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The map label for this gene is ahpC [H]

Identifier: 110835292

GI number: 110835292

Start: 2751507

End: 2752070

Strand: Reverse

Name: ahpC [H]

Synonym: ABO_2431

Alternate gene names: 110835292

Gene position: 2752070-2751507 (Counterclockwise)

Preceding gene: 110835294

Following gene: 110835291

Centisome position: 88.2

GC content: 51.6

Gene sequence:

>564_bases
ATGGCACTGATCAACAGCGAAATCCAACCGTTCAACGCCACCGCATTCAAGCAGGGCGAATTTGTAGACATTTCAGAAGC
GGATGTTAAGGGAAAGTGGGCGATCTTCTTTTTCTATCCCGCCGACTTCACCTTTGTTTGCCCTACTGAGTTGGGCGATG
TGGCCGACAAGTATGAAGAGCTGCAGAAAATGGGCGTAGAAGTCTTCTCTGTATCCACCGATACCCACTTCACCCACAAA
GCATGGCACGACACCTCCGACACCATCGGCAAGATTAATTACTTCATGGTGGGAGACCAGACCGGCAACATCACCAATAA
CTTTGGTGTAATGCGTGAAGGCCAAGGCCTGGCTGACCGCGCTACCTTCCTGATTGATCCAGATGGTGTAATCCAGGCAA
TGGAAATTACAGCTGAAGGTATCGGCCGTGATGCGGACGATCTGCTGCGCAAGGTAAAAGCGGCCCAGTATGTTCGCAAC
AACCCTGGCGAAGTTTGCCCGGCGAAATGGAAAGAAGGTGAAGCCACTCTTGCCCCGTCTCTGGACTTGGTCGGCAAGAT
CTAA

Upstream 100 bases:

>100_bases
AAGCATCCAAATTTACCAATCGCCATAAAGGCCCCATTCTTGTTCTCGACGAAAACATTAACGCAATCGTTTTACCGATA
ACTTAGGGAGTCTTGGACAC

Downstream 100 bases:

>100_bases
TCTCGCTTCCGATTGTAACAACCCTAGCGACAGTGCCGGGGTTGTTACCCCTTGAATGCTTAAGTTAATGAACACTCTAT
TTATAGTGAGGGGATACCCA

Product: alkyl hydroperoxide reductase subunit C

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MALINSEIQPFNATAFKQGEFVDISEADVKGKWAIFFFYPADFTFVCPTELGDVADKYEELQKMGVEVFSVSTDTHFTHK
AWHDTSDTIGKINYFMVGDQTGNITNNFGVMREGQGLADRATFLIDPDGVIQAMEITAEGIGRDADDLLRKVKAAQYVRN
NPGEVCPAKWKEGEATLAPSLDLVGKI

Sequences:

>Translated_187_residues
MALINSEIQPFNATAFKQGEFVDISEADVKGKWAIFFFYPADFTFVCPTELGDVADKYEELQKMGVEVFSVSTDTHFTHK
AWHDTSDTIGKINYFMVGDQTGNITNNFGVMREGQGLADRATFLIDPDGVIQAMEITAEGIGRDADDLLRKVKAAQYVRN
NPGEVCPAKWKEGEATLAPSLDLVGKI
>Mature_186_residues
ALINSEIQPFNATAFKQGEFVDISEADVKGKWAIFFFYPADFTFVCPTELGDVADKYEELQKMGVEVFSVSTDTHFTHKA
WHDTSDTIGKINYFMVGDQTGNITNNFGVMREGQGLADRATFLIDPDGVIQAMEITAEGIGRDADDLLRKVKAAQYVRNN
PGEVCPAKWKEGEATLAPSLDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=179, Percent_Identity=44.6927374301676, Blast_Score=162, Evalue=1e-40,
Organism=Homo sapiens, GI5802974, Length=173, Percent_Identity=45.6647398843931, Blast_Score=162, Evalue=1e-40,
Organism=Homo sapiens, GI32189392, Length=184, Percent_Identity=40.2173913043478, Blast_Score=150, Evalue=5e-37,
Organism=Homo sapiens, GI4505591, Length=175, Percent_Identity=41.1428571428571, Blast_Score=147, Evalue=7e-36,
Organism=Homo sapiens, GI32455266, Length=175, Percent_Identity=41.1428571428571, Blast_Score=147, Evalue=7e-36,
Organism=Homo sapiens, GI32455264, Length=175, Percent_Identity=41.1428571428571, Blast_Score=147, Evalue=7e-36,
Organism=Homo sapiens, GI5453549, Length=189, Percent_Identity=39.1534391534392, Blast_Score=139, Evalue=1e-33,
Organism=Homo sapiens, GI33188454, Length=74, Percent_Identity=48.6486486486487, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI4758638, Length=157, Percent_Identity=26.1146496815287, Blast_Score=68, Evalue=6e-12,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=74.331550802139, Blast_Score=310, Evalue=4e-86,
Organism=Caenorhabditis elegans, GI193204376, Length=183, Percent_Identity=39.344262295082, Blast_Score=144, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI32565831, Length=183, Percent_Identity=39.344262295082, Blast_Score=144, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17554494, Length=177, Percent_Identity=40.1129943502825, Blast_Score=144, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI25153706, Length=164, Percent_Identity=28.0487804878049, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323613, Length=185, Percent_Identity=33.5135135135135, Blast_Score=119, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6320661, Length=184, Percent_Identity=32.0652173913043, Blast_Score=117, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6319407, Length=158, Percent_Identity=26.5822784810127, Blast_Score=69, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21357347, Length=180, Percent_Identity=37.2222222222222, Blast_Score=139, Evalue=1e-33,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=35.5932203389831, Blast_Score=137, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24656348, Length=182, Percent_Identity=38.4615384615385, Blast_Score=137, Evalue=4e-33,
Organism=Drosophila melanogaster, GI17864676, Length=182, Percent_Identity=38.4615384615385, Blast_Score=137, Evalue=4e-33,
Organism=Drosophila melanogaster, GI17157991, Length=180, Percent_Identity=36.6666666666667, Blast_Score=130, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24641739, Length=180, Percent_Identity=36.6666666666667, Blast_Score=130, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24581278, Length=154, Percent_Identity=32.4675324675325, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17975518, Length=156, Percent_Identity=28.8461538461538, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24652436, Length=161, Percent_Identity=29.1925465838509, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24652434, Length=156, Percent_Identity=28.8461538461538, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20651; Mature: 20520

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALINSEIQPFNATAFKQGEFVDISEADVKGKWAIFFFYPADFTFVCPTELGDVADKYEE
CCCCCCCCCCCCCCEECCCCEEECCCCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHH
LQKMGVEVFSVSTDTHFTHKAWHDTSDTIGKINYFMVGDQTGNITNNFGVMREGQGLADR
HHHCCCEEEEEECCCCEEECCCCCCCCCCEEEEEEEEECCCCCCCCCCCCEECCCCCCCC
ATFLIDPDGVIQAMEITAEGIGRDADDLLRKVKAAQYVRNNPGEVCPAKWKEGEATLAPS
EEEEECCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCC
LDLVGKI
CHHCCCC
>Mature Secondary Structure 
ALINSEIQPFNATAFKQGEFVDISEADVKGKWAIFFFYPADFTFVCPTELGDVADKYEE
CCCCCCCCCCCCCEECCCCEEECCCCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHH
LQKMGVEVFSVSTDTHFTHKAWHDTSDTIGKINYFMVGDQTGNITNNFGVMREGQGLADR
HHHCCCEEEEEECCCCEEECCCCCCCCCCEEEEEEEEECCCCCCCCCCCCEECCCCCCCC
ATFLIDPDGVIQAMEITAEGIGRDADDLLRKVKAAQYVRNNPGEVCPAKWKEGEATLAPS
EEEEECCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCC
LDLVGKI
CHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]