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The map label for this gene is msrB [H]

Identifier: 110632740

GI number: 110632740

Start: 421683

End: 422192

Strand: Reverse

Name: msrB [H]

Synonym: Meso_0379

Alternate gene names: 110632740

Gene position: 422192-421683 (Counterclockwise)

Preceding gene: 110632742

Following gene: 110632726

Centisome position: 9.57

GC content: 63.92

Gene sequence:

>510_bases
ATGAGACGTCGCAATTTTCTCTTGGGCAGCGCCGGTGCGATCGTCGCCCTCGGGGGCGGTGCATTCGTCCTGCGCGGCCG
CCCCGGCGCGGACGCCTCCGCGGAGGAATTCGAGATCACGAAGACCGAGGAGGAATGGCGCAGGATCCTAACGCCGCAGC
AATATGCCGTATTGCGGGAAGAGGATACTGAGCCCGCGTTCAGCAGCCCGTTGAACGAGGAGAAACGGGCCGGCATGTTC
CATTGCGCCGGCTGCGACCTGCCGGTGTATTCGTCCGCGGCGAAATACGAGTCCGGCACGGGCTGGCCGAGCTTCTGGGA
ATCTCTGCCCAATGCCATCGGCACGAAGGAGGACAATTCCTTCTTCATGACACGAACCGAGTGCCATTGCCGGCGCTGCG
GCGGGCATCTCGGCCACATCTTCGAGGATGGTCCGCCGCCCACCGGAAAGCGCCATTGCCTAAATGGGTTGGCGCTCGCC
TTCAGGCCGGCAGAGACGCAAAGCGGGTGA

Upstream 100 bases:

>100_bases
TCACGAGCGCAAATGACGAAGTGACGCCGACCGCTCACGCGCCCTTGATTTGCCGCCTGGCTTCGCCTCCCCTACTCTCA
GGAGAGACGGAGGAGAAACG

Downstream 100 bases:

>100_bases
CGCGCGGCGACCGACGGAAACTTTAGCCAGCCGTCACAGCGTGCACGATTGCGGCGCGCAATTCCTCCAGCCCTTCCCCC
TTTTCCGACGAGGTGGCAAT

Product: methionine-R-sulfoxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MRRRNFLLGSAGAIVALGGGAFVLRGRPGADASAEEFEITKTEEEWRRILTPQQYAVLREEDTEPAFSSPLNEEKRAGMF
HCAGCDLPVYSSAAKYESGTGWPSFWESLPNAIGTKEDNSFFMTRTECHCRRCGGHLGHIFEDGPPPTGKRHCLNGLALA
FRPAETQSG

Sequences:

>Translated_169_residues
MRRRNFLLGSAGAIVALGGGAFVLRGRPGADASAEEFEITKTEEEWRRILTPQQYAVLREEDTEPAFSSPLNEEKRAGMF
HCAGCDLPVYSSAAKYESGTGWPSFWESLPNAIGTKEDNSFFMTRTECHCRRCGGHLGHIFEDGPPPTGKRHCLNGLALA
FRPAETQSG
>Mature_169_residues
MRRRNFLLGSAGAIVALGGGAFVLRGRPGADASAEEFEITKTEEEWRRILTPQQYAVLREEDTEPAFSSPLNEEKRAGMF
HCAGCDLPVYSSAAKYESGTGWPSFWESLPNAIGTKEDNSFFMTRTECHCRRCGGHLGHIFEDGPPPTGKRHCLNGLALA
FRPAETQSG

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=130, Percent_Identity=44.6153846153846, Blast_Score=127, Evalue=4e-30,
Organism=Homo sapiens, GI301336162, Length=130, Percent_Identity=44.6153846153846, Blast_Score=127, Evalue=4e-30,
Organism=Homo sapiens, GI73089054, Length=130, Percent_Identity=44.6153846153846, Blast_Score=127, Evalue=4e-30,
Organism=Homo sapiens, GI37620216, Length=130, Percent_Identity=44.6153846153846, Blast_Score=127, Evalue=6e-30,
Organism=Homo sapiens, GI117606353, Length=134, Percent_Identity=46.2686567164179, Blast_Score=126, Evalue=1e-29,
Organism=Escherichia coli, GI1788077, Length=124, Percent_Identity=43.5483870967742, Blast_Score=112, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17553450, Length=126, Percent_Identity=37.3015873015873, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115532676, Length=126, Percent_Identity=37.3015873015873, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319816, Length=128, Percent_Identity=40.625, Blast_Score=103, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24645799, Length=140, Percent_Identity=38.5714285714286, Blast_Score=109, Evalue=7e-25,
Organism=Drosophila melanogaster, GI221378664, Length=133, Percent_Identity=39.0977443609023, Blast_Score=109, Evalue=8e-25,
Organism=Drosophila melanogaster, GI221378662, Length=140, Percent_Identity=37.1428571428571, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI45553335, Length=130, Percent_Identity=40, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI21356369, Length=130, Percent_Identity=40, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24645801, Length=151, Percent_Identity=35.7615894039735, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24645804, Length=141, Percent_Identity=36.8794326241135, Blast_Score=103, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 18552; Mature: 18552

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRRNFLLGSAGAIVALGGGAFVLRGRPGADASAEEFEITKTEEEWRRILTPQQYAVLRE
CCCCCEEEECCCEEEEECCCEEEEECCCCCCCCCCCEEEECCHHHHHHHCCCCHHEEEEC
EDTEPAFSSPLNEEKRAGMFHCAGCDLPVYSSAAKYESGTGWPSFWESLPNAIGTKEDNS
CCCCCCCCCCCCCHHHCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
FFMTRTECHCRRCGGHLGHIFEDGPPPTGKRHCLNGLALAFRPAETQSG
EEEEHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCC
>Mature Secondary Structure
MRRRNFLLGSAGAIVALGGGAFVLRGRPGADASAEEFEITKTEEEWRRILTPQQYAVLRE
CCCCCEEEECCCEEEEECCCEEEEECCCCCCCCCCCEEEECCHHHHHHHCCCCHHEEEEC
EDTEPAFSSPLNEEKRAGMFHCAGCDLPVYSSAAKYESGTGWPSFWESLPNAIGTKEDNS
CCCCCCCCCCCCCHHHCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
FFMTRTECHCRRCGGHLGHIFEDGPPPTGKRHCLNGLALAFRPAETQSG
EEEEHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA