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The map label for this gene is paxA [H]

Identifier: 113477328

GI number: 113477328

Start: 5999123

End: 6001252

Strand: Reverse

Name: paxA [H]

Synonym: Tery_3878

Alternate gene names: 113477328

Gene position: 6001252-5999123 (Counterclockwise)

Preceding gene: 113477329

Following gene: 113477323

Centisome position: 77.43

GC content: 38.78

Gene sequence:

>2130_bases
ATGACTGAATTTTACAGTATTTACATAGAAACGGGGTCTAGTCCTTTGAGTGGGACACGTAACGATGTAGAGGTAAAACT
GTTCGGTAGTCAAAACACTACTGAATATATGGAACTTACGAGCTTTGATGATATCCCATGGGAAAAAAACCAAAACAGAA
CTTTTCATCTGGGAAAATTGAATATTGGCGATTTAGAAGCAGTAGAGTTTCGTCTAAAATTACAAAACGGTCAGAAGCTT
GATCCTCTATCAGAAAGCGATGTGACGTTGGGTCCTGTATTATTGGAGTTAGAAAAAGCAGGGATATTCGATGGGAAGTT
CGATGGGGTATTAGAAGGGGATGAAACATCGGATTTAGAAAGCTTGGATATTGATGGCTGGGGATTAGAATCTTTTACGA
TCTCTGATGGTCAGAAATACTTTGATACTTCAGAACTATCAGGAGAAGAGTCGTACTTGTTTGATGTTAGTGAAACAAAA
AAATTTGATGTTAAAGAAACCGAAAACTTTCCAGGAACCGTTGTTCCAATAGATTTGGTTGGTGGTAGCAATGATATTAT
TGATGGTACTTGGTTTCATGTCTTGGACAAGGGTGAGCTTGATATCAATAACTTAAGAGATAAATTAGGAAGAATTGATC
AAGAACAAAATACATATTTTGTGACACACGGATTCTCTCGTGGAGCGGGAAATAGTTGGATACCAGAAAATAACATCAAC
ATCTCTAATGGTGAGAGGGAAACAAGCAGGGAAACAAGCTTATCAAAAGCGATTCGCCAATACGATCCAAATGCTAATAT
TCTTTTCGTAGATTGGGCTGAAAAAAATTACAAGTTGGATATAAATCTCGAGGCACTGGCCTTGAATTATGCTGAGGCAC
GGGCAAACCTTTCCAAGATCACTGACGATATAGTAGAATATATCACAAGATATAACGTAAATCCTGAAAAGCTAACATTC
GTAGGTCACAGTCTTGGTGCTCAAATTGCTGGACTAGTTGGGCAAAGGGTAGAAATGGATCGAATTATTGGCCTGGATCC
TGGCGGCGTTGAACCTTTCAGTGATTTTTTACCTGATCAGCCCAATGCTCGGCTTTCTGAGGATGATGCTGAAAATGTTT
ATGTTATCCATTCTGAAACGCTATATGGATATGATTGGCCTGCAGGTGACTTTGACCTATATCTCAATGTTACTAATTAT
CAGGATTTGGGTCAATATGGTATAATGATTTACGAACAACCCGTTCCCCAGGAGCAGTGGCATGATTATGCGATAGATGT
TGCTATAAATTTATTCGAAGGCACTGATTACGCAGGGGAATCAAAACGGAGAAATGAAGATGGTTTAGCGGAACTAACAA
ACCTAGATATAGAGACCTTCTTTGATCCTAACTCATATCCCACAACAAAAAATTCATTCTACGACTTACTGAATGAAAAG
TTTCCACAGAACAGAGCTTTATTTTTCGACGAAAACTTACAACCAGAAGTCGATAAAAGCGGCGATGATATAATGAGAGG
TAGTGAAAATGATGATTCCTTAAATAGTGGTCCAGGCAATGATAAAATTATAGGTAAAGGTGGTAACGATACACTCAATA
GCGGTCCAGGCAATGACAAAATATTCGGACAATCTGGGGATGACTATTTAATAGGTCGCTCTGGTAACGATATTTTATTG
GGGGGAAAGGGTGACGATACTCTCGAAGGTGGTATCGGTCGCGATCGCCTCAATGGTGGACCAGGAAACGACGAGCTTAT
AGGTGGTGGCAGTATAGATTTCTTCATTTTTAACACAAACCGACCATTTAATGAAGAAGACTTGGGTAAGGATATCATAA
CTGACTTTAAGGTTGATCAAGACTTTATCCTATTGGATAAATCTACTTTTGATGCCATTGAAAGTGACTCAAGCAGCAGA
AAAAATCCAGGGTTTAGTCGTGTTGAAGAGTTTGAAGTAGTAGAAACAGATGAAAGTGCAGCTAGTTCAGAAGCTATCAT
TGTTCACAGCACAGAAACTGGTAATTTGTTCTACAATCAAAATGGTAGTGCTTCAGGGTTCGGAACAGGTGGTGATTTTG
CCACTGTAGCTCCTGAATTAAGTTCAGAAAACTTTATACTTAGAGTTTAA

Upstream 100 bases:

>100_bases
TACTTGAAGTGTATACTTCAATAATCTCCTGATTATAATCTGGCGCCAGGAAAAGGATATCTATATTTGCTAGTAAAAAA
GTAGTTTTAAGGATAAACTC

Downstream 100 bases:

>100_bases
AGCAGTAGAATTAGAATTCCATTATTAACAGGACTTACGAAATAGGAAATCGTCCAAAATTTAGAAGGAGACTTGCTTAA
TTTTTGATGATATAATATCT

Product: lipase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 709; Mature: 708

Protein sequence:

>709_residues
MTEFYSIYIETGSSPLSGTRNDVEVKLFGSQNTTEYMELTSFDDIPWEKNQNRTFHLGKLNIGDLEAVEFRLKLQNGQKL
DPLSESDVTLGPVLLELEKAGIFDGKFDGVLEGDETSDLESLDIDGWGLESFTISDGQKYFDTSELSGEESYLFDVSETK
KFDVKETENFPGTVVPIDLVGGSNDIIDGTWFHVLDKGELDINNLRDKLGRIDQEQNTYFVTHGFSRGAGNSWIPENNIN
ISNGERETSRETSLSKAIRQYDPNANILFVDWAEKNYKLDINLEALALNYAEARANLSKITDDIVEYITRYNVNPEKLTF
VGHSLGAQIAGLVGQRVEMDRIIGLDPGGVEPFSDFLPDQPNARLSEDDAENVYVIHSETLYGYDWPAGDFDLYLNVTNY
QDLGQYGIMIYEQPVPQEQWHDYAIDVAINLFEGTDYAGESKRRNEDGLAELTNLDIETFFDPNSYPTTKNSFYDLLNEK
FPQNRALFFDENLQPEVDKSGDDIMRGSENDDSLNSGPGNDKIIGKGGNDTLNSGPGNDKIFGQSGDDYLIGRSGNDILL
GGKGDDTLEGGIGRDRLNGGPGNDELIGGGSIDFFIFNTNRPFNEEDLGKDIITDFKVDQDFILLDKSTFDAIESDSSSR
KNPGFSRVEEFEVVETDESAASSEAIIVHSTETGNLFYNQNGSASGFGTGGDFATVAPELSSENFILRV

Sequences:

>Translated_709_residues
MTEFYSIYIETGSSPLSGTRNDVEVKLFGSQNTTEYMELTSFDDIPWEKNQNRTFHLGKLNIGDLEAVEFRLKLQNGQKL
DPLSESDVTLGPVLLELEKAGIFDGKFDGVLEGDETSDLESLDIDGWGLESFTISDGQKYFDTSELSGEESYLFDVSETK
KFDVKETENFPGTVVPIDLVGGSNDIIDGTWFHVLDKGELDINNLRDKLGRIDQEQNTYFVTHGFSRGAGNSWIPENNIN
ISNGERETSRETSLSKAIRQYDPNANILFVDWAEKNYKLDINLEALALNYAEARANLSKITDDIVEYITRYNVNPEKLTF
VGHSLGAQIAGLVGQRVEMDRIIGLDPGGVEPFSDFLPDQPNARLSEDDAENVYVIHSETLYGYDWPAGDFDLYLNVTNY
QDLGQYGIMIYEQPVPQEQWHDYAIDVAINLFEGTDYAGESKRRNEDGLAELTNLDIETFFDPNSYPTTKNSFYDLLNEK
FPQNRALFFDENLQPEVDKSGDDIMRGSENDDSLNSGPGNDKIIGKGGNDTLNSGPGNDKIFGQSGDDYLIGRSGNDILL
GGKGDDTLEGGIGRDRLNGGPGNDELIGGGSIDFFIFNTNRPFNEEDLGKDIITDFKVDQDFILLDKSTFDAIESDSSSR
KNPGFSRVEEFEVVETDESAASSEAIIVHSTETGNLFYNQNGSASGFGTGGDFATVAPELSSENFILRV
>Mature_708_residues
TEFYSIYIETGSSPLSGTRNDVEVKLFGSQNTTEYMELTSFDDIPWEKNQNRTFHLGKLNIGDLEAVEFRLKLQNGQKLD
PLSESDVTLGPVLLELEKAGIFDGKFDGVLEGDETSDLESLDIDGWGLESFTISDGQKYFDTSELSGEESYLFDVSETKK
FDVKETENFPGTVVPIDLVGGSNDIIDGTWFHVLDKGELDINNLRDKLGRIDQEQNTYFVTHGFSRGAGNSWIPENNINI
SNGERETSRETSLSKAIRQYDPNANILFVDWAEKNYKLDINLEALALNYAEARANLSKITDDIVEYITRYNVNPEKLTFV
GHSLGAQIAGLVGQRVEMDRIIGLDPGGVEPFSDFLPDQPNARLSEDDAENVYVIHSETLYGYDWPAGDFDLYLNVTNYQ
DLGQYGIMIYEQPVPQEQWHDYAIDVAINLFEGTDYAGESKRRNEDGLAELTNLDIETFFDPNSYPTTKNSFYDLLNEKF
PQNRALFFDENLQPEVDKSGDDIMRGSENDDSLNSGPGNDKIIGKGGNDTLNSGPGNDKIFGQSGDDYLIGRSGNDILLG
GKGDDTLEGGIGRDRLNGGPGNDELIGGGSIDFFIFNTNRPFNEEDLGKDIITDFKVDQDFILLDKSTFDAIESDSSSRK
NPGFSRVEEFEVVETDESAASSEAIIVHSTETGNLFYNQNGSASGFGTGGDFATVAPELSSENFILRV

Specific function: PaxA is associated with abortion cases in swine and septicemia in young piglets. Shows cohemolytic activity with the sphingomyelinase of S.aureus but is devoid of direct hemolytic activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 6 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR013550
- InterPro:   IPR018504
- InterPro:   IPR003995
- InterPro:   IPR011049 [H]

Pfam domain/function: PF00353 HemolysinCabind; PF02382 RTX; PF08339 RTX_C [H]

EC number: NA

Molecular weight: Translated: 78682; Mature: 78550

Theoretical pI: Translated: 3.93; Mature: 3.93

Prosite motif: PS00120 LIPASE_SER ; PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFYSIYIETGSSPLSGTRNDVEVKLFGSQNTTEYMELTSFDDIPWEKNQNRTFHLGKL
CCCEEEEEEECCCCCCCCCCCCEEEEEECCCCCCHHEEECCCCCCCCCCCCCCEEEEEEC
NIGDLEAVEFRLKLQNGQKLDPLSESDVTLGPVLLELEKAGIFDGKFDGVLEGDETSDLE
CCCCCEEEEEEEEECCCCCCCCCCCCCCEECCEEEEEECCCCCCCCCCCEECCCCCCCCC
SLDIDGWGLESFTISDGQKYFDTSELSGEESYLFDVSETKKFDVKETENFPGTVVPIDLV
EECCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCEECCCCCCCCCCEEEEEEEE
GGSNDIIDGTWFHVLDKGELDINNLRDKLGRIDQEQNTYFVTHGFSRGAGNSWIPENNIN
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
ISNGERETSRETSLSKAIRQYDPNANILFVDWAEKNYKLDINLEALALNYAEARANLSKI
CCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEEEEEEEHHHHHHHHHHH
TDDIVEYITRYNVNPEKLTFVGHSLGAQIAGLVGQRVEMDRIIGLDPGGVEPFSDFLPDQ
HHHHHHHHHHCCCCHHEEEEEEHHHHHHHHHHHCCCCCHHHEEECCCCCCCHHHHHCCCC
PNARLSEDDAENVYVIHSETLYGYDWPAGDFDLYLNVTNYQDLGQYGIMIYEQPVPQEQW
CCCCCCCCCCCCEEEEECCEEEECCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCHHHH
HDYAIDVAINLFEGTDYAGESKRRNEDGLAELTNLDIETFFDPNSYPTTKNSFYDLLNEK
CCEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHH
FPQNRALFFDENLQPEVDKSGDDIMRGSENDDSLNSGPGNDKIIGKGGNDTLNSGPGNDK
CCCCCEEEECCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCE
IFGQSGDDYLIGRSGNDILLGGKGDDTLEGGIGRDRLNGGPGNDELIGGGSIDFFIFNTN
EECCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCEEEEEEEECC
RPFNEEDLGKDIITDFKVDQDFILLDKSTFDAIESDSSSRKNPGFSRVEEFEVVETDESA
CCCCHHHCCHHHHHHCCCCCCEEEEECCHHHHHHCCCCCCCCCCCCHHHHEEEEECCCCC
ASSEAIIVHSTETGNLFYNQNGSASGFGTGGDFATVAPELSSENFILRV
CCCCEEEEEECCCCCEEECCCCCCCCCCCCCCCEEECCCCCCCCEEEEC
>Mature Secondary Structure 
TEFYSIYIETGSSPLSGTRNDVEVKLFGSQNTTEYMELTSFDDIPWEKNQNRTFHLGKL
CCEEEEEEECCCCCCCCCCCCEEEEEECCCCCCHHEEECCCCCCCCCCCCCCEEEEEEC
NIGDLEAVEFRLKLQNGQKLDPLSESDVTLGPVLLELEKAGIFDGKFDGVLEGDETSDLE
CCCCCEEEEEEEEECCCCCCCCCCCCCCEECCEEEEEECCCCCCCCCCCEECCCCCCCCC
SLDIDGWGLESFTISDGQKYFDTSELSGEESYLFDVSETKKFDVKETENFPGTVVPIDLV
EECCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCEECCCCCCCCCCEEEEEEEE
GGSNDIIDGTWFHVLDKGELDINNLRDKLGRIDQEQNTYFVTHGFSRGAGNSWIPENNIN
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
ISNGERETSRETSLSKAIRQYDPNANILFVDWAEKNYKLDINLEALALNYAEARANLSKI
CCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEEEEEEEHHHHHHHHHHH
TDDIVEYITRYNVNPEKLTFVGHSLGAQIAGLVGQRVEMDRIIGLDPGGVEPFSDFLPDQ
HHHHHHHHHHCCCCHHEEEEEEHHHHHHHHHHHCCCCCHHHEEECCCCCCCHHHHHCCCC
PNARLSEDDAENVYVIHSETLYGYDWPAGDFDLYLNVTNYQDLGQYGIMIYEQPVPQEQW
CCCCCCCCCCCCEEEEECCEEEECCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCHHHH
HDYAIDVAINLFEGTDYAGESKRRNEDGLAELTNLDIETFFDPNSYPTTKNSFYDLLNEK
CCEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHH
FPQNRALFFDENLQPEVDKSGDDIMRGSENDDSLNSGPGNDKIIGKGGNDTLNSGPGNDK
CCCCCEEEECCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCE
IFGQSGDDYLIGRSGNDILLGGKGDDTLEGGIGRDRLNGGPGNDELIGGGSIDFFIFNTN
EECCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCEEEEEEEECC
RPFNEEDLGKDIITDFKVDQDFILLDKSTFDAIESDSSSRKNPGFSRVEEFEVVETDESA
CCCCHHHCCHHHHHHCCCCCCEEEEECCHHHHHHCCCCCCCCCCCCHHHHEEEEECCCCC
ASSEAIIVHSTETGNLFYNQNGSASGFGTGGDFATVAPELSSENFILRV
CCCCEEEEEECCCCCEEECCCCCCCCCCCCCCCEEECCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10603361 [H]