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The map label for this gene is sdcS [H]

Identifier: 113477404

GI number: 113477404

Start: 6134284

End: 6135711

Strand: Reverse

Name: sdcS [H]

Synonym: Tery_3967

Alternate gene names: 113477404

Gene position: 6135711-6134284 (Counterclockwise)

Preceding gene: 113477406

Following gene: 113477403

Centisome position: 79.17

GC content: 41.81

Gene sequence:

>1428_bases
ATGGAAAATATCAAATATCTTCGTACTTGGTTACGCATATCTCGTCAACCTCAGTACCGTTGGCTTTGGTTTGTAGCCGC
AGCACTAATTTATTTAGGTATTCTTCTGTTTCCAATGGCAGGAGTCGAAAAAGAAGCAAAAGGAGCTTTAGCGGTGTTTG
GAGTCACAGCCTTCCTCTGGGCAACTAATACTCTACCAGTAGCAGTTACAGGCTTGATGGTACTATTTTTAATTCCCCTA
AGTGGCAGTATGTCTGCTACGGACACATACGCCTATTTTGGCAATAAAGCAGTATTCTTTGTATTGGGAGCATTTATTCT
AGCCAGCCCTATTCAACGTTCAGGACTTAGCACTCGTCTGGCTCTCACAGTAGTTTCCCGTTTTGGTAATAGCCAAAATA
CTCTAATTGCCTCTATCTTAATTCTTTCAGCTTTGATGTCTTTTGTAATTAGTTCCTATGCTGTCACAGCTATGTTATTC
CCAGTGGTCATAGAAGTGGTTCAAGCAGCAGGTGCAAAGTCTGGTGGACGTTTTGGTCTAGCAGCATTTTTGGCTTTGGG
GTGGGGTTGCGGTATTGGTGGTATCGCTACTTTACTGGGGGGCGCAAGAGCTCCTCTAGCATTAGGAGTACTTCGCAGCA
CAACAAAAGGAGAATATGATATCACTTTTGTGGAGTGGTTTCTTTGGTCTGTTCCCTTAGTTGTGCTGATGTTAATAGTG
GCTTATCTTGTGCTATTACAAATAGGTAAAGGTATAGTAGTTTCTTTATCTAGTGCCCGAAAGTTTCTTGAAGTTAGATC
GCAAAGTCTTGGGACAATTTCATCTAGGGAAATTGGTACATTAGCGTTAGTGACGGGAATAGTTTTATTATGGGTTTTTA
AGGGAAAAGCTTGGGGACTGGATACAATAGCTTTCTTTGGGGTTATGTGTAGCTTCGTTTGTGGTTTGGCAACTTGGCAA
GAGGTAGAAGAGGATGTTAACTGGGGTATTTTTTTGATGTATGGTAGTGCTATTGCTCTAAGTGCAGTTTTAAGGGATAC
GGGGGCAGCACAAGCATTGGCAGAAAATTTGTTGGGGTCATGGATAAATTCTGGTTTTGTTTGTTTTGTGGCAATGGTTT
TAATTATTACTTTTTTGACGGAGGGAATGAGTAATGCTGCTGCAGTAGCTGTTTTGATGCCAGTGGGACTTGCTTTGGCT
GCTAAATATGGAATAGACCCAAGGGCAATGACGTTGGGTATTACTCTACCATCGGGTTTAGCTTTTCTTTTACCAGTCAG
TACTCCGGTAATGGCTATTATTATGGGTAGTGGTTATGTGTCGCCTGCTGAAGCTTTTAAGCGCGGCTTATTGCTAAAAT
TAGTGGGAACTTTGATCTTCTTGGCAATGGCGAAATTTTATTGGCCTTTATTTGGGTGGGGAGTGTAA

Upstream 100 bases:

>100_bases
AAAAATTTGATTTTTATTTTTTCATTTCCTCTTTTCTGTTCTCTAGTTTTATAAAAAGTATAATCAAATCTCTACGTCAA
AAATTATTCATACATATACA

Downstream 100 bases:

>100_bases
AATATGAGTATCTGGTTAGTAATTGCAAATCCTTACGCTTATGATAAAGCAATGTGGAAAGCAGTTTCAGCAACACAAGA
ACATCAAGGTAATTTGAGGG

Product: anion transporter

Products: tartrate [Cytoplasm]; succinate [Periplasm] [C]

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MENIKYLRTWLRISRQPQYRWLWFVAAALIYLGILLFPMAGVEKEAKGALAVFGVTAFLWATNTLPVAVTGLMVLFLIPL
SGSMSATDTYAYFGNKAVFFVLGAFILASPIQRSGLSTRLALTVVSRFGNSQNTLIASILILSALMSFVISSYAVTAMLF
PVVIEVVQAAGAKSGGRFGLAAFLALGWGCGIGGIATLLGGARAPLALGVLRSTTKGEYDITFVEWFLWSVPLVVLMLIV
AYLVLLQIGKGIVVSLSSARKFLEVRSQSLGTISSREIGTLALVTGIVLLWVFKGKAWGLDTIAFFGVMCSFVCGLATWQ
EVEEDVNWGIFLMYGSAIALSAVLRDTGAAQALAENLLGSWINSGFVCFVAMVLIITFLTEGMSNAAAVAVLMPVGLALA
AKYGIDPRAMTLGITLPSGLAFLLPVSTPVMAIIMGSGYVSPAEAFKRGLLLKLVGTLIFLAMAKFYWPLFGWGV

Sequences:

>Translated_475_residues
MENIKYLRTWLRISRQPQYRWLWFVAAALIYLGILLFPMAGVEKEAKGALAVFGVTAFLWATNTLPVAVTGLMVLFLIPL
SGSMSATDTYAYFGNKAVFFVLGAFILASPIQRSGLSTRLALTVVSRFGNSQNTLIASILILSALMSFVISSYAVTAMLF
PVVIEVVQAAGAKSGGRFGLAAFLALGWGCGIGGIATLLGGARAPLALGVLRSTTKGEYDITFVEWFLWSVPLVVLMLIV
AYLVLLQIGKGIVVSLSSARKFLEVRSQSLGTISSREIGTLALVTGIVLLWVFKGKAWGLDTIAFFGVMCSFVCGLATWQ
EVEEDVNWGIFLMYGSAIALSAVLRDTGAAQALAENLLGSWINSGFVCFVAMVLIITFLTEGMSNAAAVAVLMPVGLALA
AKYGIDPRAMTLGITLPSGLAFLLPVSTPVMAIIMGSGYVSPAEAFKRGLLLKLVGTLIFLAMAKFYWPLFGWGV
>Mature_475_residues
MENIKYLRTWLRISRQPQYRWLWFVAAALIYLGILLFPMAGVEKEAKGALAVFGVTAFLWATNTLPVAVTGLMVLFLIPL
SGSMSATDTYAYFGNKAVFFVLGAFILASPIQRSGLSTRLALTVVSRFGNSQNTLIASILILSALMSFVISSYAVTAMLF
PVVIEVVQAAGAKSGGRFGLAAFLALGWGCGIGGIATLLGGARAPLALGVLRSTTKGEYDITFVEWFLWSVPLVVLMLIV
AYLVLLQIGKGIVVSLSSARKFLEVRSQSLGTISSREIGTLALVTGIVLLWVFKGKAWGLDTIAFFGVMCSFVCGLATWQ
EVEEDVNWGIFLMYGSAIALSAVLRDTGAAQALAENLLGSWINSGFVCFVAMVLIITFLTEGMSNAAAVAVLMPVGLALA
AKYGIDPRAMTLGITLPSGLAFLLPVSTPVMAIIMGSGYVSPAEAFKRGLLLKLVGTLIFLAMAKFYWPLFGWGV

Specific function: Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=499, Percent_Identity=24.0480961923848, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI4506979, Length=534, Percent_Identity=23.9700374531835, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI301069349, Length=297, Percent_Identity=26.9360269360269, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI31377715, Length=332, Percent_Identity=24.3975903614458, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI58761541, Length=332, Percent_Identity=24.3975903614458, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI301069353, Length=332, Percent_Identity=24.3975903614458, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI19923838, Length=339, Percent_Identity=22.4188790560472, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI225637549, Length=583, Percent_Identity=22.8130360205832, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI225637552, Length=485, Percent_Identity=22.8865979381443, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI301069346, Length=153, Percent_Identity=29.4117647058824, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71988385, Length=461, Percent_Identity=25.1626898047722, Blast_Score=115, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI32565804, Length=444, Percent_Identity=24.7747747747748, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71989118, Length=512, Percent_Identity=22.4609375, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI32564681, Length=475, Percent_Identity=20.6315789473684, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281362116, Length=461, Percent_Identity=25.8134490238612, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281362114, Length=462, Percent_Identity=26.1904761904762, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281362112, Length=462, Percent_Identity=26.1904761904762, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281366409, Length=463, Percent_Identity=24.8380129589633, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17737623, Length=463, Percent_Identity=24.8380129589633, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24666468, Length=463, Percent_Identity=24.8380129589633, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI45551633, Length=463, Percent_Identity=24.8380129589633, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI78706796, Length=458, Percent_Identity=25.1091703056769, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI78706798, Length=458, Percent_Identity=25.1091703056769, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 50706; Mature: 50706

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENIKYLRTWLRISRQPQYRWLWFVAAALIYLGILLFPMAGVEKEAKGALAVFGVTAFLW
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHH
ATNTLPVAVTGLMVLFLIPLSGSMSATDTYAYFGNKAVFFVLGAFILASPIQRSGLSTRL
HCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHCHHHHCCCHHHH
ALTVVSRFGNSQNTLIASILILSALMSFVISSYAVTAMLFPVVIEVVQAAGAKSGGRFGL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
AAFLALGWGCGIGGIATLLGGARAPLALGVLRSTTKGEYDITFVEWFLWSVPLVVLMLIV
HHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHH
AYLVLLQIGKGIVVSLSSARKFLEVRSQSLGTISSREIGTLALVTGIVLLWVFKGKAWGL
HHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCH
DTIAFFGVMCSFVCGLATWQEVEEDVNWGIFLMYGSAIALSAVLRDTGAAQALAENLLGS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHH
WINSGFVCFVAMVLIITFLTEGMSNAAAVAVLMPVGLALAAKYGIDPRAMTLGITLPSGL
HHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCH
AFLLPVSTPVMAIIMGSGYVSPAEAFKRGLLLKLVGTLIFLAMAKFYWPLFGWGV
HHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MENIKYLRTWLRISRQPQYRWLWFVAAALIYLGILLFPMAGVEKEAKGALAVFGVTAFLW
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHH
ATNTLPVAVTGLMVLFLIPLSGSMSATDTYAYFGNKAVFFVLGAFILASPIQRSGLSTRL
HCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHCHHHHCCCHHHH
ALTVVSRFGNSQNTLIASILILSALMSFVISSYAVTAMLFPVVIEVVQAAGAKSGGRFGL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
AAFLALGWGCGIGGIATLLGGARAPLALGVLRSTTKGEYDITFVEWFLWSVPLVVLMLIV
HHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHH
AYLVLLQIGKGIVVSLSSARKFLEVRSQSLGTISSREIGTLALVTGIVLLWVFKGKAWGL
HHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCH
DTIAFFGVMCSFVCGLATWQEVEEDVNWGIFLMYGSAIALSAVLRDTGAAQALAENLLGS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHH
WINSGFVCFVAMVLIITFLTEGMSNAAAVAVLMPVGLALAAKYGIDPRAMTLGITLPSGL
HHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCH
AFLLPVSTPVMAIIMGSGYVSPAEAFKRGLLLKLVGTLIFLAMAKFYWPLFGWGV
HHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: tartrate [Periplasm]; succinate [Cytoplasm] [C]

Specific reaction: tartrate [Periplasm] + succinate [Cytoplasm] = tartrate [Cytoplasm] + succinate [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA