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The map label for this gene is nahR [H]

Identifier: 110835263

GI number: 110835263

Start: 2723658

End: 2724590

Strand: Reverse

Name: nahR [H]

Synonym: ABO_2402

Alternate gene names: 110835263

Gene position: 2724590-2723658 (Counterclockwise)

Preceding gene: 110835266

Following gene: 110835262

Centisome position: 87.32

GC content: 62.7

Gene sequence:

>933_bases
ATGCATGTTTCGCGATTCGACCTGAACCTTTTCGTGGTCTTCGACGCCATCTATACCGAAGGGTCGCTGACCCGCGCTGC
CAAGGTGCTCAACCTCACCCAGCCAGCGGTTAGCCATGCCTTGGCGCGCTTGCGCGCCCGCCTAAACGACCCGCTATTTG
TTCGCCAGGGCAGCCGCATGGTACCCACCGCTCGGGCTCGGGCCATGGTGAGCCCGGTGCGCCACGCGCTGGGCGGTTTT
CAGCGTTGCCTCAGTGAAGAGGGCGGCTTCGATGCCAGTGAAGCGGAGCGTACGTTTGTATTGGGCCTGCGCGATGGGCT
GGAAGCGCGGTTGCTGCCCGCCTTGATGAGCCAGTTTATGGATGAAGCGCCGGGCATCAAACTGCAATCGTTAACCGTGA
GCCGCCGGCAAATGGCCACGGAACTGGCCAGTGGTCGGCTGGATTTAGCCTGCGATGTGATGCTGGCGCTGCCCGAAGCC
ATTGAGCATCAGGTGGTATTGGAAGGGCCGCTGGTGGTGCTGATGCGTGAATCGCACCCGTTGGCCCAGGGCATGGACCT
GCCCGATTATCTCGCCGCCCAGCATGTGCTGGTGTCATCCCGCCGCGAAGGGCCGGGGTTGGAAGATTTCGGCCTGGCAC
GGCAAGGCTATCGCCGGCACATTCGTTTGCGCTGCCAGCATTACCAGGCCGCGTTGAGCACCGTGCAACAAACCGACTTG
CTGCTCACTATGCCCGCCAGCCTGGCCGGGCAGCTGAGCGATCAGGGGCTGGTATGGAAGCCGTTCCCTGGGGGATTGCC
GGGGCTGGAAATGCACCTGTATTGGCACCGCGACCAGAGTGCCGACCCGGCTCACAGTTGGCTGCGCCAACGGGTGCTGG
CGCAACTGGAAGTCATGCAAAACGACATTCAGCTCAGCGCCTCTGCTGTGTAG

Upstream 100 bases:

>100_bases
GTATCCGTAGGCCAGCCGCCAGCACTTATCCATTGACCGATGCTAGAGAGCGCGTTTCAATAAATCCAATGAATCATGGC
AATTATTTTGGATAAGTTTC

Downstream 100 bases:

>100_bases
AGGCTTTGTCGGACGCGAACGAAATCACCTGCGGGCTCAACGAGGCGGGTCTGGATGCGCAAGTCTGGCTGGATCAAGCT
GATACCGGCGAAGTGAAAGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MHVSRFDLNLFVVFDAIYTEGSLTRAAKVLNLTQPAVSHALARLRARLNDPLFVRQGSRMVPTARARAMVSPVRHALGGF
QRCLSEEGGFDASEAERTFVLGLRDGLEARLLPALMSQFMDEAPGIKLQSLTVSRRQMATELASGRLDLACDVMLALPEA
IEHQVVLEGPLVVLMRESHPLAQGMDLPDYLAAQHVLVSSRREGPGLEDFGLARQGYRRHIRLRCQHYQAALSTVQQTDL
LLTMPASLAGQLSDQGLVWKPFPGGLPGLEMHLYWHRDQSADPAHSWLRQRVLAQLEVMQNDIQLSASAV

Sequences:

>Translated_310_residues
MHVSRFDLNLFVVFDAIYTEGSLTRAAKVLNLTQPAVSHALARLRARLNDPLFVRQGSRMVPTARARAMVSPVRHALGGF
QRCLSEEGGFDASEAERTFVLGLRDGLEARLLPALMSQFMDEAPGIKLQSLTVSRRQMATELASGRLDLACDVMLALPEA
IEHQVVLEGPLVVLMRESHPLAQGMDLPDYLAAQHVLVSSRREGPGLEDFGLARQGYRRHIRLRCQHYQAALSTVQQTDL
LLTMPASLAGQLSDQGLVWKPFPGGLPGLEMHLYWHRDQSADPAHSWLRQRVLAQLEVMQNDIQLSASAV
>Mature_310_residues
MHVSRFDLNLFVVFDAIYTEGSLTRAAKVLNLTQPAVSHALARLRARLNDPLFVRQGSRMVPTARARAMVSPVRHALGGF
QRCLSEEGGFDASEAERTFVLGLRDGLEARLLPALMSQFMDEAPGIKLQSLTVSRRQMATELASGRLDLACDVMLALPEA
IEHQVVLEGPLVVLMRESHPLAQGMDLPDYLAAQHVLVSSRREGPGLEDFGLARQGYRRHIRLRCQHYQAALSTVQQTDL
LLTMPASLAGQLSDQGLVWKPFPGGLPGLEMHLYWHRDQSADPAHSWLRQRVLAQLEVMQNDIQLSASAV

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=303, Percent_Identity=30.3630363036304, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI87081766, Length=287, Percent_Identity=26.4808362369338, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786820, Length=285, Percent_Identity=23.5087719298246, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790147, Length=296, Percent_Identity=28.3783783783784, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787601, Length=276, Percent_Identity=22.8260869565217, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787879, Length=291, Percent_Identity=25.4295532646048, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34355; Mature: 34355

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVSRFDLNLFVVFDAIYTEGSLTRAAKVLNLTQPAVSHALARLRARLNDPLFVRQGSRM
CCCEEEECEEEEEEEHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEECCCCC
VPTARARAMVSPVRHALGGFQRCLSEEGGFDASEAERTFVLGLRDGLEARLLPALMSQFM
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHH
DEAPGIKLQSLTVSRRQMATELASGRLDLACDVMLALPEAIEHQVVLEGPLVVLMRESHP
HHCCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEECCCEEEEEECCCC
LAQGMDLPDYLAAQHVLVSSRREGPGLEDFGLARQGYRRHIRLRCQHYQAALSTVQQTDL
HHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCE
LLTMPASLAGQLSDQGLVWKPFPGGLPGLEMHLYWHRDQSADPAHSWLRQRVLAQLEVMQ
EEECCHHHHHCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
NDIQLSASAV
HHHHHHCCCC
>Mature Secondary Structure
MHVSRFDLNLFVVFDAIYTEGSLTRAAKVLNLTQPAVSHALARLRARLNDPLFVRQGSRM
CCCEEEECEEEEEEEHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEECCCCC
VPTARARAMVSPVRHALGGFQRCLSEEGGFDASEAERTFVLGLRDGLEARLLPALMSQFM
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHH
DEAPGIKLQSLTVSRRQMATELASGRLDLACDVMLALPEAIEHQVVLEGPLVVLMRESHP
HHCCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEECCCEEEEEECCCC
LAQGMDLPDYLAAQHVLVSSRREGPGLEDFGLARQGYRRHIRLRCQHYQAALSTVQQTDL
HHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCE
LLTMPASLAGQLSDQGLVWKPFPGGLPGLEMHLYWHRDQSADPAHSWLRQRVLAQLEVMQ
EEECCHHHHHCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
NDIQLSASAV
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]