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The map label for this gene is regB [H]

Identifier: 110636366

GI number: 110636366

Start: 4349061

End: 4350386

Strand: Reverse

Name: regB [H]

Synonym: Meso_4042

Alternate gene names: 110636366

Gene position: 4350386-4349061 (Counterclockwise)

Preceding gene: 110636367

Following gene: 110636365

Centisome position: 98.59

GC content: 62.67

Gene sequence:

>1326_bases
ATGCTGGAAGAACAAAGAACGCCGAACAGCCATGTCAGCCGGAGCCTGAGGCTAAAGACGCTCATCAGGCTGAGATGGCT
CGCGGTTGTCGGGCAAAGCGCCGCGGTCCTGGTTGTCTGGATCGGGCTTGGCTTTCCGCTGCCCGTCATTCCCTGCTTTG
CGCTTATTGCAGCGTCCGCCGCCCTCAACATCTATCTCACTTTCCGTTATCCGAGCGCCCATCTTGTTCCACCGGCGGCC
GCACTTGCGATCCTCACCTTCGATGCCTCGCAACTTGCCGGGCTGCTCTTCCTGACCGGTGGGCTCACAAATCCATTTTC
GCTGCTGATGACGGTACCGGTCGTCATCTCTGCCACGTCCCTGCCGCTCATCTGGACGGGCGTGCTCGGGGCCTATGTGG
TGGTCGTGGCCAGCTTGCTTGCCGTTTTCCACCTGCCGCTTCCCTGGTTTCCGGGGACCGAGCTTGCCATGCCGCTGATC
TATGTGGTGGGCATGCTGATCGCGGTGGTTTCGTCCATCGCATTCACCGGCATCTATGCCTATCGTGTGGCGGAGGAGGC
GCGGCTGCTTGCCAACGCGCTCGCGGCCACGGAGCTGGTTCTGCAGCGCGAGCAGCACATCTCGGCGCTGGACGGCCTGG
CAGCGGCAGCGGCCCATGAACTCGGCACGCCCCTAGCCACGATTGCCCTGGTGGCGCGGGAAATGGAAAAGGCATTGGGA
GATGACACGCGCTTTCGCGAGGACGTCACGCTGCTGCGCTCGCAAAGCGAACGCTGCCGCCAGATCCTGAAGCGGCTTAC
CAGCCTCTCCTCGGAGGGCGAAGCGCATCTGGCGCAACTGCCGCTTACCTCGCTTATCGAAGAGACCGCCGCGCCACACC
GCGATTTCGGCATCGAAATAAAGCTCGCGGCCCAGGAGATGGAAGGGCCTGAACCCGTCGGCCGGCGCAATCCCGGTGTC
ATTTACGGGCTCGGGAACCTGGTGGAGAACGCGGTCGATTTCGCCCGCAGCACAGTGAACATCAGATGGTGGTGGAATGC
GGAATTGGTTCGCATCTCCATTACCGACGACGGGCCTGGCTTTCCCGCCGAAATCATCGATCGTATCGGCGAGCCCTATA
TGTCGCGGCGGCCGGCGGGCAGCTCGAGCGGCGGCGGGCTGGGGCTTGGCCTTTTCATAGCGAAAACGCTTTTGGAACGC
TCCGGGGCTACGGTGCAGTTCGCGAATGCGGGTGGCGAGGGCAAGGGCGCAACCGTGGAAATAAGCTGGCCGCGGGAAAG
ATACCTCGCCGGAGGCGAAGCCTCCGCGCAAGGCTATCAGAAATAA

Upstream 100 bases:

>100_bases
ATGGCCGGAGAATCCGGCCGAAGCAGCGCCGACAAACCGCGCGAAGCCGCGGCAAAAATAATGCTTGGTAAGGAGAAGTC
CGCTGGCTCATAAAAGCTTC

Downstream 100 bases:

>100_bases
CAAAAGCTGGAAAAACGCGGCTTCCTTTCCTAAATTCTTGCATATATCAGCGGGGCCATGATGAACGATACGACAGCCGA
ACAGGCCAATAATATTCCCG

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Protein prrB [H]

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MLEEQRTPNSHVSRSLRLKTLIRLRWLAVVGQSAAVLVVWIGLGFPLPVIPCFALIAASAALNIYLTFRYPSAHLVPPAA
ALAILTFDASQLAGLLFLTGGLTNPFSLLMTVPVVISATSLPLIWTGVLGAYVVVVASLLAVFHLPLPWFPGTELAMPLI
YVVGMLIAVVSSIAFTGIYAYRVAEEARLLANALAATELVLQREQHISALDGLAAAAAHELGTPLATIALVAREMEKALG
DDTRFREDVTLLRSQSERCRQILKRLTSLSSEGEAHLAQLPLTSLIEETAAPHRDFGIEIKLAAQEMEGPEPVGRRNPGV
IYGLGNLVENAVDFARSTVNIRWWWNAELVRISITDDGPGFPAEIIDRIGEPYMSRRPAGSSSGGGLGLGLFIAKTLLER
SGATVQFANAGGEGKGATVEISWPRERYLAGGEASAQGYQK

Sequences:

>Translated_441_residues
MLEEQRTPNSHVSRSLRLKTLIRLRWLAVVGQSAAVLVVWIGLGFPLPVIPCFALIAASAALNIYLTFRYPSAHLVPPAA
ALAILTFDASQLAGLLFLTGGLTNPFSLLMTVPVVISATSLPLIWTGVLGAYVVVVASLLAVFHLPLPWFPGTELAMPLI
YVVGMLIAVVSSIAFTGIYAYRVAEEARLLANALAATELVLQREQHISALDGLAAAAAHELGTPLATIALVAREMEKALG
DDTRFREDVTLLRSQSERCRQILKRLTSLSSEGEAHLAQLPLTSLIEETAAPHRDFGIEIKLAAQEMEGPEPVGRRNPGV
IYGLGNLVENAVDFARSTVNIRWWWNAELVRISITDDGPGFPAEIIDRIGEPYMSRRPAGSSSGGGLGLGLFIAKTLLER
SGATVQFANAGGEGKGATVEISWPRERYLAGGEASAQGYQK
>Mature_441_residues
MLEEQRTPNSHVSRSLRLKTLIRLRWLAVVGQSAAVLVVWIGLGFPLPVIPCFALIAASAALNIYLTFRYPSAHLVPPAA
ALAILTFDASQLAGLLFLTGGLTNPFSLLMTVPVVISATSLPLIWTGVLGAYVVVVASLLAVFHLPLPWFPGTELAMPLI
YVVGMLIAVVSSIAFTGIYAYRVAEEARLLANALAATELVLQREQHISALDGLAAAAAHELGTPLATIALVAREMEKALG
DDTRFREDVTLLRSQSERCRQILKRLTSLSSEGEAHLAQLPLTSLIEETAAPHRDFGIEIKLAAQEMEGPEPVGRRNPGV
IYGLGNLVENAVDFARSTVNIRWWWNAELVRISITDDGPGFPAEIIDRIGEPYMSRRPAGSSSGGGLGLGLFIAKTLLER
SGATVQFANAGGEGKGATVEISWPRERYLAGGEASAQGYQK

Specific function: Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as we

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=233, Percent_Identity=25.3218884120172, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47289; Mature: 47289

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEEQRTPNSHVSRSLRLKTLIRLRWLAVVGQSAAVLVVWIGLGFPLPVIPCFALIAASA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHC
ALNIYLTFRYPSAHLVPPAAALAILTFDASQLAGLLFLTGGLTNPFSLLMTVPVVISATS
EEEEEEEEECCCCCCCCHHHHHHHEEECHHHHHHHHHEECCCCCHHHHHHHHHHHHCCCC
LPLIWTGVLGAYVVVVASLLAVFHLPLPWFPGTELAMPLIYVVGMLIAVVSSIAFTGIYA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRVAEEARLLANALAATELVLQREQHISALDGLAAAAAHELGTPLATIALVAREMEKALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
DDTRFREDVTLLRSQSERCRQILKRLTSLSSEGEAHLAQLPLTSLIEETAAPHRDFGIEI
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHCCCCCCCCEEE
KLAAQEMEGPEPVGRRNPGVIYGLGNLVENAVDFARSTVNIRWWWNAELVRISITDDGPG
EEEHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHEEEEEEEECCEEEEEEECCCCCC
FPAEIIDRIGEPYMSRRPAGSSSGGGLGLGLFIAKTLLERSGATVQFANAGGEGKGATVE
CCHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEE
ISWPRERYLAGGEASAQGYQK
EECCHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MLEEQRTPNSHVSRSLRLKTLIRLRWLAVVGQSAAVLVVWIGLGFPLPVIPCFALIAASA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHC
ALNIYLTFRYPSAHLVPPAAALAILTFDASQLAGLLFLTGGLTNPFSLLMTVPVVISATS
EEEEEEEEECCCCCCCCHHHHHHHEEECHHHHHHHHHEECCCCCHHHHHHHHHHHHCCCC
LPLIWTGVLGAYVVVVASLLAVFHLPLPWFPGTELAMPLIYVVGMLIAVVSSIAFTGIYA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRVAEEARLLANALAATELVLQREQHISALDGLAAAAAHELGTPLATIALVAREMEKALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
DDTRFREDVTLLRSQSERCRQILKRLTSLSSEGEAHLAQLPLTSLIEETAAPHRDFGIEI
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHCCCCCCCCEEE
KLAAQEMEGPEPVGRRNPGVIYGLGNLVENAVDFARSTVNIRWWWNAELVRISITDDGPG
EEEHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHEEEEEEEECCEEEEEEECCCCCC
FPAEIIDRIGEPYMSRRPAGSSSGGGLGLGLFIAKTLLERSGATVQFANAGGEGKGATVE
CCHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEE
ISWPRERYLAGGEASAQGYQK
EECCHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751278; 10358089 [H]