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The map label for this gene is sdhA [H]

Identifier: 113476095

GI number: 113476095

Start: 3805467

End: 3807194

Strand: Reverse

Name: sdhA [H]

Synonym: Tery_2474

Alternate gene names: 113476095

Gene position: 3807194-3805467 (Counterclockwise)

Preceding gene: 113476096

Following gene: 113476094

Centisome position: 49.12

GC content: 45.43

Gene sequence:

>1728_bases
ATGTTAGAACATGATATAATTATAGTTGGTGGCGGTCTTGCTGGCTGTCGCGCTGCTGTAGAAATAGCTCGAAAAAATCC
TAGTTTAAATGTGGCAGTAGTTGCCAAAACTCACCCTATTCGTTCCCACTCTGTGGCTGCTCAAGGGGGGATAGCGGCGT
CTCTGAGAAATGTAGATACTAAAGATAGCTGGGAAGCTCATGCTTTTGATACTGTTAAGGGTTCGGACTATTTAGCAGAC
CAAGACGCAGTAGAAATTTTAGCGAAGGAGGCACCAGATGTAATTATTGACTTGGAACATCTAGGAGTGTTATTCTCCCG
GTTGCCAGATGGTCGCATCGCTCAACGTGCTTTCGGCGGTCACTCTCACAACCGTACCTGTTATGCTGCGGATAAAACTG
GTCATGCTATTCTTCATGAGTTAGTTAATAACCTTCGCCGTTATGGAGTACATATTTATGAGGAATGGTATGTAATGCGC
CTGATATTGGAAGATACTCAGGCGAAGGGTGTAGTTATGTATCATATTTGGGATGGGGACATAGTTGTACTTCGGGCTAA
GGTGGTAATGTTTGCTACTGGTGGTTATGGTCGGGTATTTAATACTACTTCTAATGATTATGCTTCGACTGGGGATGGTT
TGGCAATGGCGGCTATGGCTGGGTTGCCTCTTCAAGATATGGAGTTTGTGCAGTTTCATCCTACTGGGTTATATCCAGCA
GGGGTTTTAATTTCGGAGGCAGTGCGGGGTGAGGGTGCTTATCTGATCAATAGCGAGGGCGATCGCTTTATGGCAAATTA
TGCTCCTAGTCGTATGGAGTTGGCACCTCGTGATATTACTTCCCGTGCTATTACTTTGGAAATTCGCGCTGGTCGGGGAA
TTAATATGAATGGTAGTGCGGGCGGTCCGTTTATTTATCTTGACCTGCGACACATGGGTCGGGAGAAAATTATGAGTCGG
GTACCTTTTTGTTGGGAAGAGGGTCATCGTCTTTTAGGTATTGATGCGGTGAATGAACCGATGCCAGTACGCCCGACTGC
TCATTATTCTATGGGTGGTATTCCTACTAATACTGATGGTAGAGTTTTCGCGAGTGCGGATACTTTGGTGGATGGGTTAT
TTGCTGCGGGAGAATGTGCTTGTGTTTCGGTACATGGGGCTAACCGTTTGGGAAGTAATTCTTTGTTGGAATGTGTGGTT
TATGGACGACGGACTGGAGCGGCGATCGCTGAGTTTGTTGAGGGTCGGAAGTTGCCTGATGTTGAGGAACAGCGTTATTT
AAGGGAGGCGCGGGCACAAGTTCAGGGGTTGTTAGACCGCTCTGGAGAATATCGGATTAATTTTTTACAGCAGCAGTTTC
AGGATACCATGAGTCAACATTGTGGTGTGTTTCGTTCCCAGGCTATAATGGAGGAGGGGTTTAAAAAATTGGAGCAGTTA
CAGGAACAATATCAGCAGGTTTATTTGGATGATAAGGGTAAGTTGTGGAATACGGAAATTGTTGAGGCGCTGGAGTTGCG
GAGTATTATTGTTGTGGGGGAGACAATTTTAAGTTCGGCTTTGAGTCGCCAGGAAAGTCGGGGGGCTCATAGTCGGGAAG
ATTTTACTAAGCGAAATGATGAGGAGTTTTTACGGCATACTTTGGCTTATTATTCGTTGGCGGGTATTGATATCAGTTAT
CGACCTGTGGCAATAACTATGTTTGAACCAAAGGAACGGAAGTATTGA

Upstream 100 bases:

>100_bases
ACTTGATTTTGGGAAAATATAAAACTAAATTGTTCTTTAGAAGTCTACTATCATAAATGTAAGATAATATAAGTTGAAAA
TTATTTGATATTTACCTATA

Downstream 100 bases:

>100_bases
TCTATTTTATTTCAGATAATTTCAGATAATATTTTCCTGAAATACGATCTGTAGGGAGCAAATTCTATCTGTAGAGGACT
AGTAATATTTGCCTCTATGA

Product: succinate dehydrogenase flavoprotein subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 575; Mature: 575

Protein sequence:

>575_residues
MLEHDIIIVGGGLAGCRAAVEIARKNPSLNVAVVAKTHPIRSHSVAAQGGIAASLRNVDTKDSWEAHAFDTVKGSDYLAD
QDAVEILAKEAPDVIIDLEHLGVLFSRLPDGRIAQRAFGGHSHNRTCYAADKTGHAILHELVNNLRRYGVHIYEEWYVMR
LILEDTQAKGVVMYHIWDGDIVVLRAKVVMFATGGYGRVFNTTSNDYASTGDGLAMAAMAGLPLQDMEFVQFHPTGLYPA
GVLISEAVRGEGAYLINSEGDRFMANYAPSRMELAPRDITSRAITLEIRAGRGINMNGSAGGPFIYLDLRHMGREKIMSR
VPFCWEEGHRLLGIDAVNEPMPVRPTAHYSMGGIPTNTDGRVFASADTLVDGLFAAGECACVSVHGANRLGSNSLLECVV
YGRRTGAAIAEFVEGRKLPDVEEQRYLREARAQVQGLLDRSGEYRINFLQQQFQDTMSQHCGVFRSQAIMEEGFKKLEQL
QEQYQQVYLDDKGKLWNTEIVEALELRSIIVVGETILSSALSRQESRGAHSREDFTKRNDEEFLRHTLAYYSLAGIDISY
RPVAITMFEPKERKY

Sequences:

>Translated_575_residues
MLEHDIIIVGGGLAGCRAAVEIARKNPSLNVAVVAKTHPIRSHSVAAQGGIAASLRNVDTKDSWEAHAFDTVKGSDYLAD
QDAVEILAKEAPDVIIDLEHLGVLFSRLPDGRIAQRAFGGHSHNRTCYAADKTGHAILHELVNNLRRYGVHIYEEWYVMR
LILEDTQAKGVVMYHIWDGDIVVLRAKVVMFATGGYGRVFNTTSNDYASTGDGLAMAAMAGLPLQDMEFVQFHPTGLYPA
GVLISEAVRGEGAYLINSEGDRFMANYAPSRMELAPRDITSRAITLEIRAGRGINMNGSAGGPFIYLDLRHMGREKIMSR
VPFCWEEGHRLLGIDAVNEPMPVRPTAHYSMGGIPTNTDGRVFASADTLVDGLFAAGECACVSVHGANRLGSNSLLECVV
YGRRTGAAIAEFVEGRKLPDVEEQRYLREARAQVQGLLDRSGEYRINFLQQQFQDTMSQHCGVFRSQAIMEEGFKKLEQL
QEQYQQVYLDDKGKLWNTEIVEALELRSIIVVGETILSSALSRQESRGAHSREDFTKRNDEEFLRHTLAYYSLAGIDISY
RPVAITMFEPKERKY
>Mature_575_residues
MLEHDIIIVGGGLAGCRAAVEIARKNPSLNVAVVAKTHPIRSHSVAAQGGIAASLRNVDTKDSWEAHAFDTVKGSDYLAD
QDAVEILAKEAPDVIIDLEHLGVLFSRLPDGRIAQRAFGGHSHNRTCYAADKTGHAILHELVNNLRRYGVHIYEEWYVMR
LILEDTQAKGVVMYHIWDGDIVVLRAKVVMFATGGYGRVFNTTSNDYASTGDGLAMAAMAGLPLQDMEFVQFHPTGLYPA
GVLISEAVRGEGAYLINSEGDRFMANYAPSRMELAPRDITSRAITLEIRAGRGINMNGSAGGPFIYLDLRHMGREKIMSR
VPFCWEEGHRLLGIDAVNEPMPVRPTAHYSMGGIPTNTDGRVFASADTLVDGLFAAGECACVSVHGANRLGSNSLLECVV
YGRRTGAAIAEFVEGRKLPDVEEQRYLREARAQVQGLLDRSGEYRINFLQQQFQDTMSQHCGVFRSQAIMEEGFKKLEQL
QEQYQQVYLDDKGKLWNTEIVEALELRSIIVVGETILSSALSRQESRGAHSREDFTKRNDEEFLRHTLAYYSLAGIDISY
RPVAITMFEPKERKY

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=569, Percent_Identity=43.2337434094903, Blast_Score=461, Evalue=1e-129,
Organism=Escherichia coli, GI1786942, Length=597, Percent_Identity=43.21608040201, Blast_Score=431, Evalue=1e-122,
Organism=Escherichia coli, GI1790597, Length=565, Percent_Identity=39.8230088495575, Blast_Score=398, Evalue=1e-112,
Organism=Escherichia coli, GI1788928, Length=563, Percent_Identity=33.7477797513321, Blast_Score=252, Evalue=5e-68,
Organism=Caenorhabditis elegans, GI17505833, Length=580, Percent_Identity=41.8965517241379, Blast_Score=449, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI17550100, Length=582, Percent_Identity=41.0652920962199, Blast_Score=441, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI71986328, Length=235, Percent_Identity=28.936170212766, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322416, Length=558, Percent_Identity=43.010752688172, Blast_Score=467, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6322701, Length=559, Percent_Identity=42.397137745975, Blast_Score=466, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6322511, Length=486, Percent_Identity=26.1316872427983, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320788, Length=310, Percent_Identity=29.6774193548387, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17137288, Length=576, Percent_Identity=42.1875, Blast_Score=454, Evalue=1e-128,
Organism=Drosophila melanogaster, GI24655642, Length=576, Percent_Identity=42.1875, Blast_Score=454, Evalue=1e-128,
Organism=Drosophila melanogaster, GI24655647, Length=576, Percent_Identity=42.1875, Blast_Score=454, Evalue=1e-128,
Organism=Drosophila melanogaster, GI24663005, Length=578, Percent_Identity=38.4083044982699, Blast_Score=412, Evalue=1e-115,

Paralogues:

None

Copy number: 1900 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1360 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 1100 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR003952
- InterPro:   IPR015939
- InterPro:   IPR004112
- InterPro:   IPR011281
- InterPro:   IPR014006 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF02910 Succ_DH_flav_C [H]

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 63776; Mature: 63776

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00504 FRD_SDH_FAD_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEHDIIIVGGGLAGCRAAVEIARKNPSLNVAVVAKTHPIRSHSVAAQGGIAASLRNVDT
CCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHCCCCHHHHCCCCC
KDSWEAHAFDTVKGSDYLADQDAVEILAKEAPDVIIDLEHLGVLFSRLPDGRIAQRAFGG
CCCCCCCEEECCCCCCCCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCHHHHHHCCC
HSHNRTCYAADKTGHAILHELVNNLRRYGVHIYEEWYVMRLILEDTQAKGVVMYHIWDGD
CCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCC
IVVLRAKVVMFATGGYGRVFNTTSNDYASTGDGLAMAAMAGLPLQDMEFVQFHPTGLYPA
EEEEEEEEEEEEECCCCEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCEEEECCCCCCHH
GVLISEAVRGEGAYLINSEGDRFMANYAPSRMELAPRDITSRAITLEIRAGRGINMNGSA
HHHHHHHHCCCCEEEECCCCCEEEECCCCCCCEECCCCCCCEEEEEEEECCCCCCCCCCC
GGPFIYLDLRHMGREKIMSRVPFCWEEGHRLLGIDAVNEPMPVRPTAHYSMGGIPTNTDG
CCCEEEEEHHHCCHHHHHHHCCCHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
RVFASADTLVDGLFAAGECACVSVHGANRLGSNSLLECVVYGRRTGAAIAEFVEGRKLPD
EEEEEHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCC
VEEQRYLREARAQVQGLLDRSGEYRINFLQQQFQDTMSQHCGVFRSQAIMEEGFKKLEQL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEQYQQVYLDDKGKLWNTEIVEALELRSIIVVGETILSSALSRQESRGAHSREDFTKRND
HHHHHHEEECCCCCCCCHHHHHHHHHHHHEEEHHHHHHHHHHHHHHCCCCCHHHHHCCCH
EEFLRHTLAYYSLAGIDISYRPVAITMFEPKERKY
HHHHHHHHHHHHHCCCCEECCCEEEEEECCCCCCC
>Mature Secondary Structure
MLEHDIIIVGGGLAGCRAAVEIARKNPSLNVAVVAKTHPIRSHSVAAQGGIAASLRNVDT
CCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHCCCCHHHHCCCCC
KDSWEAHAFDTVKGSDYLADQDAVEILAKEAPDVIIDLEHLGVLFSRLPDGRIAQRAFGG
CCCCCCCEEECCCCCCCCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCHHHHHHCCC
HSHNRTCYAADKTGHAILHELVNNLRRYGVHIYEEWYVMRLILEDTQAKGVVMYHIWDGD
CCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCC
IVVLRAKVVMFATGGYGRVFNTTSNDYASTGDGLAMAAMAGLPLQDMEFVQFHPTGLYPA
EEEEEEEEEEEEECCCCEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCEEEECCCCCCHH
GVLISEAVRGEGAYLINSEGDRFMANYAPSRMELAPRDITSRAITLEIRAGRGINMNGSA
HHHHHHHHCCCCEEEECCCCCEEEECCCCCCCEECCCCCCCEEEEEEEECCCCCCCCCCC
GGPFIYLDLRHMGREKIMSRVPFCWEEGHRLLGIDAVNEPMPVRPTAHYSMGGIPTNTDG
CCCEEEEEHHHCCHHHHHHHCCCHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
RVFASADTLVDGLFAAGECACVSVHGANRLGSNSLLECVVYGRRTGAAIAEFVEGRKLPD
EEEEEHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCC
VEEQRYLREARAQVQGLLDRSGEYRINFLQQQFQDTMSQHCGVFRSQAIMEEGFKKLEQL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEQYQQVYLDDKGKLWNTEIVEALELRSIIVVGETILSSALSRQESRGAHSREDFTKRND
HHHHHHEEECCCCCCCCHHHHHHHHHHHHEEEHHHHHHHHHHHHHHCCCCCHHHHHCCCH
EEFLRHTLAYYSLAGIDISYRPVAITMFEPKERKY
HHHHHHHHHHHHHCCCCEECCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA