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The map label for this gene is pkn1 [H]

Identifier: 113475722

GI number: 113475722

Start: 3232566

End: 3233411

Strand: Reverse

Name: pkn1 [H]

Synonym: Tery_2069

Alternate gene names: 113475722

Gene position: 3233411-3232566 (Counterclockwise)

Preceding gene: 113475723

Following gene: 113475721

Centisome position: 41.72

GC content: 43.85

Gene sequence:

>846_bases
ATGGCGACAACACCTATCATAAAACGTCAAAAACAAAAAATTCGAGGTTACAGAGAATATGCTGAGGTGCCTCTGGAAAT
GTTTTTAATTCCTAGTGGCACCTTTACAATGGGCGCACCAAAATCTGAAGAAGGAAGTAGAAATAATGAAAGACCCCAAC
ATAATGTAACTATCTCCGAGTTTCTCATGGGCCGTTATCCTGTTACTCAAGGACAGTGGAGAGCGATCGCCTCCCGAGCA
GACCTGAAAGAAAAACAAGATTTAGACCCAGATCCATCTTACTTTAAAAAACCGTACCAAGATATAGATAGATGGCAAAG
ACCAGTAGAGCGAGTGAATTGGTACGAAGCAGTAGAATTCTGCCAACGACTTTCAAAACTAACTCGAAGAAATTATAGAC
TACCAAGGGAAGCTGAATGGGAATATGCCTGTCGTGCTGGAACTACAACTCCCTTTCATTTTGGAGAAACTATTACTACA
GACTTAGCCAACTATGACGGGACAGGCGATGAAGGTTCTTACGGCAGAGGACTCAAAGGAGAATATCGTCAGGAAACTAC
ACCTGTAGGTTATTTTAAAGTAGCTAATTCTTTTGGGTTGAGCGATATGCACGGGAATGTCTGGGAATGGTGTGCTGATG
AGTGGCATGATAATTATGAAAATGCTCCTACAGATGGCAGTGTTTGGCTAAATGGAAATAAAAAACGTTCACCGCTGCGG
GGCGGTTCCTGGGTCAACATTCCTAATGATTGCCGTTCTGCGATTCGCTACAACTCTGCTGGGCGCGACGTCCACTACGA
CGTTATCGGTTTTCGTGTAGTCTGCGACGGCGGGAGAACTCTTTAA

Upstream 100 bases:

>100_bases
AAGATTATCTTCAAGGTAAAATTAGGTGAGGAAACTTTAAGCAACATAGAGTAAAACTGAAAATTCCTTCAGCCCCCCCA
ACATTTGCAAAAGTAGTTAC

Downstream 100 bases:

>100_bases
CCCTTTTCTCTTTTCCCCTTCAGCCCTTTACCCTGTTTTTCTTTTTCCTGAAATTTCCTGCAGCGACAGTATTATCTATC
TTTGTTGGGTTTGGCGAACT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MATTPIIKRQKQKIRGYREYAEVPLEMFLIPSGTFTMGAPKSEEGSRNNERPQHNVTISEFLMGRYPVTQGQWRAIASRA
DLKEKQDLDPDPSYFKKPYQDIDRWQRPVERVNWYEAVEFCQRLSKLTRRNYRLPREAEWEYACRAGTTTPFHFGETITT
DLANYDGTGDEGSYGRGLKGEYRQETTPVGYFKVANSFGLSDMHGNVWEWCADEWHDNYENAPTDGSVWLNGNKKRSPLR
GGSWVNIPNDCRSAIRYNSAGRDVHYDVIGFRVVCDGGRTL

Sequences:

>Translated_281_residues
MATTPIIKRQKQKIRGYREYAEVPLEMFLIPSGTFTMGAPKSEEGSRNNERPQHNVTISEFLMGRYPVTQGQWRAIASRA
DLKEKQDLDPDPSYFKKPYQDIDRWQRPVERVNWYEAVEFCQRLSKLTRRNYRLPREAEWEYACRAGTTTPFHFGETITT
DLANYDGTGDEGSYGRGLKGEYRQETTPVGYFKVANSFGLSDMHGNVWEWCADEWHDNYENAPTDGSVWLNGNKKRSPLR
GGSWVNIPNDCRSAIRYNSAGRDVHYDVIGFRVVCDGGRTL
>Mature_280_residues
ATTPIIKRQKQKIRGYREYAEVPLEMFLIPSGTFTMGAPKSEEGSRNNERPQHNVTISEFLMGRYPVTQGQWRAIASRAD
LKEKQDLDPDPSYFKKPYQDIDRWQRPVERVNWYEAVEFCQRLSKLTRRNYRLPREAEWEYACRAGTTTPFHFGETITTD
LANYDGTGDEGSYGRGLKGEYRQETTPVGYFKVANSFGLSDMHGNVWEWCADEWHDNYENAPTDGSVWLNGNKKRSPLRG
GSWVNIPNDCRSAIRYNSAGRDVHYDVIGFRVVCDGGRTL

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=286, Percent_Identity=29.020979020979, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI194248087, Length=279, Percent_Identity=26.8817204301075, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI194248088, Length=294, Percent_Identity=25.1700680272109, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI38202250, Length=304, Percent_Identity=26.6447368421053, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI226437577, Length=184, Percent_Identity=30.9782608695652, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI257470977, Length=238, Percent_Identity=27.3109243697479, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI20130397, Length=230, Percent_Identity=27.8260869565217, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 32418; Mature: 32287

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTPIIKRQKQKIRGYREYAEVPLEMFLIPSGTFTMGAPKSEEGSRNNERPQHNVTISE
CCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEECCCCCCCCCCCCCCCCCCCCCHHH
FLMGRYPVTQGQWRAIASRADLKEKQDLDPDPSYFKKPYQDIDRWQRPVERVNWYEAVEF
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CQRLSKLTRRNYRLPREAEWEYACRAGTTTPFHFGETITTDLANYDGTGDEGSYGRGLKG
HHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCC
EYRQETTPVGYFKVANSFGLSDMHGNVWEWCADEWHDNYENAPTDGSVWLNGNKKRSPLR
CHHHCCCCCCCEEEHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCC
GGSWVNIPNDCRSAIRYNSAGRDVHYDVIGFRVVCDGGRTL
CCCEECCCHHHHHHHHCCCCCCEEEEEEEEEEEEECCCCCC
>Mature Secondary Structure 
ATTPIIKRQKQKIRGYREYAEVPLEMFLIPSGTFTMGAPKSEEGSRNNERPQHNVTISE
CCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEECCCCCCCCCCCCCCCCCCCCCHHH
FLMGRYPVTQGQWRAIASRADLKEKQDLDPDPSYFKKPYQDIDRWQRPVERVNWYEAVEF
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CQRLSKLTRRNYRLPREAEWEYACRAGTTTPFHFGETITTDLANYDGTGDEGSYGRGLKG
HHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCC
EYRQETTPVGYFKVANSFGLSDMHGNVWEWCADEWHDNYENAPTDGSVWLNGNKKRSPLR
CHHHCCCCCCCEEEHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCC
GGSWVNIPNDCRSAIRYNSAGRDVHYDVIGFRVVCDGGRTL
CCCEECCCHHHHHHHHCCCCCCEEEEEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]