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The map label for this gene is uvrB [H]

Identifier: 113476281

GI number: 113476281

Start: 4147239

End: 4149272

Strand: Reverse

Name: uvrB [H]

Synonym: Tery_2678

Alternate gene names: 113476281

Gene position: 4149272-4147239 (Counterclockwise)

Preceding gene: 113476282

Following gene: 113476279

Centisome position: 53.54

GC content: 36.63

Gene sequence:

>2034_bases
ATGAAGAATGGTACAATTAATTTTAAAATAATCATGAAAAAATTTTGTTTGCAAGCTCCCTTTCAACCTACTGGTGACCA
ACCTCAAGCGATCGCTCAGTTAACTACCAATATTCAAGCTGGGCATAATTTTCAAACCTTACTTGGAGCTACTGGTACAG
GTAAGACATTTTCTATAGCTTCTGTCATAGAAAATGTTGGTAGACCGACGTTAGTTTTGGCTCATAACAAAACATTGGCT
GCTCAATTATGTAATGAATTAAGGGATTTTTTTCCTGATAATTCTGTGGAATATTTTATTAGTTATTATGACTATTATCA
ACCGGAGGCTTATATTCCGGTAACGGATACATATATAGAAAAAACAGCTTCTATTAATGATGAAATTGATATGTTGCGTC
ACTCAGCAACTAGGTCACTTTTTGAACGTCGAGATGTAATTGTGGTAGCTTCTATTAGTTGTATTTACGGTTTAGGAATT
CCGTCAGAATATTTAAAAGCAGCTATTTCTTTACAAGTGGGAGAAGAAATTAATCAACGACAAATTTTGAGAGATTTAGC
AACAGTTCAATATACTAGAAATGATTTGAATTTAGGTCGAGGAAAATTTAGAGTTAAGGGTGATGTTTTGGAAATCGGAC
CTGCTTATGAGGATAGAATTATTCGGGTAGAATTTTTTGGAGATGAAATAGATGCTATTCGTTATATTGACCCTGTAACT
GGAAATATTCTCCAAAGTTTAGAGTCTTTAAATGTATATCCGGCGCGTCACTTTGTTACTCCTGAAGAAAGATTAGAAAT
TGCTTGTAATGATATTGAAGTAGAATTAGATGAGAGATTAAAAGAATTAGAAAAAGCCGGAAAGTTGTTAGAAGCTCAAC
GTTTAGAACAGCGTTCCAGATACGATATAGAAATGTTACGGGAGGTGGGATATTGCAATGGAGTGGAAAATTATTCTCGG
CATTTAGTGGGTAGAAAAGCAGGGGAACCGCCGGAATGTTTGATTGATTATTTTCCGAAAGATTGGTTATTAGTTATTGA
TGAATCTCATGTGACTGTTCCCCAAATTCGAGGAATGTATAATGGAGACCAAGCTAGGAAAAAAGTTTTAGTTGAACATG
GGTTTCGTTTGCCTAGTGCTACGGATAATAGACCTTTAAAATCTGAGGAATTTTGGGAAAAGGTTAATCAATGTATTTTG
GTTTCTGCTACTCCTGGAAATTGGGAAATAGAAAAATCTGAGGATAGAATTGTTGAGCAAATTATTCGTCCGACTGGTGT
TGTTGATCCGAAAATTTTTGTGCGTCCGACTGAAGGTCAAATTGATGATTTATTGGGTGAAATTAGGGAACGGGTTAAGC
TGGAAGAGAGGGTTTTAATTACGACTTTAACTAAGCGGATGGCTGAAGATTTGACTGAATATTTAGAGGATCAAAGTGTT
AAGGTTCGTTATTTGCATTCGGAGATTAATTCTATTAAGAGAATTGAGATTTTACAGGGGTTGAGAGAGGGAGAGTTTGA
TGTGTTAATTGGGGTGAATTTATTACGGGAAGGTTTGGATTTGCCGGAGGTTTCTTTGGTGGCTATTTTAGATGCGGATA
AGGAGGGATTTTTACGGGCGGAACGTTCTTTAATTCAGACTATTGGTAGGGCGGCGCGTCATATCCGAGGTCAGGCTATT
TTATATGCTGATAATTTGACGGATAGTATGATTAAGGCTATTGATGAAACTGAAAGAAGGCGAGGTATTCAGTTGGCATA
TAATAAGATGAATAATATTACGCCACGGCCTGTTGTGAAAAAACAAAGTAATGCTATTTTGGCGTTTTTGGATGTGTCGC
GCCGTTTAAATTCTCAACAGTTGGAAGAGGTTTATGAACAGGTGGATAATTTGTCTTTGGATGATGTTCCGGAGTGGATT
AAAAAGTTAGAAAGTCAGATGAAGGAAGCGGCGAAAAATTTGGAGTTTGAAGAGGCGGCTAAGTTACGCGATCGCATTAA
ACATTTGCGGGATAAGTTAGTCGGTAATTCTTGA

Upstream 100 bases:

>100_bases
TTGCAGTTGAGTGAAATATCCGCGCTTTCAGGCTAGAAAGTGGGTCAATGTGCGATTTTTTTTCCTTCTTTTCATCCTAA
TTTGACGAATTCAAGATACC

Downstream 100 bases:

>100_bases
AATTTATCAAAAAAAAAGTTTGCTTGCTCAAAATAATTGGGTCTAAAGCCTCATTTTTGAAGGCTAAATATTATTAGGTT
AGGGTTTGCTAAAAAAGTCT

Product: excinuclease ABC subunit B

Products: NA

Alternate protein names: Protein uvrB; Excinuclease ABC subunit B [H]

Number of amino acids: Translated: 677; Mature: 677

Protein sequence:

>677_residues
MKNGTINFKIIMKKFCLQAPFQPTGDQPQAIAQLTTNIQAGHNFQTLLGATGTGKTFSIASVIENVGRPTLVLAHNKTLA
AQLCNELRDFFPDNSVEYFISYYDYYQPEAYIPVTDTYIEKTASINDEIDMLRHSATRSLFERRDVIVVASISCIYGLGI
PSEYLKAAISLQVGEEINQRQILRDLATVQYTRNDLNLGRGKFRVKGDVLEIGPAYEDRIIRVEFFGDEIDAIRYIDPVT
GNILQSLESLNVYPARHFVTPEERLEIACNDIEVELDERLKELEKAGKLLEAQRLEQRSRYDIEMLREVGYCNGVENYSR
HLVGRKAGEPPECLIDYFPKDWLLVIDESHVTVPQIRGMYNGDQARKKVLVEHGFRLPSATDNRPLKSEEFWEKVNQCIL
VSATPGNWEIEKSEDRIVEQIIRPTGVVDPKIFVRPTEGQIDDLLGEIRERVKLEERVLITTLTKRMAEDLTEYLEDQSV
KVRYLHSEINSIKRIEILQGLREGEFDVLIGVNLLREGLDLPEVSLVAILDADKEGFLRAERSLIQTIGRAARHIRGQAI
LYADNLTDSMIKAIDETERRRGIQLAYNKMNNITPRPVVKKQSNAILAFLDVSRRLNSQQLEEVYEQVDNLSLDDVPEWI
KKLESQMKEAAKNLEFEEAAKLRDRIKHLRDKLVGNS

Sequences:

>Translated_677_residues
MKNGTINFKIIMKKFCLQAPFQPTGDQPQAIAQLTTNIQAGHNFQTLLGATGTGKTFSIASVIENVGRPTLVLAHNKTLA
AQLCNELRDFFPDNSVEYFISYYDYYQPEAYIPVTDTYIEKTASINDEIDMLRHSATRSLFERRDVIVVASISCIYGLGI
PSEYLKAAISLQVGEEINQRQILRDLATVQYTRNDLNLGRGKFRVKGDVLEIGPAYEDRIIRVEFFGDEIDAIRYIDPVT
GNILQSLESLNVYPARHFVTPEERLEIACNDIEVELDERLKELEKAGKLLEAQRLEQRSRYDIEMLREVGYCNGVENYSR
HLVGRKAGEPPECLIDYFPKDWLLVIDESHVTVPQIRGMYNGDQARKKVLVEHGFRLPSATDNRPLKSEEFWEKVNQCIL
VSATPGNWEIEKSEDRIVEQIIRPTGVVDPKIFVRPTEGQIDDLLGEIRERVKLEERVLITTLTKRMAEDLTEYLEDQSV
KVRYLHSEINSIKRIEILQGLREGEFDVLIGVNLLREGLDLPEVSLVAILDADKEGFLRAERSLIQTIGRAARHIRGQAI
LYADNLTDSMIKAIDETERRRGIQLAYNKMNNITPRPVVKKQSNAILAFLDVSRRLNSQQLEEVYEQVDNLSLDDVPEWI
KKLESQMKEAAKNLEFEEAAKLRDRIKHLRDKLVGNS
>Mature_677_residues
MKNGTINFKIIMKKFCLQAPFQPTGDQPQAIAQLTTNIQAGHNFQTLLGATGTGKTFSIASVIENVGRPTLVLAHNKTLA
AQLCNELRDFFPDNSVEYFISYYDYYQPEAYIPVTDTYIEKTASINDEIDMLRHSATRSLFERRDVIVVASISCIYGLGI
PSEYLKAAISLQVGEEINQRQILRDLATVQYTRNDLNLGRGKFRVKGDVLEIGPAYEDRIIRVEFFGDEIDAIRYIDPVT
GNILQSLESLNVYPARHFVTPEERLEIACNDIEVELDERLKELEKAGKLLEAQRLEQRSRYDIEMLREVGYCNGVENYSR
HLVGRKAGEPPECLIDYFPKDWLLVIDESHVTVPQIRGMYNGDQARKKVLVEHGFRLPSATDNRPLKSEEFWEKVNQCIL
VSATPGNWEIEKSEDRIVEQIIRPTGVVDPKIFVRPTEGQIDDLLGEIRERVKLEERVLITTLTKRMAEDLTEYLEDQSV
KVRYLHSEINSIKRIEILQGLREGEFDVLIGVNLLREGLDLPEVSLVAILDADKEGFLRAERSLIQTIGRAARHIRGQAI
LYADNLTDSMIKAIDETERRRGIQLAYNKMNNITPRPVVKKQSNAILAFLDVSRRLNSQQLEEVYEQVDNLSLDDVPEWI
KKLESQMKEAAKNLEFEEAAKLRDRIKHLRDKLVGNS

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. Upon binding of the uvrA(2)B(2) complex to a putative damaged site, the DNA

COG id: COG0556

COG function: function code L; Helicase subunit of the DNA excision repair complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI1786996, Length=671, Percent_Identity=56.7809239940387, Blast_Score=754, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR001943
- InterPro:   IPR004807
- InterPro:   IPR009055 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 77424; Mature: 77424

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50151 UVR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNGTINFKIIMKKFCLQAPFQPTGDQPQAIAQLTTNIQAGHNFQTLLGATGTGKTFSIA
CCCCCEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCEEHH
SVIENVGRPTLVLAHNKTLAAQLCNELRDFFPDNSVEYFISYYDYYQPEAYIPVTDTYIE
HHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEECCCHHHHH
KTASINDEIDMLRHSATRSLFERRDVIVVASISCIYGLGIPSEYLKAAISLQVGEEINQR
HHCCCCHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
QILRDLATVQYTRNDLNLGRGKFRVKGDVLEIGPAYEDRIIRVEFFGDEIDAIRYIDPVT
HHHHHHHHHHHHCCCCCCCCCEEEEECCEEECCCCCCCCEEEEEEECCCCCHHHHCCCCH
GNILQSLESLNVYPARHFVTPEERLEIACNDIEVELDERLKELEKAGKLLEAQRLEQRSR
HHHHHHHHHCCCCCCHHCCCHHHHHEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHC
YDIEMLREVGYCNGVENYSRHLVGRKAGEPPECLIDYFPKDWLLVIDESHVTVPQIRGMY
CHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEEECCCCCHHHHCCCC
NGDQARKKVLVEHGFRLPSATDNRPLKSEEFWEKVNQCILVSATPGNWEIEKSEDRIVEQ
CCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCEEEEEECCCCCEEECHHHHHHHH
IIRPTGVVDPKIFVRPTEGQIDDLLGEIRERVKLEERVLITTLTKRMAEDLTEYLEDQSV
HHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
KVRYLHSEINSIKRIEILQGLREGEFDVLIGVNLLREGLDLPEVSLVAILDADKEGFLRA
EEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCCCCEEEEEEEECCCHHHHHH
ERSLIQTIGRAARHIRGQAILYADNLTDSMIKAIDETERRRGIQLAYNKMNNITPRPVVK
HHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCC
KQSNAILAFLDVSRRLNSQQLEEVYEQVDNLSLDDVPEWIKKLESQMKEAAKNLEFEEAA
CCCCCEEEEEEHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
KLRDRIKHLRDKLVGNS
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNGTINFKIIMKKFCLQAPFQPTGDQPQAIAQLTTNIQAGHNFQTLLGATGTGKTFSIA
CCCCCEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCEEHH
SVIENVGRPTLVLAHNKTLAAQLCNELRDFFPDNSVEYFISYYDYYQPEAYIPVTDTYIE
HHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEECCCHHHHH
KTASINDEIDMLRHSATRSLFERRDVIVVASISCIYGLGIPSEYLKAAISLQVGEEINQR
HHCCCCHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
QILRDLATVQYTRNDLNLGRGKFRVKGDVLEIGPAYEDRIIRVEFFGDEIDAIRYIDPVT
HHHHHHHHHHHHCCCCCCCCCEEEEECCEEECCCCCCCCEEEEEEECCCCCHHHHCCCCH
GNILQSLESLNVYPARHFVTPEERLEIACNDIEVELDERLKELEKAGKLLEAQRLEQRSR
HHHHHHHHHCCCCCCHHCCCHHHHHEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHC
YDIEMLREVGYCNGVENYSRHLVGRKAGEPPECLIDYFPKDWLLVIDESHVTVPQIRGMY
CHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEEECCCCCHHHHCCCC
NGDQARKKVLVEHGFRLPSATDNRPLKSEEFWEKVNQCILVSATPGNWEIEKSEDRIVEQ
CCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCEEEEEECCCCCEEECHHHHHHHH
IIRPTGVVDPKIFVRPTEGQIDDLLGEIRERVKLEERVLITTLTKRMAEDLTEYLEDQSV
HHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
KVRYLHSEINSIKRIEILQGLREGEFDVLIGVNLLREGLDLPEVSLVAILDADKEGFLRA
EEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCCCCEEEEEEEECCCHHHHHH
ERSLIQTIGRAARHIRGQAILYADNLTDSMIKAIDETERRRGIQLAYNKMNNITPRPVVK
HHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCC
KQSNAILAFLDVSRRLNSQQLEEVYEQVDNLSLDDVPEWIKKLESQMKEAAKNLEFEEAA
CCCCCEEEEEEHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
KLRDRIKHLRDKLVGNS
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]