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The map label for this gene is sppA [C]

Identifier: 113476113

GI number: 113476113

Start: 3842471

End: 3843289

Strand: Reverse

Name: sppA [C]

Synonym: Tery_2494

Alternate gene names: 113476113

Gene position: 3843289-3842471 (Counterclockwise)

Preceding gene: 113476116

Following gene: 113476112

Centisome position: 49.59

GC content: 39.44

Gene sequence:

>819_bases
ATGATTTGGCCATTTAAGCCCCGATATCGTAAACAAATTGCCCGAATAGAGATTAATGGTGTCATTGCCAGCGAGACCCG
AAAACAAGTGTTAGAAGCACTTAAAACAGTAGAAGAAAGAAAATTTCCGGCCCTATTACTTAGGATAGATAGTCCCGGAG
GTACTGTAGCGGACTCTCAAGAAATCTACAATGCCCTGAAAAAGCTGCAAGAGAAAGTAAAAATTGTCGCGAGCTTCGGC
AATATTTCTGCCTCTGGTGGTGTTTATATTGGTATGGGTGCTCAAAACATAATGTCCAATCCGGGGACGATAACTGGTAG
TATTGGGGTAATTTTGCGAGGCAATAATATAGAACGTCTATTAGAAAAAGTAGGGGTTTCTTTTAAGGTAGTAAAATCTG
GGCCTTATAAAGATATATTAGCCTTTGACCGGGAAATGACTGCTCCAGAAAAGCAAATTCTCCAAGATCTAATAGATTTT
AGTTATCAGCAATTTGTCCAAACAGTGGCTGAAGCGCGAAATTTAGCTGTAGAAACTGTTAAAAGTTTTGCAGATGGTCG
TATCTTTACTGGACAACAAGCATTAGAATTAGGGGTAGTAGACCGTTTAGGTACAGAAGAAGATGCTAGGAAATGGGCCT
GTAATCTGGTGGACTTAGACCCAGAAAAAACCGAGAGTTTTACTCTAGAAAAACCCAAAACTTTCTTAAATAAAGTTTTG
AACAATAATCAGGTATCATCAAAATTATCGGCTGCTCAAAGCTGGGTGGAATTTGAAGTTTCTACCAGTGGCTTACCTTT
GTGGCTGTATCGACCTTAA

Upstream 100 bases:

>100_bases
TTGACAATTTCACTTGAATATGCTATGAGCTAAAAAAATTTATTGCTTATTGCTTATTATTTTTGCCTTTTGTATTTTGA
CTTAAGAGAAAAAAAACAGG

Downstream 100 bases:

>100_bases
ATTTAACTATAAAGCTTTTAATGGGGAGGATTTTAGTGTGGTGTGGCGAGTTCAAGCAATTCGTGGAGCAACTACAGTCT
CAGAAAATTCTGTAGAGGCA

Product: signal peptide peptidase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MIWPFKPRYRKQIARIEINGVIASETRKQVLEALKTVEERKFPALLLRIDSPGGTVADSQEIYNALKKLQEKVKIVASFG
NISASGGVYIGMGAQNIMSNPGTITGSIGVILRGNNIERLLEKVGVSFKVVKSGPYKDILAFDREMTAPEKQILQDLIDF
SYQQFVQTVAEARNLAVETVKSFADGRIFTGQQALELGVVDRLGTEEDARKWACNLVDLDPEKTESFTLEKPKTFLNKVL
NNNQVSSKLSAAQSWVEFEVSTSGLPLWLYRP

Sequences:

>Translated_272_residues
MIWPFKPRYRKQIARIEINGVIASETRKQVLEALKTVEERKFPALLLRIDSPGGTVADSQEIYNALKKLQEKVKIVASFG
NISASGGVYIGMGAQNIMSNPGTITGSIGVILRGNNIERLLEKVGVSFKVVKSGPYKDILAFDREMTAPEKQILQDLIDF
SYQQFVQTVAEARNLAVETVKSFADGRIFTGQQALELGVVDRLGTEEDARKWACNLVDLDPEKTESFTLEKPKTFLNKVL
NNNQVSSKLSAAQSWVEFEVSTSGLPLWLYRP
>Mature_272_residues
MIWPFKPRYRKQIARIEINGVIASETRKQVLEALKTVEERKFPALLLRIDSPGGTVADSQEIYNALKKLQEKVKIVASFG
NISASGGVYIGMGAQNIMSNPGTITGSIGVILRGNNIERLLEKVGVSFKVVKSGPYKDILAFDREMTAPEKQILQDLIDF
SYQQFVQTVAEARNLAVETVKSFADGRIFTGQQALELGVVDRLGTEEDARKWACNLVDLDPEKTESFTLEKPKTFLNKVL
NNNQVSSKLSAAQSWVEFEVSTSGLPLWLYRP

Specific function: Digestion Of The Cleaved Signal Peptides. This Activity Is Necessary To Maintain Proper Secretion Of Mature Proteins Across The Membrane. [C]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=204, Percent_Identity=35.7843137254902, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787527, Length=166, Percent_Identity=30.7228915662651, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 30285; Mature: 30285

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIWPFKPRYRKQIARIEINGVIASETRKQVLEALKTVEERKFPALLLRIDSPGGTVADSQ
CCCCCCHHHHHHHHHEEECCEEHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHH
EIYNALKKLQEKVKIVASFGNISASGGVYIGMGAQNIMSNPGTITGSIGVILRGNNIERL
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHCCCCEEEECEEEEEECCCHHHH
LEKVGVSFKVVKSGPYKDILAFDREMTAPEKQILQDLIDFSYQQFVQTVAEARNLAVETV
HHHHCCEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSFADGRIFTGQQALELGVVDRLGTEEDARKWACNLVDLDPEKTESFTLEKPKTFLNKVL
HHHHCCCEECCHHHHHHHHHHHCCCHHHHHHHCCCCEECCCCCCCCEECCCHHHHHHHHH
NNNQVSSKLSAAQSWVEFEVSTSGLPLWLYRP
CCCHHHHHHHHHHHHHEEEEECCCCCEEEECC
>Mature Secondary Structure
MIWPFKPRYRKQIARIEINGVIASETRKQVLEALKTVEERKFPALLLRIDSPGGTVADSQ
CCCCCCHHHHHHHHHEEECCEEHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHH
EIYNALKKLQEKVKIVASFGNISASGGVYIGMGAQNIMSNPGTITGSIGVILRGNNIERL
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHCCCCEEEECEEEEEECCCHHHH
LEKVGVSFKVVKSGPYKDILAFDREMTAPEKQILQDLIDFSYQQFVQTVAEARNLAVETV
HHHHCCEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSFADGRIFTGQQALELGVVDRLGTEEDARKWACNLVDLDPEKTESFTLEKPKTFLNKVL
HHHHCCCEECCHHHHHHHHHHHCCCHHHHHHHCCCCEECCCCCCCCEECCCHHHHHHHHH
NNNQVSSKLSAAQSWVEFEVSTSGLPLWLYRP
CCCHHHHHHHHHHHHHEEEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]