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The map label for this gene is sdhB [H]

Identifier: 113477194

GI number: 113477194

Start: 5714303

End: 5715343

Strand: Reverse

Name: sdhB [H]

Synonym: Tery_3726

Alternate gene names: 113477194

Gene position: 5715343-5714303 (Counterclockwise)

Preceding gene: 113477199

Following gene: 113477193

Centisome position: 73.75

GC content: 35.93

Gene sequence:

>1041_bases
ATGAAAGTTAATTTTAATATTGTTAGGCAAAATCAAAATACTCAGCCAAAAATTCAAAGTTACACCCTAGAAATTGAACC
AGGCAATACAATTTTAGAATGCCTAAACCGGATTAAGTGGGAGCAAGATGGAAGTTTAGCTTTTAGGAAAAACTGCCGAA
ATACTATTTGTGGTAGTTGTGCAATGCGAATCAACGGTCGTTCAGCTTTAGCTTGCAAAGAAAATATTAGAAATGAATTA
GCTAGACTCGAAAAAATAGCAACTAACAATCATCATGATTATGTCACCAATACTACTGTAAAATCTATTCCAGAAATCAC
TATTTCTCCTATGGGAAATATGCCAGTAATTAAAGATTTGATTGTAGATATGAACAGCTTTTGGCAAAATCTAGAAGCGG
TTCAACCTTATGTAAGTACAGAAGCACGAAAGATTCCAGAACGGGAATTTTTACAGACTCCTAGTGAACGGGATAAACTC
AATCAAACAGGTAATTGTATTCTCTGTGGGGCTTGTTATTCTGAATGTAATGCTCGTGAAGTAAATCCAGATTTTGTAGG
GCCACACGCCTTAGGGAAAGCTTATAGGATGATAGCTGATTCACGGGACAACCAAACAACAGAAAGATTAGAAAAATATA
ATCTTGATACTGCTGGAGTTTGGGGCTGTACTCGTTGTTATTATTGTAATTCTGTCTGCCCCATGGAAGTTTCACCTATG
GATCAAATAGGTAAGATTAAGCAGGAGGTTCTGGCTCGTAAAGATCAACAAGCTAGTCGTTCTATTCGCCACCGAAAAGT
TTTAATTGATTTGGTTAAGAATGGAGGTTGGATTGATGAAAGAAAATTTGGTATTCAAGTAGTGGGTAATTATTTTCGAG
ATCTTAAAGGTTTATATAGTTTGGGCCCTTTAGGATTAAGGATGTTGGCTAAAGGTAAGTTTCCTTTGATTTTTGAACCT
TCTCAAGGAACTGAAACTGTGCGATCGCTGATTGAATCAGTTAAAAGCTTAGATAATAAATTTACTGGGAGCAAGCAATA
A

Upstream 100 bases:

>100_bases
GTTTTTGCATAAGTTATGAAAAAACTTTAACAGAATGCAGAATAAAGATAATTAAACTAAAACTTAGATAGTATAGAAAA
CTTCAGTAAAATTATTACTT

Downstream 100 bases:

>100_bases
TTTTTATATTTTTTGGTTTTTGGTAGCACTAAAAAAGTAGTTATTTTGTTCATCTACCTTCTGAAAACTGAAGGATAGAA
ATCATCCATTTAATAATCCT

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKVNFNIVRQNQNTQPKIQSYTLEIEPGNTILECLNRIKWEQDGSLAFRKNCRNTICGSCAMRINGRSALACKENIRNEL
ARLEKIATNNHHDYVTNTTVKSIPEITISPMGNMPVIKDLIVDMNSFWQNLEAVQPYVSTEARKIPEREFLQTPSERDKL
NQTGNCILCGACYSECNAREVNPDFVGPHALGKAYRMIADSRDNQTTERLEKYNLDTAGVWGCTRCYYCNSVCPMEVSPM
DQIGKIKQEVLARKDQQASRSIRHRKVLIDLVKNGGWIDERKFGIQVVGNYFRDLKGLYSLGPLGLRMLAKGKFPLIFEP
SQGTETVRSLIESVKSLDNKFTGSKQ

Sequences:

>Translated_346_residues
MKVNFNIVRQNQNTQPKIQSYTLEIEPGNTILECLNRIKWEQDGSLAFRKNCRNTICGSCAMRINGRSALACKENIRNEL
ARLEKIATNNHHDYVTNTTVKSIPEITISPMGNMPVIKDLIVDMNSFWQNLEAVQPYVSTEARKIPEREFLQTPSERDKL
NQTGNCILCGACYSECNAREVNPDFVGPHALGKAYRMIADSRDNQTTERLEKYNLDTAGVWGCTRCYYCNSVCPMEVSPM
DQIGKIKQEVLARKDQQASRSIRHRKVLIDLVKNGGWIDERKFGIQVVGNYFRDLKGLYSLGPLGLRMLAKGKFPLIFEP
SQGTETVRSLIESVKSLDNKFTGSKQ
>Mature_346_residues
MKVNFNIVRQNQNTQPKIQSYTLEIEPGNTILECLNRIKWEQDGSLAFRKNCRNTICGSCAMRINGRSALACKENIRNEL
ARLEKIATNNHHDYVTNTTVKSIPEITISPMGNMPVIKDLIVDMNSFWQNLEAVQPYVSTEARKIPEREFLQTPSERDKL
NQTGNCILCGACYSECNAREVNPDFVGPHALGKAYRMIADSRDNQTTERLEKYNLDTAGVWGCTRCYYCNSVCPMEVSPM
DQIGKIKQEVLARKDQQASRSIRHRKVLIDLVKNGGWIDERKFGIQVVGNYFRDLKGLYSLGPLGLRMLAKGKFPLIFEP
SQGTETVRSLIESVKSLDNKFTGSKQ

Specific function: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth [H]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=261, Percent_Identity=33.3333333333333, Blast_Score=144, Evalue=2e-34,
Organism=Escherichia coli, GI1786943, Length=260, Percent_Identity=36.5384615384615, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1790596, Length=249, Percent_Identity=34.136546184739, Blast_Score=150, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI17533915, Length=253, Percent_Identity=33.9920948616601, Blast_Score=145, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6322987, Length=252, Percent_Identity=32.5396825396825, Blast_Score=136, Evalue=5e-33,
Organism=Drosophila melanogaster, GI17137106, Length=252, Percent_Identity=34.5238095238095, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24643156, Length=257, Percent_Identity=30.7392996108949, Blast_Score=133, Evalue=1e-31,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 39254; Mature: 39254

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVNFNIVRQNQNTQPKIQSYTLEIEPGNTILECLNRIKWEQDGSLAFRKNCRNTICGSC
CCEEEEEEECCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCH
AMRINGRSALACKENIRNELARLEKIATNNHHDYVTNTTVKSIPEITISPMGNMPVIKDL
HEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCEEECCCCCCHHHHHH
IVDMNSFWQNLEAVQPYVSTEARKIPEREFLQTPSERDKLNQTGNCILCGACYSECNARE
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHCCCCCEEEEECHHHCCCCCC
VNPDFVGPHALGKAYRMIADSRDNQTTERLEKYNLDTAGVWGCTRCYYCNSVCPMEVSPM
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHEECCCCCCCCCCH
DQIGKIKQEVLARKDQQASRSIRHRKVLIDLVKNGGWIDERKFGIQVVGNYFRDLKGLYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
LGPLGLRMLAKGKFPLIFEPSQGTETVRSLIESVKSLDNKFTGSKQ
CCHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKVNFNIVRQNQNTQPKIQSYTLEIEPGNTILECLNRIKWEQDGSLAFRKNCRNTICGSC
CCEEEEEEECCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCH
AMRINGRSALACKENIRNELARLEKIATNNHHDYVTNTTVKSIPEITISPMGNMPVIKDL
HEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCEEECCCCCCHHHHHH
IVDMNSFWQNLEAVQPYVSTEARKIPEREFLQTPSERDKLNQTGNCILCGACYSECNARE
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHCCCCCEEEEECHHHCCCCCC
VNPDFVGPHALGKAYRMIADSRDNQTTERLEKYNLDTAGVWGCTRCYYCNSVCPMEVSPM
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHEECCCCCCCCCCH
DQIGKIKQEVLARKDQQASRSIRHRKVLIDLVKNGGWIDERKFGIQVVGNYFRDLKGLYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
LGPLGLRMLAKGKFPLIFEPSQGTETVRSLIESVKSLDNKFTGSKQ
CCHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6388571; 8905232; 9278503; 6376123; 9298646 [H]