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The map label for this gene is ctaE [H]

Identifier: 110633103

GI number: 110633103

Start: 821535

End: 822416

Strand: Direct

Name: ctaE [H]

Synonym: Meso_0746

Alternate gene names: 110633103

Gene position: 821535-822416 (Clockwise)

Preceding gene: 110633102

Following gene: 110633104

Centisome position: 18.62

GC content: 59.75

Gene sequence:

>882_bases
ATGGCAGACGCCCACGCAAAAAAACACGATTACCACATCATCGATCCGAGCCCCTGGCCATTCATCGCCTCCGTCGGCGC
GCTAGTCATGGCGCTGGGTGCCATCGCGTGGATGAAAGCGGCACAGGGCAGCTCGTTCCCGGTCTTCGGGATCGACCTTG
CGGCATCAAGGTTCTGGCTGTTCCTGATCGGCCTCCTGATCATCCTCTACACCATGTTCTCGTGGTGGAGCGACACGATC
AGGGAAGGGCAGGAAGGGCATCATACGGCTGTCGTATCGCTTCATCTGCGCTACGGCATGATCATGTTCATCGCCTCCGA
GCTTATGTTCTTCGTGGCGTGGTTCTGGGCGTTTTTCGATGCAAGCCTCTTCCCTGGCGATCCATCTCAGGTAAGCCGCG
CGGAGTTCACGGGCGGAACCTGGCCGCCGCACGGGGTGGAAGTGCTCGATCCTTTCCACCTGCCGCTTTACAACACGATC
ATCCTGCTGCTGTCGGGCACGACGGTCACCTGGGCGCACCATGCGTTGCTTGAGAACGACCGCAAGGGGCTCGTGGCCGG
GCTTGCCGTCACCGTGGCGCTTGGCATCCTCTTCAGCTTCGTGCAGGCCTATGAATATATGCACGCGCCGTTTGCCTTCA
GCGATTCCATCTATGGCGCTACCTTCTTCATGGCGACCGGCTTCCATGGTTTCCACGTGATCGTCGGCACCATCTTCCTT
GCCGTCTGCCTTCTTCGGGCCATGGCGGGGCAGTTTACGCCGAAGCAGCACTTTGGTTTCGAGGCTGCGGCCTGGTATTG
GCACTTCGTCGACGTGGTCTGGCTGTTCCTCTTCGCCTTCATCTATGTCTGGGCGTCGGCGGGTGCCACAATCGCGCATT
AG

Upstream 100 bases:

>100_bases
AAGACCATCACGCTTTCCTACACCTTCTACCCGAATAATCAGGAGTCGGCGGAAGGGCCGGCTGAAGGTGCGGCAAAGAC
CCAGAAGCTCGGGGGATAAA

Downstream 100 bases:

>100_bases
GAAGAGCTTTGAATGCAAAGGGGGCGGCCGCTGGGAAGGCGGCTGCCCCTTGCTTTTTGGAATACCGCAATAGGGCGGAA
AGAGTGCTTGGACCGGCCGA

Product: cytochrome c oxidase, subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III; Oxidase aa(3) subunit 3 [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MADAHAKKHDYHIIDPSPWPFIASVGALVMALGAIAWMKAAQGSSFPVFGIDLAASRFWLFLIGLLIILYTMFSWWSDTI
REGQEGHHTAVVSLHLRYGMIMFIASELMFFVAWFWAFFDASLFPGDPSQVSRAEFTGGTWPPHGVEVLDPFHLPLYNTI
ILLLSGTTVTWAHHALLENDRKGLVAGLAVTVALGILFSFVQAYEYMHAPFAFSDSIYGATFFMATGFHGFHVIVGTIFL
AVCLLRAMAGQFTPKQHFGFEAAAWYWHFVDVVWLFLFAFIYVWASAGATIAH

Sequences:

>Translated_293_residues
MADAHAKKHDYHIIDPSPWPFIASVGALVMALGAIAWMKAAQGSSFPVFGIDLAASRFWLFLIGLLIILYTMFSWWSDTI
REGQEGHHTAVVSLHLRYGMIMFIASELMFFVAWFWAFFDASLFPGDPSQVSRAEFTGGTWPPHGVEVLDPFHLPLYNTI
ILLLSGTTVTWAHHALLENDRKGLVAGLAVTVALGILFSFVQAYEYMHAPFAFSDSIYGATFFMATGFHGFHVIVGTIFL
AVCLLRAMAGQFTPKQHFGFEAAAWYWHFVDVVWLFLFAFIYVWASAGATIAH
>Mature_292_residues
ADAHAKKHDYHIIDPSPWPFIASVGALVMALGAIAWMKAAQGSSFPVFGIDLAASRFWLFLIGLLIILYTMFSWWSDTIR
EGQEGHHTAVVSLHLRYGMIMFIASELMFFVAWFWAFFDASLFPGDPSQVSRAEFTGGTWPPHGVEVLDPFHLPLYNTII
LLLSGTTVTWAHHALLENDRKGLVAGLAVTVALGILFSFVQAYEYMHAPFAFSDSIYGATFFMATGFHGFHVIVGTIFLA
VCLLRAMAGQFTPKQHFGFEAAAWYWHFVDVVWLFLFAFIYVWASAGATIAH

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=281, Percent_Identity=47.3309608540925, Blast_Score=241, Evalue=6e-64,
Organism=Escherichia coli, GI1786633, Length=139, Percent_Identity=30.9352517985612, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6226542, Length=286, Percent_Identity=33.5664335664336, Blast_Score=164, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 32713; Mature: 32582

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADAHAKKHDYHIIDPSPWPFIASVGALVMALGAIAWMKAAQGSSFPVFGIDLAASRFWL
CCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHH
FLIGLLIILYTMFSWWSDTIREGQEGHHTAVVSLHLRYGMIMFIASELMFFVAWFWAFFD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHC
ASLFPGDPSQVSRAEFTGGTWPPHGVEVLDPFHLPLYNTIILLLSGTTVTWAHHALLEND
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCC
RKGLVAGLAVTVALGILFSFVQAYEYMHAPFAFSDSIYGATFFMATGFHGFHVIVGTIFL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHH
AVCLLRAMAGQFTPKQHFGFEAAAWYWHFVDVVWLFLFAFIYVWASAGATIAH
HHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ADAHAKKHDYHIIDPSPWPFIASVGALVMALGAIAWMKAAQGSSFPVFGIDLAASRFWL
CCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHH
FLIGLLIILYTMFSWWSDTIREGQEGHHTAVVSLHLRYGMIMFIASELMFFVAWFWAFFD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHC
ASLFPGDPSQVSRAEFTGGTWPPHGVEVLDPFHLPLYNTIILLLSGTTVTWAHHALLEND
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCC
RKGLVAGLAVTVALGILFSFVQAYEYMHAPFAFSDSIYGATFFMATGFHGFHVIVGTIFL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHH
AVCLLRAMAGQFTPKQHFGFEAAAWYWHFVDVVWLFLFAFIYVWASAGATIAH
HHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3019767; 2832167; 7651515 [H]