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The map label for this gene is lktA [H]

Identifier: 113476310

GI number: 113476310

Start: 4196545

End: 4197528

Strand: Reverse

Name: lktA [H]

Synonym: Tery_2710

Alternate gene names: 113476310

Gene position: 4197528-4196545 (Counterclockwise)

Preceding gene: 113476311

Following gene: 113476309

Centisome position: 54.16

GC content: 45.22

Gene sequence:

>984_bases
GTGACTAGCTTAATTGACGGCAACATTAACGACCTAATTAATAATATCCCCGAAGAAGAACAACCTGATGGTGGATTTGA
TACACTCCCAACTGTAGACAGACCTATAGAAGGAGGAGATGGAGGCAGAGACATACAAGGAGGCCCAACAGCAGACGCTA
TTGAGGGATCTACTGCATCGGATGTTGTTTCAACAGGGGCTGGCGACGATCTAGTGGCAGCAGGTGATGGCGATGATGAT
GTTTTATTAGGTACTGGTGATGATACTGTATTGGCTGGTACTGGCGTTGACACCATCTCAGGTAACCAAGGAAATGACTC
CGTAGCTGGAGGTGCAGGAGATGATCTTCTCTATGGTGGTAAAGGTGATGATAGTGTAGAAGGTGGTGAAGGAGCAGACT
TTGTCTTCGGCGATCGCGGAAGTGACCTAGTACAAGGTGGGGCCGGAGATGACGTCGCACTGGGAGGGAGAGATTCTGAT
ACTGTAACGGGTGATGAAGGTAATGACACTCTAGATGGAGGTAAAGGGGATGACATTCTATCTGGAGGTGTAGGGGATGA
CTTCCTATTCGGTGGAAAGGGTAGTGATACTTTAACAGGTGGCACTGGAGCTGATAAATTCCTCTTCTATTATAATGAGG
ATGGTAGTTACGGACTTGACTCCTTAACAGACTTTAATAGGGATCAAGGAGATAAGATAGGTATAGTTGTTAATAACTTC
GGTGGCGGCAACTTTGAGGCTTTGACAGGAGCACGTCCTGGCGATTCATTATCAGGAGCACAGTTTGCGGTTGTTGAGAA
CTTTAGTCCTAATGAGGATGGAGCTAATTCAGCAGCAATCATCTATGACCCTGATACTGGTTTAGTATACTACAACCCAG
ACGGATCAGCAGTTGCAGGTAATGAAACTCCAATTGCTCGGGTTGATAATACTGTTTTTGATAGTAATAACCCATTACAA
GGTACTGACTTTGAAATCTTCTAA

Upstream 100 bases:

>100_bases
ATGAACGAAAAAGGTCATCTATACAGAATCTAAAAATTAGCTCTTTGAGCGAATAACACATAAATTAGCAATAGTAAACT
CTAAAAAACGAGGTAAGCAA

Downstream 100 bases:

>100_bases
GTCTAGTTATTAATTAATAAATATGATTTTAAATGTGGGTATAACCCAAAAATGAAGATACTGAGTCCCTCCTAACTTTA
GGGGGGAATTTTGTTTTAGC

Product: hemolysin-type calcium-binding protein

Products: NA

Alternate protein names: Lkt [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTSLIDGNINDLINNIPEEEQPDGGFDTLPTVDRPIEGGDGGRDIQGGPTADAIEGSTASDVVSTGAGDDLVAAGDGDDD
VLLGTGDDTVLAGTGVDTISGNQGNDSVAGGAGDDLLYGGKGDDSVEGGEGADFVFGDRGSDLVQGGAGDDVALGGRDSD
TVTGDEGNDTLDGGKGDDILSGGVGDDFLFGGKGSDTLTGGTGADKFLFYYNEDGSYGLDSLTDFNRDQGDKIGIVVNNF
GGGNFEALTGARPGDSLSGAQFAVVENFSPNEDGANSAAIIYDPDTGLVYYNPDGSAVAGNETPIARVDNTVFDSNNPLQ
GTDFEIF

Sequences:

>Translated_327_residues
MTSLIDGNINDLINNIPEEEQPDGGFDTLPTVDRPIEGGDGGRDIQGGPTADAIEGSTASDVVSTGAGDDLVAAGDGDDD
VLLGTGDDTVLAGTGVDTISGNQGNDSVAGGAGDDLLYGGKGDDSVEGGEGADFVFGDRGSDLVQGGAGDDVALGGRDSD
TVTGDEGNDTLDGGKGDDILSGGVGDDFLFGGKGSDTLTGGTGADKFLFYYNEDGSYGLDSLTDFNRDQGDKIGIVVNNF
GGGNFEALTGARPGDSLSGAQFAVVENFSPNEDGANSAAIIYDPDTGLVYYNPDGSAVAGNETPIARVDNTVFDSNNPLQ
GTDFEIF
>Mature_326_residues
TSLIDGNINDLINNIPEEEQPDGGFDTLPTVDRPIEGGDGGRDIQGGPTADAIEGSTASDVVSTGAGDDLVAAGDGDDDV
LLGTGDDTVLAGTGVDTISGNQGNDSVAGGAGDDLLYGGKGDDSVEGGEGADFVFGDRGSDLVQGGAGDDVALGGRDSDT
VTGDEGNDTLDGGKGDDILSGGVGDDFLFGGKGSDTLTGGTGADKFLFYYNEDGSYGLDSLTDFNRDQGDKIGIVVNNFG
GGNFEALTGARPGDSLSGAQFAVVENFSPNEDGANSAAIIYDPDTGLVYYNPDGSAVAGNETPIARVDNTVFDSNNPLQG
TDFEIF

Specific function: One of the virulence factors of A.actinomycetemcomitans might be a cytotoxin, possibly the membrane-bound hemolysin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein. Secreted (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 7 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR018504
- InterPro:   IPR003995
- InterPro:   IPR011049 [H]

Pfam domain/function: PF00353 HemolysinCabind; PF02382 RTX [H]

EC number: NA

Molecular weight: Translated: 32863; Mature: 32732

Theoretical pI: Translated: 3.31; Mature: 3.31

Prosite motif: PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLIDGNINDLINNIPEEEQPDGGFDTLPTVDRPIEGGDGGRDIQGGPTADAIEGSTAS
CCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
DVVSTGAGDDLVAAGDGDDDVLLGTGDDTVLAGTGVDTISGNQGNDSVAGGAGDDLLYGG
HHHHCCCCCCEEEECCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEECC
KGDDSVEGGEGADFVFGDRGSDLVQGGAGDDVALGGRDSDTVTGDEGNDTLDGGKGDDIL
CCCCCCCCCCCCEEEECCCCCHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEE
SGGVGDDFLFGGKGSDTLTGGTGADKFLFYYNEDGSYGLDSLTDFNRDQGDKIGIVVNNF
ECCCCCCEEECCCCCCCEECCCCCCEEEEEECCCCCCCCCHHHHCCCCCCCEEEEEEECC
GGGNFEALTGARPGDSLSGAQFAVVENFSPNEDGANSAAIIYDPDTGLVYYNPDGSAVAG
CCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCEEEECCCCCEECC
NETPIARVDNTVFDSNNPLQGTDFEIF
CCCCCEEECCEEECCCCCCCCCCCEEC
>Mature Secondary Structure 
TSLIDGNINDLINNIPEEEQPDGGFDTLPTVDRPIEGGDGGRDIQGGPTADAIEGSTAS
CCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
DVVSTGAGDDLVAAGDGDDDVLLGTGDDTVLAGTGVDTISGNQGNDSVAGGAGDDLLYGG
HHHHCCCCCCEEEECCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEECC
KGDDSVEGGEGADFVFGDRGSDLVQGGAGDDVALGGRDSDTVTGDEGNDTLDGGKGDDIL
CCCCCCCCCCCCEEEECCCCCHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEE
SGGVGDDFLFGGKGSDTLTGGTGADKFLFYYNEDGSYGLDSLTDFNRDQGDKIGIVVNNF
ECCCCCCEEECCCCCCCEECCCCCCEEEEEECCCCCCCCCHHHHCCCCCCCEEEEEEECC
GGGNFEALTGARPGDSLSGAQFAVVENFSPNEDGANSAAIIYDPDTGLVYYNPDGSAVAG
CCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCEEEECCCCCEECC
NETPIARVDNTVFDSNNPLQGTDFEIF
CCCCCEEECCEEECCCCCCCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2670940 [H]