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The map label for this gene is ahpF [H]

Identifier: 110835291

GI number: 110835291

Start: 2749791

End: 2751407

Strand: Reverse

Name: ahpF [H]

Synonym: ABO_2430

Alternate gene names: 110835291

Gene position: 2751407-2749791 (Counterclockwise)

Preceding gene: 110835292

Following gene: 110835290

Centisome position: 88.18

GC content: 51.76

Gene sequence:

>1617_bases
ATGCTCACGAATGAAATTTTGCAGGCTCTTAAGGGCTACGCCGCCAACATGCAGAAGAAAGTCTCTTTTGTGCTGCAAAG
CGGATCCCATGACAAACGCGAGGAACTGGTAACGTTTCTTTCCAGTATCGCGGGTGTCAGTGACAATCTCGCGTTCGAAG
AACGGGATCTGGGTGACAGGCTCCGTAGTCCAATCAGTTTTCTGTTAGAAGCCGATGGTGAAGACACCGGTATCCGTTTC
TCCGGTATTCCCGCAGGCCATGAATTCAATTCCTTGGTGTTAGCGTTTCTACATGCATCTGGGACCGAAATTAAACTGGA
CGCGGGTCTTCAGCGCATGGTGGCTAAGGCCAAAGGCGACATGCATTTTGAAGTGTTTATTAGCCTGAGCTGCCATAACT
GCCCAGATGTGGTTCAGGCGCTGAATCAGTTCGCCTTGTTGAACCCCAATATCCGTACGGAAATGATCGACGGGGGGTTG
TTTCAGGATGTGGTCAGTGACAGGAACATTCAGGGTGTGCCCAGCGTTTACTTGAACGGCGAGTTGTTCGCCAATGGCAA
GGTTACCGCCGCTGAGTTGATCGATAAGCTGTTGGCCTACGACCCAAGCCTCGCTGAAGCCGGTGTCGGAGAAAAACTGC
CATTGCAGGACGTTACCGTTATCGGGGGCGGCCCGGCGGGTGTTTCCGCCGCAATTTACAGCGCCCGTAAAGGTTTGAAG
GTCACCCTGATCGCCGATCGTATTGGTGGGCAGGTGAAAGACACCATGGATATCGAAAACCTGATCTCCGTAAAGAAAAC
CACCGGCCCGGAACTGTCTGGTGCGCTGCAGGCGCATATGAGCGAATACGATGTGACAGTAAAAGAGCATCTGAGAGTGG
CTCGTGTGGAGAAAGGCGATATTAAGACCGTGGTTTTGTCTTCCGGTGAAGCTATCGACACCAAGACGATTATCGTGGCC
ACCGGCGCCAAGTGGCGCGAACTGGGTGTGCCTGGTGAAAAGGAAAATATCGGCAATGGTGTGGCTTACTGCCCACACTG
TGATGGTCCCTTCTTCAAGGGCAAGGATGTCGCTGTCATTGGTGGTGGCAACTCTGGCATCGAAGCTGCGCTGGATTTGG
CCGGTATCGTTAAATCAGTGAATGTATTCGAGTTCATGCCAGAGCTGAAAGCGGACAAGGTGCTGGTGGACAAGGCTGAA
GCCAAAGCCAACATTACCATTCACCGGAACGTGGCAACCAATCAGATAATGGCCAGTAACGGCAAGGTAGATGCCATTGA
ATACATTGACCGTGATACTGAGCAATTACATCGACTGCCCTTGCATGGGGTGTTTGTGCAGATCGGACTGGTGCCCAACA
GTGACTTTCTAGAAGGGGTGGTTGAGCGTAGTCGGTTTGGAGAAATTGAAATCAACGAGAAGTGCCAGACATCGCAAGAG
GGAATTTATGCGGCTGGTGATGTGACCACCGTGCCGTACAAACAGATTGTTATTAGTATGGGCGAAGGCTCCAAGGCTTC
CCTGGCTGCTTTTGAATACCTGCTGACACAGAGCGATCGTCTTGATGCCCTGTATGAAAATGACAAGGATGTGCAGAAGG
TCGCAGCGGTTGCCTGA

Upstream 100 bases:

>100_bases
ATCTCGCTTCCGATTGTAACAACCCTAGCGACAGTGCCGGGGTTGTTACCCCTTGAATGCTTAAGTTAATGAACACTCTA
TTTATAGTGAGGGGATACCC

Downstream 100 bases:

>100_bases
CCCCAGCGCTAAAAGAGAAAGTCACGGGCATACATAGCGGAAAACGGTACCTTATATTTGCCGCAATCGCTTGCCCTAGC
CAGTGCTACCGGCATGGCGC

Product: Alkyl hydroperoxide reductase subunit F

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase [H]

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MLTNEILQALKGYAANMQKKVSFVLQSGSHDKREELVTFLSSIAGVSDNLAFEERDLGDRLRSPISFLLEADGEDTGIRF
SGIPAGHEFNSLVLAFLHASGTEIKLDAGLQRMVAKAKGDMHFEVFISLSCHNCPDVVQALNQFALLNPNIRTEMIDGGL
FQDVVSDRNIQGVPSVYLNGELFANGKVTAAELIDKLLAYDPSLAEAGVGEKLPLQDVTVIGGGPAGVSAAIYSARKGLK
VTLIADRIGGQVKDTMDIENLISVKKTTGPELSGALQAHMSEYDVTVKEHLRVARVEKGDIKTVVLSSGEAIDTKTIIVA
TGAKWRELGVPGEKENIGNGVAYCPHCDGPFFKGKDVAVIGGGNSGIEAALDLAGIVKSVNVFEFMPELKADKVLVDKAE
AKANITIHRNVATNQIMASNGKVDAIEYIDRDTEQLHRLPLHGVFVQIGLVPNSDFLEGVVERSRFGEIEINEKCQTSQE
GIYAAGDVTTVPYKQIVISMGEGSKASLAAFEYLLTQSDRLDALYENDKDVQKVAAVA

Sequences:

>Translated_538_residues
MLTNEILQALKGYAANMQKKVSFVLQSGSHDKREELVTFLSSIAGVSDNLAFEERDLGDRLRSPISFLLEADGEDTGIRF
SGIPAGHEFNSLVLAFLHASGTEIKLDAGLQRMVAKAKGDMHFEVFISLSCHNCPDVVQALNQFALLNPNIRTEMIDGGL
FQDVVSDRNIQGVPSVYLNGELFANGKVTAAELIDKLLAYDPSLAEAGVGEKLPLQDVTVIGGGPAGVSAAIYSARKGLK
VTLIADRIGGQVKDTMDIENLISVKKTTGPELSGALQAHMSEYDVTVKEHLRVARVEKGDIKTVVLSSGEAIDTKTIIVA
TGAKWRELGVPGEKENIGNGVAYCPHCDGPFFKGKDVAVIGGGNSGIEAALDLAGIVKSVNVFEFMPELKADKVLVDKAE
AKANITIHRNVATNQIMASNGKVDAIEYIDRDTEQLHRLPLHGVFVQIGLVPNSDFLEGVVERSRFGEIEINEKCQTSQE
GIYAAGDVTTVPYKQIVISMGEGSKASLAAFEYLLTQSDRLDALYENDKDVQKVAAVA
>Mature_538_residues
MLTNEILQALKGYAANMQKKVSFVLQSGSHDKREELVTFLSSIAGVSDNLAFEERDLGDRLRSPISFLLEADGEDTGIRF
SGIPAGHEFNSLVLAFLHASGTEIKLDAGLQRMVAKAKGDMHFEVFISLSCHNCPDVVQALNQFALLNPNIRTEMIDGGL
FQDVVSDRNIQGVPSVYLNGELFANGKVTAAELIDKLLAYDPSLAEAGVGEKLPLQDVTVIGGGPAGVSAAIYSARKGLK
VTLIADRIGGQVKDTMDIENLISVKKTTGPELSGALQAHMSEYDVTVKEHLRVARVEKGDIKTVVLSSGEAIDTKTIIVA
TGAKWRELGVPGEKENIGNGVAYCPHCDGPFFKGKDVAVIGGGNSGIEAALDLAGIVKSVNVFEFMPELKADKVLVDKAE
AKANITIHRNVATNQIMASNGKVDAIEYIDRDTEQLHRLPLHGVFVQIGLVPNSDFLEGVVERSRFGEIEINEKCQTSQE
GIYAAGDVTTVPYKQIVISMGEGSKASLAAFEYLLTQSDRLDALYENDKDVQKVAAVA

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone [H]

COG id: COG3634

COG function: function code O; Alkyl hydroperoxide reductase, large subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081763, Length=522, Percent_Identity=48.4674329501916, Blast_Score=476, Evalue=1e-135,
Organism=Escherichia coli, GI1787114, Length=308, Percent_Identity=33.4415584415584, Blast_Score=149, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6321898, Length=316, Percent_Identity=31.0126582278481, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6320560, Length=313, Percent_Identity=31.3099041533546, Blast_Score=124, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012081
- InterPro:   IPR013027
- InterPro:   IPR002109
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 57831; Mature: 57831

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTNEILQALKGYAANMQKKVSFVLQSGSHDKREELVTFLSSIAGVSDNLAFEERDLGDR
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LRSPISFLLEADGEDTGIRFSGIPAGHEFNSLVLAFLHASGTEIKLDAGLQRMVAKAKGD
HHHHHHHHEECCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCC
MHFEVFISLSCHNCPDVVQALNQFALLNPNIRTEMIDGGLFQDVVSDRNIQGVPSVYLNG
EEEEEEEEEECCCCHHHHHHHHHHEECCCCCCCEECCCHHHHHHHCCCCCCCCCEEEECC
ELFANGKVTAAELIDKLLAYDPSLAEAGVGEKLPLQDVTVIGGGPAGVSAAIYSARKGLK
EEEECCCEEHHHHHHHHHHCCCCHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCE
VTLIADRIGGQVKDTMDIENLISVKKTTGPELSGALQAHMSEYDVTVKEHLRVARVEKGD
EEEEEHHCCCCCHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
IKTVVLSSGEAIDTKTIIVATGAKWRELGVPGEKENIGNGVAYCPHCDGPFFKGKDVAVI
EEEEEEECCCEECCEEEEEECCCCHHCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEEE
GGGNSGIEAALDLAGIVKSVNVFEFMPELKADKVLVDKAEAKANITIHRNVATNQIMASN
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEECCCCCEEEECC
GKVDAIEYIDRDTEQLHRLPLHGVFVQIGLVPNSDFLEGVVERSRFGEIEINEKCQTSQE
CCEEHHHHHCCCHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHCCCEEECCCCCCCCC
GIYAAGDVTTVPYKQIVISMGEGSKASLAAFEYLLTQSDRLDALYENDKDVQKVAAVA
CEEEECCEEECCHHHEEEECCCCCCHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure
MLTNEILQALKGYAANMQKKVSFVLQSGSHDKREELVTFLSSIAGVSDNLAFEERDLGDR
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LRSPISFLLEADGEDTGIRFSGIPAGHEFNSLVLAFLHASGTEIKLDAGLQRMVAKAKGD
HHHHHHHHEECCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCC
MHFEVFISLSCHNCPDVVQALNQFALLNPNIRTEMIDGGLFQDVVSDRNIQGVPSVYLNG
EEEEEEEEEECCCCHHHHHHHHHHEECCCCCCCEECCCHHHHHHHCCCCCCCCCEEEECC
ELFANGKVTAAELIDKLLAYDPSLAEAGVGEKLPLQDVTVIGGGPAGVSAAIYSARKGLK
EEEECCCEEHHHHHHHHHHCCCCHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCE
VTLIADRIGGQVKDTMDIENLISVKKTTGPELSGALQAHMSEYDVTVKEHLRVARVEKGD
EEEEEHHCCCCCHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
IKTVVLSSGEAIDTKTIIVATGAKWRELGVPGEKENIGNGVAYCPHCDGPFFKGKDVAVI
EEEEEEECCCEECCEEEEEECCCCHHCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEEE
GGGNSGIEAALDLAGIVKSVNVFEFMPELKADKVLVDKAEAKANITIHRNVATNQIMASN
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEECCCCCEEEECC
GKVDAIEYIDRDTEQLHRLPLHGVFVQIGLVPNSDFLEGVVERSRFGEIEINEKCQTSQE
CCEEHHHHHCCCHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHCCCEEECCCCCCCCC
GIYAAGDVTTVPYKQIVISMGEGSKASLAAFEYLLTQSDRLDALYENDKDVQKVAAVA
CEEEECCEEECCHHHEEEECCCCCCHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1917890; 2760020 [H]