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The map label for this gene is dnaX [H]

Identifier: 113474658

GI number: 113474658

Start: 1320189

End: 1322276

Strand: Reverse

Name: dnaX [H]

Synonym: Tery_0832

Alternate gene names: 113474658

Gene position: 1322276-1320189 (Counterclockwise)

Preceding gene: 113474662

Following gene: 113474657

Centisome position: 17.06

GC content: 36.45

Gene sequence:

>2088_bases
GTGGCTTACGAACCTCTTCATCATAAATATCGTCCTCAAACCTTTGCAGACTTAGTGGGTCAAGATGTGATTGCCCAAAC
TCTCACTAATGCCATCCATACCAAACGCATCGCCCCAGCATATCTATTTACAGGACCTAGAGGCACAGGCAAAACCTCTA
GTGCTCGGGTTTTGGCCAAATCTCTCAATTGTCTGTCCTATGACCACCCTACACCGAGTCCCTGTGGCACTTGTAATGTT
TGTGTAGGAATTACAAAAGGGTCAACACTGGACGTTATAGAAATTGATGCTGCTAGCAATACTGGTGTGGACAACATTAG
GGAATTAATTGAAAGATCCCAGTTTGCACCTGTGCAGTGTCGCTATAAAGTATATGTGATAGATGAAGTCCACATGTTGT
CTGTGTCTGCCTTCAATGCTTTACTGAAAACTTTGGAGGAACCGCCAAAGGGAGTAGTATTTATCCTGGCTACTACAGAT
CCACAGAGAGTCTTAGCAACTATTATTTCCCGTTGCCAACGTTTTGACTTTCGCCGAATTCCTCTTGAAGCAATGGTCAA
GCATTTACATCATATTGCTATTGAGGAAAAAATTGATATTACAACTGAAGCGATACAGATGATAGCTCAAATTGCTCAGG
GTGGGTTAAGAGATGCAGAGAGTTTGCTAGATCAGTTGAGTTTGTTGGCAGGAGAAATTACGGTTGAACGAGTTTGGGAT
CTGGTGGGGGCGGTGCCGGAACGAGATTTAATGGTACTGGTAGAAGCGATCGCTGCGGATAATTCCATAAAAGTATTGAA
GTGCACTCGCCAAATTATGGATCGGGGTAAGGAACCAATTATTGTATTGCAAAATTTGGCAGGGTTTTACCGAGATTTAT
TGATAGCAAAAACAGCACCAACAAGTAAAAATTTAGTAGCCTTGACAAAACCTACTTGGGAAAAGCTTTGTCAATTTTCT
CAAGACTGGGATATTGGAACTATTTTAGCTGGTCAAAAGCATTTACAAACATCGGAAGTACAAATTAAAAATACTACTCA
ACCTCGTTTATGGTTGGAGGTAACTTTATTAGGGTTATTACCTTCTGCATTACCGAAATTTAACCAGTTGGAAAAACAAG
AAACTAGAGATATAAGTCAGAATGTTTCTGTTAAAAATACTTCCAAAAATTTATCACAACCCCTGACAAAAAAACCGATT
TCTGAAAAACCAAAACAGCAAATCTCAGAACCAAAAGAAGTTTCTAAAGAAGTTCCTATTGCTCCTAAAAGTGAAGATTT
TTTTACTTCTTCAACTAATGATACAGCAAAAAAATCTTCGTCAGATTCATTAGAAACTGACAAGATTAAGAATGAATCAG
AATTACAGAATATTTGGGAAAAAGTTCTAGCAGAAGTTAAACCACACAGTACACAAGCTTTATTAAGTCAACAAGTCATA
TTATTAGGGTATAATAATGAACTGGCGCGTATTGGTATTAGCTCTAAGAATTTAGAGAAAATGGTTATTCATAAAATTCC
TAATATTGAAGCTGCGTTTGAGAAAATTTTTCAGACTTCGGTAAAAGTAAAAGTAGAGGTAAAAAATTCTCAACAAAAAC
AGCATAGTTTTCGTGAAAATATTTATCCGAATCATAGTCCAAGAGAAAGGCTAAACAGTAATAATAAGCTAAGGCAAGAA
AACTCTAATTATGATGATAAAATTGCCGAAGATGAACCAGAAAATTTCCCAGTTTCCTATCCGAGCAACTCCCAGAAAGA
AAAGAAAACTACCCCAAATTTTTCTCTGCCTAATTCACCTTTGAATGATTTGGTAGAAAAGGAAAAATATCCTGAAGGAA
AAAGAGATTCTGTGGCGATCGCTACTCGTCGGATAGTTAATTTTTTTAAGGGAGAAATAGTAGATATAAAATCAATTAAA
TTGCCAGATAAAATAGATCAAGCAGATAAAACTGATTTACCTGCAACATCTGAGTCTTCTGATTTATCTATTGATGTTCA
GAGTCAAAAATCTAAAAATAGCCATGTTGGTATAGATGAACCAGAAGAAAATGAAGGGGATAATTTTAATGATGATATTA
TATTTTAA

Upstream 100 bases:

>100_bases
AAGAAACATAAAAGTCTTTCTATTGAATAAAATCTAGTAAAGTTGTATTGGTTATAACCTTATCTAAACTAAATATTCAA
AATAATTCTTATTCCTAATT

Downstream 100 bases:

>100_bases
TCTGATTATCCTCAATTAAATTAAGACTCAGTTTATCAGTGGAGAATTTTTTGTTTTCTAGCCCATATTCAGCAGGTCAA
TTTGTAATTGAAAAAAAAGT

Product: DNA polymerase III s gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 695; Mature: 694

Protein sequence:

>695_residues
MAYEPLHHKYRPQTFADLVGQDVIAQTLTNAIHTKRIAPAYLFTGPRGTGKTSSARVLAKSLNCLSYDHPTPSPCGTCNV
CVGITKGSTLDVIEIDAASNTGVDNIRELIERSQFAPVQCRYKVYVIDEVHMLSVSAFNALLKTLEEPPKGVVFILATTD
PQRVLATIISRCQRFDFRRIPLEAMVKHLHHIAIEEKIDITTEAIQMIAQIAQGGLRDAESLLDQLSLLAGEITVERVWD
LVGAVPERDLMVLVEAIAADNSIKVLKCTRQIMDRGKEPIIVLQNLAGFYRDLLIAKTAPTSKNLVALTKPTWEKLCQFS
QDWDIGTILAGQKHLQTSEVQIKNTTQPRLWLEVTLLGLLPSALPKFNQLEKQETRDISQNVSVKNTSKNLSQPLTKKPI
SEKPKQQISEPKEVSKEVPIAPKSEDFFTSSTNDTAKKSSSDSLETDKIKNESELQNIWEKVLAEVKPHSTQALLSQQVI
LLGYNNELARIGISSKNLEKMVIHKIPNIEAAFEKIFQTSVKVKVEVKNSQQKQHSFRENIYPNHSPRERLNSNNKLRQE
NSNYDDKIAEDEPENFPVSYPSNSQKEKKTTPNFSLPNSPLNDLVEKEKYPEGKRDSVAIATRRIVNFFKGEIVDIKSIK
LPDKIDQADKTDLPATSESSDLSIDVQSQKSKNSHVGIDEPEENEGDNFNDDIIF

Sequences:

>Translated_695_residues
MAYEPLHHKYRPQTFADLVGQDVIAQTLTNAIHTKRIAPAYLFTGPRGTGKTSSARVLAKSLNCLSYDHPTPSPCGTCNV
CVGITKGSTLDVIEIDAASNTGVDNIRELIERSQFAPVQCRYKVYVIDEVHMLSVSAFNALLKTLEEPPKGVVFILATTD
PQRVLATIISRCQRFDFRRIPLEAMVKHLHHIAIEEKIDITTEAIQMIAQIAQGGLRDAESLLDQLSLLAGEITVERVWD
LVGAVPERDLMVLVEAIAADNSIKVLKCTRQIMDRGKEPIIVLQNLAGFYRDLLIAKTAPTSKNLVALTKPTWEKLCQFS
QDWDIGTILAGQKHLQTSEVQIKNTTQPRLWLEVTLLGLLPSALPKFNQLEKQETRDISQNVSVKNTSKNLSQPLTKKPI
SEKPKQQISEPKEVSKEVPIAPKSEDFFTSSTNDTAKKSSSDSLETDKIKNESELQNIWEKVLAEVKPHSTQALLSQQVI
LLGYNNELARIGISSKNLEKMVIHKIPNIEAAFEKIFQTSVKVKVEVKNSQQKQHSFRENIYPNHSPRERLNSNNKLRQE
NSNYDDKIAEDEPENFPVSYPSNSQKEKKTTPNFSLPNSPLNDLVEKEKYPEGKRDSVAIATRRIVNFFKGEIVDIKSIK
LPDKIDQADKTDLPATSESSDLSIDVQSQKSKNSHVGIDEPEENEGDNFNDDIIF
>Mature_694_residues
AYEPLHHKYRPQTFADLVGQDVIAQTLTNAIHTKRIAPAYLFTGPRGTGKTSSARVLAKSLNCLSYDHPTPSPCGTCNVC
VGITKGSTLDVIEIDAASNTGVDNIRELIERSQFAPVQCRYKVYVIDEVHMLSVSAFNALLKTLEEPPKGVVFILATTDP
QRVLATIISRCQRFDFRRIPLEAMVKHLHHIAIEEKIDITTEAIQMIAQIAQGGLRDAESLLDQLSLLAGEITVERVWDL
VGAVPERDLMVLVEAIAADNSIKVLKCTRQIMDRGKEPIIVLQNLAGFYRDLLIAKTAPTSKNLVALTKPTWEKLCQFSQ
DWDIGTILAGQKHLQTSEVQIKNTTQPRLWLEVTLLGLLPSALPKFNQLEKQETRDISQNVSVKNTSKNLSQPLTKKPIS
EKPKQQISEPKEVSKEVPIAPKSEDFFTSSTNDTAKKSSSDSLETDKIKNESELQNIWEKVLAEVKPHSTQALLSQQVIL
LGYNNELARIGISSKNLEKMVIHKIPNIEAAFEKIFQTSVKVKVEVKNSQQKQHSFRENIYPNHSPRERLNSNNKLRQEN
SNYDDKIAEDEPENFPVSYPSNSQKEKKTTPNFSLPNSPLNDLVEKEKYPEGKRDSVAIATRRIVNFFKGEIVDIKSIKL
PDKIDQADKTDLPATSESSDLSIDVQSQKSKNSHVGIDEPEENEGDNFNDDIIF

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=243, Percent_Identity=30.4526748971193, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI194306571, Length=239, Percent_Identity=30.5439330543933, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI194306567, Length=239, Percent_Identity=30.5439330543933, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI4506491, Length=322, Percent_Identity=24.223602484472, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI31881687, Length=322, Percent_Identity=24.223602484472, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI194306569, Length=156, Percent_Identity=28.8461538461538, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI31563534, Length=243, Percent_Identity=24.6913580246914, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1786676, Length=366, Percent_Identity=40.9836065573771, Blast_Score=258, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI17554730, Length=226, Percent_Identity=25.6637168141593, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71986063, Length=307, Percent_Identity=24.1042345276873, Blast_Score=83, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6324039, Length=266, Percent_Identity=24.4360902255639, Blast_Score=95, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6322528, Length=313, Percent_Identity=24.6006389776358, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6324478, Length=243, Percent_Identity=24.2798353909465, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17647857, Length=289, Percent_Identity=24.9134948096886, Blast_Score=89, Evalue=2e-17,
Organism=Drosophila melanogaster, GI18859927, Length=282, Percent_Identity=25.177304964539, Blast_Score=85, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 77871; Mature: 77740

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYEPLHHKYRPQTFADLVGQDVIAQTLTNAIHTKRIAPAYLFTGPRGTGKTSSARVLAK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHH
SLNCLSYDHPTPSPCGTCNVCVGITKGSTLDVIEIDAASNTGVDNIRELIERSQFAPVQC
HHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEE
RYKVYVIDEVHMLSVSAFNALLKTLEEPPKGVVFILATTDPQRVLATIISRCQRFDFRRI
EEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCC
PLEAMVKHLHHIAIEEKIDITTEAIQMIAQIAQGGLRDAESLLDQLSLLAGEITVERVWD
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LVGAVPERDLMVLVEAIAADNSIKVLKCTRQIMDRGKEPIIVLQNLAGFYRDLLIAKTAP
HHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCC
TSKNLVALTKPTWEKLCQFSQDWDIGTILAGQKHLQTSEVQIKNTTQPRLWLEVTLLGLL
CCCCEEEEECCHHHHHHCCCCCCCCEEEECCCHHCCCCCEEEECCCCCEEEHHHHHHHHH
PSALPKFNQLEKQETRDISQNVSVKNTSKNLSQPLTKKPISEKPKQQISEPKEVSKEVPI
HHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHCCCCCCCHHHHCCCHHHHHHCCCC
APKSEDFFTSSTNDTAKKSSSDSLETDKIKNESELQNIWEKVLAEVKPHSTQALLSQQVI
CCCCCCCCCCCCCCHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCEE
LLGYNNELARIGISSKNLEKMVIHKIPNIEAAFEKIFQTSVKVKVEVKNSQQKQHSFREN
EEECCCCEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHC
IYPNHSPRERLNSNNKLRQENSNYDDKIAEDEPENFPVSYPSNSQKEKKTTPNFSLPNSP
CCCCCCHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCC
LNDLVEKEKYPEGKRDSVAIATRRIVNFFKGEIVDIKSIKLPDKIDQADKTDLPATSESS
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHCCCCCCCCCCCCCCC
DLSIDVQSQKSKNSHVGIDEPEENEGDNFNDDIIF
CEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AYEPLHHKYRPQTFADLVGQDVIAQTLTNAIHTKRIAPAYLFTGPRGTGKTSSARVLAK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHH
SLNCLSYDHPTPSPCGTCNVCVGITKGSTLDVIEIDAASNTGVDNIRELIERSQFAPVQC
HHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEE
RYKVYVIDEVHMLSVSAFNALLKTLEEPPKGVVFILATTDPQRVLATIISRCQRFDFRRI
EEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCC
PLEAMVKHLHHIAIEEKIDITTEAIQMIAQIAQGGLRDAESLLDQLSLLAGEITVERVWD
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LVGAVPERDLMVLVEAIAADNSIKVLKCTRQIMDRGKEPIIVLQNLAGFYRDLLIAKTAP
HHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCC
TSKNLVALTKPTWEKLCQFSQDWDIGTILAGQKHLQTSEVQIKNTTQPRLWLEVTLLGLL
CCCCEEEEECCHHHHHHCCCCCCCCEEEECCCHHCCCCCEEEECCCCCEEEHHHHHHHHH
PSALPKFNQLEKQETRDISQNVSVKNTSKNLSQPLTKKPISEKPKQQISEPKEVSKEVPI
HHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHCCCCCCCHHHHCCCHHHHHHCCCC
APKSEDFFTSSTNDTAKKSSSDSLETDKIKNESELQNIWEKVLAEVKPHSTQALLSQQVI
CCCCCCCCCCCCCCHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCEE
LLGYNNELARIGISSKNLEKMVIHKIPNIEAAFEKIFQTSVKVKVEVKNSQQKQHSFREN
EEECCCCEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHC
IYPNHSPRERLNSNNKLRQENSNYDDKIAEDEPENFPVSYPSNSQKEKKTTPNFSLPNSP
CCCCCCHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCC
LNDLVEKEKYPEGKRDSVAIATRRIVNFFKGEIVDIKSIKLPDKIDQADKTDLPATSESS
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHCCCCCCCCCCCCCCC
DLSIDVQSQKSKNSHVGIDEPEENEGDNFNDDIIF
CEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]