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The map label for this gene is lspA [H]

Identifier: 113477031

GI number: 113477031

Start: 5443751

End: 5444248

Strand: Reverse

Name: lspA [H]

Synonym: Tery_3531

Alternate gene names: 113477031

Gene position: 5444248-5443751 (Counterclockwise)

Preceding gene: 113477032

Following gene: 113477028

Centisome position: 70.25

GC content: 31.12

Gene sequence:

>498_bases
TTGTTAAAGTTGAAATTACGTTTTAAAAAAAATTCCTTATTCTGGATAGTTGCTATTATCAGCATTATTTTAGACCATTT
GACTAAATTTTGGGTGGTACAAAATTTTCAATTAGAAGAAAGTATGGTTTTATGGCCTGGTGTATTTAACTTTACTTATG
TAACTAATACTGGAGCAGCTTTTAGTCTGTTTAGTAATGGTGGAGTTTCTTGGTTGCGCTGGTTATCTTTAATAGTTAGT
CTAGGTCTCATGGGTTTTGCTTGGTTTGGACCGAAGTTTGATAGATGGGAACAACTAGGTTATGGTTTAATTTTAGGAGG
AGCATTGGGTAATGGTATTGATAGGTTTGTTTCTGGTTATGTCGTTGACTTTTTGCATTTTAGCCTTATAAATTTTCCTA
TTTTTAATGTGGCAGATGTTTCTATTAATATTGGTATTATTTGCTTACTAGTTGCTACATTTTTTGCTGAAATACCTAAG
TTAGGTAATAAAAAATAA

Upstream 100 bases:

>100_bases
TAGTAAGTGGGTATATAAAATAAATTACACACTTGAAAAACTAAAATTTAATCTTTGTCTAAATATCGCGCTTTGCAAAT
AATTTTGTGTAGTTGCTTAA

Downstream 100 bases:

>100_bases
GAAGTATGGAAAAAAATATTGATTCAATTAATTTTACGAGATTAATATCAAATATGCTATGAATTGAAGCTGAAGTTTTT
ATTTCTCACTTTTTTCTTTT

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MLKLKLRFKKNSLFWIVAIISIILDHLTKFWVVQNFQLEESMVLWPGVFNFTYVTNTGAAFSLFSNGGVSWLRWLSLIVS
LGLMGFAWFGPKFDRWEQLGYGLILGGALGNGIDRFVSGYVVDFLHFSLINFPIFNVADVSINIGIICLLVATFFAEIPK
LGNKK

Sequences:

>Translated_165_residues
MLKLKLRFKKNSLFWIVAIISIILDHLTKFWVVQNFQLEESMVLWPGVFNFTYVTNTGAAFSLFSNGGVSWLRWLSLIVS
LGLMGFAWFGPKFDRWEQLGYGLILGGALGNGIDRFVSGYVVDFLHFSLINFPIFNVADVSINIGIICLLVATFFAEIPK
LGNKK
>Mature_165_residues
MLKLKLRFKKNSLFWIVAIISIILDHLTKFWVVQNFQLEESMVLWPGVFNFTYVTNTGAAFSLFSNGGVSWLRWLSLIVS
LGLMGFAWFGPKFDRWEQLGYGLILGGALGNGIDRFVSGYVVDFLHFSLINFPIFNVADVSINIGIICLLVATFFAEIPK
LGNKK

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=152, Percent_Identity=32.8947368421053, Blast_Score=77, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 18648; Mature: 18648

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKLKLRFKKNSLFWIVAIISIILDHLTKFWVVQNFQLEESMVLWPGVFNFTYVTNTGAA
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEEECCCCE
FSLFSNGGVSWLRWLSLIVSLGLMGFAWFGPKFDRWEQLGYGLILGGALGNGIDRFVSGY
EEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEECCHHCCHHHHHHHHH
VVDFLHFSLINFPIFNVADVSINIGIICLLVATFFAEIPKLGNKK
HHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLKLKLRFKKNSLFWIVAIISIILDHLTKFWVVQNFQLEESMVLWPGVFNFTYVTNTGAA
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEEECCCCE
FSLFSNGGVSWLRWLSLIVSLGLMGFAWFGPKFDRWEQLGYGLILGGALGNGIDRFVSGY
EEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEECCHHCCHHHHHHHHH
VVDFLHFSLINFPIFNVADVSINIGIICLLVATFFAEIPKLGNKK
HHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA