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The map label for this gene is ywlC [H]

Identifier: 110633072

GI number: 110633072

Start: 790378

End: 791334

Strand: Direct

Name: ywlC [H]

Synonym: Meso_0715

Alternate gene names: 110633072

Gene position: 790378-791334 (Clockwise)

Preceding gene: 110633071

Following gene: 110633073

Centisome position: 17.91

GC content: 66.98

Gene sequence:

>957_bases
ATGGCCGAAATTCTGCGTGAGGAGATTGCCCTTGACGCAGCCTGCCGCCTGTTGGCGGCGGGAGAGCCCGTTGCGATCCC
CACGGAGACGGTTTACGGCCTTGCCGCGGATGCACGCAATGGAGAGGCGGTCGCGCGGATTTTCGAGGCGAAGGGCAGGC
CCCGCTTCAATCCGTTGATCGCCCATATGGCCGATCTCGAAATGGCAGGGCGCTTCGCGGTTTTTTCTCCGCTGGCCCTG
CGCCTCGCGCAGGCCTTCTGGCCCGGCCCGCTTACGCTCGTGCTTCCCCATCGCCCGGATTTGGGCATCCACCCGCTGGT
GACCGCCGGGCTCGACACCCTGGCGCTCCGTTGCCCCCAGGGCTTTGCAGCCAATGTCATTGCACGGTTCGGCCGCCCGC
TCGCGGCCCCCAGCGCCAACATTTCCGGCCGCGTGACGGGCACCACGGCTGAGGCGGTGAACGCCGCGCTGGGCGATCGC
ATCAGGCTTGTCGTTGATGGGGGACCCGCAAGGGTCGGGCTGGAATCCACCATTGTGAAAGTGGCGGACGAAACGCTCAT
TCTTTTGCGCCCCGGAGGGCTTGCGGCGGAGGAGATCGAGCGTGTTGCCGGCATGTCCCTGAAACGCGGCGCAAATGGCG
TGCAGGCCCCTGGCATGCTGGCGTCGCATTATGCACCGCATGCCGCGATCAGGCTCGACGCTTCCGAGGTTTTGGCGGGC
GAAGCCCTGCTTGGTTTCGGGCCGGACCGGGCGAAGGGCGCGGATCAAGCGGCGATGGTGCTCAATCTTTCGCCTTCGGG
CGATCTGCGTGAGGCCGCGGCGAACCTCTTTTCTCACCTTGCCACGCTCGATGCTGGGGGCGCCAAAACCATTGCAGTCG
AGCCCGTGCCGCGGCACGGGCTGGGCGAGGCGATCAACGACCGTCTGGCCCGCGCCGCCGCGCCGAGGGATCAGTGA

Upstream 100 bases:

>100_bases
TTCTCGAAGATCGCTGGCTGAAGCAGGGTTCTATCCATGCAAAGCCTTGCTCCCGGCCTTCCATCGGGATAGGCACCCTG
GAAGGTAAAGGGAAAAGAGC

Downstream 100 bases:

>100_bases
AGAGGTGACCGCCGATGAACGCTGAGACGAACACGCTTGATCCAGCGCTTGCGGATCGCTTTGCGGCCATTGTCGGCGAG
CGCCATGCGCTCAGGGATGA

Product: translation factor SUA5

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MAEILREEIALDAACRLLAAGEPVAIPTETVYGLAADARNGEAVARIFEAKGRPRFNPLIAHMADLEMAGRFAVFSPLAL
RLAQAFWPGPLTLVLPHRPDLGIHPLVTAGLDTLALRCPQGFAANVIARFGRPLAAPSANISGRVTGTTAEAVNAALGDR
IRLVVDGGPARVGLESTIVKVADETLILLRPGGLAAEEIERVAGMSLKRGANGVQAPGMLASHYAPHAAIRLDASEVLAG
EALLGFGPDRAKGADQAAMVLNLSPSGDLREAAANLFSHLATLDAGGAKTIAVEPVPRHGLGEAINDRLARAAAPRDQ

Sequences:

>Translated_318_residues
MAEILREEIALDAACRLLAAGEPVAIPTETVYGLAADARNGEAVARIFEAKGRPRFNPLIAHMADLEMAGRFAVFSPLAL
RLAQAFWPGPLTLVLPHRPDLGIHPLVTAGLDTLALRCPQGFAANVIARFGRPLAAPSANISGRVTGTTAEAVNAALGDR
IRLVVDGGPARVGLESTIVKVADETLILLRPGGLAAEEIERVAGMSLKRGANGVQAPGMLASHYAPHAAIRLDASEVLAG
EALLGFGPDRAKGADQAAMVLNLSPSGDLREAAANLFSHLATLDAGGAKTIAVEPVPRHGLGEAINDRLARAAAPRDQ
>Mature_317_residues
AEILREEIALDAACRLLAAGEPVAIPTETVYGLAADARNGEAVARIFEAKGRPRFNPLIAHMADLEMAGRFAVFSPLALR
LAQAFWPGPLTLVLPHRPDLGIHPLVTAGLDTLALRCPQGFAANVIARFGRPLAAPSANISGRVTGTTAEAVNAALGDRI
RLVVDGGPARVGLESTIVKVADETLILLRPGGLAAEEIERVAGMSLKRGANGVQAPGMLASHYAPHAAIRLDASEVLAGE
ALLGFGPDRAKGADQAAMVLNLSPSGDLREAAANLFSHLATLDAGGAKTIAVEPVPRHGLGEAINDRLARAAAPRDQ

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321269, Length=375, Percent_Identity=33.0666666666667, Blast_Score=138, Evalue=9e-34,
Organism=Drosophila melanogaster, GI78707274, Length=204, Percent_Identity=31.3725490196078, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 32960; Mature: 32829

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEILREEIALDAACRLLAAGEPVAIPTETVYGLAADARNGEAVARIFEAKGRPRFNPLI
CHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEEECCCCCCHHHHHHHHHCCCCCCCHHH
AHMADLEMAGRFAVFSPLALRLAQAFWPGPLTLVLPHRPDLGIHPLVTAGLDTLALRCPQ
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHCHHHHHEECCC
GFAANVIARFGRPLAAPSANISGRVTGTTAEAVNAALGDRIRLVVDGGPARVGLESTIVK
CHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHH
VADETLILLRPGGLAAEEIERVAGMSLKRGANGVQAPGMLASHYAPHAAIRLDASEVLAG
CCCCEEEEECCCCCCHHHHHHHHCCHHHCCCCCCCCCCHHHHHCCCCEEEEECHHHHHHC
EALLGFGPDRAKGADQAAMVLNLSPSGDLREAAANLFSHLATLDAGGAKTIAVEPVPRHG
CHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
LGEAINDRLARAAAPRDQ
CHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AEILREEIALDAACRLLAAGEPVAIPTETVYGLAADARNGEAVARIFEAKGRPRFNPLI
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEEECCCCCCHHHHHHHHHCCCCCCCHHH
AHMADLEMAGRFAVFSPLALRLAQAFWPGPLTLVLPHRPDLGIHPLVTAGLDTLALRCPQ
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHCHHHHHEECCC
GFAANVIARFGRPLAAPSANISGRVTGTTAEAVNAALGDRIRLVVDGGPARVGLESTIVK
CHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHH
VADETLILLRPGGLAAEEIERVAGMSLKRGANGVQAPGMLASHYAPHAAIRLDASEVLAG
CCCCEEEEECCCCCCHHHHHHHHCCHHHCCCCCCCCCCHHHHHCCCCEEEEECHHHHHHC
EALLGFGPDRAKGADQAAMVLNLSPSGDLREAAANLFSHLATLDAGGAKTIAVEPVPRHG
CHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
LGEAINDRLARAAAPRDQ
CHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]