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The map label for this gene is yggW [C]

Identifier: 110636337

GI number: 110636337

Start: 4318707

End: 4319870

Strand: Reverse

Name: yggW [C]

Synonym: Meso_4013

Alternate gene names: 110636337

Gene position: 4319870-4318707 (Counterclockwise)

Preceding gene: 110636338

Following gene: 110636335

Centisome position: 97.9

GC content: 64.26

Gene sequence:

>1164_bases
ATGAACAAGCCGCTCGACGAGGGGCCTGGCTTCGGCGTTTACGTTCACTGGCCCTTCTGCGCGGCCAAATGCCCTTATTG
CGACTTCAACAGCCATGTACGCCACCAGCCGGTAGATCAGGAACGCTTCGCCGCCGCGTTCAAGCGCGAGCTCGCAGCGA
TGCGGGCGCGAACCGGTCCGCGCAGCGTATCCAGCATTTTCCTGGGCGGCGGCACACCCTCTCTGATGGACCCGAAAACA
GTTGGCGCAATCATCGACGCGGTCGCTGCGAGCTGGCACGTTCCGATGGGCGTGGAAATAACGCTGGAGGCCAATCCTTC
CTCCGTGGAGGCGGACCGGTTTCGTGGCTATCGCTCGGCGGGGGTCAACCGCGTTTCCATGGGCATCCAGGCGTTGAACG
ACCGGGATCTGCGCTTTCTCGGCCGCCTCCACAATGTGGAGGAGGCGCTTGGCGCGATCCGGCTCGCGCGCGATCTCTTT
CCGCGCATGTCATTCGACCTGATCTACGCTCGGCCGGGCCAGACGGTGGACGCCTGGAGAGCTGAGCTGGAGGAAGCGGT
CGGATACGCCGCCGATCACTTGTCGCTTTACCAGCTCACAATCGAGGAGGGCACGCCCTTTTATGCGCTGCGCGCGGCCG
GAAAGCTTACCGTACCTGATATGGATCTCGCGGCGGATCTCTATCAGGTGACCCAGGAGATTACGGCCGCGCGCGGCCTT
CCCGCCTACGAGATTTCCAACCACGCCAAACCGGGCGCCGAGAGCCGGCACAACCTGATCTACTGGCGCTATGGCGAATA
TGTGGGCGTCGGGCCAGGCGCCCATGGACGCTTCATCGAGGATGGGCGGCGGGTCGTGACCATGACCGAAAGAAATCCGG
AGACCTGGGCGGCGCTGGTGGAAGCACGCGGCTCAGGCGTGACGGGCGGCGAGATGCTCACGCGCTCGGAAGAGGCGGAC
GAGTTTCTGCTGATGGGGCTGCGGCTGGTGGAAGGAATCGATCTCGATCGCTACGAGAAGCTGGCCGGATTTCCGCTTTC
CCCGCAACGCGTCGCCATCCTGCGCGAGGAAGGGCTGATCGAGCCGGTCGGCAATTCTCGCTTGCGTGCTACACCCGCAG
GGATGGTTGTGCTCGACGCGCTCGTGGCGGACCTGGCGCGCTGA

Upstream 100 bases:

>100_bases
CGGCGGCGGAAAAGCACGGCTGGAAACCGGGGGATGCGCAGGCTCTTTCGCATCGTGCCCGCGCGTTTCAGAAATTCGCA
CGGGCGAGGCTGGGCGTCGC

Downstream 100 bases:

>100_bases
AGCCTCAGCTTGCGCCGGCAAAACTCGACGGTGCGGGGCTGATGAGCCGGGCGGCACCGTCCATCACCTCATAGACCGCA
TAACCACGCTCATTGGTTCC

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MNKPLDEGPGFGVYVHWPFCAAKCPYCDFNSHVRHQPVDQERFAAAFKRELAAMRARTGPRSVSSIFLGGGTPSLMDPKT
VGAIIDAVAASWHVPMGVEITLEANPSSVEADRFRGYRSAGVNRVSMGIQALNDRDLRFLGRLHNVEEALGAIRLARDLF
PRMSFDLIYARPGQTVDAWRAELEEAVGYAADHLSLYQLTIEEGTPFYALRAAGKLTVPDMDLAADLYQVTQEITAARGL
PAYEISNHAKPGAESRHNLIYWRYGEYVGVGPGAHGRFIEDGRRVVTMTERNPETWAALVEARGSGVTGGEMLTRSEEAD
EFLLMGLRLVEGIDLDRYEKLAGFPLSPQRVAILREEGLIEPVGNSRLRATPAGMVVLDALVADLAR

Sequences:

>Translated_387_residues
MNKPLDEGPGFGVYVHWPFCAAKCPYCDFNSHVRHQPVDQERFAAAFKRELAAMRARTGPRSVSSIFLGGGTPSLMDPKT
VGAIIDAVAASWHVPMGVEITLEANPSSVEADRFRGYRSAGVNRVSMGIQALNDRDLRFLGRLHNVEEALGAIRLARDLF
PRMSFDLIYARPGQTVDAWRAELEEAVGYAADHLSLYQLTIEEGTPFYALRAAGKLTVPDMDLAADLYQVTQEITAARGL
PAYEISNHAKPGAESRHNLIYWRYGEYVGVGPGAHGRFIEDGRRVVTMTERNPETWAALVEARGSGVTGGEMLTRSEEAD
EFLLMGLRLVEGIDLDRYEKLAGFPLSPQRVAILREEGLIEPVGNSRLRATPAGMVVLDALVADLAR
>Mature_387_residues
MNKPLDEGPGFGVYVHWPFCAAKCPYCDFNSHVRHQPVDQERFAAAFKRELAAMRARTGPRSVSSIFLGGGTPSLMDPKT
VGAIIDAVAASWHVPMGVEITLEANPSSVEADRFRGYRSAGVNRVSMGIQALNDRDLRFLGRLHNVEEALGAIRLARDLF
PRMSFDLIYARPGQTVDAWRAELEEAVGYAADHLSLYQLTIEEGTPFYALRAAGKLTVPDMDLAADLYQVTQEITAARGL
PAYEISNHAKPGAESRHNLIYWRYGEYVGVGPGAHGRFIEDGRRVVTMTERNPETWAALVEARGSGVTGGEMLTRSEEAD
EFLLMGLRLVEGIDLDRYEKLAGFPLSPQRVAILREEGLIEPVGNSRLRATPAGMVVLDALVADLAR

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=300, Percent_Identity=42.3333333333333, Blast_Score=253, Evalue=2e-67,
Organism=Escherichia coli, GI1789325, Length=325, Percent_Identity=37.5384615384615, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI87082341, Length=319, Percent_Identity=23.8244514106583, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 42527; Mature: 42527

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPLDEGPGFGVYVHWPFCAAKCPYCDFNSHVRHQPVDQERFAAAFKRELAAMRARTGP
CCCCCCCCCCCEEEEECCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
RSVSSIFLGGGTPSLMDPKTVGAIIDAVAASWHVPMGVEITLEANPSSVEADRFRGYRSA
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHCCHHHC
GVNRVSMGIQALNDRDLRFLGRLHNVEEALGAIRLARDLFPRMSFDLIYARPGQTVDAWR
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHH
AELEEAVGYAADHLSLYQLTIEEGTPFYALRAAGKLTVPDMDLAADLYQVTQEITAARGL
HHHHHHHHHHHCCEEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCC
PAYEISNHAKPGAESRHNLIYWRYGEYVGVGPGAHGRFIEDGRRVVTMTERNPETWAALV
CCHHHCCCCCCCCCCCCCEEEEEECCEEECCCCCCCCEECCCCEEEEEECCCHHHHHHHH
EARGSGVTGGEMLTRSEEADEFLLMGLRLVEGIDLDRYEKLAGFPLSPQRVAILREEGLI
HHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHEEEEHHCCCC
EPVGNSRLRATPAGMVVLDALVADLAR
CCCCCCCEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKPLDEGPGFGVYVHWPFCAAKCPYCDFNSHVRHQPVDQERFAAAFKRELAAMRARTGP
CCCCCCCCCCCEEEEECCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
RSVSSIFLGGGTPSLMDPKTVGAIIDAVAASWHVPMGVEITLEANPSSVEADRFRGYRSA
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHCCHHHC
GVNRVSMGIQALNDRDLRFLGRLHNVEEALGAIRLARDLFPRMSFDLIYARPGQTVDAWR
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHH
AELEEAVGYAADHLSLYQLTIEEGTPFYALRAAGKLTVPDMDLAADLYQVTQEITAARGL
HHHHHHHHHHHCCEEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCC
PAYEISNHAKPGAESRHNLIYWRYGEYVGVGPGAHGRFIEDGRRVVTMTERNPETWAALV
CCHHHCCCCCCCCCCCCCEEEEEECCEEECCCCCCCCEECCCCEEEEEECCCHHHHHHHH
EARGSGVTGGEMLTRSEEADEFLLMGLRLVEGIDLDRYEKLAGFPLSPQRVAILREEGLI
HHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHEEEEHHCCCC
EPVGNSRLRATPAGMVVLDALVADLAR
CCCCCCCEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]