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The map label for this gene is mtdA [H]

Identifier: 110835492

GI number: 110835492

Start: 2979343

End: 2980416

Strand: Reverse

Name: mtdA [H]

Synonym: ABO_2631

Alternate gene names: 110835492

Gene position: 2980416-2979343 (Counterclockwise)

Preceding gene: 110835493

Following gene: 110835491

Centisome position: 95.52

GC content: 57.08

Gene sequence:

>1074_bases
ATGCAACGTTTTTGGGTAACCCTGGGCCTAGCACTGGCCTTGTGGGGCTGTGGAGAAGAGCCCCAGGCCGAGGCTCCCAT
GCCACAACCGGTGAAGCTGCAGACCGTCAATGGCGGCGATGGCACCTTGCGTCATTATCCAGGCAAGGTGGTGGCCACCG
AAGGGTCAGAGTTGGCTTTTCGGGTGTCCGGCCAGCTTGAGCGTCTTCCTGTGCGGGCCGGCGAGCAGGTTAAGAAAGGG
CAATTGCTGGCAGCGCTTGATCCGTCGGACTTTAAAAATCAGTTAGCCGATCGGCAAGCCCAGCATGATTTGGCCGAGAG
CCAGTATCAACGTGGTATCAGCCTGCGTGAGCGGGGCGTTATTTCTGAAGCTCAGTTCGATGAAATTGAAGCGAAGCGCC
GCCAAGCCCAGGCGGCTCTAAGCTTGGCCCGGGACAATGTGAACTACACTCGTCTGAAAGCGCCCTATGGCGGTACGGTG
GCACGCACCGAAGTGGAGAATTATCAATTCGTACAGGCCAAGCAGCCGATCCTCTACTTGCAGGGCGATAAAAATATCGA
TATCGAGTTCGCTGTTTCTGAGCGGTTTTTTACTAACGTACGCAAATTTTTTACCAAGATGCGTGAAGATTATCAGCCGA
GTGTGCGTTTCAAGGGGGCCCCGGATACCACTTTCAAAGCCCGATACAAAGAGCATGAGGCTAGTGCCGGGGATCGCACC
CAGACTTATATCATCACCCTGACGATGCCTAACCCGGAAGGCATCATGGTGCTGCCGGGAATGAGTGTGGATGTGGAGAT
TGATCTTAGCCAGATCATGCCGGGTACCGAGAAGGTGCCGGTAGTGCCGGCCGCGGCGGTATTCAACCCTGACGGCAAGG
AAGGCGCCCATGTGTGGAAGCATCAAGATGACGACACGGTGACGGCCGTGCCGGTCACCCTGGGTGAAGTTGTGGGCGGC
GGCGTCCAGATCACCGATGGGTTGCAGCCCGGAGATCGCATTGTGGCGGCCGGGGTTCATCGCCTGAAAGAAGGGCAGGC
GGTTCGTGAACTGGTGAAGGAACGGGGCCTGTAA

Upstream 100 bases:

>100_bases
GGTAAAAAAATAGCGCGGGTAAAAAGGTCAACGAGAAACGCTTGCACCTGTGCGATAATTTGGTACTAACAAGTACCGTT
TTTAGATCGGAGAGAGCACG

Downstream 100 bases:

>100_bases
ATGAACATTGCCGAGTACAGTATTCGCCACAAGGTGGTGAGCTGGCTGTTCACGCTGATCTTGTTGATCGGTGGGGTGGT
GAGCTTTACCCGCTTAGGGC

Product: multidrug ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MQRFWVTLGLALALWGCGEEPQAEAPMPQPVKLQTVNGGDGTLRHYPGKVVATEGSELAFRVSGQLERLPVRAGEQVKKG
QLLAALDPSDFKNQLADRQAQHDLAESQYQRGISLRERGVISEAQFDEIEAKRRQAQAALSLARDNVNYTRLKAPYGGTV
ARTEVENYQFVQAKQPILYLQGDKNIDIEFAVSERFFTNVRKFFTKMREDYQPSVRFKGAPDTTFKARYKEHEASAGDRT
QTYIITLTMPNPEGIMVLPGMSVDVEIDLSQIMPGTEKVPVVPAAAVFNPDGKEGAHVWKHQDDDTVTAVPVTLGEVVGG
GVQITDGLQPGDRIVAAGVHRLKEGQAVRELVKERGL

Sequences:

>Translated_357_residues
MQRFWVTLGLALALWGCGEEPQAEAPMPQPVKLQTVNGGDGTLRHYPGKVVATEGSELAFRVSGQLERLPVRAGEQVKKG
QLLAALDPSDFKNQLADRQAQHDLAESQYQRGISLRERGVISEAQFDEIEAKRRQAQAALSLARDNVNYTRLKAPYGGTV
ARTEVENYQFVQAKQPILYLQGDKNIDIEFAVSERFFTNVRKFFTKMREDYQPSVRFKGAPDTTFKARYKEHEASAGDRT
QTYIITLTMPNPEGIMVLPGMSVDVEIDLSQIMPGTEKVPVVPAAAVFNPDGKEGAHVWKHQDDDTVTAVPVTLGEVVGG
GVQITDGLQPGDRIVAAGVHRLKEGQAVRELVKERGL
>Mature_357_residues
MQRFWVTLGLALALWGCGEEPQAEAPMPQPVKLQTVNGGDGTLRHYPGKVVATEGSELAFRVSGQLERLPVRAGEQVKKG
QLLAALDPSDFKNQLADRQAQHDLAESQYQRGISLRERGVISEAQFDEIEAKRRQAQAALSLARDNVNYTRLKAPYGGTV
ARTEVENYQFVQAKQPILYLQGDKNIDIEFAVSERFFTNVRKFFTKMREDYQPSVRFKGAPDTTFKARYKEHEASAGDRT
QTYIITLTMPNPEGIMVLPGMSVDVEIDLSQIMPGTEKVPVVPAAAVFNPDGKEGAHVWKHQDDDTVTAVPVTLGEVVGG
GVQITDGLQPGDRIVAAGVHRLKEGQAVRELVKERGL

Specific function: The periplasmic linker component of an organic solvent efflux pump. Involved in export of a number of organic solvents, including toluene and styrene. This is the most important solvent efflux pump in this strain, although it can export AMP and some antib

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081796, Length=376, Percent_Identity=27.1276595744681, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1789665, Length=368, Percent_Identity=23.6413043478261, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39395; Mature: 39395

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRFWVTLGLALALWGCGEEPQAEAPMPQPVKLQTVNGGDGTLRHYPGKVVATEGSELAF
CCEEEEHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEECCCEEEEECCCEEEE
RVSGQLERLPVRAGEQVKKGQLLAALDPSDFKNQLADRQAQHDLAESQYQRGISLRERGV
EECCCCEECCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
ISEAQFDEIEAKRRQAQAALSLARDNVNYTRLKAPYGGTVARTEVENYQFVQAKQPILYL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCEEEEECCCCEEEE
QGDKNIDIEFAVSERFFTNVRKFFTKMREDYQPSVRFKGAPDTTFKARYKEHEASAGDRT
ECCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHCCCCCCCC
QTYIITLTMPNPEGIMVLPGMSVDVEIDLSQIMPGTEKVPVVPAAAVFNPDGKEGAHVWK
EEEEEEEEECCCCCEEEECCCEEEEEEEHHHCCCCCCCCCCEEEEEEECCCCCCCCEECC
HQDDDTVTAVPVTLGEVVGGGVQITDGLQPGDRIVAAGVHRLKEGQAVRELVKERGL
CCCCCCEEEEEEEHHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure
MQRFWVTLGLALALWGCGEEPQAEAPMPQPVKLQTVNGGDGTLRHYPGKVVATEGSELAF
CCEEEEHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEECCCEEEEECCCEEEE
RVSGQLERLPVRAGEQVKKGQLLAALDPSDFKNQLADRQAQHDLAESQYQRGISLRERGV
EECCCCEECCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
ISEAQFDEIEAKRRQAQAALSLARDNVNYTRLKAPYGGTVARTEVENYQFVQAKQPILYL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCEEEEECCCCEEEE
QGDKNIDIEFAVSERFFTNVRKFFTKMREDYQPSVRFKGAPDTTFKARYKEHEASAGDRT
ECCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHCCCCCCCC
QTYIITLTMPNPEGIMVLPGMSVDVEIDLSQIMPGTEKVPVVPAAAVFNPDGKEGAHVWK
EEEEEEEEECCCCCEEEECCCEEEEEEEHHHCCCCCCCCCCEEEEEEECCCCCCCCEECC
HQDDDTVTAVPVTLGEVVGGGVQITDGLQPGDRIVAAGVHRLKEGQAVRELVKERGL
CCCCCCEEEEEEEHHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11395460 [H]