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The map label for this gene is hisS [H]

Identifier: 113474434

GI number: 113474434

Start: 927461

End: 929014

Strand: Direct

Name: hisS [H]

Synonym: Tery_0577

Alternate gene names: 113474434

Gene position: 927461-929014 (Clockwise)

Preceding gene: 113474432

Following gene: 113474435

Centisome position: 11.97

GC content: 34.43

Gene sequence:

>1554_bases
ATGCAAACTATCAAAGTAGAAAGAGTCACAGGAGTTAACGACATTCTCCCAAGTACCTACCAGATAGATCAACAAATCAA
AAGTATACTGAGTAGCAATTTTGAGTCCTATGGATATCGACCCATAGATGTACCACTCATAGAATATACCGAACTCTATC
TAAAAAAATCTGGTGAGGATATTATTTCTCGTCTCTACGACTTCATTTACCGCAACCGTCGCCTCTGTCTAAGACCAGAA
TTTACAGCTTCAGTGGTCCGTGCTTATTTAGACAATTTACAAGAACTACCCCTGCCAGTGCGACTTTATTATATGGGGCC
AGTATTTCGTTATGAACAGCCCCAGAAAGAAAAATATGGACAGTTTACTCAAATGGGAATAGAGTTAATAGGTGCCACAG
GAGCGATCGCTGATGGGGAAATTATTTCTATGGCCTGTCAAGGTTTAGATCGTCTAGGTTTAACTGAATATCAAACATTT
ATCGGCCACGTTGGAGTCCTCAATAATTTTCTTGACCATCTTCAGCTAGACACTCGTCTTCGTAGTTTTCTACTTACTCA
GATGGAAACTCTAAGAATAGAAGGTAAAGAGATAGTAGAAAGTCGACTTTCTGAAATCTATCCTGCTTTTAAAAAAAATA
ATTTTTTGGCAGAACAACTAGATACAAATACGACAACAAAAAAAATCACAGATATCCTACAAAATTTAGAAGAAAATGAG
GCAAGAACAGCAATTTTTAAGTTGCTGGAAAGTATGAATATAGAACTTACAAGTACTCGTACACCAGAAGAAATAGTTGA
CCGTTTGTTAATTAAAATTAAACATCAAGATCAAACTAAAGAGCTAAATCAAGCATTAGAGTTTATGACAGAATTGAGTC
AACTCAAAGGAGAGCCTCAAGCCATATTCAAAGAAATAAAAAAACTACTTTCGGCTTATGGTATTGATGATTATGGTTTA
GCAGAATTACAAGATATTTTGAAAAGTTTAGAAGCTTTTAATATTGACAAAAATCGTATTAGTCTTGACCTGGGAATTAG
TCGGGGTCTTCAATATTATACAGGTATGGTTTTTGAGATTTATGACAGCAAGTTAGGAGTAGAAAGAAAATTATGTGGTG
GAGGTAGATATGATGATTTGGTTGTCAGTTTAGGAGGTAAACAGGAAACTCCTGCCACTGGTTTTTCCTATCTCATGGAA
GAACTCAGAAAAGAATTAACAGAAAAAGCTCATTTGAGTTTCAATAATTATCAATTTGTTGAAGCTCTAGTAGTTGGTTT
GACTAGAGAAGATTATAGTGATTCTGTGAGAGTTGCTGAAAAATTAAGAAGCCTAGGCTTGCGAATAGAAACTGATGTTA
TTGGAAGAGATATTCAGAGTAATATTGAGTATGGAAATCAGCAGAAAATTTCATTTTTAATTATTGTAAACTCTACCGAA
AAAAAAGGTGGTAAGGTGCTTTTGCAAAATCTAGATTCAGGAGAACAAAAAAAATTAGAGTTGCATGAAGTAGTACATCA
AGTTAGAAATATTAAAGATAATACCAATTGTTAA

Upstream 100 bases:

>100_bases
TTGAATACATAATTATTTTTTTTTGAATATAGACAAAAATCAGCTATTAGTTTATTTGGATAGCGATCGCTTACCAAAGC
TAAAAATTAAAAAATATTTT

Downstream 100 bases:

>100_bases
AATTAATGCTATACTTAGGTAATACTTCAATTATTAAGTAATCAACATCTGCTCAATAACTCTTTTGAGAATAATGAGCT
AGTAGTACGTTAATTATTAT

Product: ATP phosphoribosyltransferase regulatory subunit

Products: NA

Alternate protein names: Histidine--tRNA ligase; HisRS [H]

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MQTIKVERVTGVNDILPSTYQIDQQIKSILSSNFESYGYRPIDVPLIEYTELYLKKSGEDIISRLYDFIYRNRRLCLRPE
FTASVVRAYLDNLQELPLPVRLYYMGPVFRYEQPQKEKYGQFTQMGIELIGATGAIADGEIISMACQGLDRLGLTEYQTF
IGHVGVLNNFLDHLQLDTRLRSFLLTQMETLRIEGKEIVESRLSEIYPAFKKNNFLAEQLDTNTTTKKITDILQNLEENE
ARTAIFKLLESMNIELTSTRTPEEIVDRLLIKIKHQDQTKELNQALEFMTELSQLKGEPQAIFKEIKKLLSAYGIDDYGL
AELQDILKSLEAFNIDKNRISLDLGISRGLQYYTGMVFEIYDSKLGVERKLCGGGRYDDLVVSLGGKQETPATGFSYLME
ELRKELTEKAHLSFNNYQFVEALVVGLTREDYSDSVRVAEKLRSLGLRIETDVIGRDIQSNIEYGNQQKISFLIIVNSTE
KKGGKVLLQNLDSGEQKKLELHEVVHQVRNIKDNTNC

Sequences:

>Translated_517_residues
MQTIKVERVTGVNDILPSTYQIDQQIKSILSSNFESYGYRPIDVPLIEYTELYLKKSGEDIISRLYDFIYRNRRLCLRPE
FTASVVRAYLDNLQELPLPVRLYYMGPVFRYEQPQKEKYGQFTQMGIELIGATGAIADGEIISMACQGLDRLGLTEYQTF
IGHVGVLNNFLDHLQLDTRLRSFLLTQMETLRIEGKEIVESRLSEIYPAFKKNNFLAEQLDTNTTTKKITDILQNLEENE
ARTAIFKLLESMNIELTSTRTPEEIVDRLLIKIKHQDQTKELNQALEFMTELSQLKGEPQAIFKEIKKLLSAYGIDDYGL
AELQDILKSLEAFNIDKNRISLDLGISRGLQYYTGMVFEIYDSKLGVERKLCGGGRYDDLVVSLGGKQETPATGFSYLME
ELRKELTEKAHLSFNNYQFVEALVVGLTREDYSDSVRVAEKLRSLGLRIETDVIGRDIQSNIEYGNQQKISFLIIVNSTE
KKGGKVLLQNLDSGEQKKLELHEVVHQVRNIKDNTNC
>Mature_517_residues
MQTIKVERVTGVNDILPSTYQIDQQIKSILSSNFESYGYRPIDVPLIEYTELYLKKSGEDIISRLYDFIYRNRRLCLRPE
FTASVVRAYLDNLQELPLPVRLYYMGPVFRYEQPQKEKYGQFTQMGIELIGATGAIADGEIISMACQGLDRLGLTEYQTF
IGHVGVLNNFLDHLQLDTRLRSFLLTQMETLRIEGKEIVESRLSEIYPAFKKNNFLAEQLDTNTTTKKITDILQNLEENE
ARTAIFKLLESMNIELTSTRTPEEIVDRLLIKIKHQDQTKELNQALEFMTELSQLKGEPQAIFKEIKKLLSAYGIDDYGL
AELQDILKSLEAFNIDKNRISLDLGISRGLQYYTGMVFEIYDSKLGVERKLCGGGRYDDLVVSLGGKQETPATGFSYLME
ELRKELTEKAHLSFNNYQFVEALVVGLTREDYSDSVRVAEKLRSLGLRIETDVIGRDIQSNIEYGNQQKISFLIIVNSTE
KKGGKVLLQNLDSGEQKKLELHEVVHQVRNIKDNTNC

Specific function: Unknown

COG id: COG0124

COG function: function code J; Histidyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1788861, Length=512, Percent_Identity=26.7578125, Blast_Score=157, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR015807
- InterPro:   IPR004516 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.21 [H]

Molecular weight: Translated: 59251; Mature: 59251

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00142 ZINC_PROTEASE ; PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTIKVERVTGVNDILPSTYQIDQQIKSILSSNFESYGYRPIDVPLIEYTELYLKKSGED
CCCEEEECCCCHHHHCCCHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHCCCHH
IISRLYDFIYRNRRLCLRPEFTASVVRAYLDNLQELPLPVRLYYMGPVFRYEQPQKEKYG
HHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHH
QFTQMGIELIGATGAIADGEIISMACQGLDRLGLTEYQTFIGHVGVLNNFLDHLQLDTRL
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSFLLTQMETLRIEGKEIVESRLSEIYPAFKKNNFLAEQLDTNTTTKKITDILQNLEENE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHH
ARTAIFKLLESMNIELTSTRTPEEIVDRLLIKIKHQDQTKELNQALEFMTELSQLKGEPQ
HHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHH
AIFKEIKKLLSAYGIDDYGLAELQDILKSLEAFNIDKNRISLDLGISRGLQYYTGMVFEI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCHHHCHHHHHHHHHEE
YDSKLGVERKLCGGGRYDDLVVSLGGKQETPATGFSYLMEELRKELTEKAHLSFNNYQFV
CCCCCCCCHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHH
EALVVGLTREDYSDSVRVAEKLRSLGLRIETDVIGRDIQSNIEYGNQQKISFLIIVNSTE
HHHHHHHHHCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCEEEEEEEEECCC
KKGGKVLLQNLDSGEQKKLELHEVVHQVRNIKDNTNC
CCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQTIKVERVTGVNDILPSTYQIDQQIKSILSSNFESYGYRPIDVPLIEYTELYLKKSGED
CCCEEEECCCCHHHHCCCHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHCCCHH
IISRLYDFIYRNRRLCLRPEFTASVVRAYLDNLQELPLPVRLYYMGPVFRYEQPQKEKYG
HHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHH
QFTQMGIELIGATGAIADGEIISMACQGLDRLGLTEYQTFIGHVGVLNNFLDHLQLDTRL
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSFLLTQMETLRIEGKEIVESRLSEIYPAFKKNNFLAEQLDTNTTTKKITDILQNLEENE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHH
ARTAIFKLLESMNIELTSTRTPEEIVDRLLIKIKHQDQTKELNQALEFMTELSQLKGEPQ
HHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHH
AIFKEIKKLLSAYGIDDYGLAELQDILKSLEAFNIDKNRISLDLGISRGLQYYTGMVFEI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCHHHCHHHHHHHHHEE
YDSKLGVERKLCGGGRYDDLVVSLGGKQETPATGFSYLMEELRKELTEKAHLSFNNYQFV
CCCCCCCCHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHH
EALVVGLTREDYSDSVRVAEKLRSLGLRIETDVIGRDIQSNIEYGNQQKISFLIIVNSTE
HHHHHHHHHCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCEEEEEEEEECCC
KKGGKVLLQNLDSGEQKKLELHEVVHQVRNIKDNTNC
CCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]