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The map label for this gene is actR [H]

Identifier: 110636365

GI number: 110636365

Start: 4348434

End: 4349000

Strand: Reverse

Name: actR [H]

Synonym: Meso_4041

Alternate gene names: 110636365

Gene position: 4349000-4348434 (Counterclockwise)

Preceding gene: 110636366

Following gene: 110636362

Centisome position: 98.56

GC content: 61.9

Gene sequence:

>567_bases
ATGAACGATACGACAGCCGAACAGGCCAATAATATTCCCGGCGAGGATCGCACCCTTCTCATTGTTGAAGACGATCGGCC
TTTTCTTGCGCGTCTTGCGCGCGCCATGGAGGGCCGGGGCTTCATGGTCGACACAGCCGAGAGCGTCGAGGAAGCGATCG
CCAAGGTGAAGGCGGCGCCGCCCGCCTTTGCGGTGATCGATATGAGGCTTGGCGACGGCAACGGGCTCGATGTTGTTTCC
GCTCTCCGCGATAAGCGGGAGGATGCCCGCGCAATCGTGCTTACCGGGTACGGCAATATCGCCACCGCTGTGACAGCGGT
GAAGCTCGGCGCAATCGATTATCTCTCCAAGCCCGCCGATGCGGACGATATTTACGCCGCACTCATGCGCATGCCAGGTG
TCAAGGCGGAGCCGCCGGAAAACCCGATGTCGGCCGACCGGGTGCGCTGGGAGCATATTCAGCGCGTCTATGAGATGTGC
GATCGCAATGTTTCGGAAACGGCGCGGCGGCTCAACATGCATCGCCGCACGCTGCAACGCATCCTAGCCAAGCGCGCGCC
GCGCTGA

Upstream 100 bases:

>100_bases
CGCCGGAGGCGAAGCCTCCGCGCAAGGCTATCAGAAATAACAAAAGCTGGAAAAACGCGGCTTCCTTTCCTAAATTCTTG
CATATATCAGCGGGGCCATG

Downstream 100 bases:

>100_bases
ACTCTCCCGCTTAAAAATCTTCGCGATCCAGCATCGGCACGGGAACACCGGCAAGCTCGGCCGCGGTAAGCCGCGCGGCC
CCAACGCGGGCAAAGCGCAG

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MNDTTAEQANNIPGEDRTLLIVEDDRPFLARLARAMEGRGFMVDTAESVEEAIAKVKAAPPAFAVIDMRLGDGNGLDVVS
ALRDKREDARAIVLTGYGNIATAVTAVKLGAIDYLSKPADADDIYAALMRMPGVKAEPPENPMSADRVRWEHIQRVYEMC
DRNVSETARRLNMHRRTLQRILAKRAPR

Sequences:

>Translated_188_residues
MNDTTAEQANNIPGEDRTLLIVEDDRPFLARLARAMEGRGFMVDTAESVEEAIAKVKAAPPAFAVIDMRLGDGNGLDVVS
ALRDKREDARAIVLTGYGNIATAVTAVKLGAIDYLSKPADADDIYAALMRMPGVKAEPPENPMSADRVRWEHIQRVYEMC
DRNVSETARRLNMHRRTLQRILAKRAPR
>Mature_188_residues
MNDTTAEQANNIPGEDRTLLIVEDDRPFLARLARAMEGRGFMVDTAESVEEAIAKVKAAPPAFAVIDMRLGDGNGLDVVS
ALRDKREDARAIVLTGYGNIATAVTAVKLGAIDYLSKPADADDIYAALMRMPGVKAEPPENPMSADRVRWEHIQRVYEMC
DRNVSETARRLNMHRRTLQRILAKRAPR

Specific function: Member of the two-component regulatory system ActS/ActR acting in acid tolerance. These data implicate that a two- component sensor may be involved in pH sensing and/or response [H]

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=125, Percent_Identity=29.6, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 20832; Mature: 20832

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTTAEQANNIPGEDRTLLIVEDDRPFLARLARAMEGRGFMVDTAESVEEAIAKVKAAP
CCCCCCHHHCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHCCC
PAFAVIDMRLGDGNGLDVVSALRDKREDARAIVLTGYGNIATAVTAVKLGAIDYLSKPAD
CCEEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCC
ADDIYAALMRMPGVKAEPPENPMSADRVRWEHIQRVYEMCDRNVSETARRLNMHRRTLQR
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ILAKRAPR
HHHHCCCC
>Mature Secondary Structure
MNDTTAEQANNIPGEDRTLLIVEDDRPFLARLARAMEGRGFMVDTAESVEEAIAKVKAAP
CCCCCCHHHCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHCCC
PAFAVIDMRLGDGNGLDVVSALRDKREDARAIVLTGYGNIATAVTAVKLGAIDYLSKPAD
CCEEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCC
ADDIYAALMRMPGVKAEPPENPMSADRVRWEHIQRVYEMCDRNVSETARRLNMHRRTLQR
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ILAKRAPR
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]