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The map label for this gene is gsiC [H]

Identifier: 110636065

GI number: 110636065

Start: 4040466

End: 4041434

Strand: Reverse

Name: gsiC [H]

Synonym: Meso_3740

Alternate gene names: 110636065

Gene position: 4041434-4040466 (Counterclockwise)

Preceding gene: 110636075

Following gene: 110636064

Centisome position: 91.59

GC content: 59.96

Gene sequence:

>969_bases
ATGAGCACCTCTGCCCCCTCCCGCAAACTCCGCTATCGGCCCCCGGTGACACTCCCTTACCTGCTCAGCCGATCGGCAGG
AGCTGTCTTTGCGATCTGGGGTGCGCTGACAATCGTGTTCCTCGCCCTTAATTTGGGCGGAGACCCGGCTTCCTCCCTGG
TATCGCCGTCTGCAAGCGTCGAGGATATCGAGCGTGTGCGCCGCCTCTACGGATACGACCAGCCGCTCCTCGTGCAGTAC
CTGATCTTCTTCAAGAATGTGGCAACCGGCGATTTTCCAAACTCGCTGCGATACGCCACCTCGCCAATGGCATTGGTGTT
CGAACGGTTTCCCAACACGCTGATCCTCGCGCTCTGCGGGATGTCTCTAGGAACCGTCCTGGGCCTTGCAATAGGCTATG
CCTCGGCCTTCGCGAAACATTGGATGTTGCGTGAAATTCCGATGGCCGTCGTGATGGCGCTGCAGGCGTTCCCGCCGATT
CTCCTAGGCGTGCTGCTGGTCCTGGCTTTCTCGATCAAGCTGCGCTGGCTGCCGAGCGCGGGCGGGGGCAGTCCGCTGCA
TCTGGTCCTGCCATCTCTGACGCTAGGCATTTATGTAGCACCGGCAATCGCTCGCGTGTTCCGCACTTCTATTCTGGATG
TCCAGAATGCCGATCATGTCCGCACGGCACTTGCCAAAGGAGTGTCGCCGCGAATGGTCCGGTTGCGCCACGTCGCCGCT
AACGCGCTTATTCCCGTTCTCAATCAGATTGGGCTGCAGCTTGGTGCCATGCTTGGTGGAGCAGTCGTTGTAGAGACGAT
CTTCAGCTGGCCGGGCATCGGGCAGCTCGCCGTAGGCGCGCTTAACAATCAGGACTTCCCGGTTGTCCTGGCAAGCGTGA
GCTTCGTCGCGATCGTTTTCGTCCTGGTCAATCTGCTCGTCGACATCCTGAGCGCGATACTCGATCCGCGCCAAAGGAGC
GTTCAGTGA

Upstream 100 bases:

>100_bases
ACGCTGCCCGAAAGGCTTGCAAAAAATTGAGGAAACGAGCTCCATGCGCACTACTGGCCAACCACTGATCCTGGTCGTCT
CGCGTCGGGAATAATCATAG

Downstream 100 bases:

>100_bases
TAGCCGCTACTCAACCGCAGCGCGGTCGCATTCGAATCGGCATGACAGTGCCCGGCGCCATCGGCATTTCGCTTGTCGTG
CTTATTGTCGGCCTGACAAT

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MSTSAPSRKLRYRPPVTLPYLLSRSAGAVFAIWGALTIVFLALNLGGDPASSLVSPSASVEDIERVRRLYGYDQPLLVQY
LIFFKNVATGDFPNSLRYATSPMALVFERFPNTLILALCGMSLGTVLGLAIGYASAFAKHWMLREIPMAVVMALQAFPPI
LLGVLLVLAFSIKLRWLPSAGGGSPLHLVLPSLTLGIYVAPAIARVFRTSILDVQNADHVRTALAKGVSPRMVRLRHVAA
NALIPVLNQIGLQLGAMLGGAVVVETIFSWPGIGQLAVGALNNQDFPVVLASVSFVAIVFVLVNLLVDILSAILDPRQRS
VQ

Sequences:

>Translated_322_residues
MSTSAPSRKLRYRPPVTLPYLLSRSAGAVFAIWGALTIVFLALNLGGDPASSLVSPSASVEDIERVRRLYGYDQPLLVQY
LIFFKNVATGDFPNSLRYATSPMALVFERFPNTLILALCGMSLGTVLGLAIGYASAFAKHWMLREIPMAVVMALQAFPPI
LLGVLLVLAFSIKLRWLPSAGGGSPLHLVLPSLTLGIYVAPAIARVFRTSILDVQNADHVRTALAKGVSPRMVRLRHVAA
NALIPVLNQIGLQLGAMLGGAVVVETIFSWPGIGQLAVGALNNQDFPVVLASVSFVAIVFVLVNLLVDILSAILDPRQRS
VQ
>Mature_321_residues
STSAPSRKLRYRPPVTLPYLLSRSAGAVFAIWGALTIVFLALNLGGDPASSLVSPSASVEDIERVRRLYGYDQPLLVQYL
IFFKNVATGDFPNSLRYATSPMALVFERFPNTLILALCGMSLGTVLGLAIGYASAFAKHWMLREIPMAVVMALQAFPPIL
LGVLLVLAFSIKLRWLPSAGGGSPLHLVLPSLTLGIYVAPAIARVFRTSILDVQNADHVRTALAKGVSPRMVRLRHVAAN
ALIPVLNQIGLQLGAMLGGAVVVETIFSWPGIGQLAVGALNNQDFPVVLASVSFVAIVFVLVNLLVDILSAILDPRQRSV
Q

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=303, Percent_Identity=38.9438943894389, Blast_Score=207, Evalue=8e-55,
Organism=Escherichia coli, GI1789888, Length=310, Percent_Identity=33.5483870967742, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1787497, Length=306, Percent_Identity=32.3529411764706, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789965, Length=281, Percent_Identity=32.0284697508897, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1787761, Length=327, Percent_Identity=31.8042813455657, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=26.4705882352941, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788504, Length=275, Percent_Identity=26.1818181818182, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34548; Mature: 34416

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSAPSRKLRYRPPVTLPYLLSRSAGAVFAIWGALTIVFLALNLGGDPASSLVSPSASV
CCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCH
EDIERVRRLYGYDQPLLVQYLIFFKNVATGDFPNSLRYATSPMALVFERFPNTLILALCG
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHCCHHHHHHHHH
MSLGTVLGLAIGYASAFAKHWMLREIPMAVVMALQAFPPILLGVLLVLAFSIKLRWLPSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHEEECCC
GGGSPLHLVLPSLTLGIYVAPAIARVFRTSILDVQNADHVRTALAKGVSPRMVRLRHVAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHH
NALIPVLNQIGLQLGAMLGGAVVVETIFSWPGIGQLAVGALNNQDFPVVLASVSFVAIVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHH
VLVNLLVDILSAILDPRQRSVQ
HHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure 
STSAPSRKLRYRPPVTLPYLLSRSAGAVFAIWGALTIVFLALNLGGDPASSLVSPSASV
CCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCH
EDIERVRRLYGYDQPLLVQYLIFFKNVATGDFPNSLRYATSPMALVFERFPNTLILALCG
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHCCHHHHHHHHH
MSLGTVLGLAIGYASAFAKHWMLREIPMAVVMALQAFPPILLGVLLVLAFSIKLRWLPSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHEEECCC
GGGSPLHLVLPSLTLGIYVAPAIARVFRTSILDVQNADHVRTALAKGVSPRMVRLRHVAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHH
NALIPVLNQIGLQLGAMLGGAVVVETIFSWPGIGQLAVGALNNQDFPVVLASVSFVAIVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHH
VLVNLLVDILSAILDPRQRSVQ
HHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA