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The map label for this gene is exoN [H]

Identifier: 110633016

GI number: 110633016

Start: 736580

End: 737476

Strand: Direct

Name: exoN [H]

Synonym: Meso_0659

Alternate gene names: 110633016

Gene position: 736580-737476 (Clockwise)

Preceding gene: 110633015

Following gene: 110633017

Centisome position: 16.69

GC content: 59.09

Gene sequence:

>897_bases
ATGAAGAAAGTCAGGAAAGCCGTTATTCCCGTCGCCGGACTTGGAACCCGTTTTCTGCCGGCTACCAAGGCGCTGCCCAA
GGAAATGCTCACGATCGTCGATAAGCCTGTCGTGCAATATGCCGTCGACGAGGCGCTGGAGGCTGGCATCGAACACATCA
TCTTCGTCACCGGGCGCAACAAGGCCGTTATCGAGGACTATTTCGATCTTCAGCCGGAATTGGCCGGTACGCTCGAAAAG
GCAGGCAAGACCAAGGAATTGCGTCTTCTTGAGGAGATGATGCCTGTTGCGGGCTCGGTGAGCTTCACCCGCCAGCAGGC
ACCGCTCGGCCTCGGTCACGCGGTTTGGTGCGCCCGTGACATTGTGGGCAACGAACCTTTCGCCGTGCTCCTGCCGGATA
TGGTTTCCTTTGGCAAAAAGGGCTGCCTCGCCGAGGCCATGGAGCTCTATGGCCGCACAGGCGGCAATGTTCTGGCTGTA
GAGCAATGCCATCCCCGCGAAACACGCAAATACGGCATTGTCGGGCGCGGTGCCGAGGTGGTGCCTGGCTTCCAGATCAC
CAGCATGGTTGAAAAACCCGCGCCGGAAAATGCGCCGTCGAACTTCTACATCAACGGGCGCTACATCTTGCAGCCCGAGA
TATTCGAGTTCTTGAGCCGTCACGAGCGCGGCGCCGGCAACGAGATCCAGATCACCGACGCCATGGCTCATCTGCTAAGG
GAGCAGCCTTTCTATGCGCGGCCGTTCACGGGCCGCATGTTCGATTGCGGCTCAAAATCCGGCTTCATCGAAGCCAATGT
CGCCTTCGCGCTGAAGCGGGACGACATCAGGGAAAGTGTCATCGAGCCCATCCGCGCCATGGTCGGCATGGACAGAGAAA
CCGGACAGGCTGCTTGA

Upstream 100 bases:

>100_bases
AGAACAGCGGCGAAGAAGCCGCAATCTATGGGACGGGGGATTACACCGCAGCGCTTTTTTGTGGCGGCTGCACAGTTCTA
ATACCTCAAGGGATATTGCA

Downstream 100 bases:

>100_bases
GCCGCGGACCGTTGACCGCTTCCACCTTCGCGGTGGAAGCGGCCGCTCGAATGCGTGGTCGGACCCGCATGAAGCTTCCG
CGAGAAAGACAAGAGGATCG

Product: UDP-glucose pyrophosphorylase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MKKVRKAVIPVAGLGTRFLPATKALPKEMLTIVDKPVVQYAVDEALEAGIEHIIFVTGRNKAVIEDYFDLQPELAGTLEK
AGKTKELRLLEEMMPVAGSVSFTRQQAPLGLGHAVWCARDIVGNEPFAVLLPDMVSFGKKGCLAEAMELYGRTGGNVLAV
EQCHPRETRKYGIVGRGAEVVPGFQITSMVEKPAPENAPSNFYINGRYILQPEIFEFLSRHERGAGNEIQITDAMAHLLR
EQPFYARPFTGRMFDCGSKSGFIEANVAFALKRDDIRESVIEPIRAMVGMDRETGQAA

Sequences:

>Translated_298_residues
MKKVRKAVIPVAGLGTRFLPATKALPKEMLTIVDKPVVQYAVDEALEAGIEHIIFVTGRNKAVIEDYFDLQPELAGTLEK
AGKTKELRLLEEMMPVAGSVSFTRQQAPLGLGHAVWCARDIVGNEPFAVLLPDMVSFGKKGCLAEAMELYGRTGGNVLAV
EQCHPRETRKYGIVGRGAEVVPGFQITSMVEKPAPENAPSNFYINGRYILQPEIFEFLSRHERGAGNEIQITDAMAHLLR
EQPFYARPFTGRMFDCGSKSGFIEANVAFALKRDDIRESVIEPIRAMVGMDRETGQAA
>Mature_298_residues
MKKVRKAVIPVAGLGTRFLPATKALPKEMLTIVDKPVVQYAVDEALEAGIEHIIFVTGRNKAVIEDYFDLQPELAGTLEK
AGKTKELRLLEEMMPVAGSVSFTRQQAPLGLGHAVWCARDIVGNEPFAVLLPDMVSFGKKGCLAEAMELYGRTGGNVLAV
EQCHPRETRKYGIVGRGAEVVPGFQITSMVEKPAPENAPSNFYINGRYILQPEIFEFLSRHERGAGNEIQITDAMAHLLR
EQPFYARPFTGRMFDCGSKSGFIEANVAFALKRDDIRESVIEPIRAMVGMDRETGQAA

Specific function: May Play A Role In Stationary Phase Survival. [C]

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=266, Percent_Identity=25.9398496240602, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI11761619, Length=266, Percent_Identity=25.9398496240602, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1787488, Length=282, Percent_Identity=42.5531914893617, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1788355, Length=280, Percent_Identity=40, Blast_Score=187, Evalue=9e-49,
Organism=Escherichia coli, GI1790224, Length=296, Percent_Identity=25.3378378378378, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 32825; Mature: 32825

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVRKAVIPVAGLGTRFLPATKALPKEMLTIVDKPVVQYAVDEALEAGIEHIIFVTGRN
CCCHHHHHCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
KAVIEDYFDLQPELAGTLEKAGKTKELRLLEEMMPVAGSVSFTRQQAPLGLGHAVWCARD
CCHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHH
IVGNEPFAVLLPDMVSFGKKGCLAEAMELYGRTGGNVLAVEQCHPRETRKYGIVGRGAEV
HHCCCCCEEECHHHHHHCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHCCCCCCCCCCC
VPGFQITSMVEKPAPENAPSNFYINGRYILQPEIFEFLSRHERGAGNEIQITDAMAHLLR
CCCHHHHHHHHCCCCCCCCCCEEECCEEEECHHHHHHHHHHCCCCCCEEEEHHHHHHHHH
EQPFYARPFTGRMFDCGSKSGFIEANVAFALKRDDIRESVIEPIRAMVGMDRETGQAA
CCCCCCCCCCCCEECCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKKVRKAVIPVAGLGTRFLPATKALPKEMLTIVDKPVVQYAVDEALEAGIEHIIFVTGRN
CCCHHHHHCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
KAVIEDYFDLQPELAGTLEKAGKTKELRLLEEMMPVAGSVSFTRQQAPLGLGHAVWCARD
CCHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHH
IVGNEPFAVLLPDMVSFGKKGCLAEAMELYGRTGGNVLAVEQCHPRETRKYGIVGRGAEV
HHCCCCCEEECHHHHHHCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHCCCCCCCCCCC
VPGFQITSMVEKPAPENAPSNFYINGRYILQPEIFEFLSRHERGAGNEIQITDAMAHLLR
CCCHHHHHHHHCCCCCCCCCCEEECCEEEECHHHHHHHHHHCCCCCCEEEEHHHHHHHHH
EQPFYARPFTGRMFDCGSKSGFIEANVAFALKRDDIRESVIEPIRAMVGMDRETGQAA
CCCCCCCCCCCCEECCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8226645; 8226646; 8246891; 11481431 [H]