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The map label for this gene is appC [H]

Identifier: 110636064

GI number: 110636064

Start: 4039591

End: 4040469

Strand: Reverse

Name: appC [H]

Synonym: Meso_3739

Alternate gene names: 110636064

Gene position: 4040469-4039591 (Counterclockwise)

Preceding gene: 110636065

Following gene: 110636063

Centisome position: 91.57

GC content: 60.3

Gene sequence:

>879_bases
GTGATAGCCGCTACTCAACCGCAGCGCGGTCGCATTCGAATCGGCATGACAGTGCCCGGCGCCATCGGCATTTCGCTTGT
CGTGCTTATTGTCGGCCTGACAATCCTGGCGCCCTCGATCTCTCCTTTCTCGCCCTCTGATCAGGACCTCTACAACCTTT
ACGCTGCGCCAAACCTGAACTCGGCGCATATCCTCGGAACCGATGCGATCGGGCAGGATTTGCTGTCGCGCATTTTATAC
GGCGGGCGAATGCCGCTTTTAATCGCCGGCAGCGCCTGCCTGCTTTCCGCAATCGTCGGCGTGGGGCTGGGAGTTCTCGC
CGGAGCGCGCGGAGGCTGGATCGACCAGTTTTTGGGCCGGCTCGCCGATATTCAGCTCGCCATGCCATCGATCATTTTGG
CGCTCGTCCTCCTCGCCTTCGCAGGAGTAAACCTCATCAATCTGGTTATCGTCATCACATTAGCGACCTGGCCATCGCAG
TTCCGGCTGACGCGCGCCCATGCGATGAGCTTGCGCCGGCAGAATTTTATCGAAGCCGCGGAAATGGGGGGCGGATCAAC
CGGGCAGATCATCCTGCGCCATTACCTGCCGAACGTAATGCCGCTTGCTATCGTCACGACCACTCTGAACCTGTCCACAA
GCCTGCTTTTGGAAGCGTCGCTCAGTTATCTTGGTCTAGGCGTCCAGCCGCCAACGCCCGACTGGGGCCAGATGGTCGCC
GCGGGTCAATCGCAGCTTGGCGCCGCATGGTGGCTGTCGGTCGCTCCTGGTGTCATGCTGATGCTCCTCATCCTAGGCAT
TCAGCTCTCCGGGGACTGGCTTGCCGGCCGCCTCTCCGTCCGCGGGATGATCCGTTTTCAGGGCTGGAAAAAGTCATGA

Upstream 100 bases:

>100_bases
TCCTGGCAAGCGTGAGCTTCGTCGCGATCGTTTTCGTCCTGGTCAATCTGCTCGTCGACATCCTGAGCGCGATACTCGAT
CCGCGCCAAAGGAGCGTTCA

Downstream 100 bases:

>100_bases
GCGGACCCGTTCTGGATGTGCAGGGGCTCGTGACCCGACTTGATGGCTCGGCCGGACCGATCATCGCGGTCAACGGCATC
TCCTTCTCTATTGGGCCAGG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MIAATQPQRGRIRIGMTVPGAIGISLVVLIVGLTILAPSISPFSPSDQDLYNLYAAPNLNSAHILGTDAIGQDLLSRILY
GGRMPLLIAGSACLLSAIVGVGLGVLAGARGGWIDQFLGRLADIQLAMPSIILALVLLAFAGVNLINLVIVITLATWPSQ
FRLTRAHAMSLRRQNFIEAAEMGGGSTGQIILRHYLPNVMPLAIVTTTLNLSTSLLLEASLSYLGLGVQPPTPDWGQMVA
AGQSQLGAAWWLSVAPGVMLMLLILGIQLSGDWLAGRLSVRGMIRFQGWKKS

Sequences:

>Translated_292_residues
MIAATQPQRGRIRIGMTVPGAIGISLVVLIVGLTILAPSISPFSPSDQDLYNLYAAPNLNSAHILGTDAIGQDLLSRILY
GGRMPLLIAGSACLLSAIVGVGLGVLAGARGGWIDQFLGRLADIQLAMPSIILALVLLAFAGVNLINLVIVITLATWPSQ
FRLTRAHAMSLRRQNFIEAAEMGGGSTGQIILRHYLPNVMPLAIVTTTLNLSTSLLLEASLSYLGLGVQPPTPDWGQMVA
AGQSQLGAAWWLSVAPGVMLMLLILGIQLSGDWLAGRLSVRGMIRFQGWKKS
>Mature_292_residues
MIAATQPQRGRIRIGMTVPGAIGISLVVLIVGLTILAPSISPFSPSDQDLYNLYAAPNLNSAHILGTDAIGQDLLSRILY
GGRMPLLIAGSACLLSAIVGVGLGVLAGARGGWIDQFLGRLADIQLAMPSIILALVLLAFAGVNLINLVIVITLATWPSQ
FRLTRAHAMSLRRQNFIEAAEMGGGSTGQIILRHYLPNVMPLAIVTTTLNLSTSLLLEASLSYLGLGVQPPTPDWGQMVA
AGQSQLGAAWWLSVAPGVMLMLLILGIQLSGDWLAGRLSVRGMIRFQGWKKS

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=248, Percent_Identity=35.4838709677419, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1787760, Length=257, Percent_Identity=33.4630350194552, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1787498, Length=265, Percent_Identity=34.3396226415094, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1789964, Length=253, Percent_Identity=36.7588932806324, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1789889, Length=238, Percent_Identity=31.0924369747899, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787549, Length=211, Percent_Identity=33.175355450237, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788505, Length=206, Percent_Identity=35.4368932038835, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30878; Mature: 30878

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAATQPQRGRIRIGMTVPGAIGISLVVLIVGLTILAPSISPFSPSDQDLYNLYAAPNLN
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEEECCCCC
SAHILGTDAIGQDLLSRILYGGRMPLLIAGSACLLSAIVGVGLGVLAGARGGWIDQFLGR
CCEEEECHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LADIQLAMPSIILALVLLAFAGVNLINLVIVITLATWPSQFRLTRAHAMSLRRQNFIEAA
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
EMGGGSTGQIILRHYLPNVMPLAIVTTTLNLSTSLLLEASLSYLGLGVQPPTPDWGQMVA
HCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
AGQSQLGAAWWLSVAPGVMLMLLILGIQLSGDWLAGRLSVRGMIRFQGWKKS
CCCHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHEEHHHHEEEEEECCCCCC
>Mature Secondary Structure
MIAATQPQRGRIRIGMTVPGAIGISLVVLIVGLTILAPSISPFSPSDQDLYNLYAAPNLN
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEEECCCCC
SAHILGTDAIGQDLLSRILYGGRMPLLIAGSACLLSAIVGVGLGVLAGARGGWIDQFLGR
CCEEEECHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LADIQLAMPSIILALVLLAFAGVNLINLVIVITLATWPSQFRLTRAHAMSLRRQNFIEAA
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
EMGGGSTGQIILRHYLPNVMPLAIVTTTLNLSTSLLLEASLSYLGLGVQPPTPDWGQMVA
HCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
AGQSQLGAAWWLSVAPGVMLMLLILGIQLSGDWLAGRLSVRGMIRFQGWKKS
CCCHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHEEHHHHEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]