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The map label for this gene is ctaG

Identifier: 110633102

GI number: 110633102

Start: 820925

End: 821533

Strand: Direct

Name: ctaG

Synonym: Meso_0745

Alternate gene names: 110633102

Gene position: 820925-821533 (Clockwise)

Preceding gene: 110633101

Following gene: 110633103

Centisome position: 18.6

GC content: 59.44

Gene sequence:

>609_bases
ATGACGAGCCCTGCCAATCCTTCCGAAGTCACTCGCGACCGGCGCAACCGCGGTGTCGCGTTTGTCTGCGCCGGGGTTTT
CGTGGCGATGGTGGGCATGTCCTTCGCCGCCGTGCCGCTTTACCGGCTTTTCTGCCAGGTCACTGGCTACGGAGGCACGA
CCCAGCGGGTGGAGCAGTATTCGGACACCATCCTCGACCGGACGATCAATGTGCGTTTCGATGCGAACACCAGCGGCGTT
CCCTGGGAGTTCAAGCCCAAGCAGCGCGAGATCACGCTGCGGATCGGCGAGACGACGGAAATCGCCTATGTCGCCCGCAA
CAACGCCCCGACCACGACAACGGGCACGGCCACCTACAATGTCGCGCCCGCTTTGGCGGGAGCCTATTTCAACAAGATCG
AATGCTTCTGCTTCACAAAACAGTCGCTGGAGCCGGGGCAAACCTATGAAATGCCGGTGCAGTTCTTTGTCGATCCAGAG
ATCGTGAACGTACCGGAACTGAAAAATCTGAAGACCATCACGCTTTCCTACACCTTCTACCCGAATAATCAGGAGTCGGC
GGAAGGGCCGGCTGAAGGTGCGGCAAAGACCCAGAAGCTCGGGGGATAA

Upstream 100 bases:

>100_bases
GCGATCGCTCTTGCGCTGATCGCCTTCGTGGTCATCGTTTACCTGGGTACGGTGCTCAAGCTTGGCCCGGCCGTCTTTAG
CCGGGGGATGTGAGGATAGG

Downstream 100 bases:

>100_bases
AATGGCAGACGCCCACGCAAAAAAACACGATTACCACATCATCGATCCGAGCCCCTGGCCATTCATCGCCTCCGTCGGCG
CGCTAGTCATGGCGCTGGGT

Product: cytochrome C oxidase assembly protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MTSPANPSEVTRDRRNRGVAFVCAGVFVAMVGMSFAAVPLYRLFCQVTGYGGTTQRVEQYSDTILDRTINVRFDANTSGV
PWEFKPKQREITLRIGETTEIAYVARNNAPTTTTGTATYNVAPALAGAYFNKIECFCFTKQSLEPGQTYEMPVQFFVDPE
IVNVPELKNLKTITLSYTFYPNNQESAEGPAEGAAKTQKLGG

Sequences:

>Translated_202_residues
MTSPANPSEVTRDRRNRGVAFVCAGVFVAMVGMSFAAVPLYRLFCQVTGYGGTTQRVEQYSDTILDRTINVRFDANTSGV
PWEFKPKQREITLRIGETTEIAYVARNNAPTTTTGTATYNVAPALAGAYFNKIECFCFTKQSLEPGQTYEMPVQFFVDPE
IVNVPELKNLKTITLSYTFYPNNQESAEGPAEGAAKTQKLGG
>Mature_201_residues
TSPANPSEVTRDRRNRGVAFVCAGVFVAMVGMSFAAVPLYRLFCQVTGYGGTTQRVEQYSDTILDRTINVRFDANTSGVP
WEFKPKQREITLRIGETTEIAYVARNNAPTTTTGTATYNVAPALAGAYFNKIECFCFTKQSLEPGQTYEMPVQFFVDPEI
VNVPELKNLKTITLSYTFYPNNQESAEGPAEGAAKTQKLGG

Specific function: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I

COG id: COG3175

COG function: function code O; Cytochrome oxidase assembly factor

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX11/CtaG family

Homologues:

Organism=Homo sapiens, GI4758034, Length=188, Percent_Identity=42.0212765957447, Blast_Score=147, Evalue=6e-36,
Organism=Homo sapiens, GI242247057, Length=141, Percent_Identity=39.7163120567376, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI242247061, Length=133, Percent_Identity=42.1052631578947, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71990692, Length=178, Percent_Identity=41.0112359550562, Blast_Score=148, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6325125, Length=176, Percent_Identity=40.9090909090909, Blast_Score=146, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24581944, Length=196, Percent_Identity=44.8979591836735, Blast_Score=163, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COXZ_MESSB (Q11KD0)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_673310.1
- ProteinModelPortal:   Q11KD0
- SMR:   Q11KD0
- STRING:   Q11KD0
- GeneID:   4180223
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_0745
- NMPDR:   fig|266779.1.peg.2883
- eggNOG:   COG3175
- HOGENOM:   HBG525908
- OMA:   PVSFYID
- PhylomeDB:   Q11KD0
- ProtClustDB:   PRK05089
- BioCyc:   MSP266779:MESO_0745-MONOMER
- HAMAP:   MF_00155
- InterPro:   IPR007533
- Gene3D:   G3DSA:2.60.370.10
- PANTHER:   PTHR21320
- PIRSF:   PIRSF005413

Pfam domain/function: PF04442 CtaG_Cox11; SSF110111 CtaG_Cox11

EC number: NA

Molecular weight: Translated: 22238; Mature: 22107

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x126613ac)-;

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPANPSEVTRDRRNRGVAFVCAGVFVAMVGMSFAAVPLYRLFCQVTGYGGTTQRVEQY
CCCCCCHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SDTILDRTINVRFDANTSGVPWEFKPKQREITLRIGETTEIAYVARNNAPTTTTGTATYN
HHHHHCCEEEEEECCCCCCCCCEECCCCEEEEEEECCCEEEEEEEECCCCCCCCCCEEEE
VAPALAGAYFNKIECFCFTKQSLEPGQTYEMPVQFFVDPEIVNVPELKNLKTITLSYTFY
CHHHHHHHHHCCEEEEEEECCCCCCCCEEECCEEEEECCCEECCCCCCCEEEEEEEEEEC
PNNQESAEGPAEGAAKTQKLGG
CCCCCCCCCCCCCCHHHHCCCH
>Mature Secondary Structure 
TSPANPSEVTRDRRNRGVAFVCAGVFVAMVGMSFAAVPLYRLFCQVTGYGGTTQRVEQY
CCCCCHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SDTILDRTINVRFDANTSGVPWEFKPKQREITLRIGETTEIAYVARNNAPTTTTGTATYN
HHHHHCCEEEEEECCCCCCCCCEECCCCEEEEEEECCCEEEEEEEECCCCCCCCCCEEEE
VAPALAGAYFNKIECFCFTKQSLEPGQTYEMPVQFFVDPEIVNVPELKNLKTITLSYTFY
CHHHHHHHHHCCEEEEEEECCCCCCCCEEECCEEEEECCCEECCCCCCCEEEEEEEEEEC
PNNQESAEGPAEGAAKTQKLGG
CCCCCCCCCCCCCCHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA