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The map label for this gene is lldD [H]

Identifier: 113476107

GI number: 113476107

Start: 3834377

End: 3835534

Strand: Reverse

Name: lldD [H]

Synonym: Tery_2488

Alternate gene names: 113476107

Gene position: 3835534-3834377 (Counterclockwise)

Preceding gene: 113476108

Following gene: 113476102

Centisome position: 49.49

GC content: 44.73

Gene sequence:

>1158_bases
ATGAAATTGAATGACTGTCACAATTTTCAGGATTTCCGAAAATTAGCAAAACGCAGATTACCAGGACCAATTTTTGATTA
CATTGATGGAGCTGCCGATGATGAACAGAGCTATCGGCGTAACACTGAAGCCTATGGAGAATGCGATCTTATTCCGAACG
TGCTTGTCGGTGTGGAGAATGTGGATATGTCAGTTGAAGTGATGGGGCAAAAACTAGACATGCCTATCTACTGTGCTCCG
ACAGCATTGCAACGCCTTTTTCATCACGAAGGAGAGCGTGCGGTTGCGAGAGCTGCTGCAAAATATGGCACAATGTTTGG
AGTGTCTTCACTGGCGACAGTAACTGTTGAAGAGATCGCAGAGATTACAAACACTCCAAAGATGTTTCAGTTCTACTTCC
ATAAAGACCGCGGCTTAAATGATGCGTTGCTTGAACGTGCACGAGCTGCGAACTTTAATGTGTTGGCATTAACCGTCGAT
ACGATTACTGGTGGTAATCGCGAACGTGATTTACGTACAGGATTTACCTCACCACCAAAATTAACACTAGGCTCCTTTAT
GAGTTTTGCGACTCACCCTGCATGGGCTTGGAACTTTTTGACAAAAGAAAAGTTCGATATGCCGCATTTGTCTGGGTATG
TCTCCCAGGGAACGAATTTAGCAGTCTCTGTTGGTGATTATTTTTCAACGATGCTAGATCAATCCATGAATTGGAATGAT
GCTGAAAAACTCTGCGCACAGTGGAACGGGCAGTTTGCACTGAAAGGGATAATGAGTGTGGAAGATGCCAAGCGTGCTAT
TGATATTGGTTGTACGGGTATTATAGTTTCTAACCACGGTGGCCGTCAGCTTGATGGTTCCCGTAGCCCCTTCGATCAAC
TCGCAGAAATTTGTGATGCTGTTGGGGATAAAATTGATGTCATTTGCGAAGGTGGTATTCAGCGCGGTACGCATGTGCTC
AAGGCTCTATCTGTTGGAGCTAAAGCATGTTCAGGTGGGCGATTATATCTTTATGCATTGGCTGCTGCTGGGAGGGCAGG
AGTTGAGCGTGTTTTAGGTAATATGCGCACTGAAATTGAGCGTGATATGAAATTGATGGGAGTGACCAAGCTGGATCAAT
TGAGTAGAGATAATCTACGCTTTCATCACTCACGATGA

Upstream 100 bases:

>100_bases
GAACAGTTCATTCTCTAGAGACTGGCGATGAAGGTTGAATATTTCTCAAAATGGAATAGTATGAACTGCTTAGTAAACAT
AAATCTCACTGAGGTATTTT

Downstream 100 bases:

>100_bases
GGCTGCGTAGGGTGGGCAAGATATAATGAAAGAATTGAGAATTTTCCTCCATAGGCTTACCTACCCTATAAATCTACCGA
GAAAGAGCCATCTTCCCAAC

Product: L-lactate dehydrogenase (cytochrome)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MKLNDCHNFQDFRKLAKRRLPGPIFDYIDGAADDEQSYRRNTEAYGECDLIPNVLVGVENVDMSVEVMGQKLDMPIYCAP
TALQRLFHHEGERAVARAAAKYGTMFGVSSLATVTVEEIAEITNTPKMFQFYFHKDRGLNDALLERARAANFNVLALTVD
TITGGNRERDLRTGFTSPPKLTLGSFMSFATHPAWAWNFLTKEKFDMPHLSGYVSQGTNLAVSVGDYFSTMLDQSMNWND
AEKLCAQWNGQFALKGIMSVEDAKRAIDIGCTGIIVSNHGGRQLDGSRSPFDQLAEICDAVGDKIDVICEGGIQRGTHVL
KALSVGAKACSGGRLYLYALAAAGRAGVERVLGNMRTEIERDMKLMGVTKLDQLSRDNLRFHHSR

Sequences:

>Translated_385_residues
MKLNDCHNFQDFRKLAKRRLPGPIFDYIDGAADDEQSYRRNTEAYGECDLIPNVLVGVENVDMSVEVMGQKLDMPIYCAP
TALQRLFHHEGERAVARAAAKYGTMFGVSSLATVTVEEIAEITNTPKMFQFYFHKDRGLNDALLERARAANFNVLALTVD
TITGGNRERDLRTGFTSPPKLTLGSFMSFATHPAWAWNFLTKEKFDMPHLSGYVSQGTNLAVSVGDYFSTMLDQSMNWND
AEKLCAQWNGQFALKGIMSVEDAKRAIDIGCTGIIVSNHGGRQLDGSRSPFDQLAEICDAVGDKIDVICEGGIQRGTHVL
KALSVGAKACSGGRLYLYALAAAGRAGVERVLGNMRTEIERDMKLMGVTKLDQLSRDNLRFHHSR
>Mature_385_residues
MKLNDCHNFQDFRKLAKRRLPGPIFDYIDGAADDEQSYRRNTEAYGECDLIPNVLVGVENVDMSVEVMGQKLDMPIYCAP
TALQRLFHHEGERAVARAAAKYGTMFGVSSLATVTVEEIAEITNTPKMFQFYFHKDRGLNDALLERARAANFNVLALTVD
TITGGNRERDLRTGFTSPPKLTLGSFMSFATHPAWAWNFLTKEKFDMPHLSGYVSQGTNLAVSVGDYFSTMLDQSMNWND
AEKLCAQWNGQFALKGIMSVEDAKRAIDIGCTGIIVSNHGGRQLDGSRSPFDQLAEICDAVGDKIDVICEGGIQRGTHVL
KALSVGAKACSGGRLYLYALAAAGRAGVERVLGNMRTEIERDMKLMGVTKLDQLSRDNLRFHHSR

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=377, Percent_Identity=35.5437665782493, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI54234014, Length=377, Percent_Identity=33.1564986737401, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI7705393, Length=377, Percent_Identity=33.1564986737401, Blast_Score=186, Evalue=3e-47,
Organism=Escherichia coli, GI1790033, Length=371, Percent_Identity=36.1185983827493, Blast_Score=248, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI193208036, Length=380, Percent_Identity=33.6842105263158, Blast_Score=215, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI32566217, Length=279, Percent_Identity=34.4086021505376, Blast_Score=157, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6323587, Length=391, Percent_Identity=34.5268542199489, Blast_Score=211, Evalue=2e-55,
Organism=Drosophila melanogaster, GI78707188, Length=377, Percent_Identity=33.9522546419098, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI281363140, Length=377, Percent_Identity=33.9522546419098, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI78707190, Length=377, Percent_Identity=33.9522546419098, Blast_Score=213, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 42621; Mature: 42621

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00557 FMN_HYDROXY_ACID_DH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNDCHNFQDFRKLAKRRLPGPIFDYIDGAADDEQSYRRNTEAYGECDLIPNVLVGVEN
CCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCHHHHCCCC
VDMSVEVMGQKLDMPIYCAPTALQRLFHHEGERAVARAAAKYGTMFGVSSLATVTVEEIA
CCEEHEEHHHHCCCCEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EITNTPKMFQFYFHKDRGLNDALLERARAANFNVLALTVDTITGGNRERDLRTGFTSPPK
HHHCCHHHHHEEECCCCCCCHHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHCCCCCCCC
LTLGSFMSFATHPAWAWNFLTKEKFDMPHLSGYVSQGTNLAVSVGDYFSTMLDQSMNWND
HHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCH
AEKLCAQWNGQFALKGIMSVEDAKRAIDIGCTGIIVSNHGGRQLDGSRSPFDQLAEICDA
HHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHH
VGDKIDVICEGGIQRGTHVLKALSVGAKACSGGRLYLYALAAAGRAGVERVLGNMRTEIE
CCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHCCHHHHHHHHHHHHHHHH
RDMKLMGVTKLDQLSRDNLRFHHSR
HHHHHHCCHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKLNDCHNFQDFRKLAKRRLPGPIFDYIDGAADDEQSYRRNTEAYGECDLIPNVLVGVEN
CCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCHHHHCCCC
VDMSVEVMGQKLDMPIYCAPTALQRLFHHEGERAVARAAAKYGTMFGVSSLATVTVEEIA
CCEEHEEHHHHCCCCEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EITNTPKMFQFYFHKDRGLNDALLERARAANFNVLALTVDTITGGNRERDLRTGFTSPPK
HHHCCHHHHHEEECCCCCCCHHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHCCCCCCCC
LTLGSFMSFATHPAWAWNFLTKEKFDMPHLSGYVSQGTNLAVSVGDYFSTMLDQSMNWND
HHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCH
AEKLCAQWNGQFALKGIMSVEDAKRAIDIGCTGIIVSNHGGRQLDGSRSPFDQLAEICDA
HHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHH
VGDKIDVICEGGIQRGTHVLKALSVGAKACSGGRLYLYALAAAGRAGVERVLGNMRTEIE
CCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHCCHHHHHHHHHHHHHHHH
RDMKLMGVTKLDQLSRDNLRFHHSR
HHHHHHCCHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA