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The map label for this gene is appC [H]

Identifier: 113476530

GI number: 113476530

Start: 4593896

End: 4594963

Strand: Reverse

Name: appC [H]

Synonym: Tery_2957

Alternate gene names: 113476530

Gene position: 4594963-4593896 (Counterclockwise)

Preceding gene: 113476531

Following gene: 113476529

Centisome position: 59.29

GC content: 36.99

Gene sequence:

>1068_bases
ATGAAATGGTGGAAAAATCTTAAAAAAAATCCTTTAGCAAAATTTGGTGGATTATTGCTATTAATTTTCTATTTGGTAGT
AATTGCTGCTGACTTTATTGCTCCCTATGACGCCTATACATCTCAACCCAACGGTTCCCTATTACCTCCTACTCAAATTT
ACTGGCAAAACCAAGCAGGTGAGTTTATTGGACCTCATGTTTACCCCACGACTCAAGGACCGGTAGATTTAGAAACTGGA
CTCCGGGAGTTAAAGGTAGATTTGAGTAAACCATCCCCTCTAGGTTTATTTGTCCAAGGACCATCCTATAAACTCTTGGG
GATTTTGCCCTGGAATCGACATTTGTTTGGAACGATAGGTCAAGCAAAATTTAATTTATTAGGTACTGACGAACAAGCAA
GAGACCAATTTAGTCGTTTAATTTTTGGTGGTAGGATTAGTTTATTTATTGGTTTAGTAGGAATTACAATCTATTTTCCT
TTGGGAATGATTATTGGTGGAATTTCTGGTTACTTTGGTGGTTGGATAGATAGTATTTTAATGCGTTTTGCTGAAGTATT
AATGACTATTCCGGGTATTTATTTATTAGTGGCACTCGCTGCTATATTACCTCCTGGTTTAACTAGTGCCCAAAGATTTC
TCTTAATTGTGGTGATTACTTCATTTATTAGTTGGGCAGGGTTAGCTAGAGTTATTCGTGGAGAAGTCTTATCTATCAAA
GAACGAGAATTTGTTCAAGCAGTTAGGGCGATGGGGGCAGGTTCTTTTTATATCATTGTTCGCCATGTATTACCCCAAAC
AGCAACTTATGTGATTATTTCAGCAACTTTAGCTATTCCTAGCTTTATTATCTCAGAATCAGTTTTGAGTTTGATTGGTT
TAGGTATTCAACAGCCAGACCCTTCTTGGGGGAATATGTTATCTTTGGCTACAAACGCTTCTATCTTAGTATTACAACCT
TGGTTAGTATGGCCTCCAGCACTATTGATTATTCTGACGGTATTAGCATTTAATTTATTAGGAGATGGGTTGCGAGATGC
TTTAGATCCCAGAAATTTACAACAATAA

Upstream 100 bases:

>100_bases
TGATGGTTTGACGATTAAAACCTAAATACAATTATGGATAGTTGTTTTTTTACTTTTCAAACAGGTTCTAACTATTCTTA
TTCTCTATTAGATAAAATCA

Downstream 100 bases:

>100_bases
TAAATATTAGTTAATAGTTTAAACGGAGAAATAATTATCTTAGTATTATTAATAACTCAATAGGGTTAATTATATTTATC
AGTTATTTTTACATAACAAA

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MKWWKNLKKNPLAKFGGLLLLIFYLVVIAADFIAPYDAYTSQPNGSLLPPTQIYWQNQAGEFIGPHVYPTTQGPVDLETG
LRELKVDLSKPSPLGLFVQGPSYKLLGILPWNRHLFGTIGQAKFNLLGTDEQARDQFSRLIFGGRISLFIGLVGITIYFP
LGMIIGGISGYFGGWIDSILMRFAEVLMTIPGIYLLVALAAILPPGLTSAQRFLLIVVITSFISWAGLARVIRGEVLSIK
EREFVQAVRAMGAGSFYIIVRHVLPQTATYVIISATLAIPSFIISESVLSLIGLGIQQPDPSWGNMLSLATNASILVLQP
WLVWPPALLIILTVLAFNLLGDGLRDALDPRNLQQ

Sequences:

>Translated_355_residues
MKWWKNLKKNPLAKFGGLLLLIFYLVVIAADFIAPYDAYTSQPNGSLLPPTQIYWQNQAGEFIGPHVYPTTQGPVDLETG
LRELKVDLSKPSPLGLFVQGPSYKLLGILPWNRHLFGTIGQAKFNLLGTDEQARDQFSRLIFGGRISLFIGLVGITIYFP
LGMIIGGISGYFGGWIDSILMRFAEVLMTIPGIYLLVALAAILPPGLTSAQRFLLIVVITSFISWAGLARVIRGEVLSIK
EREFVQAVRAMGAGSFYIIVRHVLPQTATYVIISATLAIPSFIISESVLSLIGLGIQQPDPSWGNMLSLATNASILVLQP
WLVWPPALLIILTVLAFNLLGDGLRDALDPRNLQQ
>Mature_355_residues
MKWWKNLKKNPLAKFGGLLLLIFYLVVIAADFIAPYDAYTSQPNGSLLPPTQIYWQNQAGEFIGPHVYPTTQGPVDLETG
LRELKVDLSKPSPLGLFVQGPSYKLLGILPWNRHLFGTIGQAKFNLLGTDEQARDQFSRLIFGGRISLFIGLVGITIYFP
LGMIIGGISGYFGGWIDSILMRFAEVLMTIPGIYLLVALAAILPPGLTSAQRFLLIVVITSFISWAGLARVIRGEVLSIK
EREFVQAVRAMGAGSFYIIVRHVLPQTATYVIISATLAIPSFIISESVLSLIGLGIQQPDPSWGNMLSLATNASILVLQP
WLVWPPALLIILTVLAFNLLGDGLRDALDPRNLQQ

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=225, Percent_Identity=40.4444444444444, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI1787498, Length=228, Percent_Identity=39.0350877192982, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI1787760, Length=224, Percent_Identity=38.3928571428571, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1789964, Length=236, Percent_Identity=38.135593220339, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1789889, Length=225, Percent_Identity=36, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1788505, Length=233, Percent_Identity=29.6137339055794, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1787549, Length=260, Percent_Identity=30, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 38944; Mature: 38944

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWWKNLKKNPLAKFGGLLLLIFYLVVIAADFIAPYDAYTSQPNGSLLPPTQIYWQNQAG
CCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCHHEEECCCCC
EFIGPHVYPTTQGPVDLETGLRELKVDLSKPSPLGLFVQGPSYKLLGILPWNRHLFGTIG
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEECCCCHHHHCCC
QAKFNLLGTDEQARDQFSRLIFGGRISLFIGLVGITIYFPLGMIIGGISGYFGGWIDSIL
CCEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRFAEVLMTIPGIYLLVALAAILPPGLTSAQRFLLIVVITSFISWAGLARVIRGEVLSIK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EREFVQAVRAMGAGSFYIIVRHVLPQTATYVIISATLAIPSFIISESVLSLIGLGIQQPD
HHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PSWGNMLSLATNASILVLQPWLVWPPALLIILTVLAFNLLGDGLRDALDPRNLQQ
CCHHCEEHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKWWKNLKKNPLAKFGGLLLLIFYLVVIAADFIAPYDAYTSQPNGSLLPPTQIYWQNQAG
CCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCHHEEECCCCC
EFIGPHVYPTTQGPVDLETGLRELKVDLSKPSPLGLFVQGPSYKLLGILPWNRHLFGTIG
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEECCCCHHHHCCC
QAKFNLLGTDEQARDQFSRLIFGGRISLFIGLVGITIYFPLGMIIGGISGYFGGWIDSIL
CCEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRFAEVLMTIPGIYLLVALAAILPPGLTSAQRFLLIVVITSFISWAGLARVIRGEVLSIK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EREFVQAVRAMGAGSFYIIVRHVLPQTATYVIISATLAIPSFIISESVLSLIGLGIQQPD
HHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PSWGNMLSLATNASILVLQPWLVWPPALLIILTVLAFNLLGDGLRDALDPRNLQQ
CCHHCEEHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]