFIKEPFIELPRLQI
HHHHCCCCCCEECCCCCCCCCCCHHHCCHHHHCCCCCCCHHCCCCCCC
>Mature Secondary Structure
MNYIPNLTQKSLFELASSGDFQAISQWINKKLKPQGISARIAKENTGYLEVLVEFQTQPP
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEECCCCC
VDRLIKFICYQLSQLNYPTLEKVKIVGRLSGSPNILWKHSVRINSHAKKNFNKQSNFVNK
HHHHHHHHHHHHHHCCCCCHHHEEEEEEECCCCCEEEEEEEEECCHHHHCCCHHHCCCCC
SDNLQFQTFRYLILLSSAVAAFIIGILVSYYSVLVRNSTSGQWVETAIEKVRVVEHRKVQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
NSQDPMVTLMFGGDVNLSNQVSNLVKRDYKLPFAKMNEYRAADLSIVNLESPLTRSTLNS
CCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEECCCCHHHHHHHH
RTQQQKSTVNPSYVKALTSGGVDLVNLANDHTLGYEQKSLLETIETLENAGIHSLGAGKT
HHHHHHHCCCHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
EEEARRPKIFEVKGQKIAYLNYYDTDIQPTTESVYVNSRNKDRLSSDIQILKKQVDWIIV
HHHHHCCCEEEECCCEEEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEE
NYHWGVQLSEYPGDWQMNIARMTIDQGADLVVGHHPKVLQGAEIYRGRPIIYSLGNFIFG
EEEECEEEECCCCCCEEEEEEEEECCCCCEEECCCCCHHCCCHHHCCCCCEEECCCEEEC
DTSNKESDYDTAVLKVSLKPGKMKIEFLPVVVSKYQPHIVKGEKGKEILKHIAQISSIFH
CCCCCCCCCCEEEEEEEECCCCEEEEEEEEHHHCCCCCEECCCCHHHHHHHHHHHHHHHH
QPMRTPIIINTINDDFNFVGIDSFPREENSKTFSTPILPELPLKSPQADPNPTSSSHNNS
CCCCCCEEEEEECCCCCEEECCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCC
EQEASNNNNSFSLPPILSPAPTPKERIDPFIKKPFIKEPFIELPRLQI
HHHHCCCCCCEECCCCCCCCCCCHHHCCHHHHCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2536679; 10475962; 12004073 [H]