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The map label for this gene is clpB1 [H]

Identifier: 113476992

GI number: 113476992

Start: 5379592

End: 5382309

Strand: Reverse

Name: clpB1 [H]

Synonym: Tery_3490

Alternate gene names: 113476992

Gene position: 5382309-5379592 (Counterclockwise)

Preceding gene: 113476993

Following gene: 113476988

Centisome position: 69.45

GC content: 41.32

Gene sequence:

>2718_bases
ATGCAGCCAACTGACCCAAGCAAATTTACAGAACAAGCCTGGGATGCTATAGTAAAATCCCAAGACGTTGCCAAACGCTA
CCAAAACCAACAACTGGAAGTAGAACACCTAATTATTGCCCTCCTAGAACAACAAGGCACAGCGAATAAAATCTTAAGCC
GTTCTGGTATAGAACCAGAAAAGCTCCTACAACAAGTAGATGCTTTTGTGAGACGTCAACCTAAAGTTGGCAGTATAGAA
CATCTATATTTAGGTCAAGGTCTGGAAACTTTTTTAGACCTGGCTGATCAAGCTAAAGAAAAGTGGGAAGATAAATTTAT
TGCTGTGGAACACTTTCTACTCGCTTTTCACGAAGATAAACGTCTGGGTAATAAACTTATTGGTGGTGGAACTCCCCAAC
TACCAACTCGCCCTGGTTTTGCTCCCCCCCAAACTACTCTACAAATTGAATTTAAAGAACTAGAGGCAACTATTAAAGCA
TTTCGAGGTAGTAGCAAAGTCGAAGACCAAAACCCAGAAGCTACTTATGATGCTTTAGCTAAATATGGGCGTGACCTGAC
AGAGTTAGCGAAAGTAGGTAAACTTGACCCGGTTATTGGCAGAGATGAGGAAGTTCGGCGGGTGGTTAGTTGTCTATCTC
GTCGGACAAAAAATAATCCTGTACTTATTGGAGAACCGGGGGTGGGAAAAACAGCGATCGCGGAGGGTTTAGCTCAACGT
ATTGTTAATGGTGATGTGCCAGAGTCTCTTAAAGAACGTCAACTTATTAGTCTTGATATGGGTAGTCTCATTGCGGGGGC
TAAGTTTAGAGGAGAATTTGAAGAACGTCTTAGATCGGTTTTACGAGAAGTTACCCATTCTGATGGTCAAATAGTTCTGT
TTATTGATGAGTTACATACAGTTGTTGGAGCAGGTTCTGGTGGGGGTAACAGTTCTGGTGTAGATGCCGGAAATTTGTTG
AAACCAATGCTGGCTCGTGGTGAACTGCGTTGTATCGGTGCAACAACTATTGATGAATATCGCAAACATATAGAAAAAGA
TGCTGCCCTGGAACGTCGGTTTCAAAAAGTAGAGGTTGGTCAGCCTAGTGTTGAGGATACTATTTCTATTTTGCGGGGGT
TGAAAGACCGCTACGAAACTCACCACGGTGTGAAAATTACTGATGCGGCTTTGGTTGCTGCTGCTACTTTGTCTAACCGA
TATATTTCTGACCGCTTTTTGCCAGATAAGGCGATCGACTTGGTAGATGAAGCTGCTGCTCAATTAAAAATGGAAATTAC
TTCTAAACCAGTTGAGTTAGAAGCTATTGACAGACGGATAATGCAGTTGGAAATGGAGAAACTTTCTATTGAGGGAGAGT
TGTCAGGTACTAATAAGGAAAAAAATTCTGAAGCTATTCTGTCTACAAAGGTATCTCCTGCTTTAGAGCGCATTACTAAT
GAAATTAATAGTTTAAAGCAAAAGCAGGAGAAATTTTCTTCTCAATGGTCTGGGGAAAAAGAGTTGTTAAATTCTATTAA
TTCTTTGAAGGCAGAAGAAGATAAAATTAAAGTACAAATAGAACAAGCAGAACGAGCTTATGATCTGAATACGGCAGCTC
AGTTAAAATATGGGCAATTAGAAACAGTTCATCGCGATCGCGAAGCCCAAGAGGCAGAGTTATTAAAAGTGCAAGCTCAA
GGTTCTTTTCTCCTCCGAGAACAGGTGACTGATGGGGATATTGCTACAATTGTTGCTAAGTGGACTGGTATTCCGGTAAA
TCGTTTATTGGAGTCGGAACGGCAGAAATTACTACAACTGGAAAAACATCTTCATCAAAGGGTTATTGGGCAGTCAGAAG
CTGTAGCAGCTGTAGCAGCAGCTATTAGAAGGGCGAGAGCAGGAATGAAAGACCCAGGAAGACCCATTGGTTCGTTTATG
TTTTTGGGTCCGACTGGGGTTGGTAAAACTGAGTTGGCGCGGGCATTGGCAGGGTTTCTCTTTGACCGGGATGATGCTTT
GGTACGAGTTGATATGTCGGAATATATGGAGAAACATGCTGTTGCTCGCTTGGTGGGTGCTCCCCCTGGATATGTGGGTT
ATGACCAAGGGGGTCAATTATCGGAGGCAGTCAGGCGACATCCTTATTCTTTGGTATTGTTTGATGAGGTGGAGAAGGCG
CACCCAGATGTGTTTAATATTTTGTTGCAGGTTTTGGATGATGGTCGAATTACTGATTCTCAGGGTCGGGTTATTGATTT
TAGTAATACTGTAATTGTGATGACTAGTAATATTGGTAGTGAGTATATTTTAGATGTGGCGGGAGATGATTCTAAGTATG
AGGAGATGTATAAGCGGGTGATGGGAGCACTGCGAAAACATTTCCGCCCTGAATTTTTAAATAGGGTAGATGAGATTATT
TTATTCCATACTCTAAGGAAGAGTGAATTACGTCAAATTGTGGAAATTCAAGTCAAGAGAATTGAACGGTTATTAGGAGA
ACAAAAGATTAGTTTGCAGTTGACTGATGCGACTTTAGATCACATTACTGAAGTAGGATATGACCCAGTTTATGGAGCCA
GACCTTTAAAGCGGGCAATTCAGCGAGAATTAGAAAATCCTCTGGCAAATCAAATTTTGGAGAATAGGTTTGTTTGTGGG
GATGTTGTGATCATTGATTTTGTAGATAGTGGTTTAGTTTTTAAGAAAAAAGAGGAGGGAAAATTGGTAAAAAGGTGA

Upstream 100 bases:

>100_bases
GGCAAAATGCCCATTATACAAAAATATTACAGTCATCCCCCATTATCTATAAGTGCTATACCAGAAAAAACCTTAAAGGA
AAAAATTTAAAATACTTCAA

Downstream 100 bases:

>100_bases
TTATATAAATTGCGAGCTTCTAGCTCGCCTATGGTTAAATTATAAATTATTAGATATAGAAGTAGCTTAATATAATTTTA
CCATTAAACTTCAAAGAAAA

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 905; Mature: 905

Protein sequence:

>905_residues
MQPTDPSKFTEQAWDAIVKSQDVAKRYQNQQLEVEHLIIALLEQQGTANKILSRSGIEPEKLLQQVDAFVRRQPKVGSIE
HLYLGQGLETFLDLADQAKEKWEDKFIAVEHFLLAFHEDKRLGNKLIGGGTPQLPTRPGFAPPQTTLQIEFKELEATIKA
FRGSSKVEDQNPEATYDALAKYGRDLTELAKVGKLDPVIGRDEEVRRVVSCLSRRTKNNPVLIGEPGVGKTAIAEGLAQR
IVNGDVPESLKERQLISLDMGSLIAGAKFRGEFEERLRSVLREVTHSDGQIVLFIDELHTVVGAGSGGGNSSGVDAGNLL
KPMLARGELRCIGATTIDEYRKHIEKDAALERRFQKVEVGQPSVEDTISILRGLKDRYETHHGVKITDAALVAAATLSNR
YISDRFLPDKAIDLVDEAAAQLKMEITSKPVELEAIDRRIMQLEMEKLSIEGELSGTNKEKNSEAILSTKVSPALERITN
EINSLKQKQEKFSSQWSGEKELLNSINSLKAEEDKIKVQIEQAERAYDLNTAAQLKYGQLETVHRDREAQEAELLKVQAQ
GSFLLREQVTDGDIATIVAKWTGIPVNRLLESERQKLLQLEKHLHQRVIGQSEAVAAVAAAIRRARAGMKDPGRPIGSFM
FLGPTGVGKTELARALAGFLFDRDDALVRVDMSEYMEKHAVARLVGAPPGYVGYDQGGQLSEAVRRHPYSLVLFDEVEKA
HPDVFNILLQVLDDGRITDSQGRVIDFSNTVIVMTSNIGSEYILDVAGDDSKYEEMYKRVMGALRKHFRPEFLNRVDEII
LFHTLRKSELRQIVEIQVKRIERLLGEQKISLQLTDATLDHITEVGYDPVYGARPLKRAIQRELENPLANQILENRFVCG
DVVIIDFVDSGLVFKKKEEGKLVKR

Sequences:

>Translated_905_residues
MQPTDPSKFTEQAWDAIVKSQDVAKRYQNQQLEVEHLIIALLEQQGTANKILSRSGIEPEKLLQQVDAFVRRQPKVGSIE
HLYLGQGLETFLDLADQAKEKWEDKFIAVEHFLLAFHEDKRLGNKLIGGGTPQLPTRPGFAPPQTTLQIEFKELEATIKA
FRGSSKVEDQNPEATYDALAKYGRDLTELAKVGKLDPVIGRDEEVRRVVSCLSRRTKNNPVLIGEPGVGKTAIAEGLAQR
IVNGDVPESLKERQLISLDMGSLIAGAKFRGEFEERLRSVLREVTHSDGQIVLFIDELHTVVGAGSGGGNSSGVDAGNLL
KPMLARGELRCIGATTIDEYRKHIEKDAALERRFQKVEVGQPSVEDTISILRGLKDRYETHHGVKITDAALVAAATLSNR
YISDRFLPDKAIDLVDEAAAQLKMEITSKPVELEAIDRRIMQLEMEKLSIEGELSGTNKEKNSEAILSTKVSPALERITN
EINSLKQKQEKFSSQWSGEKELLNSINSLKAEEDKIKVQIEQAERAYDLNTAAQLKYGQLETVHRDREAQEAELLKVQAQ
GSFLLREQVTDGDIATIVAKWTGIPVNRLLESERQKLLQLEKHLHQRVIGQSEAVAAVAAAIRRARAGMKDPGRPIGSFM
FLGPTGVGKTELARALAGFLFDRDDALVRVDMSEYMEKHAVARLVGAPPGYVGYDQGGQLSEAVRRHPYSLVLFDEVEKA
HPDVFNILLQVLDDGRITDSQGRVIDFSNTVIVMTSNIGSEYILDVAGDDSKYEEMYKRVMGALRKHFRPEFLNRVDEII
LFHTLRKSELRQIVEIQVKRIERLLGEQKISLQLTDATLDHITEVGYDPVYGARPLKRAIQRELENPLANQILENRFVCG
DVVIIDFVDSGLVFKKKEEGKLVKR
>Mature_905_residues
MQPTDPSKFTEQAWDAIVKSQDVAKRYQNQQLEVEHLIIALLEQQGTANKILSRSGIEPEKLLQQVDAFVRRQPKVGSIE
HLYLGQGLETFLDLADQAKEKWEDKFIAVEHFLLAFHEDKRLGNKLIGGGTPQLPTRPGFAPPQTTLQIEFKELEATIKA
FRGSSKVEDQNPEATYDALAKYGRDLTELAKVGKLDPVIGRDEEVRRVVSCLSRRTKNNPVLIGEPGVGKTAIAEGLAQR
IVNGDVPESLKERQLISLDMGSLIAGAKFRGEFEERLRSVLREVTHSDGQIVLFIDELHTVVGAGSGGGNSSGVDAGNLL
KPMLARGELRCIGATTIDEYRKHIEKDAALERRFQKVEVGQPSVEDTISILRGLKDRYETHHGVKITDAALVAAATLSNR
YISDRFLPDKAIDLVDEAAAQLKMEITSKPVELEAIDRRIMQLEMEKLSIEGELSGTNKEKNSEAILSTKVSPALERITN
EINSLKQKQEKFSSQWSGEKELLNSINSLKAEEDKIKVQIEQAERAYDLNTAAQLKYGQLETVHRDREAQEAELLKVQAQ
GSFLLREQVTDGDIATIVAKWTGIPVNRLLESERQKLLQLEKHLHQRVIGQSEAVAAVAAAIRRARAGMKDPGRPIGSFM
FLGPTGVGKTELARALAGFLFDRDDALVRVDMSEYMEKHAVARLVGAPPGYVGYDQGGQLSEAVRRHPYSLVLFDEVEKA
HPDVFNILLQVLDDGRITDSQGRVIDFSNTVIVMTSNIGSEYILDVAGDDSKYEEMYKRVMGALRKHFRPEFLNRVDEII
LFHTLRKSELRQIVEIQVKRIERLLGEQKISLQLTDATLDHITEVGYDPVYGARPLKRAIQRELENPLANQILENRFVCG
DVVIIDFVDSGLVFKKKEEGKLVKR

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=321, Percent_Identity=36.7601246105919, Blast_Score=204, Evalue=4e-52,
Organism=Escherichia coli, GI1788943, Length=889, Percent_Identity=52.0809898762655, Blast_Score=899, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=251, Percent_Identity=51.394422310757, Blast_Score=275, Evalue=7e-75,
Organism=Saccharomyces cerevisiae, GI6320464, Length=728, Percent_Identity=50.2747252747253, Blast_Score=712, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=898, Percent_Identity=41.5367483296214, Blast_Score=637, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 101171; Mature: 101171

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPTDPSKFTEQAWDAIVKSQDVAKRYQNQQLEVEHLIIALLEQQGTANKILSRSGIEPE
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHH
KLLQQVDAFVRRQPKVGSIEHLYLGQGLETFLDLADQAKEKWEDKFIAVEHFLLAFHEDK
HHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLGNKLIGGGTPQLPTRPGFAPPQTTLQIEFKELEATIKAFRGSSKVEDQNPEATYDALA
HHCCHHCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
KYGRDLTELAKVGKLDPVIGRDEEVRRVVSCLSRRTKNNPVLIGEPGVGKTAIAEGLAQR
HHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHH
IVNGDVPESLKERQLISLDMGSLIAGAKFRGEFEERLRSVLREVTHSDGQIVLFIDELHT
HHCCCCCHHHHHHHHHHCCHHHHHHCHHHCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHH
VVGAGSGGGNSSGVDAGNLLKPMLARGELRCIGATTIDEYRKHIEKDAALERRFQKVEVG
HHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCC
QPSVEDTISILRGLKDRYETHHGVKITDAALVAAATLSNRYISDRFLPDKAIDLVDEAAA
CCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QLKMEITSKPVELEAIDRRIMQLEMEKLSIEGELSGTNKEKNSEAILSTKVSPALERITN
HHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
EINSLKQKQEKFSSQWSGEKELLNSINSLKAEEDKIKVQIEQAERAYDLNTAAQLKYGQL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHEEEEEHHHHHHCCCHHHHCCCCHH
ETVHRDREAQEAELLKVQAQGSFLLREQVTDGDIATIVAKWTGIPVNRLLESERQKLLQL
HHHHHHHHHHHHHHHEEECCCCEEEHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EKHLHQRVIGQSEAVAAVAAAIRRARAGMKDPGRPIGSFMFLGPTGVGKTELARALAGFL
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHH
FDRDDALVRVDMSEYMEKHAVARLVGAPPGYVGYDQGGQLSEAVRRHPYSLVLFDEVEKA
HCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCEEEEEHHHHHH
HPDVFNILLQVLDDGRITDSQGRVIDFSNTVIVMTSNIGSEYILDVAGDDSKYEEMYKRV
CCHHHHHHHHHHCCCCEECCCCCEEEECCEEEEEECCCCCCEEEEECCCCHHHHHHHHHH
MGALRKHFRPEFLNRVDEIILFHTLRKSELRQIVEIQVKRIERLLGEQKISLQLTDATLD
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHH
HITEVGYDPVYGARPLKRAIQRELENPLANQILENRFVCGDVVIIDFVDSGLVFKKKEEG
HHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCEEEEEECCCCCEEEECCCC
KLVKR
CCCCC
>Mature Secondary Structure
MQPTDPSKFTEQAWDAIVKSQDVAKRYQNQQLEVEHLIIALLEQQGTANKILSRSGIEPE
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHH
KLLQQVDAFVRRQPKVGSIEHLYLGQGLETFLDLADQAKEKWEDKFIAVEHFLLAFHEDK
HHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLGNKLIGGGTPQLPTRPGFAPPQTTLQIEFKELEATIKAFRGSSKVEDQNPEATYDALA
HHCCHHCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
KYGRDLTELAKVGKLDPVIGRDEEVRRVVSCLSRRTKNNPVLIGEPGVGKTAIAEGLAQR
HHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHH
IVNGDVPESLKERQLISLDMGSLIAGAKFRGEFEERLRSVLREVTHSDGQIVLFIDELHT
HHCCCCCHHHHHHHHHHCCHHHHHHCHHHCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHH
VVGAGSGGGNSSGVDAGNLLKPMLARGELRCIGATTIDEYRKHIEKDAALERRFQKVEVG
HHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCC
QPSVEDTISILRGLKDRYETHHGVKITDAALVAAATLSNRYISDRFLPDKAIDLVDEAAA
CCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QLKMEITSKPVELEAIDRRIMQLEMEKLSIEGELSGTNKEKNSEAILSTKVSPALERITN
HHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
EINSLKQKQEKFSSQWSGEKELLNSINSLKAEEDKIKVQIEQAERAYDLNTAAQLKYGQL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHEEEEEHHHHHHCCCHHHHCCCCHH
ETVHRDREAQEAELLKVQAQGSFLLREQVTDGDIATIVAKWTGIPVNRLLESERQKLLQL
HHHHHHHHHHHHHHHEEECCCCEEEHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EKHLHQRVIGQSEAVAAVAAAIRRARAGMKDPGRPIGSFMFLGPTGVGKTELARALAGFL
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHH
FDRDDALVRVDMSEYMEKHAVARLVGAPPGYVGYDQGGQLSEAVRRHPYSLVLFDEVEKA
HCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCEEEEEHHHHHH
HPDVFNILLQVLDDGRITDSQGRVIDFSNTVIVMTSNIGSEYILDVAGDDSKYEEMYKRV
CCHHHHHHHHHHCCCCEECCCCCEEEECCEEEEEECCCCCCEEEEECCCCHHHHHHHHHH
MGALRKHFRPEFLNRVDEIILFHTLRKSELRQIVEIQVKRIERLLGEQKISLQLTDATLD
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHH
HITEVGYDPVYGARPLKRAIQRELENPLANQILENRFVCGDVVIIDFVDSGLVFKKKEEG
HHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCEEEEEECCCCCEEEECCCC
KLVKR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]