Click here to switch to the map view.

The map label for this gene is fusA [C]

Identifier: 113476366

GI number: 113476366

Start: 4296676

End: 4298742

Strand: Reverse

Name: fusA [C]

Synonym: Tery_2771

Alternate gene names: 113476366

Gene position: 4298742-4296676 (Counterclockwise)

Preceding gene: 113476367

Following gene: 113476365

Centisome position: 55.47

GC content: 41.22

Gene sequence:

>2067_bases
ATGTCAGAAAAAGTCGCTTCAAATGTCAGGAATATTGCCATAGTAGGCCCTTATTTAAGTGGAAAAACAACATTACTAGA
AAGCCTATTATCAATTACAAAAGCAATATCCCGTAAAGGCAGTGTTAAAGATGGTAACACCATTGGAGATGGTAGTCCAG
AAGCTCGCGATCGCTCCATGACAGTAGAAATAAATGCCGCTAGTACTAAGTACGACGGCATTAACTTTACCTTTCTAGAC
TGCCCTGGTTCCATAGAATTTGCTCAAGAAACCAATAACGCTCTTATTGGAGCAGGGGCAGCAATAGTCGTGTGTGAACC
AGACCCAGCTCGTGTTCTAACCCTTGCTCCACTATTAAAATTTCTTGATGACTGGGAAATTCCTCATATAGTCTTCATCA
ACAAAATGGATCGGGTCTGTAGGGATGAAACTCATTGTAAATCTAACTTTGGTGAAGTATTAGAAGCACTCAAAACTGTA
TCCAACCGCCCCATTGTTCCCCATCAATACCCCATTGCTAAAAATAACCAACTTATTGGATTTATTGACCTAGTAACTGA
ACAAGCTTATCATTATCATCCAGGGGCGCCATCAGACCCTGTAACAATTCCTGAGTCTTTGAAAGTAGAAGAACAAGCTG
CTAGAGAACAAATGCTGGAAGAGTTAGCTAATTTTGATGATAATTTATTGGAAGAGTTGGTCGAAAATATCGAACCACCT
ACTGAAGAAATAGTTGCTGACATCAAAATGGAGTTAAGTGCAGATTTAATTGTACCTGTATTTGTAGGGGTGGCAGAAAA
AGATTCTGGTGTGCGTTCCCTCCTAGATGCTCTGGTGCGAGAAACTCCTGTACCAAAAGAAACGGCAAAACGTCGAGGTT
TAAAATCAAATTCTGAAACACCTATTGCTCAAGTTTTGAAAACTTACTACACTCCTCAAGGTGGTAAACTCTCATTAGTT
CGGGTATGGCAAGGGGAAATTATTGATGGCATGATTTTAAATGGAGTGCGCATCGGTGGAATATATCGGTTGATGGGTCA
GCAAACAGAAAGTCTAGAGTTAGCTAAAACTGGAGAAATAGTTGCCCTCAGTCGGATGGAAGGTATACATACAGGTGATA
CTTTAACTATAGATGCAGATGGGAAAACTAAGTTGCCAAGAGTAATACTATTGCCTCCTGTTTTTGCTATGGCGATCGCT
CCGGAAAACCGTAAAGATGAAGTAAAAATGAGCAGCGCTTTAACAAAGTTGCTAGAAGAAGACCCGGCATTAATATGGGA
ACAACATGGGGATACTCACGAAGTCATCTTTTGGGGTCAAGGAGAAATTCATCTACAGGTAAGTTTAGAGCGTTTGCACC
GAAAGTATAATGTTTCGATGAAAACTTACTTACCCCGAGTTCCCTATAAAGAAACTATTCGGAAAAAGACTACTTCTCAT
GGTCGTTATAAACATCAAAGTGGGGGTCATGGGCAGTTTGGGGATGTGTATTTAGATATTCAACCGTTGCCACGGGGGTC
AGGTTTTAATTTTAGTGAAACTGTTGTCGGTGGAGTGGTGCCGAAGCAATATATTTCTGGTGTGGAAACAGGGGTGCGGG
AATATCTTCAACAGGGTCCTCTCGGTTTTCCCGTGGTTGATGTGGCGGTGACGTTGACTAATGGGTCGCATCATTCTGTT
GATAGTTCGGAGCAAGCATTTAAGCAGGCAGCGCGAGTGGCAATGCAGCAGGGAATGAGTGACTGCCAACCAGTATTGTT
GGAACCTATTGCTTTGGTGGATATTTTTGCACCTAATGAGTTTACTTCAAAAGTTTTGCAGTTAATTAGTATCCGTCGTG
GTCAGATATTGGGTTATGAAAGTATGACTGACTGGGAAAGGTGGGATAAGACTTCTGCTTATTTGGCTTTGTCAGAAATG
CAAGATTTAATTGTGGAGTTGCGATCGCAAACAATGGGAGTGGGTTCTTTTAATTGGCAATTTGATCATTTACAAGAAGT
GCCAAATAAGTTAGCTGAAAAGGTCTTGATCAAGAATGGTAATGGTAATGGTCGTGGTCATGGCTAA

Upstream 100 bases:

>100_bases
TAGCTTGTAGAGTATAAAAAAAATATATAAAATCTAACAAAAAAAGCTATTTTGTCAATTATCAATGCTGAATCATTAAG
CATTCGCCAGGAGGATAATT

Downstream 100 bases:

>100_bases
ACTACTTTAATATTTAAATGAAAAGTAGATATAGTTTAATTATTAACAGGACTTATTCACAAGTACCTAGGAACCTGGTT
TTTTTATGGATGTCTATTGT

Product: elongation factor G

Products: GDP; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 688; Mature: 687

Protein sequence:

>688_residues
MSEKVASNVRNIAIVGPYLSGKTTLLESLLSITKAISRKGSVKDGNTIGDGSPEARDRSMTVEINAASTKYDGINFTFLD
CPGSIEFAQETNNALIGAGAAIVVCEPDPARVLTLAPLLKFLDDWEIPHIVFINKMDRVCRDETHCKSNFGEVLEALKTV
SNRPIVPHQYPIAKNNQLIGFIDLVTEQAYHYHPGAPSDPVTIPESLKVEEQAAREQMLEELANFDDNLLEELVENIEPP
TEEIVADIKMELSADLIVPVFVGVAEKDSGVRSLLDALVRETPVPKETAKRRGLKSNSETPIAQVLKTYYTPQGGKLSLV
RVWQGEIIDGMILNGVRIGGIYRLMGQQTESLELAKTGEIVALSRMEGIHTGDTLTIDADGKTKLPRVILLPPVFAMAIA
PENRKDEVKMSSALTKLLEEDPALIWEQHGDTHEVIFWGQGEIHLQVSLERLHRKYNVSMKTYLPRVPYKETIRKKTTSH
GRYKHQSGGHGQFGDVYLDIQPLPRGSGFNFSETVVGGVVPKQYISGVETGVREYLQQGPLGFPVVDVAVTLTNGSHHSV
DSSEQAFKQAARVAMQQGMSDCQPVLLEPIALVDIFAPNEFTSKVLQLISIRRGQILGYESMTDWERWDKTSAYLALSEM
QDLIVELRSQTMGVGSFNWQFDHLQEVPNKLAEKVLIKNGNGNGRGHG

Sequences:

>Translated_688_residues
MSEKVASNVRNIAIVGPYLSGKTTLLESLLSITKAISRKGSVKDGNTIGDGSPEARDRSMTVEINAASTKYDGINFTFLD
CPGSIEFAQETNNALIGAGAAIVVCEPDPARVLTLAPLLKFLDDWEIPHIVFINKMDRVCRDETHCKSNFGEVLEALKTV
SNRPIVPHQYPIAKNNQLIGFIDLVTEQAYHYHPGAPSDPVTIPESLKVEEQAAREQMLEELANFDDNLLEELVENIEPP
TEEIVADIKMELSADLIVPVFVGVAEKDSGVRSLLDALVRETPVPKETAKRRGLKSNSETPIAQVLKTYYTPQGGKLSLV
RVWQGEIIDGMILNGVRIGGIYRLMGQQTESLELAKTGEIVALSRMEGIHTGDTLTIDADGKTKLPRVILLPPVFAMAIA
PENRKDEVKMSSALTKLLEEDPALIWEQHGDTHEVIFWGQGEIHLQVSLERLHRKYNVSMKTYLPRVPYKETIRKKTTSH
GRYKHQSGGHGQFGDVYLDIQPLPRGSGFNFSETVVGGVVPKQYISGVETGVREYLQQGPLGFPVVDVAVTLTNGSHHSV
DSSEQAFKQAARVAMQQGMSDCQPVLLEPIALVDIFAPNEFTSKVLQLISIRRGQILGYESMTDWERWDKTSAYLALSEM
QDLIVELRSQTMGVGSFNWQFDHLQEVPNKLAEKVLIKNGNGNGRGHG
>Mature_687_residues
SEKVASNVRNIAIVGPYLSGKTTLLESLLSITKAISRKGSVKDGNTIGDGSPEARDRSMTVEINAASTKYDGINFTFLDC
PGSIEFAQETNNALIGAGAAIVVCEPDPARVLTLAPLLKFLDDWEIPHIVFINKMDRVCRDETHCKSNFGEVLEALKTVS
NRPIVPHQYPIAKNNQLIGFIDLVTEQAYHYHPGAPSDPVTIPESLKVEEQAAREQMLEELANFDDNLLEELVENIEPPT
EEIVADIKMELSADLIVPVFVGVAEKDSGVRSLLDALVRETPVPKETAKRRGLKSNSETPIAQVLKTYYTPQGGKLSLVR
VWQGEIIDGMILNGVRIGGIYRLMGQQTESLELAKTGEIVALSRMEGIHTGDTLTIDADGKTKLPRVILLPPVFAMAIAP
ENRKDEVKMSSALTKLLEEDPALIWEQHGDTHEVIFWGQGEIHLQVSLERLHRKYNVSMKTYLPRVPYKETIRKKTTSHG
RYKHQSGGHGQFGDVYLDIQPLPRGSGFNFSETVVGGVVPKQYISGVETGVREYLQQGPLGFPVVDVAVTLTNGSHHSVD
SSEQAFKQAARVAMQQGMSDCQPVLLEPIALVDIFAPNEFTSKVLQLISIRRGQILGYESMTDWERWDKTSAYLALSEMQ
DLIVELRSQTMGVGSFNWQFDHLQEVPNKLAEKVLIKNGNGNGRGHG

Specific function: This Protein Promotes The GTP-Dependent Translocation Of The Nascent Protein Chain From The A-Site To The P-Site Of The Ribosome. [C]

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=701, Percent_Identity=29.1012838801712, Blast_Score=282, Evalue=7e-76,
Organism=Homo sapiens, GI19923640, Length=710, Percent_Identity=24.7887323943662, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI25306283, Length=389, Percent_Identity=25.9640102827763, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI25306287, Length=281, Percent_Identity=25.6227758007117, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1789738, Length=711, Percent_Identity=32.0675105485232, Blast_Score=325, Evalue=7e-90,
Organism=Escherichia coli, GI1790835, Length=471, Percent_Identity=23.7791932059448, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17533571, Length=683, Percent_Identity=28.8433382137628, Blast_Score=275, Evalue=6e-74,
Organism=Caenorhabditis elegans, GI17556745, Length=695, Percent_Identity=23.1654676258993, Blast_Score=120, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6323098, Length=687, Percent_Identity=31.2954876273654, Blast_Score=288, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6322359, Length=783, Percent_Identity=23.7547892720307, Blast_Score=164, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24582462, Length=686, Percent_Identity=31.7784256559767, Blast_Score=292, Evalue=6e-79,
Organism=Drosophila melanogaster, GI221458488, Length=737, Percent_Identity=24.1519674355495, Blast_Score=164, Evalue=1e-40,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 75995; Mature: 75864

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKVASNVRNIAIVGPYLSGKTTLLESLLSITKAISRKGSVKDGNTIGDGSPEARDRSM
CCCHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEE
TVEINAASTKYDGINFTFLDCPGSIEFAQETNNALIGAGAAIVVCEPDPARVLTLAPLLK
EEEEEECCCEECCEEEEEEECCCCCCHHHCCCCEEEECCEEEEEECCCCCHHHHHHHHHH
FLDDWEIPHIVFINKMDRVCRDETHCKSNFGEVLEALKTVSNRPIVPHQYPIAKNNQLIG
HHHCCCCCEEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEE
FIDLVTEQAYHYHPGAPSDPVTIPESLKVEEQAAREQMLEELANFDDNLLEELVENIEPP
HHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
TEEIVADIKMELSADLIVPVFVGVAEKDSGVRSLLDALVRETPVPKETAKRRGLKSNSET
HHHHHHHHHHHHCCCEEEEHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCC
PIAQVLKTYYTPQGGKLSLVRVWQGEIIDGMILNGVRIGGIYRLMGQQTESLELAKTGEI
HHHHHHHHHCCCCCCCEEEEEEECCCHHCCEEECCEEECHHHHHHCCCCCCEEHHCCCCE
VALSRMEGIHTGDTLTIDADGKTKLPRVILLPPVFAMAIAPENRKDEVKMSSALTKLLEE
EEEECCCCCCCCCEEEEECCCCCCCCEEEEECCHHHEEECCCCCHHHHHHHHHHHHHHHC
DPALIWEQHGDTHEVIFWGQGEIHLQVSLERLHRKYNVSMKTYLPRVPYKETIRKKTTSH
CCCEEEECCCCEEEEEEECCCEEEEEEEHHHHHHHHCCCHHHHCCCCCHHHHHHHHHCCC
GRYKHQSGGHGQFGDVYLDIQPLPRGSGFNFSETVVGGVVPKQYISGVETGVREYLQQGP
CCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
LGFPVVDVAVTLTNGSHHSVDSSEQAFKQAARVAMQQGMSDCQPVLLEPIALVDIFAPNE
CCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEECCCH
FTSKVLQLISIRRGQILGYESMTDWERWDKTSAYLALSEMQDLIVELRSQTMGVGSFNWQ
HHHHHHHHHHHHCCCEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FDHLQEVPNKLAEKVLIKNGNGNGRGHG
HHHHHHHHHHHHHHHEEECCCCCCCCCC
>Mature Secondary Structure 
SEKVASNVRNIAIVGPYLSGKTTLLESLLSITKAISRKGSVKDGNTIGDGSPEARDRSM
CCHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEE
TVEINAASTKYDGINFTFLDCPGSIEFAQETNNALIGAGAAIVVCEPDPARVLTLAPLLK
EEEEEECCCEECCEEEEEEECCCCCCHHHCCCCEEEECCEEEEEECCCCCHHHHHHHHHH
FLDDWEIPHIVFINKMDRVCRDETHCKSNFGEVLEALKTVSNRPIVPHQYPIAKNNQLIG
HHHCCCCCEEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEE
FIDLVTEQAYHYHPGAPSDPVTIPESLKVEEQAAREQMLEELANFDDNLLEELVENIEPP
HHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
TEEIVADIKMELSADLIVPVFVGVAEKDSGVRSLLDALVRETPVPKETAKRRGLKSNSET
HHHHHHHHHHHHCCCEEEEHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCC
PIAQVLKTYYTPQGGKLSLVRVWQGEIIDGMILNGVRIGGIYRLMGQQTESLELAKTGEI
HHHHHHHHHCCCCCCCEEEEEEECCCHHCCEEECCEEECHHHHHHCCCCCCEEHHCCCCE
VALSRMEGIHTGDTLTIDADGKTKLPRVILLPPVFAMAIAPENRKDEVKMSSALTKLLEE
EEEECCCCCCCCCEEEEECCCCCCCCEEEEECCHHHEEECCCCCHHHHHHHHHHHHHHHC
DPALIWEQHGDTHEVIFWGQGEIHLQVSLERLHRKYNVSMKTYLPRVPYKETIRKKTTSH
CCCEEEECCCCEEEEEEECCCEEEEEEEHHHHHHHHCCCHHHHCCCCCHHHHHHHHHCCC
GRYKHQSGGHGQFGDVYLDIQPLPRGSGFNFSETVVGGVVPKQYISGVETGVREYLQQGP
CCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
LGFPVVDVAVTLTNGSHHSVDSSEQAFKQAARVAMQQGMSDCQPVLLEPIALVDIFAPNE
CCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEECCCH
FTSKVLQLISIRRGQILGYESMTDWERWDKTSAYLALSEMQDLIVELRSQTMGVGSFNWQ
HHHHHHHHHHHHCCCEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FDHLQEVPNKLAEKVLIKNGNGNGRGHG
HHHHHHHHHHHHHHHEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]