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The map label for this gene is tig

Identifier: 113474442

GI number: 113474442

Start: 940019

End: 941476

Strand: Reverse

Name: tig

Synonym: Tery_0586

Alternate gene names: 113474442

Gene position: 941476-940019 (Counterclockwise)

Preceding gene: 113474446

Following gene: 113474441

Centisome position: 12.15

GC content: 37.38

Gene sequence:

>1458_bases
ATGAAAGTTACTCAGGAAAAACTACCAGCTAGTCAAATAAGTCTAGAAATTGAGATTTCACCAGAAATGTCCAAAAATGC
TTATGAGCAGATAATTAAGAAATATATCCGTTCGGCCAATATTCCTGGTTTCAGAAAAGGTAAAGTACCTAGAAACATTT
TGATCCAAAGACTAGGAAAAAATTATATTAAGGCCATGGCCTTAGATGACTTAATCAATAATTGCTTAGAAAAAGCAAGG
GAACAAGAAAGCATCAAAGCAATAGGCCAATTTGAACTAAAAACCGAGTTTGAAGAGTTAGTAAAAGATTTTGAACCAGG
AAAAGAAATGGCTTTCTCGGCCAAGGTAGATGTAGAGCCAGAGGCCAAGGTTGAGGATTATAAGGGATTCTTGGTTCAGG
CGGAAGAAGCTAAGTATGACTCAGCCCTTGTGGATGAATTTCTTGAAGAACGTCGCTCTCGAATGGGAACATTAATTCCT
ATAGAAGGAAGAGCTGCTGAGATGGGAGATGTGGCCATAGTGGATTTTGTAGGTATAATTCCATCAGAGACGGAAGGAGA
AGAAGCACAAGAAGTGCCGGGGGGTAAGGCTCAAGATTTCCAAATGGATTTAAAAGAAGGACAATTTATTCCTGGCTTTA
TTGAGGGAATAGTGGGGATGAAGTTACAGGAAACAAAGGAAATTTCTGCACAGTTTCCTTCGGAATATAGTGAGGCAAAT
TTAGCCGGTAAGCCAGTGGTATTTACTGTGACTCTTAAAGAACTCAAAGAAAAGGAATTACCAGAATTAGATGATGATTT
AGCTCAAGAGATTAGTGAGTTTGAAACAATAGACAAATTACGAGAGTTTTTGGAGCAAAAATTTACTAAAGAAAAAGAGG
AAAAAACAAAACAAAATAAGGAAAAGGCTATTATAGACGAGCTGGTGACTCATCTAGAAGTAGAAATTCCAGAAACTTTA
ATTAAAAATGAAGTTCAGCAAATGTTAGCCCAAAGTGCGATGGATTTGAGTCAGTATGGAATAGATGTTAAAGAATTCTT
CAGCAGTGAGAAATTGCCGGAAATGCAAGAGCGTACACGACCTGAAGCAATTGAGCGATTAAAAAGGGATTTGGTCATAG
CTACAGTGGCAAAAAGAGAGTCTATTACCGTGGACGAAGAAGAAATAAAAGCAGAGTCACAGAAAGTAGTGAAGCAGCTC
AAAGAAAAAGATTTTGATTCAGATAGGTTAAGACAAGTAGTTACTCAAGAATTGTTGAAAGAAAAAACTATCAAATGGCT
AGAAGCAAATGGCACTGTGGAATTAGTCCCTGAAGGAACTTTGCATACAGAATCACAAACACCTCAAACTACAGAAATCT
TAGAAACAGAGGTAGAGTCAGAAATACCTCAAGCTAGTGAAACTATTGTAGAAGTAAAGGCAGAGGAAGTAGCTACTGTA
GAAAATTCTCAGGAATAG

Upstream 100 bases:

>100_bases
CAAATAAATAAAGGGAAATACTAAACTACCTAAGCAATAGATATTCATATAGCTTAAAAAAAATCATAACCTATAGTACT
TACTAAAATTATAAAAGCCG

Downstream 100 bases:

>100_bases
GAGGCAGAAGATTGACTGATATACCCACGGTTATTCCCGCCGCGGGGTTAGATATAATGGGAGTGAAATCCCTGTGGGGG
TTGATGTTTCAGATATGCTA

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MKVTQEKLPASQISLEIEISPEMSKNAYEQIIKKYIRSANIPGFRKGKVPRNILIQRLGKNYIKAMALDDLINNCLEKAR
EQESIKAIGQFELKTEFEELVKDFEPGKEMAFSAKVDVEPEAKVEDYKGFLVQAEEAKYDSALVDEFLEERRSRMGTLIP
IEGRAAEMGDVAIVDFVGIIPSETEGEEAQEVPGGKAQDFQMDLKEGQFIPGFIEGIVGMKLQETKEISAQFPSEYSEAN
LAGKPVVFTVTLKELKEKELPELDDDLAQEISEFETIDKLREFLEQKFTKEKEEKTKQNKEKAIIDELVTHLEVEIPETL
IKNEVQQMLAQSAMDLSQYGIDVKEFFSSEKLPEMQERTRPEAIERLKRDLVIATVAKRESITVDEEEIKAESQKVVKQL
KEKDFDSDRLRQVVTQELLKEKTIKWLEANGTVELVPEGTLHTESQTPQTTEILETEVESEIPQASETIVEVKAEEVATV
ENSQE

Sequences:

>Translated_485_residues
MKVTQEKLPASQISLEIEISPEMSKNAYEQIIKKYIRSANIPGFRKGKVPRNILIQRLGKNYIKAMALDDLINNCLEKAR
EQESIKAIGQFELKTEFEELVKDFEPGKEMAFSAKVDVEPEAKVEDYKGFLVQAEEAKYDSALVDEFLEERRSRMGTLIP
IEGRAAEMGDVAIVDFVGIIPSETEGEEAQEVPGGKAQDFQMDLKEGQFIPGFIEGIVGMKLQETKEISAQFPSEYSEAN
LAGKPVVFTVTLKELKEKELPELDDDLAQEISEFETIDKLREFLEQKFTKEKEEKTKQNKEKAIIDELVTHLEVEIPETL
IKNEVQQMLAQSAMDLSQYGIDVKEFFSSEKLPEMQERTRPEAIERLKRDLVIATVAKRESITVDEEEIKAESQKVVKQL
KEKDFDSDRLRQVVTQELLKEKTIKWLEANGTVELVPEGTLHTESQTPQTTEILETEVESEIPQASETIVEVKAEEVATV
ENSQE
>Mature_485_residues
MKVTQEKLPASQISLEIEISPEMSKNAYEQIIKKYIRSANIPGFRKGKVPRNILIQRLGKNYIKAMALDDLINNCLEKAR
EQESIKAIGQFELKTEFEELVKDFEPGKEMAFSAKVDVEPEAKVEDYKGFLVQAEEAKYDSALVDEFLEERRSRMGTLIP
IEGRAAEMGDVAIVDFVGIIPSETEGEEAQEVPGGKAQDFQMDLKEGQFIPGFIEGIVGMKLQETKEISAQFPSEYSEAN
LAGKPVVFTVTLKELKEKELPELDDDLAQEISEFETIDKLREFLEQKFTKEKEEKTKQNKEKAIIDELVTHLEVEIPETL
IKNEVQQMLAQSAMDLSQYGIDVKEFFSSEKLPEMQERTRPEAIERLKRDLVIATVAKRESITVDEEEIKAESQKVVKQL
KEKDFDSDRLRQVVTQELLKEKTIKWLEANGTVELVPEGTLHTESQTPQTTEILETEVESEIPQASETIVEVKAEEVATV
ENSQE

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=392, Percent_Identity=27.5510204081633, Blast_Score=124, Evalue=1e-29,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_TRIEI (Q118P4)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_720503.1
- ProteinModelPortal:   Q118P4
- STRING:   Q118P4
- GeneID:   4244612
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_0586
- NMPDR:   fig|203124.1.peg.3577
- eggNOG:   COG0544
- HOGENOM:   HBG635105
- OMA:   RFIPGFE
- ProtClustDB:   PRK01490
- BioCyc:   TERY203124:TERY_0586-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 55142; Mature: 55142

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTQEKLPASQISLEIEISPEMSKNAYEQIIKKYIRSANIPGFRKGKVPRNILIQRLGK
CCCCHHHCCHHHEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
NYIKAMALDDLINNCLEKAREQESIKAIGQFELKTEFEELVKDFEPGKEMAFSAKVDVEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCC
EAKVEDYKGFLVQAEEAKYDSALVDEFLEERRSRMGTLIPIEGRAAEMGDVAIVDFVGII
CCCHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHCC
PSETEGEEAQEVPGGKAQDFQMDLKEGQFIPGFIEGIVGMKLQETKEISAQFPSEYSEAN
CCCCCCCHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHCCCHHHCCC
LAGKPVVFTVTLKELKEKELPELDDDLAQEISEFETIDKLREFLEQKFTKEKEEKTKQNK
CCCCCEEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKAIIDELVTHLEVEIPETLIKNEVQQMLAQSAMDLSQYGIDVKEFFSSEKLPEMQERTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHCC
PEAIERLKRDLVIATVAKRESITVDEEEIKAESQKVVKQLKEKDFDSDRLRQVVTQELLK
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
EKTIKWLEANGTVELVPEGTLHTESQTPQTTEILETEVESEIPQASETIVEVKAEEVATV
HHHHHHEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ENSQE
CCCCC
>Mature Secondary Structure
MKVTQEKLPASQISLEIEISPEMSKNAYEQIIKKYIRSANIPGFRKGKVPRNILIQRLGK
CCCCHHHCCHHHEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
NYIKAMALDDLINNCLEKAREQESIKAIGQFELKTEFEELVKDFEPGKEMAFSAKVDVEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCC
EAKVEDYKGFLVQAEEAKYDSALVDEFLEERRSRMGTLIPIEGRAAEMGDVAIVDFVGII
CCCHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHCC
PSETEGEEAQEVPGGKAQDFQMDLKEGQFIPGFIEGIVGMKLQETKEISAQFPSEYSEAN
CCCCCCCHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHCCCHHHCCC
LAGKPVVFTVTLKELKEKELPELDDDLAQEISEFETIDKLREFLEQKFTKEKEEKTKQNK
CCCCCEEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKAIIDELVTHLEVEIPETLIKNEVQQMLAQSAMDLSQYGIDVKEFFSSEKLPEMQERTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHCC
PEAIERLKRDLVIATVAKRESITVDEEEIKAESQKVVKQLKEKDFDSDRLRQVVTQELLK
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
EKTIKWLEANGTVELVPEGTLHTESQTPQTTEILETEVESEIPQASETIVEVKAEEVATV
HHHHHHEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ENSQE
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA