Click here to switch to the map view.

The map label for this gene is cvrA [H]

Identifier: 113474679

GI number: 113474679

Start: 1359705

End: 1361627

Strand: Reverse

Name: cvrA [H]

Synonym: Tery_0859

Alternate gene names: 113474679

Gene position: 1361627-1359705 (Counterclockwise)

Preceding gene: 113474680

Following gene: 113474678

Centisome position: 17.57

GC content: 38.69

Gene sequence:

>1923_bases
ATGGAAATACCGTTTAATATAACTCTGCTGATTATCCTTACAGTAGCTAGTGGTATAGCTTCCCAAGTTGTGGCTGCCTA
CCTTAAAGTACCTGCAATAGTCTTTTTGCTACTATTTGGTATTTTAGTGGGTAAAGATGGTTTGGGCTTAGTACATCCAA
ACCTATTAGGAAGTGGTCTAGAGGTTATAGTCTCTCTATTTGTAGCCCTAATCTTGTTTGAAGGTGGCCTCAATTTGAAA
CTAAGAGAATTAGGAAGAGTTTCGGGCAGTATCCGCAACTTAGTTACTATAGGGACATTAATCACACTAATTGGTGGAGG
TATGGCTGCTCACTGGTTAGGAGAATTTCCTTGGCCAATTGCATTTTTGTATGCTTCCCTAGTAGTTGTTACAGGGCCAA
CAGTAGTAGGACCATTGCTCAAACAGGTATCAGTAGACCGAAAATTAGCTACTTTGCTTGAGGGAGAAGGAGTTCTCATT
GATCCTATAGGAGCAATTCTAGCCGTATTGGTACTTAATATTGTCTTAAATGAAGGTGCTGCCCCTATAGGATTATTTAG
AGACCTAGTTGTGCGCTTAGGAATGGGCACTATTATTGGTGGGACAGGAGGTTGGCTACTTGGGTTTAGTTTGAAAAGAG
CCAAATTTCTCTCTGAAGAGTTAGCAAACTTAGTGGTTTTAGCTGCTTTGTGGGGGATGTTTGGTCTAGCAGAAGTAGTC
GGCAGTGAATCTGGGTTAATGGCCACAGTAGTAGCCGGGATAGTAGTTGGAGCTGCTGAAATACCAGAATTGCGATTAAT
TAGGCGCTTCAAAGGACAACTGACAATGCTAGGTGTTTCAGTATTGTTTATTCTATTAGCGGCAGACCTATCTTTGGCAA
GTGTTGTTGCCCTAGGTTGGGGAAGTATATTTACAGTTTTGAGCTTGATGTTTCTGGTTCGTCCTCTCAATATATTAATT
TGTACTTGGAATAGTCAGCTTAATTGGCGACAAAAGATGTTTGTTAGTTGGGTTGCTCCTAGAGGAATAGTTTCTGCTTC
AGTTTCTTCTTTGTTTGCTATCTTGTTAACTCAGAATGGTATCAATGGTGGTGACTCTATTAAAGCTTTGGTATTCTTGA
CAATTATGATGACAGTTTTTAGTCAAGGGTTGACAGCAAAATTTGTGGCTCAATTTTTAGGAATTACTTCTAGTGCTGCT
ACTGGTGCTGTTATAGTAGGTTCAAATCCTTTATCTCGATTAATTGGAAAGATATTTAAAGACAGGGGTGAATCAATGGT
ACTAATTGATACAGATGAAGAATCTTGTAAGCAGGCAGAGAAAGAAGGTTTACAAGCATATAAAAGTAGTGCCTTAGATG
TTAATGTCCTAGAAGAAGCTGGCTTAGAATCAGTAGGAACTTTCTTAGCAATGACTAACAATGGGGAAGTAAATTTAGTT
TTGGCTCAAAGAGCAGCAGAGGAGTTTAAGCCACCAAGGGTACTAGCTGTTTATCCAAAAAGTCCCCAGCAGAAAAATCA
TCATAATAAAGAAAAGGTTCAACAAGCATTTACAACTGAATTAAATCTGAAAAGTTGGAATCAATATCTTGATGATCAAG
AGGTGAAGTTAGGTGAGACAGTGCTTAAGGAATTGGGATTTGAGTTTCAAAAGACTCATCTTAAAGCACTGATTCAGTCT
GGGGCATTAATACCACTTTTGGTAGAACGACAAGGAAGTCTTCAAGTATTACCTGCTAGTGAAAATTGGCAACCAAGAGA
CCAGATTATTTATTTGTTACATGACCCAAAACCTAAACTTCTGAAAAGATTATCTGGTTCTCAGCAAACAGCTTTAACTA
TAGAAAGACATCCGGCAGTTGAAGAAGTACCTATTCCTAATGTAGTTCTCGAAAGTAACTCTGACAAAATACCAGCTAAA
TAA

Upstream 100 bases:

>100_bases
AAAATCTAGAAAAACTAACCAGCAAAAATTAAAATAGAAAATTTCAGAGCCAAAATTTGAACCCTGAGAAAAAAGCTGGT
AAGACTTGGAAAAAACGCTT

Downstream 100 bases:

>100_bases
TAATAAAAATTAAAAATATTGGGTATAATATTGGTTTAGGTTGAACATTTAATATTTTAGCTGGGAATAATTGAGAGATA
GGGTTTCCTTAACTGTTGAT

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MEIPFNITLLIILTVASGIASQVVAAYLKVPAIVFLLLFGILVGKDGLGLVHPNLLGSGLEVIVSLFVALILFEGGLNLK
LRELGRVSGSIRNLVTIGTLITLIGGGMAAHWLGEFPWPIAFLYASLVVVTGPTVVGPLLKQVSVDRKLATLLEGEGVLI
DPIGAILAVLVLNIVLNEGAAPIGLFRDLVVRLGMGTIIGGTGGWLLGFSLKRAKFLSEELANLVVLAALWGMFGLAEVV
GSESGLMATVVAGIVVGAAEIPELRLIRRFKGQLTMLGVSVLFILLAADLSLASVVALGWGSIFTVLSLMFLVRPLNILI
CTWNSQLNWRQKMFVSWVAPRGIVSASVSSLFAILLTQNGINGGDSIKALVFLTIMMTVFSQGLTAKFVAQFLGITSSAA
TGAVIVGSNPLSRLIGKIFKDRGESMVLIDTDEESCKQAEKEGLQAYKSSALDVNVLEEAGLESVGTFLAMTNNGEVNLV
LAQRAAEEFKPPRVLAVYPKSPQQKNHHNKEKVQQAFTTELNLKSWNQYLDDQEVKLGETVLKELGFEFQKTHLKALIQS
GALIPLLVERQGSLQVLPASENWQPRDQIIYLLHDPKPKLLKRLSGSQQTALTIERHPAVEEVPIPNVVLESNSDKIPAK

Sequences:

>Translated_640_residues
MEIPFNITLLIILTVASGIASQVVAAYLKVPAIVFLLLFGILVGKDGLGLVHPNLLGSGLEVIVSLFVALILFEGGLNLK
LRELGRVSGSIRNLVTIGTLITLIGGGMAAHWLGEFPWPIAFLYASLVVVTGPTVVGPLLKQVSVDRKLATLLEGEGVLI
DPIGAILAVLVLNIVLNEGAAPIGLFRDLVVRLGMGTIIGGTGGWLLGFSLKRAKFLSEELANLVVLAALWGMFGLAEVV
GSESGLMATVVAGIVVGAAEIPELRLIRRFKGQLTMLGVSVLFILLAADLSLASVVALGWGSIFTVLSLMFLVRPLNILI
CTWNSQLNWRQKMFVSWVAPRGIVSASVSSLFAILLTQNGINGGDSIKALVFLTIMMTVFSQGLTAKFVAQFLGITSSAA
TGAVIVGSNPLSRLIGKIFKDRGESMVLIDTDEESCKQAEKEGLQAYKSSALDVNVLEEAGLESVGTFLAMTNNGEVNLV
LAQRAAEEFKPPRVLAVYPKSPQQKNHHNKEKVQQAFTTELNLKSWNQYLDDQEVKLGETVLKELGFEFQKTHLKALIQS
GALIPLLVERQGSLQVLPASENWQPRDQIIYLLHDPKPKLLKRLSGSQQTALTIERHPAVEEVPIPNVVLESNSDKIPAK
>Mature_640_residues
MEIPFNITLLIILTVASGIASQVVAAYLKVPAIVFLLLFGILVGKDGLGLVHPNLLGSGLEVIVSLFVALILFEGGLNLK
LRELGRVSGSIRNLVTIGTLITLIGGGMAAHWLGEFPWPIAFLYASLVVVTGPTVVGPLLKQVSVDRKLATLLEGEGVLI
DPIGAILAVLVLNIVLNEGAAPIGLFRDLVVRLGMGTIIGGTGGWLLGFSLKRAKFLSEELANLVVLAALWGMFGLAEVV
GSESGLMATVVAGIVVGAAEIPELRLIRRFKGQLTMLGVSVLFILLAADLSLASVVALGWGSIFTVLSLMFLVRPLNILI
CTWNSQLNWRQKMFVSWVAPRGIVSASVSSLFAILLTQNGINGGDSIKALVFLTIMMTVFSQGLTAKFVAQFLGITSSAA
TGAVIVGSNPLSRLIGKIFKDRGESMVLIDTDEESCKQAEKEGLQAYKSSALDVNVLEEAGLESVGTFLAMTNNGEVNLV
LAQRAAEEFKPPRVLAVYPKSPQQKNHHNKEKVQQAFTTELNLKSWNQYLDDQEVKLGETVLKELGFEFQKTHLKALIQS
GALIPLLVERQGSLQVLPASENWQPRDQIIYLLHDPKPKLLKRLSGSQQTALTIERHPAVEEVPIPNVVLESNSDKIPAK

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018421
- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 68799; Mature: 68799

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIPFNITLLIILTVASGIASQVVAAYLKVPAIVFLLLFGILVGKDGLGLVHPNLLGSGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHCCHH
EVIVSLFVALILFEGGLNLKLRELGRVSGSIRNLVTIGTLITLIGGGMAAHWLGEFPWPI
HHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHH
AFLYASLVVVTGPTVVGPLLKQVSVDRKLATLLEGEGVLIDPIGAILAVLVLNIVLNEGA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCCC
APIGLFRDLVVRLGMGTIIGGTGGWLLGFSLKRAKFLSEELANLVVLAALWGMFGLAEVV
CHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSESGLMATVVAGIVVGAAEIPELRLIRRFKGQLTMLGVSVLFILLAADLSLASVVALGW
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSIFTVLSLMFLVRPLNILICTWNSQLNWRQKMFVSWVAPRGIVSASVSSLFAILLTQNG
HHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
INGGDSIKALVFLTIMMTVFSQGLTAKFVAQFLGITSSAATGAVIVGSNPLSRLIGKIFK
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHH
DRGESMVLIDTDEESCKQAEKEGLQAYKSSALDVNVLEEAGLESVGTFLAMTNNGEVNLV
CCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHEEEEECCCCEEEE
LAQRAAEEFKPPRVLAVYPKSPQQKNHHNKEKVQQAFTTELNLKSWNQYLDDQEVKLGET
EEHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHH
VLKELGFEFQKTHLKALIQSGALIPLLVERQGSLQVLPASENWQPRDQIIYLLHDPKPKL
HHHHHCCHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCCCCHHHEEEEEECCCHHH
LKRLSGSQQTALTIERHPAVEEVPIPNVVLESNSDKIPAK
HHHHCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCC
>Mature Secondary Structure
MEIPFNITLLIILTVASGIASQVVAAYLKVPAIVFLLLFGILVGKDGLGLVHPNLLGSGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHCCHH
EVIVSLFVALILFEGGLNLKLRELGRVSGSIRNLVTIGTLITLIGGGMAAHWLGEFPWPI
HHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHH
AFLYASLVVVTGPTVVGPLLKQVSVDRKLATLLEGEGVLIDPIGAILAVLVLNIVLNEGA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCCC
APIGLFRDLVVRLGMGTIIGGTGGWLLGFSLKRAKFLSEELANLVVLAALWGMFGLAEVV
CHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSESGLMATVVAGIVVGAAEIPELRLIRRFKGQLTMLGVSVLFILLAADLSLASVVALGW
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSIFTVLSLMFLVRPLNILICTWNSQLNWRQKMFVSWVAPRGIVSASVSSLFAILLTQNG
HHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
INGGDSIKALVFLTIMMTVFSQGLTAKFVAQFLGITSSAATGAVIVGSNPLSRLIGKIFK
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHH
DRGESMVLIDTDEESCKQAEKEGLQAYKSSALDVNVLEEAGLESVGTFLAMTNNGEVNLV
CCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHEEEEECCCCEEEE
LAQRAAEEFKPPRVLAVYPKSPQQKNHHNKEKVQQAFTTELNLKSWNQYLDDQEVKLGET
EEHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHH
VLKELGFEFQKTHLKALIQSGALIPLLVERQGSLQVLPASENWQPRDQIIYLLHDPKPKL
HHHHHCCHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCCCCHHHEEEEEECCCHHH
LKRLSGSQQTALTIERHPAVEEVPIPNVVLESNSDKIPAK
HHHHCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA