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The map label for this gene is menA [H]

Identifier: 113477494

GI number: 113477494

Start: 6285411

End: 6286307

Strand: Reverse

Name: menA [H]

Synonym: Tery_4071

Alternate gene names: 113477494

Gene position: 6286307-6285411 (Counterclockwise)

Preceding gene: 113477496

Following gene: 113477493

Centisome position: 81.11

GC content: 33.44

Gene sequence:

>897_bases
ATGACAGCTCAAACAGTAAATAAGTCTGATAAAAAATTATGGTTGGCTGCCATTAAGCCACCTATGTATAGTGTAGCAAT
TATGCCGATATGGATAGGAACAGCAATAGCTATCTGGGAAAAAAATGGGATTGACTGGTCTATTTTTTTAACGTTTATCA
CATCAGCAATTTTAATTTTGGGTTGGGAGAATATTAGTAATGATGTCTTTGACTCGGAGACAGGTATTGATAAAAATAAG
CACCACTCTTTGGTGAATCTAACAGGGAATAAAAACTTAATGTTTTGGTTAGGTAATTTATGTTTATTTTTAGGTATTTT
GGGAGTTGCAACAATTAGCTGGTGGCTGCAAGATTTAACTGTAATTGGATTAATATTACTGTGTTGTTTTTTAGGATATG
TTTATCAAGGTCCTCCTTTCAGATTAGGTTATCAAGGTTTAGGAGAAATTATCTGCTTTTTTGCTTTTGGTCCTTTAGCA
ATTTCTGCTGCTTACTATAGTCAAACTAAGGCTTGGTCAATTACTAGTTTAACGGCTTCAATAATTATTGGAATTACTAC
TACTATTATTCTCTTTTGCTCCCACTTTCATCAGGTAAAAGATGACTTAGCAGCAGGAAAGCGATCGCCTATTGTGAGGA
TGGGAACTAAAGCAGGTTCTCAAGTATTAAATTGGTCTTGCGGAATTGTTTTTGTATTAATTTCTATTTGTGTAGGTTTA
AAACTATTCCCAGTTTGGGCTTTATTAAGTTTTGCTGGCTTGCCTTTTGCTATTCATTTATGTCGTCACCTTAGTCATTA
TCACGACCAACCAGAAAAAATTAGTAACTGTAAATTTATTGCAGTTTATCTACATTTTTTTAGTGGATTATTACTTGGCT
TAGGATTTGTTATTTGA

Upstream 100 bases:

>100_bases
GTTTGGAGTTAGGGTTGATAATTTTATCATAATCAACTTAACTATAACAATCAATTTAACATGACTATTGTTAAAATAAA
GGATTAATTATCAAATTAAT

Downstream 100 bases:

>100_bases
CATATTCTCAGAGCTGAATATTTATAAGTATTCAGTTATCAGTTTGAATAAAAACTGTTATTTTTAAGGTTTTAAAGTCT
TATAGTTACCCTGACATTTT

Product: 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Products: NA

Alternate protein names: DHNA-octaprenyltransferase [H]

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MTAQTVNKSDKKLWLAAIKPPMYSVAIMPIWIGTAIAIWEKNGIDWSIFLTFITSAILILGWENISNDVFDSETGIDKNK
HHSLVNLTGNKNLMFWLGNLCLFLGILGVATISWWLQDLTVIGLILLCCFLGYVYQGPPFRLGYQGLGEIICFFAFGPLA
ISAAYYSQTKAWSITSLTASIIIGITTTIILFCSHFHQVKDDLAAGKRSPIVRMGTKAGSQVLNWSCGIVFVLISICVGL
KLFPVWALLSFAGLPFAIHLCRHLSHYHDQPEKISNCKFIAVYLHFFSGLLLGLGFVI

Sequences:

>Translated_298_residues
MTAQTVNKSDKKLWLAAIKPPMYSVAIMPIWIGTAIAIWEKNGIDWSIFLTFITSAILILGWENISNDVFDSETGIDKNK
HHSLVNLTGNKNLMFWLGNLCLFLGILGVATISWWLQDLTVIGLILLCCFLGYVYQGPPFRLGYQGLGEIICFFAFGPLA
ISAAYYSQTKAWSITSLTASIIIGITTTIILFCSHFHQVKDDLAAGKRSPIVRMGTKAGSQVLNWSCGIVFVLISICVGL
KLFPVWALLSFAGLPFAIHLCRHLSHYHDQPEKISNCKFIAVYLHFFSGLLLGLGFVI
>Mature_297_residues
TAQTVNKSDKKLWLAAIKPPMYSVAIMPIWIGTAIAIWEKNGIDWSIFLTFITSAILILGWENISNDVFDSETGIDKNKH
HSLVNLTGNKNLMFWLGNLCLFLGILGVATISWWLQDLTVIGLILLCCFLGYVYQGPPFRLGYQGLGEIICFFAFGPLAI
SAAYYSQTKAWSITSLTASIIIGITTTIILFCSHFHQVKDDLAAGKRSPIVRMGTKAGSQVLNWSCGIVFVLISICVGLK
LFPVWALLSFAGLPFAIHLCRHLSHYHDQPEKISNCKFIAVYLHFFSGLLLGLGFVI

Specific function: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to dimethylmenaquinone (DMK). Attaches octaprenylpyrophosphate, a membrane-bound 40-carbon side chain to DHNA. The conversion of DHNA to DMK proceeds in three stages:the removal of the carboxyl group of DHNA

COG id: COG1575

COG function: function code H; 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the menA family [H]

Homologues:

Organism=Escherichia coli, GI1790365, Length=285, Percent_Identity=22.8070175438596, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011937
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: =2.5.1.74 [H]

Molecular weight: Translated: 33026; Mature: 32895

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAQTVNKSDKKLWLAAIKPPMYSVAIMPIWIGTAIAIWEKNGIDWSIFLTFITSAILIL
CCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHH
GWENISNDVFDSETGIDKNKHHSLVNLTGNKNLMFWLGNLCLFLGILGVATISWWLQDLT
CCHHCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIGLILLCCFLGYVYQGPPFRLGYQGLGEIICFFAFGPLAISAAYYSQTKAWSITSLTAS
HHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHH
IIIGITTTIILFCSHFHQVKDDLAAGKRSPIVRMGTKAGSQVLNWSCGIVFVLISICVGL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHCCHHHHHHHHHHHHHHH
KLFPVWALLSFAGLPFAIHLCRHLSHYHDQPEKISNCKFIAVYLHFFSGLLLGLGFVI
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TAQTVNKSDKKLWLAAIKPPMYSVAIMPIWIGTAIAIWEKNGIDWSIFLTFITSAILIL
CCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHH
GWENISNDVFDSETGIDKNKHHSLVNLTGNKNLMFWLGNLCLFLGILGVATISWWLQDLT
CCHHCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIGLILLCCFLGYVYQGPPFRLGYQGLGEIICFFAFGPLAISAAYYSQTKAWSITSLTAS
HHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHH
IIIGITTTIILFCSHFHQVKDDLAAGKRSPIVRMGTKAGSQVLNWSCGIVFVLISICVGL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHCCHHHHHHHHHHHHHHH
KLFPVWALLSFAGLPFAIHLCRHLSHYHDQPEKISNCKFIAVYLHFFSGLLLGLGFVI
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]